Photoreceptors and calcium:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Kluwer Acad., Plenum Publ. [u.a.]
2002
|
| Schriftenreihe: | Advances in experimental medicine and biology
514 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XXIV, 625 S. Ill., graph. Darst |
| ISBN: | 0306474158 |
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| 245 | 1 | 0 | |a Photoreceptors and calcium |c ed. by Wolfgang Baehr ; Krzysztof Palczewski |
| 264 | 1 | |a New York [u.a.] |b Kluwer Acad., Plenum Publ. [u.a.] |c 2002 | |
| 300 | |a XXIV, 625 S. |b Ill., graph. Darst | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Advances in experimental medicine and biology |v 514 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Calciprotéines - Effets physiologiques | |
| 650 | 4 | |a Calcium - Effets physiologiques | |
| 650 | 4 | |a Canaux à calcium | |
| 650 | 4 | |a Rétine | |
| 650 | 4 | |a Œil - Aspect moléculaire | |
| 650 | 4 | |a Calcium channels | |
| 650 | 4 | |a Calcium |x Physiological effect | |
| 650 | 4 | |a Calcium |x metabolism | |
| 650 | 4 | |a Calcium-Binding Proteins | |
| 650 | 4 | |a Calcium-binding proteins |x Physiological effect | |
| 650 | 4 | |a Eye |x Molecular aspects | |
| 650 | 4 | |a Light Signal Transduction | |
| 650 | 4 | |a Photoreceptor Cells, Vertebrate | |
| 650 | 4 | |a Retina | |
| 650 | 0 | 7 | |a Calcium |0 (DE-588)4069806-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Photorezeptor |0 (DE-588)4045934-2 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Photorezeptor |0 (DE-588)4045934-2 |D s |
| 689 | 0 | 1 | |a Calcium |0 (DE-588)4069806-3 |D s |
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| 700 | 1 | |a Baehr, Wolfgang |e Sonstige |4 oth | |
| 700 | 1 | |a Palczewski, Krzysztof |e Sonstige |4 oth | |
| 830 | 0 | |a Advances in experimental medicine and biology |v 514 |w (DE-604)BV000003102 |9 514 | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-010036391 | ||
Datensatz im Suchindex
| _version_ | 1804129603713761280 |
|---|---|
| adam_text | CONTENTS
COLOR PLATES xxv
1. CALCIUM AND PHOTOTRANSDUCTION 1
Kei Nakatani, Chunhe Chen, King Wai Yau, and Yiannis Koutalos
Abstract 1
Introduction ........ 1
The Effects and Targets of Calcium 2
Measuring the Effects of Calcium 6
Calcium and Regulation of Light Sensitivity 10
Conclusion 17
2. THE CALCIUM GRADIENT ALONG THE ROD
OUTER SEGMENT 21
K. Nicholas Leibovic
Abstract 21
Introduction 21
The Calcium Gradient 25
Discussion 30
3. THE TIME COURSE OF LIGHT ADAPTATION
IN VERTEBRATE RETINAL RODS 37
Peter D. Calvert and Clint L. Makino
Abstract 37
Introduction 37
How is Light Adaptation Manifested? 39
How can Adaptation Near Saturation be Studied? 42
How Rapidly can Adaptation Operate? 48
What is the Total Desensitization? 48
What are the Mechanisms of Fast Adaptation? 48
What Underlies the Slow Phase of Adaptation? 54
XV
xvi Contents
Model of Light Adaptation During Continuous Illumination 57
Why So Many Mechanisms? 57
4. S MODULIN 61
Satoru Kawamura and Shuji Tachibanaki
Abstract 61
Isolation 61
Function 62
Mechanism of Inhibition of Rhodopsin Phosphorylation 63
Site of the Interaction of S Modulin to Rhodopsin Kinase 64
Structure 64
Localization .¦.¦•........ ....66
5. Ca2+ DEPENDENT CONTROL OF RHODOPSIN
PHOSPHORYLATION: RECOVERIN AND
