Analytical methods in combinatorial chemistry:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Lancaster, PA [u.a.]
Technomic Publ.
2000
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 268 S. graph. Darst. |
| ISBN: | 1566768098 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804129626572718080 |
|---|---|
| adam_text | ANALYTICAL METHODS IN COMBINATORIAL CHEMISTRY BBVGYAN AXYS ADVANCED
TECHNOLOGIES, INC. SOUTH SAN FRANCISCO, CA TECHNOMIC LISHINGCO..INC.J T
.ANCASTER * BASET, TABLE OF CONTENTS FOREWORD IX PREFACE XI
ACKNOWLEDGMENTS XV 1/ANALYTICAL ISSUES IN COMBINATORIAL CHEMISTRY 1
COMBINATORIAL CHEMISTRY 1 SYNTHESIS METHODS 3 ANALYTICAL CHALLENGES 6
REFERENCES 8 2 /AN EXAMINATION OF THE ANALYTICAL SAMPLE: RESIN SUPPORT-
. 12 PHYSICAL PROPERTIES OF RESINS 13 RESIN SWELLING AND SOLVATION 19
EFFECTS OF THE SOLVATED RESIN ON SOLID-PHASE REACTIONS 29 SUMMARY 46 3 /
SOLID-PHASE REACTION OPTIMIZATION USING FTIR METHODS 52 COMPARISON OF
FTIR AND RAMAN TECHNIQUES 53 THE MONITORING OF REACTIONS ON
POLYSTYRENE-BASED RESIN 66 THE MONITORING OF REACTIONS ON PS-PEG RESINS:
COMPARING THE REACTION RATE ON PS AND PS-PEG RESINS 86 VI TABLE OF
CONTENTS THE MONITORING OF REACTIONS ON SURFACE- FUNCTIONALIZED POLYMERS
93 SUMMARY 96 REFERENCES 96 4 / REACTION OPTIMIZATION USING MS AND NMR
METHODS 100 MS METHODS 100 NMR METHODS 101 SUMMARY 121 REFERENCES 122 5
/ REACTION OPTIMIZATION USING SPECTROPHOTOMETRIC AND OTHER METHODS 126
QUALITATIVE ANALYSIS OF AMINES 127 QUANTITATIVE ANALYSIS OF AMINES 130
QUANTITATIVE SPECTROSCOPIC METHODS FOR ORGANIC FUNCTIONAL GROUPS 137
COMBUSTION ELEMENTAL ANALYSIS METHODS 146 ELECTROCHEMICAL METHODS 151
ON-RESIN X-RAY, EPR, AND FLUORESCENCE METHODS 153 SUMMARY 154 REFERENCES
154 6 / QUALITY CONTROL OF COMBINATORIAL LIBRARIES 158 ANALYSIS OF
DISCRETE COMPOUND LIBRARIES 158 ANALYSIS OF POOLED LIBRARIES 164 HPLC
FOR ANALYZING COMPOUNDS FROM DISCRETE AND MIXTURE LIBRARIES 178 SUMMARY
182 REFERENCES 182 7 / SELECTION OF ACTIVE COMPOUNDS FROM COMBINATORIAL
LIBRARIES 187 IN-SOLUTION SCREENING OF COMBINATORIAL LIBRARIES 187
AFFINITY SELECTION OF LEAD COMPOUNDS BY MASS SPECTROMETRY 192 AFFINITY
CAPILLARY ELECTROPHORESIS 204 AFFINITY NMR 208 OTHER AFFINITY SELECTION
METHODS 214 ENCODING METHODS 217 SUMMARY 230 REFERENCES 232 TABLE OF
CONTENTS VII 8 / OPTIMIZATION OF LEAD COMPOUNDS 237 LEAD COMPOUNDS AND
LEAD OPTIMIZATION 237 OPTIMIZING THE IN VITRO ACTIVITY: SAR BY NMR 238
OPTIMIZING PHYSIOCHEMICAL PROPERTIES 248 SUMMARY 254 REFERENCES 254 9 /
FINAL THOUGHTS AND FUTURE PERSPECTIVES 257 REACTION OPTIMIZATION EFFORTS
258 MINIATURIZED ANALYSIS 259 PARALLEL ANALYSIS 260 HT NMR DATA
INTERPRETATION 261 LC-NMR-MS 261 REFERENCES 261 INDEX 265
|
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| spelling | Yan, Bing Verfasser aut Analytical methods in combinatorial chemistry Bing Yan Lancaster, PA [u.a.] Technomic Publ. 2000 XV, 268 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Combinatorial chemistry Kombinatorische Synthese (DE-588)4513555-1 gnd rswk-swf Chemische Analyse (DE-588)4009840-0 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Kombinatorische Synthese (DE-588)4513555-1 s Chemische Analyse (DE-588)4009840-0 s DE-604 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010052751&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Yan, Bing Analytical methods in combinatorial chemistry Combinatorial chemistry Kombinatorische Synthese (DE-588)4513555-1 gnd Chemische Analyse (DE-588)4009840-0 gnd |
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| title | Analytical methods in combinatorial chemistry |
| title_auth | Analytical methods in combinatorial chemistry |
| title_exact_search | Analytical methods in combinatorial chemistry |
| title_full | Analytical methods in combinatorial chemistry Bing Yan |
| title_fullStr | Analytical methods in combinatorial chemistry Bing Yan |
| title_full_unstemmed | Analytical methods in combinatorial chemistry Bing Yan |
| title_short | Analytical methods in combinatorial chemistry |
| title_sort | analytical methods in combinatorial chemistry |
| topic | Combinatorial chemistry Kombinatorische Synthese (DE-588)4513555-1 gnd Chemische Analyse (DE-588)4009840-0 gnd |
| topic_facet | Combinatorial chemistry Kombinatorische Synthese Chemische Analyse Aufsatzsammlung |
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