Microbial foodborne diseases: mechanisms of pathogenesis and toxin synthesis
Gespeichert in:
Format: | Buch |
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Sprache: | English |
Veröffentlicht: |
Lancaster [u.a.]
Technomic Publ.
2000
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XXII, 550 S. graph. Darst. |
ISBN: | 1566767873 |
Internformat
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245 | 1 | 0 | |a Microbial foodborne diseases |b mechanisms of pathogenesis and toxin synthesis |c ed. by Jeffrey W. Cary ... |
264 | 1 | |a Lancaster [u.a.] |b Technomic Publ. |c 2000 | |
300 | |a XXII, 550 S. |b graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
650 | 7 | |a Food Poisoning |2 cabt | |
650 | 7 | |a Food Allergies |2 cabt | |
650 | 7 | |a Foodborne Diseases |2 cabt | |
650 | 4 | |a Alimentos - Toxicología | |
650 | 4 | |a Aliments - Microbiologie | |
650 | 4 | |a Maladies d'origine alimentaire - Pathogénèse | |
650 | 4 | |a Microbiología en alimentos y agricultura | |
650 | 4 | |a Toxinas bacterianas | |
650 | 4 | |a Toxines microbiennes | |
650 | 4 | |a Enterobacteriaceae Infections |x etiology | |
650 | 4 | |a Enterobacteriaceae Infections |x transmission | |
650 | 4 | |a Enterobacteriaceae |x pathogenicity | |
650 | 4 | |a Food Microbiology | |
650 | 4 | |a Food Poisoning |x etiology | |
650 | 4 | |a Food |x Microbiology | |
650 | 4 | |a Foodborne diseases |x Pathogenesis | |
650 | 4 | |a Microbial toxins | |
650 | 4 | |a Toxins |x biosynthesis | |
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Datensatz im Suchindex
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adam_text | Table of Contents
Foreword xiii
Preface xv
List of Contributors xix
Part I: Gram Negative Foodborne Bacterial Pathogens
1. MOLECULAR AND CELLULAR BIOLOGY OF SALMONELLA
PATHOGENESIS 3
FRANCISCO GARCIA DEL PORTILLO
1. Introduction 3
2. The Genus Salmonella 3
3. Diseases Caused by Salmonella Infections 4
4. Epidemiology of Salmonella Infections 5
5. Detection of Salmonella in Food and Water 6
6. Prevalence of Salmonella in Foods 6
7. Analysis of Salmonella Virulence Factors: In Vivo and In Vitro
Models 7
8. Cell Biology of the 5a/mo«e//a Eucaryotic Cell Interaction 8
9. Molecular Genetics of Salmonella Virulence 19
10. Conclusions and Future Perspectives 32
11. References 34
2. SHIGELLA INFECTIONS: EPIDEMIOLOGY, PATHOGENESIS
I AND HOST IMMUNE RESPONSE 51
CHRISTINE WENNERAS and PHILIPPE SANSONETTI
1. Bacteriology 52
v
vi Table of Contents
2. Lipopolysaccharide 53
3. Transmission 53
4. Epidemiology 54
5. Disease 55
6. Diagnosis 59
7. Animal Models 59
8. Pathogenic Mechanisms 60
9. Shigella and the Immune System 70
10. Adaptive Host Immune Responses 74
11. Treatment 76
12. Vaccination 77
13. Conclusion 77
14. References 78
3. THE MOLECULAR PATHOGENESIS OF ESCHERICHIA
COLI INFECTIONS 87
MICHAEL S. DONNENBERG and JAMES P. NATARO
1. Introduction 87
2. Enteropathogenic E. Coli (EPEC) 88
3. Enterohemorrhagic E. Coli (EHEC) 92
4. Enterotoxigenic E. Coli 95
5. Enteroaggregative E. Coli 101
6. Enteroinvasive E. Coli 105
7. Diffusely Adherent E. Coli 107
8. Uropathogenic E. Coli 109
9. E. Coli Strains That Cause Neonatal Meningitis 112
10. Summary 113
11. Acknowledgments 115
12. References 115
4. VIRULENCE DETERMINANTS OF THE BACTERIAL PATHOGEN
YERSINIA ENTEROCOLITICA: MODE OF ACTION AND GLOBAL
REGULATION 131
MARIE PAULE SORY and GUY R. CORNELIS
1. Introduction 131
2. Pathology 132
3. Interaction with Eukaryotic Host Cells 133
Table of Contents vii
4. Production and Regulation of Y. Enterocolitica Virulence
Factors 142
5. References 149
5. MOLECULAR PATHOGENESIS OF VIBRIO INFECTIONS 157
KENNETH M. PETERSON
1. Introduction 157
2. Vibrio Cholerae 158
3. Vibrio Cholerae Virulence Factors 159
4. ToxR Regulon 167
5. V. Cholerae Acquisition of Virulence Genes 172
6. Control of Cholera 173
7. Vibrio Parahaemolyticus 175
8. Vibrio Vulnificus 178
9. Vibrio Alginolyticus 180
10. Vibrio Fluvialis 180
11. Vibrio Hollisae 181
12. Vibrio Mimicus 181
13. Conclusions 182
14. References 183
6. MOLECULAR MECHANISMS GOVERNING CAMPYLOBACTER
PATHOGENICITY 191
