Holdings: Plant protease inhibitors

Plant protease inhibitors: significance in nutrition, plant protection, cancer prevention and genetic engineering

"Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It d...

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Bibliographic Details
Main Author:	Birk, Yehudith (Author)
Format:	Book
Language:	English
Published:	Berlin ; Heidelberg ; New York ; Hong Kong ; London ; Milan ; Pa Springer 2003
Subjects:	Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts > therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen Proteaseinhibitor
Online Access:	Inhaltsverzeichnis
Summary:	"Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It deals with their inhibitory effects on insects and pathogens with their induction and introduction into plants by genetic engineering for plant protection. The induced resistance of insects to the inhibitors and the hazards to friendly insects are also discussed. Futher, findings are presented on the cancer chemopreventive properties of the inhibitors at the cellular, tissue and organ levels and in the organism."--BOOK JACKET.
Item Description:	Literaturverz. S. 129 - 164
Physical Description:	XI, 170 S. Ill., graph. Darst. : 24 cm
ISBN:	3540001182

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adam_text	CONTENTS 1 INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2 DEFINITIONS AND GENERAL CHARACTERISTICS: EARLY FINDINGS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.1 THE REACTIVE SITE . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.2 THE STANDARD MECHANISM . . . . . . . . . . . . . . . . . . . . 7 3 INHIBITOR FAMILIES OF PLANT ORIGIN: CLASSIFICATION AND CHARACTERIZATION . . . . . . . . . . . 11 3.1 KUNITZ SOYBEAN TRYPSIN INHIBITOR FAMILY . . . . . . . 12 3.1.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.1.2 INHIBITORY ACTIVITY AND SPECIFICITY OF INHIBITION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.1.3 CONTENT, FORMATION, AND DEGRADATION IN THE SEED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.1.4 GENE EXPRESSION . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 3.1.5 KUNITZ SOYBEAN TRYPSIN INHIBITOR-LIKE INHIBITORS FROM OTHER SOURCES . . . . . . . . . . . . . . . . 16 3.1.5.1 ERYTHRINA SEEDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 3.1.5.2 MISCELLANEOUS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 3.2 BOWMAN-BIRK PROTEASE INHIBITOR FAMILY . . . . . . . . 23 3.2.1 BOWMAN-BIRK PROTEASE INHIBITOR FROM SOYBEANS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 3.2.1.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 3.2.1.2 STRUCTURE, MODIFICATIONS, AND STABILITY . . . . . . . . . . 25 CONTENTS X 3.2.1.3 SYNTHESIS, GENES, AND GENES EXPRESSION . . . . . . . . 31 3.2.2 BOWMAN-BIRK PROTEASE INHIBITORS FROM OTHER LEGUME SEEDS . . . . . . . . . . . . . . . . . . . 33 3.2.2.1 FROM PEANUTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3.2.2.2 FROM PEAS AND BEANS . . . . . . . . . . . . . . . . . . . . . . . 36 3.2.2.3 FROM MISCELLANEOUS LEGUME SEEDS . . . . . . . . . . . . 3 9 3.2.3 BOWMAN-BIRK PROTEASE INHIBITORS FROM OTHER SOURCES . . . . . . . . . . . . . . . . . . . . . . . . 44 3.3 POTATO INHIBITOR FAMILIES . . . . . . . . . . . . . . . . . . . . 46 3.3.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 3.3.2 POTATO I INHIBITOR FAMILY . . . . . . . . . . . . . . . . . . . . 46 3.3.3 POTATO II INHIBITOR FAMILY . . . . . . . . . . . . . . . . . . . . 47 3.3.4 OTHER POLYPEPTIDE INHIBITORS OF SERINE PROTEASES . . . . . . . . . . . . . . . . . . . . . . . . . 48 3.3.5 CARBOXYPEPTIDASE INHIBITOR . . . . . . . . . . . . . . . . . . 49 3.4 SQUASH INHIBITOR FAMILY . . . . . . . . . . . . . . . . . . . . . 51 3.4.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 3.4.2 ISOLATION AND CHARACTERIZATION . . . . . . . . . . . . . . . . 52 3.4.3 STRUCTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 3.4.4 SYNTHESIS, GENES AND GENES EXPRESSION . . . . . . . . . 56 3.5 BARLEY TRYPSIN INHIBITOR FAMILY . . . . . . . . . . . . . . . 59 3.6 MISCELLANEOUS INHIBITORS OF SERINE PROTEASES. . . . . 60 3.7 CYSTATINS (CYSTEINE PROTEASE INHIBITORS) OF PLANT ORIGIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 3.8 OTHER SPECIFICITIES OF INHIBITION . . . . . . . . . . . . . . . 70 4 PLANT PROTEASE INHIBITORS IN NUTRITION . . . . . . . . . 