Brain mapping: the methods
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Acad. Press
2002
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVII, 877 S. zahlr. Ill., graph. Darst. |
| ISBN: | 0126930198 |
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Contributors xi
Preface xv
Acknowledgments xvii
I Introduction
1 Introduction to
Cartography of the Brain
Arthur W. Toga and John C. Mazziotta
I. Introduction to Cartography 3
II. The Dimensions of a Brain Map 6
III. The Full Scope of Brain Mapping 1 1
IV Relationships to Other Biological Maps 14
V Stereotaxy 15
VI. Nomenclature 17
VII. Detection Devices 18
VIII. Brain Maps: Content and Format 21
IX. Summary 25
References 26
2 Time and Space
John C. Mazziotta
I. Introduction 33
II. Critical Variables in Brain Mapping
Techniques 34
III. The Concept of Resolution 36
IV Sampling 40
V Sites Accessed 43
VI. Invasiveness 44
v
tents
VII. Conclusions 44
References 45
II Surface Based Data
Acquisition
3 Optical Imaging of Neural Structure and
Physiology: Confocal Fluorescence
Microscopy in Live Brain Slices
Michael E. Dai ley
I. Introduction 49
II. Live Brain Slice Preparation and
Culture 51
III. Labeling Neuronal and Glial Cells in Brain Tissue
Slices 52
IV Imaging Methodology 57
V Application: Mapping Neural Structure and
Physiology in Developing Brain Slices 61
VI. Conclusions and Future Prospects 71
References 73
4 Voltage and Calcium Imaging of Brain
Activity: Examples from the Turtle
and the Mouse
Matt Wachowiak, Chun X. Falk, Lawrence B. Cohen,
and Michal R. Zochowski
I. Why (and Why Not) Voltage and Calcium
Imaging 77
II. Signal Type 78
III. Dyes 78
r
vi
IV Amplitude of the Voltage or Calcium
Change 81
V Noise in the Optical Measurements 81
VI. Light Sources 83
VII. Optics 83
VIII. Cameras 84
IX. Comparison of Local Field Potential and
Voltage Sensitive Dye Recording 85
X. Voltage Sensitive Dye Recording in the Turtle
Olfactory Bulb 85
XI. Calcium Dye Recording in the Mouse Olfactory
Bulb 89
XII. Intrinsic Imaging and Fluorescence Signals from
In Vivo Mammalian Brain 93
XIII. Summary and Future Directions 93
References 94
5 Optical Imaging Based on Intrinsic Signals
Nader Pouratian and Arthur W. Toga
I. Introduction 97
II. Sources of Intrinsic Signals and Wavelength
Dependency 98
III. Preparation of an Animal for Optical
Imaging 103
IV The Apparatus 107
V Data Acquisition 1 12
VI. Data Analysis for Mapping Functional
Architecture 1 14
VII. Chronic Optical Imaging 121
VIII. Optical Imaging of the Human
Neocortex 123
IX. Combining Optical Imaging with Other
Techniques 125
X. Applications 130
XI. Comparison of Intrinsic Optical Imaging with
Other Imaging Techniques 135
XII. Conclusions and Outlook 136
References 137
6 Near Infrared Spectroscopy and Imaging
Arno Villringer and Hellmuth Obrig
I. Introduction 141
II. Optical Window for Noninvasive
Studies 142
III. Other Optical Parameters Relevant for Near
Infrared Studies 143
IV Technical Approaches for Near Infrared
Spectroscopy and Imaging 143
5 Optical Imaging Based on Intrinsic Signals
V Physiological Parameters of MRS
Measurements 144
VI. Near Infrared Spectroscopy and Imaging:
Applications 149
VII. Practical Aspects of MRS
Measurements 151
VIII. Problems and Perspectives 155
References 156
7 Dynamic Measurements of Local
Cerebral Blood Flow: Examples
from Rodent Whisker Barrel Cortex
Thomas A. Woolsey, Ling Wei, and Joseph R Erinjeri
I. Why Measure Local Cerebral Blood
Flow? 159
II. Function and Structural Contexts 160
III. Global Tracers 161
IV Volatile Tracers 162
V Doppler Flowmetry 163
VI. Video Microscopy 163
VII. Localization of Activity Changes 164
VIII. Diameter 165
IX. Intravascular Dyes 166
X. Intravascular Particles 167
XI. Localization of Flow Changes 169
XII. Conclusions and Prospects 169
References 170
8 Electrophysiological Imaging of
Brain Function
Alan Gevins
I. Introduction 175
II. The Electroencephalogram and Averaged
Event Related Potentials 176
III. Improving the Spatial Resolution of the
Electroencephalogram 179
IV Analysis of Functional Networks 183
V The EEG as a Monitoring (vs Imaging)
Modality 185
VI. Summary and Conclusions 186
References 186
9 Electrophysiological Methods for Mapping
Brain Motor and Sensory Circuits
Paul D. Cheney
I. Introduction and Historical Perspective 190