RHODOPSIN KINASE 69
Ivan I. Senin, Karl Wilhelm Koch, Mohammad Akhtar and Pavel P. Philippov
Abbreviations 69
Introduction 70
Recoverin 70
Rhodopsin Kinase 76
Recoverin as a Ca2+ Sensor of Rhodopsin Kinase in vitro 82
Is Recoverin a Caz+ Sensor of Rhodopsin Kinase in vivo? 90
Conclusion. Recoverin: Many Functions or an Unknown Function? 92
6. RECOVERIN AND RHODOPSIN KINASE 101
Ching Kang Jason Chen
Abstract 101
Introduction .....¦•....•..•••¦•¦• 101
RK and Phototransduction 102
Recoverin ....••.......•.••......••..••••••••.••.... .•...•......•.....••.••••....•..•.....•.••.. 102
Physiological Role of Ca2* Dependent Recoverin/Rhodopsin Kinase
Interaction in Phototransduction 103
Concluding Remarks 104
7. PATHOLOGICAL ROLES OF RECOVERIN
IN CANCER ASSOCIATED RETINOPATHY 109
Hiroshi Ohguro and Mitsuru Nakazawa
Abstract 109
CAR is an Ocular Paraneoplastic Manifestation 109
Clinical Aspects of CAR Ill
Molecular Pathology in CAR ~ 115
Conclusion 122
Contents xvii
8. RGS9 1 PHOSPHORYLATIONAND Ca2+ 125
Theodore G. Wensel
Abstract 125
Introduction: GTP Hydrolysis and Photoresponse Kinetics 125
RGS9 1, the GTPase Accelerating Protein (GAP) for Phototransduction 126
Domain and Subunit Structure of RGS9 1 126
Unique C Terminus of RGS9 1 126
Phosphorylation of RGS9 1 126
Effect of Ca2+ on Phosphorylation 128
Effect of Light on Phosphorylation of RGS9 1 128
Conclusion and Remaining Questions 128
References 129
9. PHOSPHORYLATION BY CYCLIN DEPENDENT PROTEIN
KINASE 5 OF THE REGULATORY SUBUNIT (Py) OF
RETINAL cGMP PHOSPHODIESTERASE (PDE6):
ITS IMPLICATIONS IN PHOTOTRANSDUCTION 131
Akio Yamazaki, Oleg Moskvin and Russell K. Yamazaki
Abstract 131
Introduction 132
Mechanism and Function of Py Phosphorylation by CdkS 132
Protein Kinases for Py Phosphorylation 136
Previous Studies Suggesting PDE Regulation by Py Phosphorylation and
Turnoff of GTP/Toc Activated PDE without GTP Hydrolysis 143
Regulation by Ca2+ or Ca2+ Binding Protein of Py Phosphorylation
by Cdk5 Preliminary Studies 146
Conclusions 148
10. CENTRINS, A NOVEL GROUP OF Ca2+ BINDING PROTEINS
IN VERTEBRATE PHOTORECEPTOR CELLS 155
Uwe Wolfrum, Andreas GieBl, Alexander Pulvermuller
Abstract 155
Introduction 155
What are Centrins? 158
Centrin Genes and Molecular Structure of Centrin Proteins 158
Centrin s Cellular Localization and Function 162
Centrins in the Vertebrate Retina 163
Centrin Functions as a Cytoskeletal Component the Connecting Cilium
of the Photoreceptor Cell 164
Centrin Interacting Proteins in Mammalian Photoreceptor Cells 167
Centrin/Transducin Complex 168
Conclusion 1
xviii Contents
11. TUNING OUTER SEGMENT Ca2+ HOMEOSTASIS TO
PHOTOTRANSDUCTION IN RODS AND CONES 179
Juan I. Korenbrot and Tatiana I. Rebrik
Abstract 179
The Fraction of the Dark Current Carried by Ca2+ through cGMP Gated
Ion Channels is Higher in Cones than in Rods 181
The Maximum Rate of Outer Segment Ca2+ Clearance is Higher in Cones
than in Rods 186
In Intact Photoreceptors Cone CNG Channels, but Not Rod CNG Channels,
Demonstrate a Large Ca2+ Dependent Modulation in Their Cyclic Nucle
otide Sensitivity 188
Functional Consequence of Rod Cone Differences in Ca2+ Homeostasis 192
12. REGULATION OF THE ROD PHOTORECEPTOR
CYCLIC NUCLEOTIDE GATED CHANNEL 205
Rene Warren and Robert S. Molday
Abstract 205
Introduction 205
