Molecular mechanism and epochal therapeutics of ischemic stroke and dementia: invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002
Gespeichert in:
| Format: | Tagungsbericht Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier
2003
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | Excerpta medica
International congress series ; 1252 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 506 S. Ill. |
| ISBN: | 0444512225 |
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| 245 | 1 | 0 | |a Molecular mechanism and epochal therapeutics of ischemic stroke and dementia |b invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 |c ed.: Koji Abe |
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| 490 | 1 | |a Excerpta medica : International congress series |v 1252 | |
| 650 | 4 | |a Cerebral ischemia - Molecular aspects | |
| 650 | 4 | |a Cerebral ischemia - Treatment | |
| 650 | 4 | |a Dementia - Molecular aspects | |
| 650 | 4 | |a Dementia - Treatment | |
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| 700 | 1 | |a Abe, Kōji |e Sonstige |4 oth | |
| 711 | 2 | |a International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia |d 2002 |c Okayama |j Sonstige |0 (DE-588)1250010-0 |4 oth | |
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Datensatz im Suchindex
| _version_ | 1804129970338922496 |
|---|---|
| adam_text | vii
Preface v
Acknowledgements v
Contents
Role of intracellular signalling in cerebral ischemia 1
Expression of PTEN and its phosphorylated form after transient middle
cerebral artery occlusion in rat
N. Omori, G. Jin, F. Li, W.R. Zhang, S.J. Wang, Y. Hamakawa, I. Nagano,
Y. Manabe, M. Shoji and K. Abe (Japan) 3
CRE mediated gene expression in cerebral ischemia
K. Kitagawa, T. Mabuchi, S. Sugiura, E. Omura Matsuoka, T. Sasaki,
S. Tanaka, M. Matswnoto and M. Hori (Japan) 13
Poly (ADP ribose) polymerase and brain ischemia
R.J. Traystman, J. Kofler, M. Sawada, L.J. Martin, V.L. Dawson and
P.D. Hum (USA) 21
Effect of angiotensin II on cerebral edema following cerebral ischemia and
reperfusion
N. Hosomi, T. Takahashi and M. Kohno (Japan) 31
Genes and genetic models of cerebral ischemia 43
High density DNA microarray analysis of gene expression following transient
focal cerebral ischemia in mouse
S.T. Hou (Canada), K.G. Becker (USA), A. Baggley, G. Chen and J. Webster
(Canada) 45
viii
Hypoxic induction of vascular endothelial growth factor is impaired in the
spinal cord of the mice with mutant human SOD1 gene
/. Nagano, T. Murakami, M. Shiote, H. Jlieva, Y. Manabe, M. Shoji and K. Abe
(Japan) 57
Early decrease of survival signal protein and DNA repair enzyme in spinal
motor neuron of presymptomatic transgenic mice with a mutant SOD 1 gene
M. Shiote, H. Ilieva, I. Nagano, T. Murakami, T. Hayashi, M. Shoji and K. Abe
(Japan) 65
Alteration in survival signal induction by transient hypoxia in mice expressing
mutant human SOD1 protein
H. Ilieva, I. Nagano, T. Murakami, M. Shiote, M. Shoji and K. Abe (Japan) 73
Renin angiotensin system gene polymorphism in Japanese stroke patients
T. Mizuno, M. Makino, Y. Fujiwara, J. Nagura, K. Shiga, K. Yoshikawa,
K. Nakajima and M. Nakagawa (Japan) 83
Neuroprotection with hypothermia and against inflammation 91
Mild hypothermia enhances efficacy of neuroprotective agents in cerebral
ischemia in rats
T. Kamiya and Y. Katayama (Japan) 93
Effects of aging on hypothermic neuroprotection in acute stroke
H. Naritomi, K. Nagatsuka, K. Miyashita and H. Oe (Japan) 103
The effects of a free radical scavenger, edaravone, combined with mild
hypothermia on ischemic brain damage following transient middle cerebral
artery occlusion in rats
C. Nito, T. Kamiya, S. Amemiya, K. Kato and Y. Katayama (Japan) 109
Immunophilin ameliorates apoptotic neuronal cell death
K. i. Tanaka and N. Ogawa (Japan) 117
