Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP):
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
2002
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Ulm, Univ., Diss., 2003 |
| Beschreibung: | 99 Bl. graph. Darst. : 30 cm |
Internformat
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Datensatz im Suchindex
| _version_ | 1816445080590876672 |
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TABLE OF CONTENTS
INTRODUCTION
8
CHAPTER A: NOCICEPTION
1. PAIN. CLASSIFICATION OF PAIN AND NEURAL PATHWAYS OF PAIN PERCEPTION
10
2. AMPHIBIAN SYMPATHETIC GANGLIA 13
3. ION CHANNELS 15
4 M-CURRENT 15
5. NEUROTRANSMITTER 17
6. PHARMACOLOGICAL APPROACH TO PAIN TREATMENT 17
CHAPTER B: ATP
1. ATP. HISTORY, SYNTHESIS AND DEGRADATION
2. PURINERGIC RECEPTORS: P
2
X AND P
2
V CLASS
3. TRANSDUCTION MECHANISMS
3.1 G-PROTEIN
3.2 PHOSPHOLIPASE C (PLC)
3.3 INOSITOL 1,3,5 TRISPHOSPHATE (IPJ)
3.4 DIACYLGLYCEROL (DAG)
'T
3.5 PROTEINKINASE C (PKC)
22
27
30
32
32
32
33
CHAPTER C: MATERIAL AND METHODS
1. EXPERIMENTAL ANIMALS
2. PREPARATION AND DISSECTION
3. PREPARATION OF SOLUTIONS
4 PREPARATION AND CLASSIFICATION OF DRUGS
4.1 ATP
MUSCARINE
OXOTREMORINE
THAPSIGARGIN
35
35
36
37
37
37
38
38
4.2
4.3
4.4
4
BIBLIOGRAFISCHE INFORMATIONEN
HTTP://D-NB.INFO/966532414
4.5 CHELERYTHRINE 38
4.6 U-73122 (ACTIVE) 39
4.7 U-73343 (NOT ACTIVE) 39
5. RECORDING
5.1 VOLTAGE CLAMP 40
5.2 APPARATUS 41
5.3 METHOD OF APPLICATION OF THE DRUGS 45
5.4 PROTOCOL AND DOCUMENTATION 47
CHAPTER D: RESULTS
1. KINETICS OF M-CURRENT 56
1.1 ATP ~ 56
1.2 MUSCARINE 57
2. DRUGS TESTED FOR THEIR INTERACTION WITH ATP 59
2.1 THAPSIGARGIN 59
2.2 CHELERYTHRINE 61
2.3 U-73122 (ACTIVE) 63
2.4 U-73343 (INACTIVE) 65
3. SUMMARY OF RESULTS 65
CHAPTER E: DISCUSSION , 67
ABSTRACT 77
CHAPTER
F:
REFERENCES
79
ACKNOWLEDGEMENT 95
ATTACHMENT 97
CURRICULUM VITAE 98
5 |
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| indexdate | 2024-11-22T17:36:59Z |
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| language | English |
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| spelling | Peuckmann, Vera Irina 1975- Verfasser (DE-588)124454577 aut Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) presented by Vera Irina Peuckmann 2002 99 Bl. graph. Darst. : 30 cm txt rdacontent n rdamedia nc rdacarrier Ulm, Univ., Diss., 2003 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010310552&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Peuckmann, Vera Irina 1975- Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) |
| subject_GND | (DE-588)4113937-9 |
| title | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) |
| title_auth | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) |
| title_exact_search | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) |
| title_full | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) presented by Vera Irina Peuckmann |
| title_fullStr | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) presented by Vera Irina Peuckmann |
| title_full_unstemmed | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) presented by Vera Irina Peuckmann |
| title_short | Molecular mechanism of action of the nociception related neurotransmitter adenosine 5'-triphosphate (ATP) |
| title_sort | molecular mechanism of action of the nociception related neurotransmitter adenosine 5 triphosphate atp |
| topic_facet | Hochschulschrift |
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