Leading pharmaceutical innovation: trends and drivers for growth in the pharmaceutical industry ; with 20 tables
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2004
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturverz. S. 159 - 163 |
| Beschreibung: | XI, 178 S. graph. Darst., Kt. |
| ISBN: | 3540407170 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV017430874 | ||
| 003 | DE-604 | ||
| 005 | 20070326 | ||
| 007 | t | ||
| 008 | 030819s2004 gw bd|| |||| 00||| eng d | ||
| 016 | 7 | |a 968516084 |2 DE-101 | |
| 020 | |a 3540407170 |9 3-540-40717-0 | ||
| 035 | |a (OCoLC)314627473 | ||
| 035 | |a (DE-599)BVBBV017430874 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 044 | |a gw |c DE | ||
| 049 | |a DE-N2 |a DE-20 |a DE-703 |a DE-945 |a DE-19 |a DE-M382 |a DE-11 |a DE-2070s | ||
| 082 | 0 | |a 330 | |
| 082 | 0 | |a 338.476151 | |
| 084 | |a QR 525 |0 (DE-625)142044: |2 rvk | ||
| 100 | 1 | |a Gassmann, Oliver |d 1967- |e Verfasser |0 (DE-588)115376232 |4 aut | |
| 245 | 1 | 0 | |a Leading pharmaceutical innovation |b trends and drivers for growth in the pharmaceutical industry ; with 20 tables |c Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2004 | |
| 300 | |a XI, 178 S. |b graph. Darst., Kt. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Literaturverz. S. 159 - 163 | ||
| 650 | 0 | 7 | |a Innovationsmanagement |0 (DE-588)4161817-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Arzneimittelmarkt |0 (DE-588)4003131-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Innovationswettbewerb |0 (DE-588)4192032-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Erfolgsfaktor |0 (DE-588)4197034-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pharmazeutische Industrie |0 (DE-588)4045696-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Marktentwicklung |0 (DE-588)4123713-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Pharmazeutische Industrie |0 (DE-588)4045696-1 |D s |
| 689 | 0 | 1 | |a Innovationsmanagement |0 (DE-588)4161817-8 |D s |
| 689 | 0 | 2 | |a Erfolgsfaktor |0 (DE-588)4197034-2 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Arzneimittelmarkt |0 (DE-588)4003131-7 |D s |
| 689 | 1 | 1 | |a Innovationswettbewerb |0 (DE-588)4192032-6 |D s |
| 689 | 1 | 2 | |a Marktentwicklung |0 (DE-588)4123713-4 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Reepmeyer, Gerrit |e Verfasser |4 aut | |
| 700 | 1 | |a Zedtwitz, Maximilian von |d 1969- |e Verfasser |0 (DE-588)120671417 |4 aut | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010502711&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-010502711 | ||
Datensatz im Suchindex
| _version_ | 1804130243471998976 |
|---|---|
| adam_text | CONTENTS
PREFACE V
CONTENTS IX
I. INNOVATION AS A KEY SUCCESS FACTOR IN THE PHARMACEUTICAL
INDUSTRY 1
THE PRODUCTIVITY PARADOX 1
THE BLOCKBUSTER IMPERATIVE 5
STRATEGIES FOR GROWTH 10
DO YOU WANT TO BE IN THIS INDUSTRY? 13
BARGAINING POWER OF SUPPLIERS 15
BARGAINING POWER OF BUYERS 15
RISK OF ENTRY FROM POTENTIAL COMPETITORS 16
THREAT OF SUBSTITUTE PRODUCTS 17
REGULATIVE FORCES 17
RIVALRY AMONG ESTABLISHED COMPANIES 18
DIFFERENTIATION VIA CLINICAL PROFILES 19
ENTERING THE MARKET QUICKLY 20
CONCLUSIONS 21
II. PHARMACEUTICAL INNOVATION: THE CASE OF SWITZERLAND 23
LARGEST ECONOMIC VALUE-ADDED OF GDP IN SWITZERLAND 23
STABLE MARKET GROWTH 25
SOUND PRODUCTIVITY AND EMPLOYMENT 30
STRONG SUPPORT BY INDUSTRY ASSOCIATIONS 31
HIGHLY GLOBAL ORIENTATION 33
COMPLEX INDUSTRY AND PRODUCT CLASSIFICATION 34
FRAGMENTED MARKET STRUCTURE 39
CONJOINED FINANCING SYSTEMS 43
STRICT NEW DRUG REGISTRATION 44
ACCURATE PRICE REGULATION 50
III. THE SCIENCE AND TECHNOLOGY CHALLENGE: HOW TO FIND NEW
DRUGS 53
RISE OF THE BIOTECHNOLOGY INDUSTRY: BOOSTING INNOVATION 53
HIGH-THROUGHPUT SCREENING: FAIL EARLIER, SUCCEED SOONER 58
COMBINATORIAL CHEMISTRY: CUT EXPERIMENTAL CYCLE TIMES 59
BIOINFORMATICS: MORE THAN 100 GIGABYTE OF DATA PER DAY 60
PROTEOMICS: PROFITING FROM THE HUMAN GENOME PROJECT 62
GENOMICS: TOWARDS INDIYIDUALIZATION AND MASS CUSTOMIZATION ....63
PHARMACOGENOMICS: CREATE TAILOR-MADE DRUGS 66
MOLECULAR DESIGN: FROM EXPERIMENTING TO ANALYTIC DESIGN 67
CONCLUSIONS 68
IV. THE PIPELINE MANAGEMENT CHALLENGE: HOW TO SHAPE THE
INNOVATION-FLOW 71
THE IMPORTANCE OF PIPELINE MANAGEMENT 71
THE COMPLEXITY OF DRUG DISCOVERY 75
THE DIFFERENT PHASES OF THE R&D PROCESS 79
THE R&D PROCESS AT HOFFMANN-LA ROCHE 82
CONCLUSIONS 85
V. THE OUTSOURCING AND INTERNATIONALIZATION CHALLENGE: HOW TO
HARNESS OUTSIDE INNOVATION 87
IMPACT OF OUTSOURCING ON THE PHARMACEUTICAL VALUE CHAIN 87
