Epigenetics in cancer prevention: early detection and risk assessment
Gespeichert in:
Format: | Buch |
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Sprache: | English |
Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2003
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Schriftenreihe: | Annals of the New York Academy of Sciences
983 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | X, 330 S. Ill., graph. Darst. |
ISBN: | 1573314307 1573314315 |
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adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 983
March 2003
EPIGENETICS IN CANCER
PREVENTION
EARLY DETECTION
AND RISK ASSESSMENT
Editors
Mukesh Verma, Barbara K. Dunn, and Asad Umar
Conference Organizers
Mukesh Verma, Chair
Barbara K. Dunn, Asad Umar, Sharon Ross, Pa wan Jain,
Levy Kopelovich, Wendy Wang, Pothur Srinivas,
and sudhir srivastava
This volume is the result of a conference entitled Epigenetics in Cancer Prevention:
Early Detection and Risk Assessment sponsored by the Division of Cancer Prevention,
National Cancer Institute, National Institutes of Health and held on December 3 4,2001 in
Bethesda, Maryland.
______
Preface: Epigenetics in Cancer Prevention, with Emphasis on Early Detection
and Risk Assessment. By Peter Greenwald and Mukesh Verma ... ix
Epigenetics in Cancer Prevention: Early Detection and Risk Assessment:
Introduction. By Barbara K. Dunn, Mukesh Verma, and Asad Umar 1
Parti. The Basic Mechanism of Epigenetics Mediated Regulation
Chromatin as a Tool for the Study of Genome Function in Cancer. By
FyodorD. Urnov 5
Unanswered Questions about the Role of Promoter Methylation in Carcino
genesis. By Timothy H. Bestor 22
Hypomethylation: One Side of a Larger Picture. By Barbara K. Dunn 28
Genetic and Epigenetic Mosaicism in Cancer Precursor Tissues. By
Benjamin Tycko 43
Epigenetic Control during Lymphoid Development and Immune Responses:
Aberrant Regulation, Viruses, and Cancer. By KATHRIN MUEGGE,
Howard Young, Francis Ruscetti, and Judy Mikovits 55
Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor
Suppressor Genes. 5 PawanK. Jain 71
Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone
Code. By Sam Thiagalingam, Kuang Hung Cheng, Hyunjoo J. Lee,
Nora Mineva, Arunthathi Thiagalingam, and Jose F. Ponte 84
Genome Wide Analysis of Epigenetics in Cancer. By Maxwell P. Lee 101
Part n. Technical Approaches for Analysis
The Development of CpG Island Methylation Biomarkers Using Restriction
Landmark Genomic Scanning. By Dominic J. Smiraglia and
Christoph Plass 110
Sensitive Detection of DNA Methylation. By Susan E. Cottrell and
Peter W. Laird 120
Methylation Sensitive Representational Difference Analysis and Its
Application to Cancer Research. By Atsushi Kaneda, Daiya Takai,
MtCHIO KAMINISHI, ERIKO OKOCm, AND TOSHIKAZU USHUIMA 131
Cancer Biomarker Validation: Standards and Process: Roles for the National
Institute of Standards and Technology (NIST). By Peter E. Barker ... 142
Part HI. Exogenous Factors Affecting Epigenetic Regulation
Epigenetics and the Environment. By Jessica E. Sutherland and
Max Costa 151
Environmental Exposure, DNA Methylation, and Gene Regulation: Lessons
from Diethylstilbesterol Induced Cancers. By Shuanfang Li,
Stephen D. Hursttng, Barbara J. Davis, John A. McLachlan,
and J.Carl Barrett 161
Viral Genes and Methylation. fiy Mukesh Verma 170
Epidemiqlogic Considerations to Assess Altered DNA Methylation from
Environmental Exposures in Cancer. By Lee E. Moore,
Wen Yi Huang, Joyce Chung, and Richard B. Hayes 181
Diet and DNA Methylation Interactions in Cancer Prevention. By
Sharon A. Ross 197
