Molecular genetics of bacteria:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Washington, D.C.
ASM Press
2003
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XVI, 566 S. Ill., graph. Darst. |
| ISBN: | 155581204X |
Internformat
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| 100 | 1 | |a Snyder, Larry |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Molecular genetics of bacteria |c Larry Snyder and Wendy Champness |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Washington, D.C. |b ASM Press |c 2003 | |
| 300 | |a XVI, 566 S. |b Ill., graph. Darst. | ||
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| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Bactériophages - Génétique | |
| 650 | 7 | |a Genética bacteriana |2 larpcal | |
| 650 | 7 | |a Genética molecular |2 larpcal | |
| 650 | 4 | |a Génétique bactérienne | |
| 650 | 4 | |a Génétique moléculaire | |
| 650 | 4 | |a Bacteria |x genetics | |
| 650 | 4 | |a Bacterial genetics | |
| 650 | 4 | |a Bacteriophages |x Genetics | |
| 650 | 4 | |a Bacteriophages |x genetics | |
| 650 | 4 | |a Chromosomes, Bacterial | |
| 650 | 4 | |a Genetics, Microbial |x methods | |
| 650 | 4 | |a Molecular Biology |x methods | |
| 650 | 4 | |a Molecular genetics | |
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Datensatz im Suchindex
| _version_ | 1804129288478261248 |
|---|---|
| adam_text | SECOND EDITION MOLECULAR GENETICS OF BACTERIA LARRY SNYDER AND WENDY
CHAMPNESS DEPARTMENT OF MICROBIOLOGY AND MOLECULAR GENETICS MICHIGAN
STATE UNIVERSITY EAST LANSING, MICHIGAN ASM PRESS WASHINGTON, D.C.
CONTENTS BOXES XIII PREFACE XV INTRODUCTION 1 THE BIOLOGICAL UNIVERSE 2
THE EUBACTERIA 2 THE ARCHAEA 4 THE EUKARYOTES 4 THE PROKARYOTES AND THE
EUKARYOTES WHAT IS GENETICS? 5 BACTERIAL GENETICS 5 BACTERIA ARE HAPLOID
5 SHORT GENERATION TIMES 5 ASEXUAL REPRODUCTION 6 COLONY GROWTH ON AGAR
PLATES 6 COLONY PURIFICATION 6 SERIAL DILUTIONS 6 SELECTIONS 6 STORING
STOCKS OF BACTERIAL STRAINS 6 GENETIC EXCHANGE 7 PHAGE GENETICS 7 PHAGES
ARE HAPLOID 7 SELECTIONS WITH PHAGES 7 CROSSES WITH PHAGES 7 CONTENTS A
BRIEF HISTORY OF BACTERIAL MOLECULAR GENETICS 7 INHERITANCE IN BACTERIA
8 TRANSFORMATION 8 CONJUGATION 8 TRANSDUCTION 8 RECOMBINATION WITHIN
GENES 8 SEMICONSERVATIVE DNA REPLICATION 9 MRNA 9 GENETIC CODE 9 THE
OPERON MODEL 9 ENZYMES FOR MOLECULAR BIOLOGY 9 WHAT S AHEAD 9 SUGGESTED
READING 10 PART § GENES: REPLICATION AND EXPRESSION 11 CHAPTER 1