SUCCESSFUL COMMERCIALIZATION OF A BREAKTHROUGH TECHNOLOGY 91
TRENDS AND DRIVERS OF INTERNATIONALIZATION 97
R&D INTERNATIONALIZATION OF SWISS PHARMACEUTICAL COMPANIES... 102
LOCATIONS OF PHARMACEUTICAL R&D ABROAD 106
THREE PRINCIPAL PROBLEMS OF INTERNATIONAL R&D 110
CONCLUSIONS 114
VI. MANAGEMENT ANSWERS TO PHARMACEUTICAL R&D CHALLENGES ...117
MANAGING THE RESEARCH-TO-DEVELOPMENT HANDOVER 117
MANAGING HUMAN RESOURCES 119
MANAGING PROJECTS AND THE PORTFOLIO 121
MANAGING OUTSOURCING ACTIVITIES 124
MANAGING INTELLECTUAL PROPERTY RIGHTS 127
MANAGING R&D STRATEGY AT SCHERING 131
MANAGING VIRTUAL PROJECT MANAGEMENT POOLS AT ROCHE 133
MANAGING UNCERTAINTY AT ROCHE 135
MANAGING KNOW-HOW TRANSFER AT KAO 136
CONCLUSIONS 137
VII. FUTURE DIRECTIONS AND TRENDS 139
VIII. APPENDICES 143
CASE: R&D MANAGEMENT AT NOVARTIS 143
CASE: R&D MANAGEMENT AT ROCHE 151
BIBLIOGRAPHY 159
INDEX 165
GLOSSARY 171
AUTHORS 177
|
| any_adam_object | 1 |
| author | Gassmann, Oliver 1967- Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969- |
| author_GND | (DE-588)115376232 (DE-588)120671417 |
| author_facet | Gassmann, Oliver 1967- Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969- |
| author_role | aut aut aut |
| author_sort | Gassmann, Oliver 1967- |
| author_variant | o g og g r gr m v z mv mvz |
| building | Verbundindex |
| bvnumber | BV017430874 |
| classification_rvk | QR 525 |
| ctrlnum | (OCoLC)314627473 (DE-599)BVBBV017430874 |
| dewey-full | 330 338.476151 |
| dewey-hundreds | 300 - Social sciences |
| dewey-ones | 330 - Economics 338 - Production |
| dewey-raw | 330 338.476151 |
| dewey-search | 330 338.476151 |
| dewey-sort | 3330 |
| dewey-tens | 330 - Economics |
| discipline | Wirtschaftswissenschaften |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02299nam a2200529 c 4500</leader><controlfield tag="001">BV017430874</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20070326 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">030819s2004 gw bd|| |||| 00||| eng d</controlfield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">968516084</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3540407170</subfield><subfield code="9">3-540-40717-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)314627473</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV017430874</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">gw</subfield><subfield code="c">DE</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-N2</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-945</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-M382</subfield><subfield code="a">DE-11</subfield><subfield code="a">DE-2070s</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">330</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">338.476151</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">QR 525</subfield><subfield code="0">(DE-625)142044:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Gassmann, Oliver</subfield><subfield code="d">1967-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)115376232</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Leading pharmaceutical innovation</subfield><subfield code="b">trends and drivers for growth in the pharmaceutical industry ; with 20 tables</subfield><subfield code="c">Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Berlin [u.a.]</subfield><subfield code="b">Springer</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XI, 178 S.</subfield><subfield code="b">graph. Darst., Kt.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Literaturverz. S. 159 - 163</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Innovationsmanagement</subfield><subfield code="0">(DE-588)4161817-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arzneimittelmarkt</subfield><subfield code="0">(DE-588)4003131-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Innovationswettbewerb</subfield><subfield code="0">(DE-588)4192032-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Erfolgsfaktor</subfield><subfield code="0">(DE-588)4197034-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmazeutische Industrie</subfield><subfield code="0">(DE-588)4045696-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Marktentwicklung</subfield><subfield code="0">(DE-588)4123713-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Pharmazeutische Industrie</subfield><subfield code="0">(DE-588)4045696-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Innovationsmanagement</subfield><subfield