Expression of FKBP12 after brain ischemia
H. Kato (Japan) 123
Effects of FK506 on chronic cerebral hypoperfusion induced discrimination
learning disabilities in Wistar rats
K. i. Tanaka, M. Nomura and N. Ogawa (Japan) 129
ix
FK506 facilitates the normalization of post ischemic perturbation of protein
kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors
K. i. Katsura, J. Kurihara, M. Watanabe, K. Takahashi and Y. Katayama
(Japan) 135
Nuclear factor kappa B decoy protects spinal cord injury following ischemia/
reperfusion in rats
M. Nishio, T. Yuguchi, C. Akiyama, T. Fuinaka, M. Taniguchi, Y. Nakajima
and T. Yoshimine (Japan) 141
Functional modulation of astrocytes by a novel agent ONO 2506 mitigates
delayed infarct expansion with a wide therapeutic time window, inducing
prompt neurological recovery through reduction of the extracellular level
of glutamate
T. Asano, N.N. Tateishi, T. Matsui, T. Mori, Y. Kagamiishi, S. Sato and
N. Katsube (Japan) 147
Molecular mechanisms and therapy for ischemic brain damage 153
Caspases and upstream mechanisms in central nervous system ischemic injury
M.A. Moskowitz, D.A. Le and M.J. Whalen (USA) 155
Spatiotemporal changes of free cholesterol and neutral lipids after transient
focal cerebral ischemia in rats
H. Kamada, K. Sato, M. hvai, K. Ohta, W.R. Zhang, 1. Nagano, M. Shoji and
K. Abe (Japan) 163
Apolipoprotein E influences neuronal death and repair
K. Horsburgh, B.W. McColl, F. White and J. McCulloch (UK) 171
Suppression of protein synthesis after transient cerebral ischemia
W. Paschen, T. Mengesdorf and C. Aufenberg (Germany) 179
New vessel formation and expression of angiogenesis related genes in brain
after ischemia
T. Hayashi and P.M. Chan (USA) 193
Therapeutic time window of rt PA on embolic stroke in rat
S. Okubo, H. Igarashi, H. Yamaguchi, K. Arii, M. Sakamaki, G. Mizukoshi,
Y. Aoki and Y. Katayama (Japan) 203
X
Expression of LOX 1 in spontaneously hypertensive rat carotid atherosclerotic
lesions
Y. Hamakawa, N. Omori, K. Sato, I. Nagano, M. Shoji and K. Abe (Japan) 209
Expression of p ERK and cytochrome C signals in rat brain neurons after
transient MCAO
F. Li, N. Omori, K. Sato, G Jin, I. Nagano, Y. Manabe, M. Shoji and K. Abe
(Japan) 213
Protection against ischemic brain damage by GDNF affecting cell survival and
death signals
G. Jin, N. Omori, F. Li, I. Nagano, Y. Manabe, M. Shoji and K. Abe (Japan) 221
Neurotrophic factors and gene therapy for stroke 233
Neuroprotection by drug induced growth factors
Y. Zhu and J. Krieglstein (Germany) 235
Neurotrophic factor delivery by encapsulated cell grafts
/. Date, T. Shingo and T. Ohmoto (Japan) 247
Gene therapy for cerebral arteries
H. Ooboshi and S. Ibayashi (Japan) 253
Therapeutic time window of glial cell line derived neurotrophic factor after
transient middle cerebral artery occlusion in rat
W.R. Zhang, K. Sato, M. Iwai, K. Ota and K. Abe (Japan) 259
Therapeutic time window of Ad GDNF after transient middle cerebral artery
occlusion in rat
W.R. Zhang, K. Sato, M. Iwai, I. Nagano and K. Abe (Japan) 265
Attenuation of neuronal cell death by SOD1 is associated with extracellular
signal regulated kinase after transient focal cerebral ischemia in mice
N. Noshita, T. Hayashi, A. Saito, S. Okuno, T. Sugawara, C. Maier and
P.H. Chan (USA) 275
Adenovirus mediated gene transfer to ischemic brain
J. Takada, Y. Kumai, H. Ooboshi, S. Ibayashi and M. Iida (Japan) 285
xi
The change of distribution and mRNA expression of brain derived
neurotrophic factor after intrastriatal hemorrhage
Y. Kanda, K. Yamada, N. Aihara, H. Hida and H. Nishino (Japan) 291
Imaging of brain function 297
Assessment of neuroreceptor changes in healthy ageing and in Alzheimer s
disease with emission tomography
G.M. Knudsen (Denmark) 299
MR imaging in acute stroke
K. Minematsu (Japan) 309
New MEG technology for evaluating focal brain function