MACROMOLECULAR SYNTHESIS: CHROMOSOME STRUCTURE, REPLICATION, AND
SEGREGATION DNA STRUCTURE 13 THE DEOXYRIBONUCLEOTIDES 13 THE DNA CHAIN
14 THE 5 AND 3 ENDS 14 BASE PAIRING 14 ANTIPARALLEL CONSTRUCTION 16 THE
MAJOR AND MINOR GROOVES 16 MECHANISM OF DNA REPLICATION 17
DEOXYRIBONUCLEOTIDE PRECURSOR SYNTHESIS 17 DEOXYNUCLEOTIDE
POLYMERIZATION 17 SEMICONSERVATIVE REPLICATION 19 REPLICATION OF
DOUBLE-STRANDED DNA 21 REPLICATION ERRORS 24 EDITING 26 METHYL-DIRECTED
MISMATCH REPAIR 27 ROLE OF EDITING AND MISMATCH REPAIR IN MAINTAINING
REPLICATION FIDELITY 27 REPLICATION OF THE BACTERIAL CHROMOSOME AND CELL
DIVISION 28 STRUCTURE OF THE BACTERIAL CHROMOSOME 28 REPLICATION OF THE
BACTERIAL CHROMOSOME 29 INITIATION OF CHROMOSOME REPLICATION 29 13
TERMINATION OF CHROMOSOME REPLICATION 30 SEGREGATION OF THE TWO DAUGHTER
DNAS AFTER REPLICATION 32 PARTITIONING OF THE CHROMOSOME AFTER
REPLICATION WHERE ARE THE REPLICATION FORKS? 37 CELL DIVISION 37
COORDINATION OF CELL DIVISION WITH REPLICATION OF THE CHROMOSOME 38
TIMING OF INITIATION OF REPLICATION 40 35 SUPERCOILING 41 THE BACTERIAL
NUCLEOID 41 SUPERCOILING IN THE NUCLEOID TOPOISOMERASES 43 42
ANTIBIOTICS THAT AFFECT REPLICATION AND DNA STRUCTURE 45 ANTIBIOTICS
THAT BLOCK PRECURSOR SYNTHESIS 45 ANTIBIOTICS THAT BLOCK POLYMERIZATION
OF NUCLEOTIDES 45 ANTIBIOTICS THAT AFFECT DNA STRUCTURE 46 ANTIBIOTICS
THAT AFFECT GYRASE 46 MOLECULAR BIOLOGY MANIPULATIONS WITH DNA 46
RESTRICTION ENDONUCLEASES 46 HYBRIDIZATIONS 49 APPLICATIONS OF THE
ENZYMES USED IN DNA REPLICATION 52 SUMMARY 58 QUESTIONS FOR THOUGHT 59
PROBLEMS 59 SUGGESTED READING 60 CHAPTER 2 MACROMOLECULAR SYNTHESIS:
GENE EXPRESSION 61 OVERVIEW 61 THE STRUCTURE AND FUNCTION OF RNA 62
TYPES OF RNA 62 RNA PRECURSORS 62 RNA STRUCTURE 63 RNA PROCESSING AND
MODIFICATION 65 TRANSCRIPTION 65 BACTERIAL- RNA POLYMERASE 65
TRANSCRIPTION INITIATION 65 THE POLYMERIZATION REACTION 68 TRANSCRIPTION
TERMINATION 70 RRNAS AND TRNAS AND THEIR SYNTHESIS 72 CONTENTS PROTEINS
73 PROTEIN STRUCTURE 73 TRANSLATION 75 DETAILS OF PROTEIN SYNTHESIS 75
THE GENETIC CODE 81 TRANSLATION INITIATION 83 TRANSLATION TERMINATION 86
POLYCISTRONIC MRNA 86 PROTEIN FOLDING 89 CHAPERONES 89 MEMBRANE PROTEINS
AND PROTEIN EXPORT THE TARGETING FACTORS 91 PROTEIN SECRETION 93
DISULFIDE BONDS 94 REGULATION OF GENE EXPRESSION 94 USEFUL CONCEPTS 97
OPEN READING FRAME 99 TRANSCRIPTIONAL AND TRANSLATIONAL FUSIONS