Rod CNG Channel—Structural Features 207
Regulation of the Rod Channel 210
Interaction of the Rod Channel with Other ROS Membrane Proteins 219
Conclusions 219
13. Ca2+ CHANNELS IN THE RPE 225
Rita Rosenthal and Olaf StrauB
Summary 225
The Retinal Pigment Epithelium 226
Ca2+ Channels in the RPE 226
The Regulation of L Type Channels 228
Involvement of L Type Channels in Intracellular Signalling Systems 228
L Type Channels and Retinal Degeneration 229
The Physiological Role of L Type Channels in the Retinal Pigment Epithelium 231
14. THE RETINAL ROD AND CONE Na7Ca2+ K+ EXCHANGERS 237
Clemens F.M. Prinsen, Conan B. Cooper, Robert T. Szerencsei,
Sabita K. Murthy, Douglas J. Demetrick and Paul P.M. Schnetkamp
Abstract 237
Introduction 238
Functional Characteristics of in Situ Rod NCKX 238
Intraretinal Localization of the Human Retinal Rod and Cone
Na7Ca2+ K+ Exchangers 241
Chromosomal Localization of the Human Retinal Rod and Cone
Na7Ca2+ K+ Exchangers 243
Contents xjx
Analysis of the Rod and Cone Na7Ca24 K* Exchanger Sequences 243
Functional Characterization of Heterologously Expressed Rod
and Cone NCKX 247
15. THE COMPLEX OF cGMP GATED CHANNEL AND Na7Ca2+,K+
EXCHANGER IN ROD PHOTORECEPTORS 253
Paul J. Bauer
Abstract 253
Introduction 253
Channel and Na7Ca2+, K+ Exchanger Reside Only in the Plasma Membrane 256
The Density of cGMP Gated Channels 257
The Density of Na7Ca2+, K+ Exchangers: An Intriguing Problem 259
Interaction Between Solubilized Channel and Exchanger 260
Association of Channel and Exchanger in the Plasma Membrane 261
Different Subunit Arrangements of the Channel Entail Different
Quaternary Structures 263
Self Inhibition of the Exchanger—An Allosteric Regulatory Mechanism? 266
Local Ca2+ Signaling in Photoreceptors 266
Conclusion and Outlook 268
16. REGULATION OF VOLTAGE SENSITIVE Ca2+ CHANNELS
IN BIPOLAR CELLS BY DIVALENT CATIONS
AND POLYAMINES 275
Eric M. Lasater and Eduardo Solessio
Abstract 275
Introduction 276
Methods 276
Results 277
Conclusion 284
17. SITE DIRECTED AND NATURAL MUTATIONS IN STUDYING
FUNCTIONAL DOMAINS IN GUANYLYL CYCLASE
ACTIVATING PROTEINS (GCAPs) 291
Alexander Dizhoor
Abstract 291
Introduction 292
Mutations in Ca Binding Domains in GCAP 1 and GCAP 2 293
Mutations that Affect the N Fatty Acylation 294
Functional Regions in GCAPs that Contribute to the retGC Activation
or Inhibition 294
Mutations in GCAP 2 that Affect its Dimerization 296
Naturally Occurring Mutations in GCAP 1 Associated with
Cone Degeneration 297
xx Contents
18. CALMODULIN AND Ca2+ BINDING PROTEINS (CaBPs):
VARIATIONS ON A THEME 303
Francoise Haeseleer and Krzysztof Palczewski
Abstract 303
Introduction 303
Ca2t Signaling in the Retina 304
EF hand Motif containing Ca2+ Binding Proteins Expressed in the Retina 305
CaBPs 307
19. GCAPs: Ca2+ SENSITIVE REGULATORS OF retGC 319
Wqjciech A. Gorczycal, and Izabela Sokal
Abstract 319
Introduction 319
Discovery of GCAPs 320
Structure and Properties of GCAPs 321
Purification of GCAPs from the Retina 323
Localization of GCAPs 324
Ca2M)ependent Regulation of retGC Activity by GCAPs 326
Closing Remarks 328
20. STRUCTURE AND MEMBRANE TARGETING MECHANISM
OF RETINAL Ca2+ BINDING PROTEINS, RECOVERIN
ANDGCAP 2 333
James B. Ames and Mitsuhiko Ikura
Abstract 333
Introduction 333
Three Dimensional Structures of Recoverin 334
