Plant protease inhibitors: significance in nutrition, plant protection, cancer prevention and genetic engineering
"Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It d...
Gespeichert in:
1. Verfasser: | |
---|---|
Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Berlin ; Heidelberg ; New York ; Hong Kong ; London ; Milan ; Pa
Springer
2003
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Zusammenfassung: | "Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It deals with their inhibitory effects on insects and pathogens with their induction and introduction into plants by genetic engineering for plant protection. The induced resistance of insects to the inhibitors and the hazards to friendly insects are also discussed. Futher, findings are presented on the cancer chemopreventive properties of the inhibitors at the cellular, tissue and organ levels and in the organism."--BOOK JACKET. |
Beschreibung: | Literaturverz. S. 129 - 164 |
Beschreibung: | XI, 170 S. Ill., graph. Darst. : 24 cm |
ISBN: | 3540001182 |
Internformat
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264 | 1 | |a Berlin ; Heidelberg ; New York ; Hong Kong ; London ; Milan ; Pa |b Springer |c 2003 | |
300 | |a XI, 170 S. |b Ill., graph. Darst. : 24 cm | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
500 | |a Literaturverz. S. 129 - 164 | ||
520 | 1 | |a "Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It deals with their inhibitory effects on insects and pathogens with their induction and introduction into plants by genetic engineering for plant protection. The induced resistance of insects to the inhibitors and the hazards to friendly insects are also discussed. Futher, findings are presented on the cancer chemopreventive properties of the inhibitors at the cellular, tissue and organ levels and in the organism."--BOOK JACKET. | |
650 | 4 | |a Antineoplastic Agents | |
650 | 4 | |a Pest Control, Biological | |
650 | 4 | |a Phytochemicals | |
650 | 4 | |a Plant Extracts |x therapeutic use | |
650 | 4 | |a Plant Proteins | |
650 | 4 | |a Protease Inhibitors | |
650 | 4 | |a Protease inhibitors | |
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Datensatz im Suchindex
_version_ | 1804129716889714688 |
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adam_text | CONTENTS 1 INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . 1 2 DEFINITIONS AND GENERAL CHARACTERISTICS: EARLY FINDINGS
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.1 THE
REACTIVE SITE . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
2.2 THE STANDARD MECHANISM . . . . . . . . . . . . . . . . . . . . 7 3
INHIBITOR FAMILIES OF PLANT ORIGIN: CLASSIFICATION AND CHARACTERIZATION
. . . . . . . . . . . 11 3.1 KUNITZ SOYBEAN TRYPSIN INHIBITOR FAMILY . .
. . . . . 12 3.1.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . 12 3.1.2 INHIBITORY ACTIVITY AND SPECIFICITY OF
INHIBITION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
14 3.1.3 CONTENT, FORMATION, AND DEGRADATION IN THE SEED . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . 14 3.1.4 GENE EXPRESSION .
. . . . . . . . . . . . . . . . . . . . . . . . . . 15 3.1.5 KUNITZ
SOYBEAN TRYPSIN INHIBITOR-LIKE INHIBITORS FROM OTHER SOURCES . . . . . .
. . . . . . . . . . 16 3.1.5.1 ERYTHRINA SEEDS . . . . . . . . . . . . .
. . . . . . . . . . . . . . . 16 3.1.5.2 MISCELLANEOUS . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . 19 3.2 BOWMAN-BIRK PROTEASE
INHIBITOR FAMILY . . . . . . . . 23 3.2.1 BOWMAN-BIRK PROTEASE INHIBITOR
FROM SOYBEANS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
3.2.1.1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . 23 3.2.1.2 STRUCTURE, MODIFICATIONS, AND STABILITY . . . . .
. . . . . 25 CONTENTS X 3.2.1.3 SYNTHESIS, GENES, AND GENES EXPRESSION .
. . . . . . . 31 3.2.2 BOWMAN-BIRK PROTEASE INHIBITORS FROM OTHER LEGUME
SEEDS . . . . . . . . . . . . . . . . . . . 33 3.2.2.1 FROM PEANUTS . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3.2.2.2 FROM
PEAS AND BEANS . . . . . . . . . . . . . . . . . . . . . . . 36 3.2.2.3
FROM MISCELLANEOUS LEGUME SEEDS . . . . . . . . . . . . 3 9 3.2.3
BOWMAN-BIRK PROTEASE INHIBITORS FROM OTHER SOURCES . . . . . . . . . . .