ANTIBIOTICS THAT BLOCK TRANSCRIPTION AND TRANSLATION 102 ANTIBIOTIC
INHIBITORS OF TRANSCRIPTION 102 ANTIBIOTIC INHIBITORS OF TRANSLATION 103
SUMMARY 106 QUESTIONS FOR THOUGHT 108 PROBLEMS 108 SUGGESTED READING 109
91 100 PART SI GENES AND GENETIC ELEMENTS 111 CHAPTER 3 MUTATIONS AND
GENETIC ANALYSIS 113 DEFINITIONS 113 TERMS USED IN GENETICS 113 GENETIC
NAMES 114 USEFUL PHENOTYPES IN BACTERIAL GENETICS 115 AUXOTROPHIC
MUTANTS 115 CONDITIONAL LETHAL MUTANTS 116 RESISTANT MUTANTS 117
INHERITANCE IN BACTERIA 117 THE LURIA AND DELBRIICK EXPERIMENT 118 THE
NEWCOMBE EXPERIMENT 121 THE LEDERBERGS EXPERIMENT 123 MUTATION RATES
123 CALCULATING MUTATION RATES 123 USING THE INCREASE IN THE FRACTION OF
MUTANTS TO MEASURE MUTATION RATES 125 SUMMARY 126 TYPES OF MUTATIONS 126
BASE PAIR CHANGES 127 FRAMESHIFT MUTATIONS 131 DELETION MUTATIONS 132
INVERSION MUTATIONS 133 TANDEM DUPLICATION MUTATIONS 135 INSERTION
MUTATIONS 135 REVERSION VERSUS SUPPRESSION 136 INTRAGENIC SUPPRESSORS
136 INTERGENIC SUPPRESSORS 136 NONSENSE SUPPRESSORS 137 GENETIC ANALYSIS
139 ISOLATING MUTANTS 140 ISOLATING INDEPENDENT MUTATIONS 140 SELECTING
MUTANTS 141 REPLICA PLATING 142 ENRICHMENT 142 COMPLEMENTATION 143
RECOMBINATION TESTS 145 GENE REPLACEMENTS AND TRANSGENICS 148 SUMMARY
154 QUESTIONS FOR THOUGHT 155 PROBLEMS 155 SUGGESTED READING 156 CHAPTER
4 PLASMIDS 157 WHAT IS A PLASMID? 157 NAMING PLASMIDS 157 FUNCTIONS
ENCODED BY PLASMIDS 159 PLASMID STRUCTURE 159 PROPERTIES OF PLASMIDS 161
REPLICATION 161 FUNCTIONS OF THE OH REGION 165 MECHANISMS TO PREVENT
CURING OF PLASMIDS 1 72 THE PAR SYSTEMS 1 74 INCOMPATIBILITY 1 76
MAINTAINING PLASMIDS BELONGING TO THE SAME INCOMPATIBILITY GROUP 178
CONTENTS CONSTRUCTING A PLASMID CLONING VECTOR 179 FINDING THE PLASMID
ORI REGION 179 EXAMPLES OF PLASMID CLONING VECTORS 180 BROAD-HOST-RANGE
CLONING VECTORS 183 SUMMARY 184 QUESTIONS FOR THOUGHT 185 PROBLEMS 185
SUGGESTED READING 185 CHAPTER 5 CONJUGATION 187 OVERVIEW 187
CLASSIFICATION OF SELF-TRANSMISSIBLE PLASMIDS 188 INTERSPECIES TRANSFER
OF PLASMIDS 188 MECHANISM OF DNA TRANSFER DURING CONJUGATION IN
GRAM-NEGATIVE BACTERIA 189 TRANSFER (TRA) GENES 192 THE ORIT SEQUENCE
197 EFFICIENCY OF TRANSFER 197 MOBILIZABLE PLASMIDS 198 CHROMOSOME
TRANSFER BY PLASMIDS 201 FORMATION OF HFR STRAINS 202 TRANSFER OF
CHROMOSOMAL DNA BY INTEGRATED PLASMIDS 202 GENETIC MAPPING WITH HFR
CROSSES 204 GENETIC MARKERS 204 ANALYSIS OF HFR CROSSES 205 CHROMOSOME