Structure of a Recoverin Mutant (E85Q) in an Allosteric Intermediate State 336
Mechanism of the Ca2+ Myristoyl Switch 342
Three Dimensional Structure of GCAP 2 343
21. TARGET RECOGNITION OF GUANYLATE CYCLASE BY
GUANYLATE CYCLASE ACTIVATING PROTEINS 349
Karl Wilhelm Koch
Abstract 349
Introduction 349
Complex of Guanylate Cyclase and GCAP 350
Crosslinking of GCAP 1 350
Interaction of Guanylate Cyclases and GCAPs at Low and High [Ca2*] 352
Contents X i
Target Regions in ROS GC1 353
Apparent Affinities of Target Regions in ROS GC1 353
Model of GCAP 1 Mediated Activation of ROS GC1 355
Physiological Significance of a Permanent ROS GC1/GCAP 1 Complex 355
Affinities of GCAP 1 for Ca2+ 355
Dimerization of ROS GC1 356
Conclusion 356
22. MOUSE MODELS TO STUDY GCAP FUNCTIONS
IN INTACT PHOTORECEPTORS 361
Ana Mendez and Jeannie Chen
Abstract 361
Introduction 361
Functions of the GCAP Proteins in Intact Photoreceptors: Effects of the
Ca2+ Feedback to Ret GCs on the Light Response 364
Effect of Restoring GCAP2 in GCAPs / Photoreceptors 372
GCAPs and Disease: Mouse Models Expressing Forms of GCAPs with Impaired
Ca2+ Binding Properties 377
Conclusion 383
23. CALCIUM DEPENDENT ACTIVATION OF GUANYLATE
CYCLASE BY SlOOb 389
Ari Sitaramayya
Abstract 389
Introduction 390
Detection of High Calcium Activator in Crude Retinal Extract 391
Purification of the Factor Responsible for Activation at High
Calcium Concentration 391
Dose and Calcium Dependence of the Activation 392
Identification of CD GCAP as SlOOb 395
The Significance of Cyclase Activation by SlOOb 395
24. THE ROLE OF CADHERINS IN Ca2+ MEDIATED
CELL ADHESION AND INHERITED
PHOTORECEPTOR DEGENERATION 399
Hanno Bolz, Jan Reiners, Uwe Wolfrum and Andreas Gal
Cadherins: Features and Functions 399
Role of Cadherins in Human Disease 403
Role of Cadherins in Human Retina 403
Conclusion 408
xxjj Contents
25. GUANYLATE CYCLASE ACTIVATING PROTEINS,
GUANYLATE CYCLASE AND DISEASE 411
Richard J. Newbold, Evelyne C. Deery, Annette M. Payne,
Susan E. Wilkie, David M. Hunt and Martin J. Warren
Abstract 411
Introduction 412
RetGCl and Retinal Disease 414
RetGCl s Role in Cone and Cone Rod Dystrophies 415
GCAP1 and Retinal Disease 422
Analysis and Discussion of the Effects of GCAP1 Mutations 423
Conclusion 431
26. USING MUTANT MICE TO STUDY THE ROLE
OF VOLTAGE GATED CALCIUM CHANNELS
IN THE RETINA 439
Sherry L. Ball and Ronald G. Gregg
Abstract 439
Introduction 440
Neuronal Ca2+ Channels 440
Assessment of Retinal Function in Mutant Mice 442
Impact of VGCC Subunit Mutations on Retinal Function 442
Conclusions and Future Directions 448
27. CALDENDRINS IN THE INNER RETINA 451
Constanze I. Seidenbecher, C. Reissner and Michael R. Kreutz
Abstract 451
Introduction 451
The Molecular Structure of Caldendrin 453
Biochemical Features of Caldendrin 456
Distribution of Caldendrin in the Forebrain 456
Distribution of Caldendrin in the Retina 457
Comparison with other CaBPs 458
Caldendrin Localization at Synapses 459
Caldendrin Expression During Retinal Development 460
Is There a Specific Function for Caldendrin in Dendritic Ca2+ Signaling? 461
28. CALCIUM CHANNELS AT THE PHOTORECEPTOR SYNAPSE ... 465
Steven Barnes and Melanie E.M. Kelly
Abstract 465
Introduction 465
Contents xxiii
Voltage Gated Ca2+ Channels at the Presynaptic Terminals