. . . . . . . . . . . . . 44 3.3 POTATO INHIBITOR FAMILIES . . . . . . .
. . . . . . . . . . . . . 46 3.3.1 GENERAL . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . 46 3.3.2 POTATO I INHIBITOR FAMILY
. . . . . . . . . . . . . . . . . . . . 46 3.3.3 POTATO II INHIBITOR
FAMILY . . . . . . . . . . . . . . . . . . . . 47 3.3.4 OTHER
POLYPEPTIDE INHIBITORS OF SERINE PROTEASES . . . . . . . . . . . . . . .
. . . . . . . . . . 48 3.3.5 CARBOXYPEPTIDASE INHIBITOR . . . . . . . .
. . . . . . . . . . 49 3.4 SQUASH INHIBITOR FAMILY . . . . . . . . . . .
. . . . . . . . . . 51 3.4.1 GENERAL . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . 51 3.4.2 ISOLATION AND CHARACTERIZATION
. . . . . . . . . . . . . . . . 52 3.4.3 STRUCTURE . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . 55 3.4.4 SYNTHESIS, GENES
AND GENES EXPRESSION . . . . . . . . . 56 3.5 BARLEY TRYPSIN INHIBITOR
FAMILY . . . . . . . . . . . . . . . 59 3.6 MISCELLANEOUS INHIBITORS OF
SERINE PROTEASES. . . . . 60 3.7 CYSTATINS (CYSTEINE PROTEASE
INHIBITORS) OF PLANT ORIGIN . . . . . . . . . . . . . . . . . . . . . .
. . . . . . 65 3.8 OTHER SPECIFICITIES OF INHIBITION . . . . . . . . . .
. . . . . 70 4 PLANT PROTEASE INHIBITORS IN NUTRITION . . . . . . . . .
75 4.1 EARLY OBSERVATIONS . . . . . . . . . . . . . . . . . . . . . . .
. . 75 4.2 EFFECT ON GROWTH AND ON THE PANCREAS . . . . . . . . . . 77
4.3 LONG-TERM FEEDING EFFECTS AND RELEVANCE TO HUMANS . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . 80 4.4 LATER NUTRITIONAL
STUDIES . . . . . . . . . . . . . . . . . . . . 81 4.5 CONCLUDING
REMARKS. . . . . . . . . . . . . . . . . . . . . . . . 84 5 PLANT
PROTEASE INHIBITORS AND PLANT PROTECTION . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . 85 5.1 GENERAL . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . 85 CONTENTS XI 5.2 EFFECT OF
PLANT PROTEASE INHIBITORS ON THE DEVELOPMENT OF INSECTS . . . . . . . .
. . . . . . . . 86 5.3 INDUCTION OF PLANT PROTEASE INHIBITORS IN PLANTS
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 5.4
INTRODUCTION OF PLANT PROTEASE INHIBITORS INTO PLANTS BY GENETIC
ENGINEERING . . . . . . . . . . . . 98 5.5 INDUCED RESISTANCE OF INSECTS
TO PLANT PROTEASE INHIBITORS . . . . . . . . . . . . . . . . . 105 5.6
ANTIFUNGAL PLANT PROTEASE INHIBITORS . . . . . . . . . . 109 6 PLANT
PROTEASE INHIBITORS AS CANCER CHEMOPREVENTIVE AGENTS . . . . . . . . . .
. . . . . . . . . 111 6.1 INTRODUCTORY REMARKS. . . . . . . . . . . . .
. . . . . . . . . 111 6.2 AT THE CELLULAR, TISSUE, AND ORGAN LEVELS . .
. . . . . 112 6.3 IN THE ORGANISM . . . . . . . . . . . . . . . . . . .