II. Structural versus Functional Brain
Maps 191
10 Magnetoencephalographic Characterization ol
III. Strengths of Electrophysiological Mapping
Methods Compared to Other Brain Mapping
Methods 191
IV Contrasts between Sensory versus Motor System
Mapping 192
V Output Measures for Mapping Motor System
Organization 194
VI. Electrical Stimulation and Other Input
Measures for Mapping Motor System
Organization 195
VII. Mapping Motor Output with Transcranial
Stimulation of Cortex 197
VIII. Mapping Motor Output with Electrical
Stimulation of the Cortical Surface 205
IX. Mapping Motor Output with Intracortical
Microstimulation (ICMS) 209
X. Mapping Motor Output with High Density
Microelectrode Arrays 21 1
XI. Mapping Motor Output with Spike Triggered
Averaging of EMG Activity from Single
Neurons 213
XII. Mapping Motor Output with Stimulus Triggered
Averaging of EMG Activity (Single Pulse
ICMS) 216
XIII. Comparison of Results from Spike Triggered
Averaging, Stimulus Triggered Averaging, and
Repetitive ICMS 219
XIV Mapping the Output Terminations of Single
Neurons Electrophysiologically 221
XV The Future of Electrophysiological
Mapping 222
References 223
10 Magnetoencephalographic
Characterization of Dynamic Brain
Activation: Basic Principles and Methods
of Data Collection and Source Analysis
Matti Hamalainen and Riitta Hari
I. Introduction 227
II. Generation of Neuromagnetic Fields 228
III. Instrumentation and Data Acquisition 233
IV Source Analysis 238
V Neuromagnetic Studies 244
VI. Conclusions and Future Directions 248
References 250
11 Transcranial Magnetic Stimulation
Alvaro Pascual Leone and Vincent Walsh
I. Introduction 255
c Dynamic Brain Activation vii
II. Basic Principles of Magnetic Brain
Stimulation 256
III. TMS in Clinical Neurophysiology 263
IV TMS in Cognitive Neuroscience 270
V TMS Limitations 279
References 285
III Tomographic Based Data
Acquisition
12 High Field Magnetic Resonance
Kamil Ugurbil
I. Introduction 291
II. Signal to Noise Ratio 292
III. Functional Brain Imaging 293
IV Spectroscopy at High Magnetic Fields 306
References 31 1
13 Functional MRI
Joseph B. Mandeville and Bruce R. Rosen
I. Introduction 315
II. MRI: A Brief Primer 316
III. From MRI to fMRI 320
IV Physics and Physiology 322
V Sensitivity 330
VI. Resolution 336
VII. Structure Function Integration 343
VII. Future 344
References 344
14 Magnetic Resonance Spectroscopic
Imaging
Andrew A. Maudsley
I. Introduction 351
II. Basics of in Vivo MR Spectroscopy 352
III. MRSI Data Acquisition Methods 357
IV Data Processing Methods 361
V MRSI Data Analysis 366
VI. Applications 371
VII. Emerging Technologies 373
VIII. Conclusion 373
References 374
15 Principles, Methods, and Applications
of Diffusion Tensor Imaging
Susumu Mori
I. Diffusion Measurement by NMR 379
viii 16 Ne
II. Diffusion Tensor Imaging 384
III. Data Visualization and Analysis of DTI 388
IV Application Studies 391
V Summary 395
References 395
16 Neuroanatomical Micromagnetic
Resonance Imaging
R T. Narasimhan and Russell E. Jacobs
I. Introduction 399
II. Magnetic Resonance Basics 400
III. Magnetic Resonance Imaging Basics 403
IV k Space and MR Images 405
V Signal to Noise Ratio (SNR) and
Contrast to Noise Ratio (CNR) 406
VI. T, and T2 lnduced Contrasts 407
VII. Diffusion Weighted, Perfusion, and Water
Displacement Imaging 409
VIII. Microscopic MRI 411
IX. Micromagnetic Resonance Imaging of the
Nervous System 413
X. Concluding Remarks 419
References 421
17 CT Angiography and CT
Perfusion Imaging
M. H. Lev and R. G. Gonzalez
I. Introduction 427
II. Technical Background 431
III. Scanning Protocols: Acquisition, Postprocessing,
Analysis, and Interpretation 456
IV Clinical Utility 462
V Conclusions 476
References 478
18 Imaging Brain Function with Positron
Emission Tomography
Simon R. Cherry and Michael E. Phelps
I. Introduction 485
II. Basic Overview and Principles of PET 486
III. Preparation of Positron Labeled
Compounds 487
IV PET Scanners 489
V PET Data Correction and Image
Reconstruction 494
VI. Tracer Kinetic Models 498
VII. Task Specific Mapping of the Human
Brain 501
?uroanatomical Micromagnetic Resonance Imaging
VIII. Mapping Brain Function in Development and
Disease 504
IX. High Resolution PET Studies in Animal
Models 506
X. Summary 508
References 508
19 SPECT Functional Brain Imaging
Michael D. Devous, Sr.
