Tumor suppressor genes: 1 Pathways and isolation strategies
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, N.J.
Humana Press
2003
|
| Schriftenreihe: | Methods in molecular biology
222 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | e-book: 1-59259-328-3 |
| Beschreibung: | XIX, 504 S. Ill., graph. Darst. |
| ISBN: | 0896039862 1592593283 |
Internformat
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Datensatz im Suchindex
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| adam_text | Contents
Preface v
Contents of Companion Volume ix
Contributors xiii
Part I. Known Tumor Suppressor Genes and Pathways
1 Growth Control by the Retinoblastoma Gene Family
Marco G. Paggi, Armando Felsani, and Antonio Giordano 3
2 The APC Tumor Suppressor Pathway
Patrice J. Morin and Ashani T. Weeraratna 21
3 Hereditary Breast and Ovarian Cancer Genes
Ralph Scully and Nadine Puget 41
4 Hereditary Colon Cancer Genes
William M. Grady and Sanford D. Markowitz 59
5 Patched, Hedgehog, and Skin Cancer
Anthony G. Ouinn and Ervin Epstein, Jr. 85
6 Tumor Suppressor Genes in Lung Cancer
ArvindK. Virmani and Adi F. Gaidar 97
7 TP53, hChk2, and the Li Fraumeni Syndrome
Jenny Varley 117
8 Genetic Alterations in Esophageal Cancer
Jun ichi Okano, Lorraine Snyder, and Anil K. Rustgi 131
9 PTEN and Cancer
Ramon Parsons and Laura Simpson 147
10 VHL and Kidney Cancer
Michael Ohh and William G. Kaelin, Jr. 167
11 p16INK4A and Familial Melanoma
Kapaettu Satyamoorthy and Meenhard Herlyn 185
12 The INK4a/ARF Locus and Human Cancer
Greg H. Enders 197
13 Progression Model of Prostate Cancer
Teresa Acosta Almeida and Nickolas Papadopoulos 211
14 Neurofibromatosis Type 1
Margaret E. McLaughlin and Tyler Jacks 223
15 Wilms Tumor as a Model for Cancer Biology
Andrew P. Feinberg and Bryan R. G. Williams 239
vii
viii Contents
16 Inadequate Caretaker Gene Function
and Human Cancer Development
Theodore L. DeWeese and William G. Nelson 249
17 The Regulation of Tumor Suppressor Genes by Oncogenes
Paul Dent, Liang Qiao, Donna Gilfor, Michael Birrer,
Steven Grant, and Paul B. Fisher 269
Part II. Identification of Tumor Suppressor Genes
18 Determination of Cancer Allelotype
Jennifer J. Ascano and Steven M. Powell 295
19 Epidemiological Approaches to the Identification
of Cancer Predisposition Genes
Timothy R. Rebbeck 309
20 Characterization of Translocations in Human Cancer
Keri Fair and Michelle M. Le Beau 327
21 Positional Approaches to Cancer Genetics
Gavin P. Robertson, Linda Sargent, and Mark A. Nelson 339
22 Hybrid Capture of Putative Tumor Suppressor Genes
Bryan L. Betz and Bernard E. Weissman 365
23 Approaches to Proteomic Analysis of Human Tumors
Mamoun Ahram and Michael R. Emmert Buck 375
24 Representational Difference Analysis of Gene Expression
James M. Bugni and Norman R. Drinkwater 385
25 Antisense Libraries to Isolate Tumor Suppressor Genes
AdiKimchi 399
26 Genetic Suppressor Elements in the Characterization
and Identification of Tumor Suppressor Genes
Igor B. Roninson and Andrei V. Gudkov 413
27 Cross linking Subtractive Hybridization
to Identify Tumor Suppressor Genes
Gen Sheng Wu 437
28 Suppression Subtractive Hybridization for Identification
and Functional Analysis of Tumor Suppressor Genes
luri D. Louro, Evans C. Bailey, and J. Michael Ruppert 453
29 SAGE as a Strategy to Isolate Cancer Related Genes
Kathy Boon and Gregory J. Riggins 463
30 Differential Display Techniques to Identify Tumor Suppressor
Gene Pathways
Siham Biade and Maureen E. Murphy 481
31 Detection of Mismatch Repair Gene Expression
in Urologic Malignancies
Fredrick S. Leach 491
Index 501
Contents of the Companion Volume
Volume 2: Regulation, Function, and Medicinal Applications
Part I. Understanding the Function and Regulation of Tumor Suppressor Genes
1 Utilizing NMR to Study the Structure of Growth Inhibitory Proteins
Francesca M. Marassi
2 Generation and Application of Phospho specific Antibodies
for p53 and pRB
Yoichi Taya, Kiichiro Nakajima, Kumiko Yoshizawa Kumagaye,
and Katsuyuki Tamai
3 Stability and Ubiquitination of the Tumor Suppressor Protein p53
Lesley J. Jardine and Carl G. Maki
4 Role of Tumor Suppressors in DNA Damage Response
Bin Bing S. Zhou, Michael R. Mattern, and Kum Kum Khanna
5 In Situ Hybridization in Cancer and Normal Tissue
Shrihari Kadkol, Jeremy Juang, and Tzyy choou Wu
6 Genetic Strategies in Saccharomyces cerevisiae
to Study Human Tumor Suppressor Genes
Takahiko Kobayashi, Ting Wang, Hua Qian,
and Rainer K. Brachmann
7 Electrophoretic Mobility Shift Analysis of the DNA Binding
of Tumor Suppressor Genes
Edward C. Thornborrow, Matthew Maurer, and James J. Manfredi
8 Analysis of Gene Promoter Regulation by Tumor Suppressor Genes
Kumaravel Somasundaram, Sanjeev Das, Smita Lakhotia,
and Narendra Wajapeyee
9 DNA Footprinting
M. Stacey Ricci and Wafik S. El Deiry
10 Identification of DNA Binding of Tumor Suppressor Genes
by Chromatin Immunoprecipitation
Timothy K. MacLachlan and Wafik S. El Deiry
11 Coimmunoprecipitation of Tumor Suppressor Protein Interacting Proteins
Li Kuo Su
12 Microarray Approaches for Analysis of Tumor Suppressor Gene Function
Sally A. Amundson and Albert J. Fornace, Jr.
