Treating alcohol and drug abuse: an evidence based review
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Weinheim
Wiley-VCH
2003
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 631 S. graph. Darst. 1 CD-ROM (12 cm) |
| ISBN: | 352730682X |
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| adam_text | XI
Contents
Preface V
Foreword IX
1 Intervention against Hazardous Alcohol Consumption
Secondary Prevention of Alcohol Problems 1
1.1 Introduction 1
1.2 Aim 2
1.3 Methods 2
1.3.1 Selection of Studies, Inclusion and Exclusion Criteria 2
1.3.2 Search Strategy 2
1.3.3 Outcome Measures 3
1.3.4 Raring Scientific Quality 3
1.3.5 Analyzing the Results 3
1.4 Results 4
1.4.1 Literature Search 4
1.4.2 Previous Reviews and Meta Analysis 4
1.4.3 Randomized and Controlled Studies 5
1.4.4 Studies with Positive Outcome (Measures) Presented in Order
of Quality 16
1.4.5 Studies without Significant Effects, Presented in Order of Quality 23
1.5 Analysis of the Overall Results of the Reviewed Studies 26
1.5.1 Studies with a Positive Outcome 26
1.5.2 Studies which Showed No Effects 36
1.6 Important Aspects of Brief Intervention 36
1.6.1 Analysis of Special Groups 36
1.7 Problems with Dropout in Studies 37
1.8 Problems with Implementation 37
1.9 Summary 38
Glossary 38
References 39
XII I Contents
2 Psychosocial Treatment for Alcohol Dependence 43
2.1 Introduction 43
2.1.1 Earlier Reviews 43
2.1.2 Assessing the Effects of Different Methods 43
2.1.3 Methodological Deficiencies and Problems 45
2.1.4 Treatment Methods 45
2.1.5 Treatment Effects 47
2.1.6 Questions Addressed 48
2.1.7 Intensity and Aftercare 49
2.1.8 Subgroups of Alcohol Dependence 49
2.2 Method and Material 50
2.2.1 Search Strategies 50
2.2.2 Result Protocol 50
2.2.3 Meta analysis 51
2.3 Results 51
2.3.1 Does psychosocial treatment have any effect?
Comparisons with no treatment 52
2.3.2 Are some methods superior to others? 54
2.4 Motivational Methodology 54
2.5 Methods Specifically Aimed at Changing the Drinking Problem Itself 56
2.5.1 Cognitive Behavioral Therapy (CBT) 56
2.5.2 Broad Spectrum Treatment with CBT Focus 57
2.5.3 CRA Treatment Community Reinforcement Approach 59
2.5.4 Self control Training 61
2.5.5 Cue Exposure 62
2.5.6 Other 63
2.5.7 Twelve Step Treatment 63
2.6 Methods Aimed at the Factors Behind Alcohol Dependence 65
2.6.1 Dynamically Oriented Treatments 65
2.7 Standard Treatment 67
2.8 Marital Therapies and Interventions Focused on Family Members 69
2.9 Studies Showing Matching Results 70
2.10 Comparing the Intensity of Treatment and Aftercare 73
2.11 Subgroups of Alcohol Dependent Patients 75
2.12 Therapist Factors 78
2.13 Gender related Effects 79
2.14 Renewed Literature Search 82
References 178
3 Pharmacotherapy for Alcohol Withdrawal Syndrome 189
3.1 Introduction 189
3.2 Methods 190
3.2.1 Selection Criteria 190
3.2.2 Diagnostic Criteria and Outcome Measures 290
3.2.3 Search Strategy 190
Contents I XIII
3.2.4 Results 191
3.3 Included Studies 191
3.3.1 Treatment of Alcohol Withdrawal 191
3.3.1.1 Benzodiazepines 191
3.3.1.2 Chlormethiazole and Anti Epileptics 204
3.3.1.3 Imidazoline Agonists 214
3.3.1.4 Beta Receptor Antagonists 220
3.3.1.5 Nitrous Oxide 221
3.3.1.6 Thiamine 221
3.3.1.7 Psychological Treatment 228