I. Introduction 513
II. Instrumentation 514
III. Radiopharmaceuticals 520
IV Factors That Affect Image Appearance 525
V Intercomparison of Neuroimaging Techniques
for the Quantification of rCBF 528
VI. Radiation Risk Issues 532
VII. Conclusions 533
References 533
IV Postmortem
20 Postmortem Anatomy
Jacopo Annese and Arthur W. Toga
I. Introduction 537
II. The Representation of Anatomy 538
III. The Specimen 539
IV Preservation of Anatomical
Information 541
V Preparing the Specimen for Cutting 543
VI. Histological Slides 544
VII. Histological Methods 546
VIII. Anatomical Visualization 553
IX. Quantification 557
X. 3D Reconstruction 558
XI. Epilogue 562
References 564
21 Quantitative Analysis of Cyto and
Receptor Architecture of the Human Brain
Karl Zilles, Axel Schleicher, Nicola Palomero Gallagher,
and Katrin Amunts
I. Introduction 573
II. Principles of Cytoarchitectonic Analysis 575
III. Observer Independent Mapping of the Human
Cerebral Cortex 579
IV Quantitative Autoradiography of Different
Receptor Binding Sites 587
V Perspectives of Architectonic Mapping 598
22 Statistics I: Experimental Design and Statistical
References 599
V Analysis
22 Statistics I: Experimental Design and
Statistical Parametric Mapping
Karl J. Friston
I. Introduction 605
II. Functional Specialization and
Integration 606
III. Spatial Realignment and
Normalization 607
IV Statistical Parametric Mapping 610
V Experimental Design 616
VI. Designing fMRI Studies 618
VII. Inferences about Subjects and
Populations 624
VIII. Effective Connectivity 626
References 630
23 Statistics II: Correlation of Brain
Structure and Function
Roger R Woods
I. Introduction 633
II. Intrasubject Multimodal Integration 635
III. Clinical Examples of Intrasubject Multimodal
Registration 640
IV Intersubject Multimodal Integration 649
V Conclusion 657
References 657
24 Advanced Nonrigid Registration
Algorithms for Image Fusion
Simon K. Warfield, Alexandra Guimond, Alexis Roche, Aditya
Bharatha, Alida Tei, Florin Talos, Jan Rexilius, Juan Ruiz
Alzola, Carl Fredrik Westin, Steven Haker, Sigurd Angenent,
Allen Tannenbaum, Ferenc Jolesz, and Ron Kikinis
I. Introduction 661
II. Intermodality and Multicontrast
Images 662
III. Image Fusion during Neurosurgery with a
Biomechanical Model of Brain
Deformation 668
IV Physics Based Regularization with an Empirical
Model of Anatomical Variability 674
V Registration of Diffusion Tensor
Images 677
VI. The Monge Kantorovich Problem and Image
Registration 683
References 687
Parametric Mapping ix
25 Combination of Transcranial Magnetic
Stimulation and Brain Mapping
Tomas Paus
I. Introduction 691
II. Neurophysiological Underpinnings of the
Signal 691
III. Combination of TMS and Brain
Mapping 693
IV Conclusion 702
References 703
26 Volume Visualization
Andreas Pommert, Ulf Tiede, and Karl Heinz Hohne
I. Introduction 707
II. Segmentation 709
III. Surface Extraction 711
IV Direct Volume Visualization 712
V Visualization of Transformed Data 717
VI. Image Fusion 717
VII. Intelligent Visualization 718
VIII. Image Quality 720
IX. Conclusions 720
References 721
VI Databases and Atlases
27 The International Consortium for Brain
Mapping: A Probabilistic Atlas and
Reference System for the Human Brain
John Mazziotta for the International Consortium
for Brain Mapping
I. Introduction 727
II. Motivation for Developing a Probabilistic Human
Brain Atlas 728
III. Strategy and Rationale 729
IV Methods and Results 741
V Other Issues 749
VI. Limitations and Deliverables 749
VII. Conclusions 750
References 751
28 Subpopulation Brain Atlases
Paul M. Thompson, Michael S. Mega, and Arthur W. Toga
I. Population Based Brain Imaging 757
II. Atlases in Brain Mapping 759
III. Anatomical Modeling 761
IV Population Maps of the Cortex 766
X
V Brain Averaging 773
VI. Atlas Statistics: Probabilistic Atlases 775
VII. Applications to Development and