13 Analysis of Tumor Suppressor Gene Induced Senescence
Judith Campisi
14 Yeast Two Hybrid Screening as a Means
of Deciphering Tumor Suppressor Pathways
E. Robert McDonald III and Wafik S. El Deiry
15 Somatic Cell Knockouts of Tumor Suppressor Genes
Ruth Hemmer, Wenyi Wei, Annie Dutriaux, and John M. Sedivy
ix
x Contents of Companion Volume
16 Colony Growth Suppression by Tumor Suppressor Genes
Gen Sheng Wu
17 Flow Cytometric Analysis of Cell Cycle Control
by Tumor Suppressor Genes
David T. Dicker and Wafik S. El Deiry
18 Analysis of Cyclin Dependent Kinase Activity
Timothy K. MacLachlan and Wafik S. El Deiry
19 Tumor Suppressor Gene lnducible Cell Lines
Michael Dohn, Susan Nozell, Amy Willis, and Xinbin Chen
20 In Vitro Models of Early Neoplastic Transformation
of Human Mammary Epithelial Cells
Vimla Band
21 Tumor Suppression Through Angiogenesis Inhibition
Andrew M. Arsham and M. Celeste Simon
22 Flow Cytometric Analysis of Tumor Suppressor Gene Induced Apoptosis
David T. Dicker and Wafik S. El Deiry
23 Functional Analysis of Tumor Suppressor Genes in Mice
Stephen N. Jones and Lawrence A. Donehower
24 The Tissue Microenvironment as an Epigenetic Tumor Modifier
Meredith linger and Valerie M. Weaver
25 Analyzing the Function of Tumor Suppressor Genes
Using a Drosophila Model
Raymond A. Pagliarini, Ana T. Quinones, and Tian Xu
26 Assembling a Tumor Progression Model
Mark Redston
27 Conformation Sensitive Gel Electrophoresis
for Detecting BRCA1 Mutations
Smita Lakhotia and Kumaravel Somasundaram
Part II. Medicinal Applications of Tumor Suppressors
28 Conversion Technology and Cancer Predispositions
Nickolas Papadopoulos
29 Discovering Novel Anticancer Drugs:
Practical Aspects and Recent Advances
Cristina T. Lewis and Patrick M. O Connor
30 Targets in Apoptosis Signaling:
Promise of Selective Anticancer Therapy
Ramadevi Nimmanapalli and Kapil Bhalla
31 Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function
Zhong Yun and Amato J. Giaccia
32 Hormonal and Differentiation Agents in Cancer Growth Suppression
Mikhail V. Blagosklonny
33 Regulation of NF kB by Oncoproteins and Tumor Suppressor Proteins
Lee V. Madrid and Albert S. Baldwin, Jr.
Contents of Companion Volume xi
34 Blocking Survivin to Kill Cancer Cells
Dario C. Altieri
35 Targeting the Mitochondria to Enhance Tumor Suppression
Eyal Gottlieb and Craig B. Thompson
36 Novel Approaches to Screen for Anticancer Drugs
Using Saccharomyces cerevisiae
Julian A. Simon and Timothy J. Yen
37 Tumor Suppressor Gene Therapy
Jack A. Roth and Susan F. Grammer
38 Therapeutic Strategies Using Inhibitors of Angiogenesis
Michael S. O Reilly
39 Isolation of p53 Inhibitors by Screening Chemical Libraries
in Cell Based Readout System
Andrei V. Gudkov and Elena Komarova
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| language | English |
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| spelling | Tumor suppressor genes 1 Pathways and isolation strategies edited by Wafik S. El-Deiry Totowa, N.J. Humana Press 2003 XIX, 504 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 222 Methods in molecular biology ... e-book: 1-59259-328-3 Labortechnik (DE-588)4123602-6 gnd rswk-swf Tumorsuppressor-Gen (DE-588)4326903-5 gnd rswk-swf Tumorsuppressor-Gen (DE-588)4326903-5 s Labortechnik (DE-588)4123602-6 s DE-604 El-Deiry, Wafik S. Sonstige oth (DE-604)BV014668841 1 Methods in molecular biology 222 (DE-604)BV035362695 222 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010442967&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Tumor suppressor genes |
| title_auth | Tumor suppressor genes |
| title_exact_search | Tumor suppressor genes |
| title_full | Tumor suppressor genes 1 Pathways and isolation strategies edited by Wafik S. El-Deiry |
| title_fullStr | Tumor suppressor genes 1 Pathways and isolation strategies edited by Wafik S. El-Deiry |
| title_full_unstemmed | Tumor suppressor genes 1 Pathways and isolation strategies edited by Wafik S. El-Deiry |
| title_short | Tumor suppressor genes |
| title_sort | tumor suppressor genes pathways and isolation strategies |
| topic | Labortechnik (DE-588)4123602-6 gnd Tumorsuppressor-Gen (DE-588)4326903-5 gnd |
| topic_facet | Labortechnik Tumorsuppressor-Gen |
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