3.3.1.8 Other Treatment 228
3.3.1.9 Meta analyses and Reviews 229
3.3.2 Treatment of Delirium Tremens 229
3.3.2.1 Barbiturates 229
3.3.2.2 Benzodiazepines 234
3.3.2.3 Chlormethiazole 234
3.3.2.4 Imidazoline Agonists 234
3.3.2.5 Other Treatment 235
3.3.2.6 Meta analyses 235
3.4 Discussion 235
3.5 Summary 239
References 240
4 Pharmacotherapy for Alcohol Dependence 247
4.1 Introduction 247
4.2 Methods 248
4.2.1 Search Strategies 248
4.2.2 Complementary Search 248
4.2.3 Unpublished Studies 249
4.3 Analytical Principles 249
4.3.1 Categorization 249
4.3.2 Target Group and Treatment Goals 249
AA Overview of Tables 250
4.5 Overview of Included Studies 252
4.6 Results 252
4.6.1 Aversive Agents 252
4.6.2 Antipsychotic Drugs 260
4.6.3 Dopamine Agonists 260
4.6.4 SSRI Agents 262
4.6.5 Other Agents with Effect on the 5 HT System 268
4.6.6 Acamprosate 268
4.6.7 Naltrexone and Nalmefene 269
4.6.8 Other Agents 289
4.6.9 Lithium 289
4.7 Comorbidity 294
XIV I Contents
4.7.1 Anti Depressive Treatment and Psychiatric Comorbidity (Depression) 294
4.8 Discussion 295
4.8.1 Acamprosate and Naltrexone 295
4.8.2 Aversive Agents 295
4.8.3 Other Agents 302
4.8.4 Treatment of Comorbid Conditions 302
4.9 Conclusions 302
Reference 303
5 The Long Term Course in Alcohol and Drug Dependence 313
5.1 Introduction 313
5.2 Methods 314
5.2.1 Search Strategies 314
5.2.2 Inclusion Criteria 314
5.2.3 Search Results 314
5.3 Epidemiological Studies 315
5.4 Longitudinal Clinical Trials 317
5.4.1 Long Term Course in Alcohol Dependence 317
5.5 Long Term Course in Heroin Dependence 319
5.6 Alcohol and Drug Abuse as a Chronic Condition 321
5.7 Conclusions 322
References 323
6 Psychosocial Treatment for Drug Dependence 325
6.1 Introduction 325
6.2 Psychosocial Methods a Review 326
6.2.1 Supportive Treatment Methods 326
6.2.1.1 Institutional Treatment 327
6.2.1.2 Structure Enhancing Interventions 328
6.2.1.3 Other Supportive Intervention and Treatment Methods 328
6.2.2 Re educative Methods 329
6.2.3 More Extensive Psychotherapy 331
6.2.4 Reconstructive Therapy 333
6.3 Research Considerations 335
6.3.1 Observational Studies 335
6.3.2 Questions 335
6.3.3 Theoretical Approach 335
6.4 Methods 336
6.4.1 Search Strategies 336
6.4.2 Representative 336
6.4.3 Publication Bias 337
6.4.4 Quality Rating 338
6.4.5 Classifying and Synthesizing the Material 338
6.4.6 Data Analysis 339
6.5 Results 340
Contents I XV
6.5.1 Meta analysis of Treatment for Opiate Dependence 340
6.5.1.1 Reduction of Heroin Abuse 341
6.5.1.2 Retention in Opiate Studies 344
6.5.1.3 Conclusions 344
6.5.2 Meta analysis of Interventions in Cocaine Dependence 344
6.5.2.1 Reduction of Cocaine Abuse 345
6.5.2.2 Retention in Cocaine Studies 350
6.5.2.3 Conclusions 352
6.5.3 Limitations in Interpreting the Results of Meta analyses 351
6.5.3.1 Combination Therapy with Antidepressants and Cognitive Therapy
in Cocaine Dependence 352
6.5.3.2 Meta analysis of Interventions in Cannabis Dependence 354
6.5.3.3 Conclusions 354
6.5.4 Randomized Studies of Institutional Treatment 355
6.5.4.1 Meta analysis of Institutional Treatment with Opiate Abuse
as Outcome Measure 355
6.5.4.2 Meta analysis of Institutional Treatment with Reduced Opiate
and Cocaine Abuse as Outcome Measure 355
6.5.4.3 Retention in Institutional Treatment 358