L. S. MANSFIELD and S. R. ABNER
1. Introduction 191
2. Pathogenesis and Virulence Factors 196
3. Cell Association and Virulence Mechanisms 201
4. Genetic Basis for Virulence 210
5. Tools to Explore the Genetics of Virulence 216
6. Host Response to Campylobacter SPP. 220
7. Future Approaches 222
8. References 222
Part II: Gram Positive Foodborne Bacterial Pathogens
7. THE ACTION, GENETICS, AND SYNTHESIS OF CLOSTRIDIUM
PERFRINGENS ENTEROTOXIN 247
BRUCE A. McCLANE
1. Introduction 247
viii Table of Contents
2. Epidemiology of C. Perfringens Type A Food Poisoning 247
3. The Pathogenesis of C. Perfringens Type A Food
Poisoning 249
4. Evidence of CPE Involvement in C. Perfringens Type A Food
Poisoning 252
5. The Mechanism of Action of CPE 253
6. The CPE Protein 260
7. Genetics and Expression of CPE 263
8. Future Challenges 266
9. Acknowledgments 267
10. References 267
8. MECHANISMS OF PATHOGENESIS AND TOXIN SYNTHESIS
IN CLOSTRIDIUM BOTUUNUM 273
KEIJI OGUMA, YUKAKO FUJINAGA, KAORU INOUE and KENJI YOKOTA
1. Introduction 273
2. Classification of C. Botulinum Based on Toxin
Antigenicity 273
3. Classification of C. Botulinum Based on Biochemical
Properties 276
4. Botulism 276
5. Identification of Botulism 279
6. Structure and Function of NTXs 279
7. Structure and Function of Progenitor Toxins 281
8. Gene Organization 287
9. Conclusion 288
10. References 289
9. PATHOGENESIS DETERMINANTS OF USTERIA
MONOCYTOGENES 295
SOPHIA KATHARIOU
1. Introduction 295
2. Known Virulence Determinants 296
* 3. Usteria Host Cell Interaction 298
4. Adaptive Responses and Possible Impact on Pathogenesis of
L Monocytogenes 302
5. Epidemiological Aspects of Pathogenesis 303
6. Conclusions 306
7. Acknowledgments 307
8. References 307
Table of Contents ix
Part III: Fungal and Marine Toxins
10. AFLATOXINS: BIOLOGICAL SIGNIFICANCE AND
REGULATION OF BIOSYNTHESIS 317
JEFFREY W. CARY, DEEPAK BHATNAGAR and JOHN E. LIN2
1. Introduction 317
2. Molecular Biology of Aflatoxin Biosynthesis 324
3. Regulation of AF/ST Synthesis in Aspergillus 332
4. Future Focus 348
5. References 348
11. FUSARIUM TOXINS: TRICHOTHECENES AND FUMONISINS.... 363
ROBERT H. PROCTOR
1. Introduction 363
2. Trichothecenes 364
3. Fumonisins 370
4. Future Areas of Research 376
5. References 377
12. PSP TOXINS: THEIR BIOSYNTHESIS BY MARINE
DINOFLAGELLATES AND MOLECULAR IDENTIFICATION 383
YUZABURO ISHIDA and YOSHIHIKO SAKO
1. Introduction 383
2. Environmental Conditions Affect PSP Production 384
3. Biosynthesis of the Saxitoxin (STX) Skeleton 386
4. Biochemical and Molecular Analysis of PSP Toxin
Production 386
5. Genetic Analysis of PSP Toxin Production by Mating
Reactions 390
6. Molecular Identification of Alexandrium spp. and Related
Dinoflagellates 393
7. Acknowledgments 397
8. References 397
Part IV: Parasitic Protozoa
13. TOXOPLASMA GONDII STRAIN VARIATION
AND PATHOGENICITY 405
JUDITH E. SMITH and NAOMI REBUCK
1. Introduction 405
x Table of Contents
2. Toxoplasma: An Unusual Apicomplexan Parasite 406
3. Toxoplasma: A Human Pathogen 411
4. Toxoplasma: Strain Variation and Virulence 415
5. A Foodborne Pathogen 421
6. Acknowledgments 423
7. References 423
14. ENTAMOEBA HISTOLYTICA AND CRYPTOSPORIDIUM
PARVUM 433
UPINDER SINGH, THEODORE S. STEINER and BARBARA J. MANN
1. Introduction 433
2. Entamoeba Histolytica 434
3. Cryptosporidium Parvum 448
4. References 455
Part V: Viruses and Related Infectious Agents
15. NORWALK AND OTHER HUMAN CALICIVIRUSES:
MOLECULAR CHARACTERIZATION, EPIDEMIOLOGY,
AND PATHOGENESIS 469
KELLOGG J. SCHWAB, MARY K. ESTES and ROBERT L. ATMAR
1. Impact of Foodborne Disease Caused by Norwalk Virus and
Human Caliciviruses 469
2. Norwalk Virus and Other Human Caliciviruses 473
3. How Can the HuCVs Be Detected 477
4. Mechanisms of Pathogenesis 481
5. Summary of New Areas of Research 483
6. Acknowledgments 484
7. References 484
16. MOLECULAR BIOLOGY OF PRION DISEASES 495
CORINNE IDA LASMEZAS and STEFAN WEISS
1. Introduction 495
2. History and Epidemiology of TSE 497
3. Histopathological Features of TSE 500
4. The Prion 500
5. Replication Mechanisms of Prions 507
6. Peripheral Pathogenesis of Prions 512