of the Photoreceptors 467
Other Ca2+ Permeable Channels in the Photoreceptor Terminals 464
The Role of Ca2+ Permeable Channels in Feedback from Second Order Cells 474
Conclusion 473
29. ON BIPOLAR CELLS: FOLLOWING IN THE FOOTSTEPS
OF PHOTOTRANSDUCTION 477
Malcolm M. Slaughter and Gautam B. Awatramani
Abstract 477
Introduction 477
Signal Transduction at the ON Bipolar Cell Synapse 478
A Note about Methods 478
The ON Bipolar Cell s Synaptic Receptors 479
Two Types of Bipolar Cells: Fidelity at the Synapse 480
Transient and Sustained Responses in Ganglion Cells 481
Transient and Sustained Bipolar Cells 483
Does Calcium Influence Transient Signals? 488
Different Bipolar Cells Drive Transient and Sustained Ganglion Cells 490
Conclusion 490
30. Ca2+ REGULATION OF DROSOPHILA
PHOTOTRANSDUCTION 493
Joseph E. O Tousa
Abstract 493
Introduction 493
Ca2+ Control of the Rhodopsin Photocycle 494
Ca2+ Regulation of Intermediate Steps of the Phototransduction Cascade 497
Ca27Calmodulin Control of the Light Gated TRP and TRPL Channels 501
Summary 501
31. SIMULTANEOUS ROLES FOR Ca2+ IN EXCITATION
AND ADAPTATION OF LIMULUS
VENTRAL PHOTORECEPTORS 507
John E. Lisman, Edwin A. Richard, Sridhar Raghavachari and Richard Payne
Abstract 507
Abbreviations 508
Introduction 508
Mechanisms for Changes in Intracellular Ca2+ 510
Role of Ca2* in Excitation 520
Intracellular Ca2+ Elevation Produces Light Adaptation 527
Summary 530
xxjv Contents
32. CALCIUM HOMEOSTASIS IN FLY
PHOTORECEPTOR CELLS 539
Johannes Oberwinkler
Abstract 539
Introduction 540
The Special Anatomy of the Fly Photoreceptor Cells 541
Physiological and Molecular Components Involved in Calcium Homeostasis 545
Form and Function of the Calcium Signals 553
The Molecular Targets of Calcium Feedback in the Microvilli 563
Calcium Signals in the Photoreceptor Cells of Another Insect,
the Honeybee Drone 570
Conclusions and Outlook 572
33. PHOTORECEPTOR DEGENERATION AND Ca2t
INFLUX THROUGH LIGHT ACTIVATED
CHANNELS OF DROSOPHILA 585
Chaoxian Geng and William L. Pak
Abstract 585
Invertebrate Phototransduction 585
Ca1* Entry through TRPand TRPL Channels 587
Magnitude of Ca Entry and Photoreceptor Degeneration 587
Degeneration Caused by Constitutive Activity of the TRP Channel 588
Conclusion 596
34. THE TRP CALCIUM CHANNEL AND
RETINAL DEGENERATION 601
Baruch Minke
Abstract ..„ „ ..601
Introduction „ „......„ ...601
The Drosophila TRP and TRPL Channels „ „ „ 602
The TRP Family of Channel Proteins 604
Constitutive Activity of the TRP Channel by Mutations and by Metabolic
Stress May Underlie Retinal Degeneration „ 607
Conclusion „..„ „..„ „ _„...._ „ 618
INDEX ..„ „ „ „ 623
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| dewey-full | 573.8/828 |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV014832006 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:07:46Z |
| institution | BVB |
| isbn | 0306474158 |
| language | English |
| lccn | 2002040771 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010036391 |
| oclc_num | 50803937 |
| open_access_boolean | |
| owner | DE-12 DE-19 DE-BY-UBM |
| owner_facet | DE-12 DE-19 DE-BY-UBM |
| physical | XXIV, 625 S. Ill., graph. Darst |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | Kluwer Acad., Plenum Publ. [u.a.] |
| record_format | marc |