6.5.4.4 Conclusion 359
6.5.5 Structure enhancing Interventions 359
6.5.5.1 Treating Mentally 111 and Homeless Abusers 362
6.5.5.2 Conclusions 363
6.5.6 Before and After Changes in Treatment 363
6.5.6.1 Studies of Opiate Abuse 363
6.5.6.2 Studies of Cocaine Abuse 363
6.5.6.3 Studies of Institutional Treatment 368
6.5.6.4 Conclusions 368
6.5.7 Effects on Factors other than Abuse 369
6.5.7.1 Treatment Focus 369
6.5.7.2 Limitations of Randomized Treatment Studies 369
6.6 Appendix 369
References 404
7 Pharmacotherapy for Opioid Withdrawal 425
7.1 Background 425
7.2 Principles of Withdrawal Treatment 426
7.3 Non Rapid 427
7.3.1 Adrenergic Agonists Clonidine (unless otherwise stated) versus 427
7.3.1.1 Placebo 427
7.3.1.2 Methadone 427
7.3.1.3 Bubrenorphine 428
7.3.1.4 Doxepin 428
7.3.1.5 Other Adrenergic Agonists 428
7.3.2 Opioid Agonists Methadone versus 420
XVI I Contents
7.3.2.1 Placebo 420
7.3.2.2 Bubrenorphine 420
7.3.2.3 Propoxyphene 420
7.3.2.4 Chlordiazepoxide 420
7.3.2.5 Summary (Non Rapid) 421
7.4 Rapid 438
7A.I Adrenergic Agonist + Opioid Antagonists Clonidine versus Clonidine +
naltrexone/naloxone versus 438
7.4.1.1 Placebo 438
7.4.1.2 Buprenorphine 438
7.4.1.3 Methadone 438
7.4.2 Partial opioid agonist + opioid antagonist + adrenergic agonist 439
7.4.2.1 Summary (Rapid) 439
7.5 Ultra Rapid (Adrenergic agonist) + opioid antagonist under anesthesia,
or under different levels of sedation 448
7.5.1 Naloxone versus Placebo 449
7.5.2 (Clonidine) + Naloxone/Naltrexone under Light Sedation
versus Deep Sedation 448
7.5.3 Summary (Ultra Rapid) 448
7.6 Reviews 449
7.7 Conclusion 452
Reference 453
7.8 Appendix 455
7.8.1 Non Rapid 455
7.8.1.1 Adrenergic Agonists 455
7.8.1.2 Opioid agonists 458
7.8.1.3 Dopamine agonists 458
7.8.2 Rapid Adrenergic agonist + opioid antagonists 458
7.8.3 Ultra Rapid (Adrenergic agonists) + opioid antagonists under
anesthesia 460
7.8.4 Reviews 462
7.8.5 Conclusion 462
Appendix References 463
8 Pharmacotherapy for Opioid Dependence 465
8.1 Background 465
8.2 Agonists 467
8.2.1 Agonists (Including Partial) Versus Control 467
8.2.2 Agonists versus Other Agonists 469
8.2.3 Agonists versus Antagonists 472
8.2.4 Agonists versus the Same Agonists 472
8.2.4.1 Distribution Studies 472
8.2.4.2 Dose Level Studies 473
8.3 Antagonists 498
8.3.1 Antagonists versus Control 498
Contents I XVII
8.3.2 Antagonists versus the Same Antagonists 499
8.3.2.1 Distribution Studies 499
8.4 Adjunctive Treatment with Antidepressants for Depressive Disorders 506
8.4.1 Antidepressants versus Control 506
8.5 Meta Analysis 506
8.6 Reviews 512
8.7 Conclusion 512
8.7.1 Agonists, Including Partial 512
8.7.2 Antagonists 523
8.7.3 Antidepressants 513
8.7.4 Other Illegal Drugs 513
References 524
8.8 Appendix 529
8.8.1 Agonists 529
8.8.1.1 Agonists (Including Partial) versus Control 529
8.8.1.2 Agonists versus Other Agonists 529
8.8.1.3 Agonists versus the Same Agonists 529
8.8.2 Antagonists 526
8.8.2.1 Antagonists versus Control 526
8.8.2.2 Antagonists versus the Same Antagonists 528
8.8.2.3 Meta Analysis 528
8.8.2.4 Conclusion 529
Appendix References 530
9 Pharmacotherapy for Cocaine Dependence 533
9.1 Background and Pharmacological Principles 533
9.2 Long term Pharmacotherapy in Cocaine Dependence 535