7. The Life Cycle of Prions Including the Role of Possible Prion
Receptors 515
Table of Contents xi
8. Prion Like Elements in the Yeast (Sup35p, Ure2p) 517
9. The Prion Like Element Het s in Podospora Anserina 519
10. Three Different Factors Leading to TSE: Sporadic, Familial,
Transmitted (Iatrogenic) 519
11. Transmission Studies and Species Barriers—CJD—New Variant
CJD 521
12. Diagnostics for TSE 525
13. Therapeutics for TSE 527
14. Concluding Remarks 529
15. Acknowledgments 529
16. References 529
Index 539
About the Editors 549
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spelling | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis ed. by Jeffrey W. Cary ... Lancaster [u.a.] Technomic Publ. 2000 XXII, 550 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Food Poisoning cabt Food Allergies cabt Foodborne Diseases cabt Alimentos - Toxicología Aliments - Microbiologie Maladies d'origine alimentaire - Pathogénèse Microbiología en alimentos y agricultura Toxinas bacterianas Toxines microbiennes Enterobacteriaceae Infections etiology Enterobacteriaceae Infections transmission Enterobacteriaceae pathogenicity Food Microbiology Food Poisoning etiology Foodborne diseases Pathogenesis Microbial toxins Toxins biosynthesis Lebensmittelvergiftung (DE-588)4034915-9 gnd rswk-swf Lebensmittelinfektion (DE-588)4274039-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lebensmittelinfektion (DE-588)4274039-3 s DE-604 Lebensmittelvergiftung (DE-588)4034915-9 s Cary, Jeffrey W. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010086073&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis Food Poisoning cabt Food Allergies cabt Foodborne Diseases cabt Alimentos - Toxicología Aliments - Microbiologie Maladies d'origine alimentaire - Pathogénèse Microbiología en alimentos y agricultura Toxinas bacterianas Toxines microbiennes Enterobacteriaceae Infections etiology Enterobacteriaceae Infections transmission Enterobacteriaceae pathogenicity Food Microbiology Food Poisoning etiology Foodborne diseases Pathogenesis Microbial toxins Toxins biosynthesis Lebensmittelvergiftung (DE-588)4034915-9 gnd Lebensmittelinfektion (DE-588)4274039-3 gnd |
subject_GND | (DE-588)4034915-9 (DE-588)4274039-3 (DE-588)4143413-4 |
title | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis |
title_auth | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis |
title_exact_search | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis |
title_full | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis ed. by Jeffrey W. Cary ... |
title_fullStr | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis ed. by Jeffrey W. Cary ... |
title_full_unstemmed | Microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis ed. by Jeffrey W. Cary ... |
title_short | Microbial foodborne diseases |
title_sort | microbial foodborne diseases mechanisms of pathogenesis and toxin synthesis |
title_sub | mechanisms of pathogenesis and toxin synthesis |
topic | Food Poisoning cabt Food Allergies cabt Foodborne Diseases cabt Alimentos - Toxicología Aliments - Microbiologie Maladies d'origine alimentaire - Pathogénèse Microbiología en alimentos y agricultura Toxinas bacterianas Toxines microbiennes Enterobacteriaceae Infections etiology Enterobacteriaceae Infections transmission Enterobacteriaceae pathogenicity Food Microbiology Food Poisoning etiology Foodborne diseases Pathogenesis Microbial toxins Toxins biosynthesis Lebensmittelvergiftung (DE-588)4034915-9 gnd Lebensmittelinfektion (DE-588)4274039-3 gnd |
topic_facet | Food Poisoning Food Allergies Foodborne Diseases Alimentos - Toxicología Aliments - Microbiologie Maladies d'origine alimentaire - Pathogénèse Microbiología en alimentos y agricultura Toxinas bacterianas Toxines microbiennes Enterobacteriaceae Infections etiology Enterobacteriaceae Infections transmission Enterobacteriaceae pathogenicity Food Microbiology Food Poisoning etiology Foodborne diseases Pathogenesis Microbial toxins Toxins biosynthesis Lebensmittelvergiftung Lebensmittelinfektion Aufsatzsammlung |
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