code="0">(DE-588)4161817-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Erfolgsfaktor</subfield><subfield code="0">(DE-588)4197034-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Arzneimittelmarkt</subfield><subfield code="0">(DE-588)4003131-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Innovationswettbewerb</subfield><subfield code="0">(DE-588)4192032-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Marktentwicklung</subfield><subfield code="0">(DE-588)4123713-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Reepmeyer, Gerrit</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zedtwitz, Maximilian von</subfield><subfield code="d">1969-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)120671417</subfield><subfield code="4">aut</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010502711&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-010502711</subfield></datafield></record></collection> |
| id | DE-604.BV017430874 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:17:56Z |
| institution | BVB |
| isbn | 3540407170 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010502711 |
| oclc_num | 314627473 |
| open_access_boolean | |
| owner | DE-N2 DE-20 DE-703 DE-945 DE-19 DE-BY-UBM DE-M382 DE-11 DE-2070s |
| owner_facet | DE-N2 DE-20 DE-703 DE-945 DE-19 DE-BY-UBM DE-M382 DE-11 DE-2070s |
| physical | XI, 178 S. graph. Darst., Kt. |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Springer |
| record_format | marc |
| spelling | Gassmann, Oliver 1967- Verfasser (DE-588)115376232 aut Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz Berlin [u.a.] Springer 2004 XI, 178 S. graph. Darst., Kt. txt rdacontent n rdamedia nc rdacarrier Literaturverz. S. 159 - 163 Innovationsmanagement (DE-588)4161817-8 gnd rswk-swf Arzneimittelmarkt (DE-588)4003131-7 gnd rswk-swf Innovationswettbewerb (DE-588)4192032-6 gnd rswk-swf Erfolgsfaktor (DE-588)4197034-2 gnd rswk-swf Pharmazeutische Industrie (DE-588)4045696-1 gnd rswk-swf Marktentwicklung (DE-588)4123713-4 gnd rswk-swf Pharmazeutische Industrie (DE-588)4045696-1 s Innovationsmanagement (DE-588)4161817-8 s Erfolgsfaktor (DE-588)4197034-2 s DE-604 Arzneimittelmarkt (DE-588)4003131-7 s Innovationswettbewerb (DE-588)4192032-6 s Marktentwicklung (DE-588)4123713-4 s Reepmeyer, Gerrit Verfasser aut Zedtwitz, Maximilian von 1969- Verfasser (DE-588)120671417 aut DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010502711&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gassmann, Oliver 1967- Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969- Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables Innovationsmanagement (DE-588)4161817-8 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Innovationswettbewerb (DE-588)4192032-6 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Marktentwicklung (DE-588)4123713-4 gnd |
| subject_GND | (DE-588)4161817-8 (DE-588)4003131-7 (DE-588)4192032-6 (DE-588)4197034-2 (DE-588)4045696-1 (DE-588)4123713-4 |
| title | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables |
| title_auth | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables |
| title_exact_search | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables |
| title_full | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_fullStr | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_full_unstemmed | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry ; with 20 tables Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_short | Leading pharmaceutical innovation |
| title_sort | leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry with 20 tables |
| title_sub | trends and drivers for growth in the pharmaceutical industry ; with 20 tables |
| topic | Innovationsmanagement (DE-588)4161817-8 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Innovationswettbewerb (DE-588)4192032-6 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Marktentwicklung (DE-588)4123713-4 gnd |
| topic_facet | Innovationsmanagement Arzneimittelmarkt Innovationswettbewerb Erfolgsfaktor Pharmazeutische Industrie Marktentwicklung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010502711&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT gassmannoliver leadingpharmaceuticalinnovationtrendsanddriversforgrowthinthepharmaceuticalindustrywith20tables AT reepmeyergerrit leadingpharmaceuticalinnovationtrendsanddriversforgrowthinthepharmaceuticalindustrywith20tables AT zedtwitzmaximilianvon leadingpharmaceuticalinnovationtrendsanddriversforgrowthinthepharmaceuticalindustrywith20tables |