75 4.1 EARLY OBSERVATIONS . . . . . . . . . . . . . . . . . . . . . . . . . 75 4.2 EFFECT ON GROWTH AND ON THE PANCREAS . . . . . . . . . . 77 4.3 LONG-TERM FEEDING EFFECTS AND RELEVANCE TO HUMANS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 4.4 LATER NUTRITIONAL STUDIES . . . . . . . . . . . . . . . . . . . . 81 4.5 CONCLUDING REMARKS. . . . . . . . . . . . . . . . . . . . . . . . 84 5 PLANT PROTEASE INHIBITORS AND PLANT PROTECTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 5.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 CONTENTS XI 5.2 EFFECT OF PLANT PROTEASE INHIBITORS ON THE DEVELOPMENT OF INSECTS . . . . . . . . . . . . . . . . 86 5.3 INDUCTION OF PLANT PROTEASE INHIBITORS IN PLANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 5.4 INTRODUCTION OF PLANT PROTEASE INHIBITORS INTO PLANTS BY GENETIC ENGINEERING . . . . . . . . . . . . 98 5.5 INDUCED RESISTANCE OF INSECTS TO PLANT PROTEASE INHIBITORS . . . . . . . . . . . . . . . . . 105 5.6 ANTIFUNGAL PLANT PROTEASE INHIBITORS . . . . . . . . . . 109 6 PLANT PROTEASE INHIBITORS AS CANCER CHEMOPREVENTIVE AGENTS . . . . . . . . . . . . . . . . . . . 111 6.1 INTRODUCTORY REMARKS. . . . . . . . . . . . . . . . . . . . . . 111 6.2 AT THE CELLULAR, TISSUE, AND ORGAN LEVELS . . . . . . . 112 6.3 IN THE ORGANISM . . . . . . . . . . . . . . . . . . . . . . . . . . 116 6.4 PROPOSED MECHANISMS OF ANTICARCINOGENESIS OF PROTEASE INHIBITORS . . . . . . . . . . . . . . . . . . . . . . 120 7 OTHER ACTIVITIES OF PLANT PROTEASE INHIBITORS . . . 123 7.1 INTERACTION WITH PLANT PROTEASES . . . . . . . . . . . . . . 123 7.2 PLANT PROTEASE INHIBITORS AS ALLERGENS . . . . . . . . . 125 7.3 PLANT PROTEASE INHIBITORS AND PROGRAMMED CELL DEATH IN PLANTS. . . . . . . . . . . . . . . . . . . . . . . . 126 REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 SUBJECT INDEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
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author	Birk, Yehudith
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spelling	Birk, Yehudith Verfasser aut Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk Berlin ; Heidelberg ; New York ; Hong Kong ; London ; Milan ; Pa Springer 2003 XI, 170 S. Ill., graph. Darst. : 24 cm txt rdacontent n rdamedia nc rdacarrier Literaturverz. S. 129 - 164 "Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It deals with their inhibitory effects on insects and pathogens with their induction and introduction into plants by genetic engineering for plant protection. The induced resistance of insects to the inhibitors and the hazards to friendly insects are also discussed. Futher, findings are presented on the cancer chemopreventive properties of the inhibitors at the cellular, tissue and organ levels and in the organism."--BOOK JACKET. Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd rswk-swf Proteaseinhibitor (DE-588)4130450-0 gnd rswk-swf Pflanzen (DE-588)4045539-7 s Proteaseinhibitor (DE-588)4130450-0 s DE-604 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010121313&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Birk, Yehudith Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd Proteaseinhibitor (DE-588)4130450-0 gnd
subject_GND	(DE-588)4045539-7 (DE-588)4130450-0
title	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering
title_auth	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering
title_exact_search	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering
title_full	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk
title_fullStr	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk
title_full_unstemmed	Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk
title_short	Plant protease inhibitors
title_sort	plant protease inhibitors significance in nutrition plant protection cancer prevention and genetic engineering
title_sub	significance in nutrition, plant protection, cancer prevention and genetic engineering
topic	Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd Proteaseinhibitor (DE-588)4130450-0 gnd
topic_facet	Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen Proteaseinhibitor
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010121313&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT birkyehudith plantproteaseinhibitorssignificanceinnutritionplantprotectioncancerpreventionandgeneticengineering

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