T. Yoshimine, M. Taniguchi, A. Kato (Japan), D. Cheyne and S.E. Robinson
(Canada) 315
Imaging of remote areas after focal cerebral ischemia
A. Tamura, M. Nakane, T. Kuroiwa, T. Nagaoka and K. Sano (Japan) 321
Propagation of recurrent depolarization in the penumbra in the rat—use of in
vivo cortical NADH fluorescence
Y. Takeda, T. Higuchi and K. Morita (Japan) 329
Quantitative aspects of neurovascular interaction
/. Kanno (Japan) 337
Predicting the pathological fate of focal cerebral ischemia using H magnetic
resonance spectroscopic imaging
H. Igarashi (USA, Japan), I.L. Kwee (Japan), S. Okubo (USA), T. Nakada
(Japan) and Y. Katayama (USA) 341
Molecular mechanism of Alzheimer s disease and the therapeutic
potentials 345
Distinct functions of tau isoforms in Alzheimer s disease
H. Mori, S. Kosaka, S. Arawaka and T. Tomiyama (Japan) 347
•y Cleavage and e cleavage of (3 amyloid precursor protein
M. Morishima Kawashima and Y. Ihara (Japan) 355
xii
COX 2 expression in brains of patients with familial Alzheimer s disease
S. Nogawa, M. Takao, S. Suzuki, K. Tanaka, A. Koto, Y. Fukuuchi and
I. Hayakawa (Japan) 363
Accumulation of amyloid (3 protein in Tg2576 mice
T. Kawarabayashi, T. Murakami, E. Matsubara, M. Shoji and K. Abe (Japan) 373
Molecular pathology of transgenic tau mice
T. Murakami, T. Kawarabayashi, E. Matsubara, M. Shoji and K. Abe (Japan) 379
Heat shock proteins reduce aggregation and facilitate degradation of tau
protein
F. Dou, W.J. Netzer (USA), A. Takashima (Japan) and H. Xu (USA) 383
Alzheimer s disease and melatonin
E. Matsubara, M. Shoji, T. Murakami, T. Kawarabayashi and K. Abe (Japan) 395
A/342 vaccine on the Tg2576 Alzheimer model mice
M. Shoji, Y. Harigaya, E. Matsubara, T. Kawarabayashi, T. Murakami,
N. Oomori, K. Sato, I. Nagano and K. Abe (Japan) 399
A/3 vaccination of a genetic model of Alzheimer s disease
H. Hasegawa, C. Janus, J. Pearson, J. McLaurin (Canada), P.M. Mathews,
Y. Jiang, S.D. Schmidt (USA), M.A. Chishti, P. Home, D. Helsin, J. French,
H. T.J. Mount (Canada), R.A. Nixon (USA), M. Mercken (Belgium),
C. Bergeron P.E. Fraser, D. Westaway and P. St. George Hyslop (Canada) 405
Somatosensory evoked fields in Alzheimer s disease
K. lnoue, T. Shirai, A. Hashizume, T. Harada, Y. Kaseda, Y. Mimori,
S. Nakamura and M. Matsumoto (Japan) 411
Activation of stem cell in ischemic brain 417
Highly polysialylated neural cell adhesion molecule positive cells increased
and changed localization in rat hippocampus with exposure to repeated
kindled seizures
K. Sato, M. Iwai, W.R. Zhang, H. Kamada, K. Ohta, I. Nagano, M. Shoji and
K. Abe (Japan) 419
xiii
Activation of neural stem cells after global brain ischemia
M. Iwai, K. Sato, H. Kamada, W.R. Zhang, K. Ohta, N. Omori, I. Nagano,
M. Shoji and K. Abe (Japan) 427
Activation and proliferation of oligodendrocyte progenitor cells after brain
ischemia in the rat
K. Tanaka, S. Nogawa, D. Ito, S. Suzuki, T. Dembo and A. Kosakai (Japan) 435
Cyclooxygenase 2 is involved in increased proliferation of neuronal
progenitor cells in the ischemic mouse hippocampus
T. Sasaki, K. Kitagawa, S. Sugiura, E. Omura Matsuoka, S. Tanaka, Y. Yagita,
H. Okano, M. Matsumoto and M. Hori (Japan) 445
Comparison of proliferation of oligodendrocyte progenitor cells between
young and aged rats after transient cerebral ischemia
K. Ohta, M. Iwai, K. Sato, N. Omori, I. Nagano, M. Shoji and K. Abe (Japan) 451
Stem cell therapy for ischemic brain 459
Differentiation of bone marrow cells in culture and in vivo
M. Miyazaki, K. Kataoka, R.J. Medina, T. Kageyama and N. h. Huh (Japan) 461
Treatment of stroke with marrow stromal cells
M. Chopp and Y. Li (USA) 465
Transplantation of mesenchymal stem cells derived from the bone marrow into
the demyelinated spinal cord
A. Bizen, O. Honmou, M. Inoue, S. Iihoshi, K. Houkin and K. Hashi (Japan) 471
