Analysis and purification methods in combinatorial chemistry:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley-Interscience
2004
|
| Schriftenreihe: | Chemical analysis
163 |
| Schlagworte: | |
| Online-Zugang: | Publisher description Table of contents Inhaltsverzeichnis |
| Beschreibung: | XIII, 466 S. Ill., graph. Darst. |
| ISBN: | 0471269298 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804130159961309184 |
|---|---|
| adam_text | IMAGE 1
ANALYSIS AND PURIFICATION
METHODS IN COMBINATORIAL CHEMISTRY
EDITED BY BING YAN
WILEY- INTERSCIENCE A JOHN WILEY & SONS, INC, PUBLICATION
IMAGE 2
CONTENTS
PREFACE CONTRIBUTORS
IX
XI
PART I ANALYSIS FOR FEASIBILITY AND OPTIMIZATION OF LIBRARY SYNTHESIS 1
CHAPTER 1 QUANTITATIVE ANALYSIS IN ORGANIC SYNTHESIS WITH NMR
SPECTROSCOPY 3
LAURA H. LUCAS AND CYNTHIA K. LARIVE
CHAPTER 2 19 F GEL-PHASE NMR SPECTROSCOPY FOR REACTION MONITORING AND
QUANTIFICATION OF RESIN LOADING 37
JOSEPH M. SALVINO
CHAPTER 3 THE APPLICATION OF SINGLE-BEAD FTIR AND COLOR TEST FOR
REACTION MONITORING AND BUILDING BLOCK VALIDATION IN COMBINATORIAL
LIBRARY SYNTHESIS S3
JASON J. COURNOYER, CLINTON A. KRUEGER, JANICE V. WADE, AND BING YAN
CHAPTER 4 HR-MAS NMR ANALYSIS OF COMPOUNDS ATTACHED TO POLYMER SUPPORTS
71
MERITXELT GUINO AND YOTANDA R. DE MIGUEL
IMAGE 3
VI
CONTENTS
CHAPTER 5 MULTTVARIATE TOOLS FOR REAL-TIME MONITORING AND OPTIMIZATION
OF COMBINATORIAL MATERIALS AND PROCESS CONDITIONS 87
RADISLAV A POTYRAILO, RONALD J. WROCZYNSKI, JOHN P. LEMMON, WILLIAM P.
FLANAGAN, AND OLTEA P. SICLOVAN
CHAPTER 6 MASS SPECTROMETRY AND SOLUBLE POLYMERIC SUPPORT 125
CHRISTINE ENJALBAL, FREDERIC LAMATY, JEAN MARTINEZ, AND JEAN-LOUIS
AUBAGNAC
PART II HIGH-THROUGHPUT ANALYSIS FOR LIBRARY QUALITY CONTROL 137
CHAPTER 7 HIGH-THROUGHPUT NMR TECHNIQUES FOR COMBINATORIAL CHEMICAL
LIBRARY ANALYSIS 139
TING HOU AND DANIEL RAFTERY
CHAPTER 8 MICELLAR ELECTROKINETIC CHROMATOGRAPHY AS A TOOL FOR
COMBINATORIAL CHEMISTRY ANALYSIS: THEORY AND APPLICATIONS 175
PETER J. SIMMS
CHAPTER 9 CHARACTERIZATION OF SPLIT-POOL ENCODED COMBINATORIAL LIBRARIES
209
JING JIM ZHANG AND WILLIAM L. FITCH
PART HI HIGH-THROUGHPUT PURIFICATION TO IMPROVE LIBRARY QUALITY
CHAPTER ID STRATEGIES AND METHODS FOR PURIFYING ORGANIC COMPOUNDS AND
COMBINATORIAL LIBRARIES JIANG ZHAO, LU ZHANG, AND BING YAN
253
255
IMAGE 4
CONTENTS VLL
CHAPTER 11 HIGH-THROUGHPUT PURIFICATION:
TRIAGE AND OPTIMIZATION 281
JILL HOCHLOWSKI
CHAPTER 12 PARALLEL HPLC IN HIGH- THROUGHPUT ANALYSIS AND PURIFICATION
307
RALF GOD AND HOLGER GUMM
PART IV ANALYSIS FOR COMPOUND STABILITY AND DRUGABILITY 321
CHAPTER 13 ORGANIC COMPOUND STABILITY IN LARGE, DIVERSE PHARMACEUTICAL
SCREENING COLLECTION 323
KENNETH L. MORAND AND XUEHENG CHENG
CHAPTER 14 QUARTZ CRYSTAL MICROBALANCE IN BIOMOLECULAR RECOGNITION 351
MING-CHUNG TSENG, I-NAN CHANG, AND YEN-HO CHU
CHAPTER 15 HIGH-THROUGHPUT PHYSICOCHEMICAL PROFILING; POTENTIAL AND