9.2.1 Antidepressants 535
9.2.1.1 Tricyclic antidepressants 535
9.2.1.2 SSRI 536
9.2.1.3 Other antidepressants 536
9.2.1.4 Meta analysis 537
9.2.2 Dopamine Agonists 538
9.2.3 Other Dopamine Agonists 538
9.2.4 Antiepileptics 539
9.3 Withdrawal Treatment in Cocaine Dependence 542
9.3.1 Dopamine Agonist 542
9.3.2 Partial Serotonin Agonist 542
9.4 Interaction Studies 554
9.4.1 Antidepressants 554
9.4.2 Dopamine Agonists 554
9.4.3 Antiepileptics 554
9.4.4 Partial Opioid Agonist 554
9.5 Review Articles 554
9.6 Long term Pharmacotherapy in Methamphetamine Dependence 554
XVIII I Contents
9.6.1 Antidepressants 555
9.6.1.1 Tricydic Antidepressants 555
9.7 Conclusions 555
9.7.1 Long term Pharmacological Treatment in Cocaine Dependence 555
9.7.2 Withdrawal Treatment in Cocaine Dependence 558
9.7.3 Interactions 558
9.7.4 Long term Pharmacological Treatment in Methamphetamine
Dependence 558
References 559
9.8 Appendix 562
9.8.1 Long term Pharmacotherapy in Cocaine Dependence 563
9.8.1.1 Antidepressants 563
9.8.1.2 Dopamine Agonists 563
9.8.1.3 Antiepileptics 563
9.8.1.4 Disulfiram 563
9.8.1.5 Neuroleptics 570
9.8.1.6 Serotonin Antagonists 570
9.8.1.7 Opioid Antagonist 570
9.8.1.8 Stimulants 570
9.8.1.9 P Blockers 570
Appendix References 571
10 Pregnancy, Neonatal Period, and Substance Abuse 573
10.1 Introduction 573
10.1.1 Aim 573
10.2 Search Strategy and Methods 574
10.3 Incidence and Prevalence of Alcohol and Drug Use
in Pregnant Women 574
10.4 Treatment Research Alcohol and Pregnancy 575
10.5 Narcotics and Pregnancy 576
10.5.1 Cannabis and Pregnancy 577
10.5.2 Amphetamine, Other Central Stimulants, and Pregnancy 577
10.5.3 Cocaine and Pregnancy 577
10.5.4 Opiates and Pregnancy 578
10.5.5 Benzodiazepines and Pregnancy 578
10.5.6 Other Narcotics and Pregnancy 578
10.6 Studies of the Treatment of Drug Abuse in Pregnancy 578
10.7 Staff Training 579
10.8 Summary 579
References 581
Contents I XIX
Appendix
Appendix 1. Project Group Authors and Scientific Reviewers 583
Appendix 2. Quality Checklist 585
Appendix 3. Guidelines for Estimating Effect Size 586
Appendix 4. Glossary 587
Conclusions by SBU 595
SBU Summary 599
Index 611
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV016450000 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:10:38Z |
| institution | BVB |
| isbn | 352730682X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010171475 |
| oclc_num | 249129564 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-20 DE-29 DE-M49 DE-BY-TUM DE-11 |
| owner_facet | DE-355 DE-BY-UBR DE-20 DE-29 DE-M49 DE-BY-TUM DE-11 |
| physical | XIX, 631 S. graph. Darst. 1 CD-ROM (12 cm) |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | Wiley-VCH |
| record_format | marc |
| spelling | Treating alcohol and drug abuse an evidence based review ed. by Mats Berglund ... Weinheim Wiley-VCH 2003 XIX, 631 S. graph. Darst. 