. . . . . . . 116 6.4 PROPOSED MECHANISMS OF ANTICARCINOGENESIS OF
PROTEASE INHIBITORS . . . . . . . . . . . . . . . . . . . . . . 120 7
OTHER ACTIVITIES OF PLANT PROTEASE INHIBITORS . . . 123 7.1 INTERACTION
WITH PLANT PROTEASES . . . . . . . . . . . . . . 123 7.2 PLANT PROTEASE
INHIBITORS AS ALLERGENS . . . . . . . . . 125 7.3 PLANT PROTEASE
INHIBITORS AND PROGRAMMED CELL DEATH IN PLANTS. . . . . . . . . . . . .
. . . . . . . . . . . 126 REFERENCES . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . 129 SUBJECT INDEX . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
|
any_adam_object | 1 |
author | Birk, Yehudith |
author_facet | Birk, Yehudith |
author_role | aut |
author_sort | Birk, Yehudith |
author_variant | y b yb |
building | Verbundindex |
bvnumber | BV015734664 |
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callnumber-label | QP609 |
callnumber-raw | QP609.P78 |
callnumber-search | QP609.P78 |
callnumber-sort | QP 3609 P78 |
callnumber-subject | QP - Physiology |
classification_rvk | WD 5065 WD 5090 WN 4000 |
classification_tum | CHE 870f CHE 832f CHE 820f |
ctrlnum | (OCoLC)50919984 (DE-599)BVBBV015734664 |
dewey-full | 572/.76 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 572 - Biochemistry |
dewey-raw | 572/.76 |
dewey-search | 572/.76 |
dewey-sort | 3572 276 |
dewey-tens | 570 - Biology |
discipline | Biologie Chemie |
format | Book |
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id | DE-604.BV015734664 |
illustrated | Illustrated |
indexdate | 2024-07-09T19:09:34Z |
institution | BVB |
isbn | 3540001182 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010121313 |
oclc_num | 50919984 |
open_access_boolean | |
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owner_facet | DE-M49 DE-BY-TUM DE-11 |
physical | XI, 170 S. Ill., graph. Darst. : 24 cm |
publishDate | 2003 |
publishDateSearch | 2003 |
publishDateSort | 2003 |
publisher | Springer |
record_format | marc |
spelling | Birk, Yehudith Verfasser aut Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk Berlin ; Heidelberg ; New York ; Hong Kong ; London ; Milan ; Pa Springer 2003 XI, 170 S. Ill., graph. Darst. : 24 cm txt rdacontent n rdamedia nc rdacarrier Literaturverz. S. 129 - 164 "Plant protease inhibitors are diverse in number and in specificity towards various proteolytic enzymes. This book focuses on the isolation, structure, characterization, physiochemical and physiological properties, synthesis, functions and mechanisms of action of plant protease inhibitors. It deals with their inhibitory effects on insects and pathogens with their induction and introduction into plants by genetic engineering for plant protection. The induced resistance of insects to the inhibitors and the hazards to friendly insects are also discussed. Futher, findings are presented on the cancer chemopreventive properties of the inhibitors at the cellular, tissue and organ levels and in the organism."--BOOK JACKET. Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd rswk-swf Proteaseinhibitor (DE-588)4130450-0 gnd rswk-swf Pflanzen (DE-588)4045539-7 s Proteaseinhibitor (DE-588)4130450-0 s DE-604 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010121313&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Birk, Yehudith Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd Proteaseinhibitor (DE-588)4130450-0 gnd |
subject_GND | (DE-588)4045539-7 (DE-588)4130450-0 |
title | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering |
title_auth | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering |
title_exact_search | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering |
title_full | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk |
title_fullStr | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk |
title_full_unstemmed | Plant protease inhibitors significance in nutrition, plant protection, cancer prevention and genetic engineering Yehudith Birk |
title_short | Plant protease inhibitors |
title_sort | plant protease inhibitors significance in nutrition plant protection cancer prevention and genetic engineering |
title_sub | significance in nutrition, plant protection, cancer prevention and genetic engineering |
topic | Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen (DE-588)4045539-7 gnd Proteaseinhibitor (DE-588)4130450-0 gnd |
topic_facet | Antineoplastic Agents Pest Control, Biological Phytochemicals Plant Extracts therapeutic use Plant Proteins Protease Inhibitors Protease inhibitors Pflanzen Proteaseinhibitor |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010121313&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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