| series | Advances in experimental medicine and biology |
| series2 | Advances in experimental medicine and biology |
| spelling | Photoreceptors and calcium ed. by Wolfgang Baehr ; Krzysztof Palczewski New York [u.a.] Kluwer Acad., Plenum Publ. [u.a.] 2002 XXIV, 625 S. Ill., graph. Darst txt rdacontent n rdamedia nc rdacarrier Advances in experimental medicine and biology 514 Includes bibliographical references and index Calciprotéines - Effets physiologiques Calcium - Effets physiologiques Canaux à calcium Rétine Œil - Aspect moléculaire Calcium channels Calcium Physiological effect Calcium metabolism Calcium-Binding Proteins Calcium-binding proteins Physiological effect Eye Molecular aspects Light Signal Transduction Photoreceptor Cells, Vertebrate Retina Calcium (DE-588)4069806-3 gnd rswk-swf Photorezeptor (DE-588)4045934-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Photorezeptor (DE-588)4045934-2 s Calcium (DE-588)4069806-3 s DE-604 Baehr, Wolfgang Sonstige oth Palczewski, Krzysztof Sonstige oth Advances in experimental medicine and biology 514 (DE-604)BV000003102 514 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010036391&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Photoreceptors and calcium Advances in experimental medicine and biology Calciprotéines - Effets physiologiques Calcium - Effets physiologiques Canaux à calcium Rétine Œil - Aspect moléculaire Calcium channels Calcium Physiological effect Calcium metabolism Calcium-Binding Proteins Calcium-binding proteins Physiological effect Eye Molecular aspects Light Signal Transduction Photoreceptor Cells, Vertebrate Retina Calcium (DE-588)4069806-3 gnd Photorezeptor (DE-588)4045934-2 gnd |
| subject_GND | (DE-588)4069806-3 (DE-588)4045934-2 (DE-588)4143413-4 |
| title | Photoreceptors and calcium |
| title_auth | Photoreceptors and calcium |
| title_exact_search | Photoreceptors and calcium |
| title_full | Photoreceptors and calcium ed. by Wolfgang Baehr ; Krzysztof Palczewski |
| title_fullStr | Photoreceptors and calcium ed. by Wolfgang Baehr ; Krzysztof Palczewski |
| title_full_unstemmed | Photoreceptors and calcium ed. by Wolfgang Baehr ; Krzysztof Palczewski |
| title_short | Photoreceptors and calcium |
| title_sort | photoreceptors and calcium |
| topic | Calciprotéines - Effets physiologiques Calcium - Effets physiologiques Canaux à calcium Rétine Œil - Aspect moléculaire Calcium channels Calcium Physiological effect Calcium metabolism Calcium-Binding Proteins Calcium-binding proteins Physiological effect Eye Molecular aspects Light Signal Transduction Photoreceptor Cells, Vertebrate Retina Calcium (DE-588)4069806-3 gnd Photorezeptor (DE-588)4045934-2 gnd |
| topic_facet | Calciprotéines - Effets physiologiques Calcium - Effets physiologiques Canaux à calcium Rétine Œil - Aspect moléculaire Calcium channels Calcium Physiological effect Calcium metabolism Calcium-Binding Proteins Calcium-binding proteins Physiological effect Eye Molecular aspects Light Signal Transduction Photoreceptor Cells, Vertebrate Retina Calcium Photorezeptor Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010036391&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000003102 |
| work_keys_str_mv | AT baehrwolfgang photoreceptorsandcalcium AT palczewskikrzysztof photoreceptorsandcalcium |