LIMITATIONS 369
BERNARD FALLER
CHAPTER 16 SOLUBILITY IN THE DESIGN OF COMBINATORIAL LIBRARIES 407
CHRISTOPHER LIPINSKI
CHAPTER 17 HIGH-THROUGHPUT DETERMINATION OF LOG/) VALUES BY LC/MS METHOD
435 JENNY D. VITLENA, KEN WLASICHUK, DONALD E. SCHMIDT JR., AND JAMES J.
BAO
INDEX 457
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| illustrated | Illustrated |
| indexdate | 2024-07-09T19:16:36Z |
| institution | BVB |
| isbn | 0471269298 |
| language | English |
| lccn | 2003014606 |
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| physical | XIII, 466 S. Ill., graph. Darst. |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Wiley-Interscience |
| record_format | marc |
| series | Chemical analysis |
| series2 | Chemical analysis |
| spelling | Analysis and purification methods in combinatorial chemistry ed. by Bing Yan Hoboken, NJ Wiley-Interscience 2004 XIII, 466 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Chemical analysis 163 Química farmacêutica larpcal Combinatorial chemistry Chemische Analyse (DE-588)4009840-0 gnd rswk-swf Kombinatorische Synthese (DE-588)4513555-1 gnd rswk-swf Kombinatorische Synthese (DE-588)4513555-1 s Chemische Analyse (DE-588)4009840-0 s DE-604 Yan, Bing Sonstige oth Chemical analysis 163 (DE-604)BV000008780 163 http://www.loc.gov/catdir/description/wiley038/2003014606.html Publisher description http://www.loc.gov/catdir/toc/wiley032/2003014606.html Table of contents GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010441151&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Analysis and purification methods in combinatorial chemistry Chemical analysis Química farmacêutica larpcal Combinatorial chemistry Chemische Analyse (DE-588)4009840-0 gnd Kombinatorische Synthese (DE-588)4513555-1 gnd |
| subject_GND | (DE-588)4009840-0 (DE-588)4513555-1 |
| title | Analysis and purification methods in combinatorial chemistry |
| title_auth | Analysis and purification methods in combinatorial chemistry |
| title_exact_search | Analysis and purification methods in combinatorial chemistry |
| title_full | Analysis and purification methods in combinatorial chemistry ed. by Bing Yan |
| title_fullStr | Analysis and purification methods in combinatorial chemistry ed. by Bing Yan |
| title_full_unstemmed | Analysis and purification methods in combinatorial chemistry ed. by Bing Yan |
| title_short | Analysis and purification methods in combinatorial chemistry |
| title_sort | analysis and purification methods in combinatorial chemistry |
| topic | Química farmacêutica larpcal Combinatorial chemistry Chemische Analyse (DE-588)4009840-0 gnd Kombinatorische Synthese (DE-588)4513555-1 gnd |
| topic_facet | Química farmacêutica Combinatorial chemistry Chemische Analyse Kombinatorische Synthese |
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