Part IV. Epigenetics, Cancer, and Cancer Prevention
Promoter Hypermethylation as an Epigenetic Component in Type I and Type
U Endometrial Cancers. By JOHN I. RiSlNGER, G. Larry MAXWELL,
Andrew Berchuck, and J. CarlBarrett 208
Epigenetics in Carcinogenesis and Cancer Prevention. By Peter A. JONES 213
Histone Acetylation and Gastrointestinal Carcinogenesis. By Wataru Yasui,
naofflde oue, shigehiro ono, yoshitsugu mltani, reikoito, and
HirofumiNakayama 220
Epigenetics in High Grade Astrocytomas: Opportunities for Prevention and
Detection of Brain Tumors. By Waldemar Debinski, Denise Gibo,
and Aktva Mintz 232
Aberrant DNA Methylation in Ovarian Cancer: Is There an Epigenetic
Predisposition to Drug Response? By Susan H. Wei, Robert Brown,
andTimH. M. Huang 243
DNA Methylation, a Biomarker for Colorectal Cancer: Implications for
Screening and Pathological Utility. By Adrian M. Jubb, Phil Quirke,
and Adam J. Oates 251
Epigenetic Regulation of ARHI in Breast and Ovarian Cancer Cells. By
Yinhua Yu, Satoshi Fujii, Jiuhong Yuan, Robert Z. Luo,
Lin Wang, Jiaju Bao, Mitsutaka Kadota, Mitsuo Oshimura,
Sharon R. Dent, Jean Pierre Issa, and Robert C. Bast, Jr. 268
Epigenetic Changes: Potential Therapeutic Targets. By Thea Kalebic 278
DNA Methylation as a Cancer Specific Biomarker: From Molecules to Popu¬
lations. By Arti Patel, John D. Groopman, and Asad Umar 286
Early Detection and Risk Assessment: Proceedings and Recommendations
from the Workshop on Epigenetics in Cancer Prevention. By
Mukesh Verma, Barbara K. Dunn, Sharon Ross, Pawan Jain,
Wendy Wang, Richard Hayes, and Asad Umar 298
Definitions in Epigenetics. By the Editors 321
Index of Contributors 329
Hie New York Academy of Sciences believes it has a responsibility to provide an open
forum for discussion of scientific questions. The positions taken by the participants in
the reported conferences are their own and not necessarily those of the Academy. The
Academy has no intent to influence legislation by providing such forums.
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series2 | Annals of the New York Academy of Sciences |
spelling | Epigenetics in cancer prevention early detection and risk assessment ed. by Mukesh Verma ... New York, NY New York Acad. of Sciences 2003 X, 330 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 983 Cancer - Aspect génétique - Congrès Cancer - Aspect génétique - Congrès ram Cancer - Facteurs de risque - Congrès Cancer - Facteurs de risque - Congrès ram Cancer - Prévention - Congrès Cancer - Prévention - Congrès ram Genetica gtt Kanker gtt Transformation cellulaire néoplasique - génétique - Actes de congrès Tumeurs - génétique - Actes de congrès Tumeurs - prévention et contrôle - Actes de congrès Cancer Genetic aspects Congresses Cancer Prevention Congresses Cancer Risk factors Congresses Cell Transformation, Neoplastic genetics Congresses Neoplasms genetics Congresses Neoplasms prevention & control Congresses Genregulation (DE-588)4122166-7 gnd rswk-swf Epigenese (DE-588)4152503-6 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf Maligne Transformation (DE-588)4168713-9 gnd rswk-swf Prävention (DE-588)4076308-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2001 Bethesda Md. gnd-content Krebs Medizin (DE-588)4073781-0 s Prävention (DE-588)4076308-0 s Epigenese (DE-588)4152503-6 s DE-604 Genetik (DE-588)4071711-2 s Maligne Transformation (DE-588)4168713-9 s Genregulation (DE-588)4122166-7 s Verma, Mukesh ca. 20./21. Jh. Sonstige (DE-588)124872891 oth Annals of the New York Academy of Sciences 983 (DE-604)BV002532608 983 