1 CD-ROM (12 cm) txt rdacontent n rdamedia nc rdacarrier Alkoholismus - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Alkoholismus - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Cocain - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Opiate - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Evidenz-basierte Medizin (DE-588)4543414-1 gnd rswk-swf Cocain (DE-588)4128249-8 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Alkoholismus (DE-588)4001220-7 gnd rswk-swf Drogenabhängigkeit (DE-588)4138597-4 gnd rswk-swf Opiate (DE-588)4075669-5 gnd rswk-swf Psychotherapie (DE-588)4047746-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Alkoholismus (DE-588)4001220-7 s Psychotherapie (DE-588)4047746-0 s Evidenz-basierte Medizin (DE-588)4543414-1 s DE-604 Pharmakotherapie (DE-588)4076066-2 s Drogenabhängigkeit (DE-588)4138597-4 s Opiate (DE-588)4075669-5 s Cocain (DE-588)4128249-8 s Berglund, Mats Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010171475&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Treating alcohol and drug abuse an evidence based review Alkoholismus - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Alkoholismus - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Cocain - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Opiate - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Evidenz-basierte Medizin (DE-588)4543414-1 gnd Cocain (DE-588)4128249-8 gnd Pharmakotherapie (DE-588)4076066-2 gnd Alkoholismus (DE-588)4001220-7 gnd Drogenabhängigkeit (DE-588)4138597-4 gnd Opiate (DE-588)4075669-5 gnd Psychotherapie (DE-588)4047746-0 gnd |
| subject_GND | (DE-588)4543414-1 (DE-588)4128249-8 (DE-588)4076066-2 (DE-588)4001220-7 (DE-588)4138597-4 (DE-588)4075669-5 (DE-588)4047746-0 (DE-588)4143413-4 |
| title | Treating alcohol and drug abuse an evidence based review |
| title_auth | Treating alcohol and drug abuse an evidence based review |
| title_exact_search | Treating alcohol and drug abuse an evidence based review |
| title_full | Treating alcohol and drug abuse an evidence based review ed. by Mats Berglund ... |
| title_fullStr | Treating alcohol and drug abuse an evidence based review ed. by Mats Berglund ... |
| title_full_unstemmed | Treating alcohol and drug abuse an evidence based review ed. by Mats Berglund ... |
| title_short | Treating alcohol and drug abuse |
| title_sort | treating alcohol and drug abuse an evidence based review |
| title_sub | an evidence based review |
| topic | Alkoholismus - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Alkoholismus - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Cocain - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Opiate - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Evidenz-basierte Medizin (DE-588)4543414-1 gnd Cocain (DE-588)4128249-8 gnd Pharmakotherapie (DE-588)4076066-2 gnd Alkoholismus (DE-588)4001220-7 gnd Drogenabhängigkeit (DE-588)4138597-4 gnd Opiate (DE-588)4075669-5 gnd Psychotherapie (DE-588)4047746-0 gnd |
| topic_facet | Alkoholismus - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Alkoholismus - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Cocain - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Opiate - Pharmakotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Drogenabhängigkeit - Psychotherapie - Evidenz-basierte Medizin - Aufsatzsammlung Evidenz-basierte Medizin Cocain Pharmakotherapie Alkoholismus Drogenabhängigkeit Opiate Psychotherapie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010171475&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT berglundmats treatingalcoholanddrugabuseanevidencebasedreview |