Transplantation of neural stem cells into ischemic brain
O. Honmou (Japan) 477
Cell therapy for cerebral ischemia using vascular endothelial growth factor
secreting cells
T. Shingo, I. Date, A. Yano, K. Kobayashi, A. Takeuchi, T. Yasuhara and
T. Ohmoto (Japan) 483
Transplantation of neural stem cells into epileptic brain
K Matsumoto, A. Sindo, N. Kawai, K. Kunishio, S. Nagao, T. Miyazaki,
T. Itano, Y. Okada, T. Shimazaki and H. Okano (Japan) 489
xiv
Neural stem cells as therapeutic agents for CNS injuries and disorders
H. Okano (Japan) 493
Author index 499
Keyword index 503
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| spelling | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 ed.: Koji Abe 1. ed. Amsterdam Elsevier 2003 XIV, 506 S. Ill. txt rdacontent n rdamedia nc rdacarrier Excerpta medica : International congress series 1252 Cerebral ischemia - Molecular aspects Cerebral ischemia - Treatment Dementia - Molecular aspects Dementia - Treatment Hirnkrankheit (DE-588)4025013-1 gnd rswk-swf Ischämie (DE-588)4162456-7 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2002 Okayama gnd-content Hirnkrankheit (DE-588)4025013-1 s Ischämie (DE-588)4162456-7 s DE-604 Abe, Kōji Sonstige oth International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia 2002 Okayama Sonstige (DE-588)1250010-0 oth Excerpta medica International congress series ; 1252 (DE-604)BV000000592 1252 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010306408&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 Excerpta medica Cerebral ischemia - Molecular aspects Cerebral ischemia - Treatment Dementia - Molecular aspects Dementia - Treatment Hirnkrankheit (DE-588)4025013-1 gnd Ischämie (DE-588)4162456-7 gnd |
| subject_GND | (DE-588)4025013-1 (DE-588)4162456-7 (DE-588)1071861417 |
| title | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 |
| title_auth | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 |
| title_exact_search | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 |
| title_full | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 ed.: Koji Abe |
| title_fullStr | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 ed.: Koji Abe |
| title_full_unstemmed | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 ed.: Koji Abe |
| title_short | Molecular mechanism and epochal therapeutics of ischemic stroke and dementia |
| title_sort | molecular mechanism and epochal therapeutics of ischemic stroke and dementia invited papers from the international symposium on molecular mechanism and epochal therapeutics for ischemic stroke and dementia held in okayama japan 18 to 20 october 2002 |
| title_sub | invited papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia held in Okayama, Japan, 18 to 20 October 2002 |
| topic | Cerebral ischemia - Molecular aspects Cerebral ischemia - Treatment Dementia - Molecular aspects Dementia - Treatment Hirnkrankheit (DE-588)4025013-1 gnd Ischämie (DE-588)4162456-7 gnd |
| topic_facet | Cerebral ischemia - Molecular aspects Cerebral ischemia - Treatment Dementia - Molecular aspects Dementia - Treatment Hirnkrankheit Ischämie Konferenzschrift 2002 Okayama |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010306408&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000000592 |
| work_keys_str_mv | AT abekoji molecularmechanismandepochaltherapeuticsofischemicstrokeanddementiainvitedpapersfromtheinternationalsymposiumonmolecularmechanismandepochaltherapeuticsforischemicstrokeanddementiaheldinokayamajapan18to20october2002 AT internationalsymposiumonmolecularmechanismandepochaltherapeuticsforischemicstrokeanddementiaokayama molecularmechanismandepochaltherapeuticsofischemicstrokeanddementiainvitedpapersfromtheinternationalsymposiumonmolecularmechanismandepochaltherapeuticsforischemicstrokeanddementiaheldinokayamajapan18to20october2002 |