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010206140&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Epigenetics in cancer prevention early detection and risk assessment Annals of the New York Academy of Sciences Cancer - Aspect génétique - Congrès Cancer - Aspect génétique - Congrès ram Cancer - Facteurs de risque - Congrès Cancer - Facteurs de risque - Congrès ram Cancer - Prévention - Congrès Cancer - Prévention - Congrès ram Genetica gtt Kanker gtt Transformation cellulaire néoplasique - génétique - Actes de congrès Tumeurs - génétique - Actes de congrès Tumeurs - prévention et contrôle - Actes de congrès Cancer Genetic aspects Congresses Cancer Prevention Congresses Cancer Risk factors Congresses Cell Transformation, Neoplastic genetics Congresses Neoplasms genetics Congresses Neoplasms prevention & control Congresses Genregulation (DE-588)4122166-7 gnd Epigenese (DE-588)4152503-6 gnd Krebs Medizin (DE-588)4073781-0 gnd Genetik (DE-588)4071711-2 gnd Maligne Transformation (DE-588)4168713-9 gnd Prävention (DE-588)4076308-0 gnd |
subject_GND | (DE-588)4122166-7 (DE-588)4152503-6 (DE-588)4073781-0 (DE-588)4071711-2 (DE-588)4168713-9 (DE-588)4076308-0 (DE-588)1071861417 |
title | Epigenetics in cancer prevention early detection and risk assessment |
title_auth | Epigenetics in cancer prevention early detection and risk assessment |
title_exact_search | Epigenetics in cancer prevention early detection and risk assessment |
title_full | Epigenetics in cancer prevention early detection and risk assessment ed. by Mukesh Verma ... |
title_fullStr | Epigenetics in cancer prevention early detection and risk assessment ed. by Mukesh Verma ... |
title_full_unstemmed | Epigenetics in cancer prevention early detection and risk assessment ed. by Mukesh Verma ... |
title_short | Epigenetics in cancer prevention |
title_sort | epigenetics in cancer prevention early detection and risk assessment |
title_sub | early detection and risk assessment |
topic | Cancer - Aspect génétique - Congrès Cancer - Aspect génétique - Congrès ram Cancer - Facteurs de risque - Congrès Cancer - Facteurs de risque - Congrès ram Cancer - Prévention - Congrès Cancer - Prévention - Congrès ram Genetica gtt Kanker gtt Transformation cellulaire néoplasique - génétique - Actes de congrès Tumeurs - génétique - Actes de congrès Tumeurs - prévention et contrôle - Actes de congrès Cancer Genetic aspects Congresses Cancer Prevention Congresses Cancer Risk factors Congresses Cell Transformation, Neoplastic genetics Congresses Neoplasms genetics Congresses Neoplasms prevention & control Congresses Genregulation (DE-588)4122166-7 gnd Epigenese (DE-588)4152503-6 gnd Krebs Medizin (DE-588)4073781-0 gnd Genetik (DE-588)4071711-2 gnd Maligne Transformation (DE-588)4168713-9 gnd Prävention (DE-588)4076308-0 gnd |
topic_facet | Cancer - Aspect génétique - Congrès Cancer - Facteurs de risque - Congrès Cancer - Prévention - Congrès Genetica Kanker Transformation cellulaire néoplasique - génétique - Actes de congrès Tumeurs - génétique - Actes de congrès Tumeurs - prévention et contrôle - Actes de congrès Cancer Genetic aspects Congresses Cancer Prevention Congresses Cancer Risk factors Congresses Cell Transformation, Neoplastic genetics Congresses Neoplasms genetics Congresses Neoplasms prevention & control Congresses Genregulation Epigenese Krebs Medizin Genetik Maligne Transformation Prävention Konferenzschrift 2001 Bethesda Md. |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010206140&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV002532608 |
work_keys_str_mv | AT vermamukesh epigeneticsincancerpreventionearlydetectionandriskassessment |