Disease 779
VIII. Dynamic Brain Maps 780
IX. Genetic Brain Maps 784
X. Subpopulation Selections 786
XI. Conclusions 788
References 788
VII Emerging Concepts
29 Radionuclide Imaging of Reporter
Gene Expression
Gobalakrishnan Sundaresan and Sanjiv S. Gambhir
I. Overview of Molecular Imaging 799
II. Instrumentation for Molecular Imaging 800
III. Reporter Genes 800
IV Adapting the Reporter Gene Concept for
Radionuclide Imaging 801
V Application of in Vivo Reporter Gene Imaging to
Monitor Gene Therapy Regimens 806
VI. Indirect Imaging of Endogenous Gene
Expression through Coupling Endogenous
Promoters with Reporter Genes 809
VII. Antisense Reporter Probes for Imaging
Endogenous Gene Expression in Vivo 812
VIII. Nonradionuclide Approaches to Reporter Gene
Imaging 812
28 Subpopulation Brain Atlases
IX. Specific Issues for Neuroscience
Applications 813
X. Human Gene Therapy of Brain Tumors and
Imaging Studies 813
XI. Conclusion 815
References 815
30 Mapping Gene Expression by MRI
Angelique Y. Louie, Joseph A. Duimstra,
and Thomas J. Meade
I. Introduction 819
II. MRI Contrast Agents 819
III. Biochemically Activated MR Contrast
Agents 821
IV Targeted MR Contrast Agents 823
V Magnetic Resonance Spectroscopy and Gene
Expression 825
VI. Conclusion 827
References 827
31 Speculations about the Future
John C. Mazziotta and Arthur W. Toga
I. Introduction 831
II. Previous Predictions and Their
Outcomes 831
III. New Predictions 840
IV Conclusion 853
References 853
Index 859
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| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | Acad. Press |
| record_format | marc |
| spelling | Brain mapping the methods ed. by Arthur W. Toga ... 2. ed. Amsterdam [u.a.] Acad. Press 2002 XVII, 877 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Imagem por ressonância magnética larpcal Mapeamento cerebral larpcal Tomografia larpcal Brain mapping Methodology Brain mapping methods Brain anatomy & histology Brain physiology Magnetic Resonance Imaging methods Methode (DE-588)4038971-6 gnd rswk-swf Gehirnkarte (DE-588)4196204-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Gehirnkarte (DE-588)4196204-7 s DE-604 Methode (DE-588)4038971-6 s DE-188 Toga, Arthur W. Sonstige (DE-588)108329315X oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010067414&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Brain mapping the methods Imagem por ressonância magnética larpcal Mapeamento cerebral larpcal Tomografia larpcal Brain mapping Methodology Brain mapping methods Brain anatomy & histology Brain physiology Magnetic Resonance Imaging methods Methode (DE-588)4038971-6 gnd Gehirnkarte (DE-588)4196204-7 gnd |
| subject_GND | (DE-588)4038971-6 (DE-588)4196204-7 (DE-588)4143413-4 |
| title | Brain mapping the methods |
| title_auth | Brain mapping the methods |
| title_exact_search | Brain mapping the methods |
| title_full | Brain mapping the methods ed. by Arthur W. Toga ... |
| title_fullStr | Brain mapping the methods ed. by Arthur W. Toga ... |
| title_full_unstemmed | Brain mapping the methods ed. by Arthur W. Toga ... |
| title_short | Brain mapping |
| title_sort | brain mapping the methods |
| title_sub | the methods |
| topic | Imagem por ressonância magnética larpcal Mapeamento cerebral larpcal Tomografia larpcal Brain mapping Methodology Brain mapping methods Brain anatomy & histology Brain physiology Magnetic Resonance Imaging methods Methode (DE-588)4038971-6 gnd Gehirnkarte (DE-588)4196204-7 gnd |
| topic_facet | Imagem por ressonância magnética Mapeamento cerebral Tomografia Brain mapping Methodology Brain mapping methods Brain anatomy & histology Brain physiology Magnetic Resonance Imaging methods Methode Gehirnkarte Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010067414&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT togaarthurw brainmappingthemethods |