MOBILIZATION 207 CHAPTER 6 TRANSFORMATION 217 PRIME FACTORS 207 CREATION
OF PRIME FACTORS 208 COMPLEMENTATION TESTS USING PRIME FACTORS ROLE OF
PRIME FACTORS IN EVOLUTION 210 TRANSFER SYSTEMS OF GRAM-POSITIVE
BACTERIA 210 PLASMID-ATTRACTING PHEROMONES 210 OTHER TYPES OF
TRANSMISSIBLE ELEMENTS 214 SUMMARY 214 QUESTIONS FOR THOUGHT 215
PROBLEMS 215 SUGGESTED READING 216 208 NATURAL TRANSFORMATION 217
DISCOVERY OF TRANSFORMATION 218 COMPETENCE 218 UPTAKE OF DNA DURING
NATURAL TRANSFORMATION 221 MECHANISM OF DNA UPTAKE DURING TRANSFORMATION
222 GENETIC EVIDENCE FOR SINGLE-STRAND UPTAKE 223 PLASMID TRANSFORMATION
AND TRANSFECTION OF NATURALLY COMPETENT BACTERIA 223 THE ROLE OF NATURAL
TRANSFORMATION 224 ARTIFICIALLY INDUCED COMPETENCE 226 CALCIUM ION
INDUCTION 226 ELECTROPORATION 228 SUMMARY 228 QUESTIONS FOR THOUGHT 229
PROBLEMS 229 SUGGESTED READING 229 CHAPTER 7 LYTIC BACTERIOPHAGES:
GENETIC ANALYSIS AND USE IN TRANSDUCTION 231 BACTERIOPHAGE LYTIC
DEVELOPMENT CYCLE 233 PHAGE T7: A PHAGE-ENCODED RNA POLYMERASE 234 PHAGE
T4: TRANSCRIPTIONAL ACTIVATORS, ANTITERMINATION, A NEW SIGMA FACTOR, AND
REPLICATION-COUPLED TRANSCRIPTION 237 PHAGE DNA REPLICATION 242 PHAGES
WITH SINGLE-STRANDED CIRCULAR DNA 243 PHAGE T7: LINEAR DNA THAT FORMS
CONCATEMERS 249 PHAGE T4: ANOTHER LINEAR DNA THAT FORMS CONCATEMERS 250
GENETIC ANALYSIS OF PHAGES 252 INFECTION OF CELLS 253 PHAGE CROSSES 253
RECOMBINATION AND COMPLEMENTATION TESTS WITH PHAGES 254 EXPERIMENTS WITH
THE RLL GENES OF PHAGE T4 256 CONSTRUCTING THE GENETIC LINKAGE MAP OF A
PHAGE 263 CONTENTS GENERALIZED TRANSDUCTION 267 WHAT MAKES A TRANSDUCING
PHAGE? 268 MAPPING OF BACTERIAL MARKERS BY TRANSDUCTION 269 THE ROLE OF
TRANSDUCTION IN BACTERIAL EVOLUTION 272 SUMMARY 272 QUESTIONS FOR
THOUGHT 273 PROBLEMS 273 SUGGESTED READING 274 CHAPTER 8 PHAGE X AND
LYSOGENY 275 PHAGE A, 276 PHAGE X: LYTIC DEVELOPMENT 276 PHAGE X: LINEAR
DNA THAT REPLICATES AS A CIRCLE 281 LYSOGENY 282 THE DL GENE PRODUCT 282
PHAGE X INTEGRATION 283 MAINTENANCE OF LYSOGENY 285 REGULATION OF
REPRESSOR SYNTHESIS IN THE LYSOGENIC STATE 285 IMMUNITY TO
SUPERINFECTION 286 THE INDUCTION OF X 286 COMPETITION BETWEEN THE LYTIC
AND LYSOGENIC CYCLES 287 SPECIALIZED TRANSDUCTION 290 OTHER LYSOGENIC
PHAGES 291 PHAGE P2 291 PHAGE P4 291 PHAGE P1: A PLASMID PROPHAGE 293
PHAGE MU 294 USE OF LYSOGENIC PHAGES AS CLONING VECTORS 294 LYSOGENIC
PHAGES AND BACTERIAL PATHOGENESIS 294 E. COLI AND DYSENTERY: SHIGA
TOXINS 294 DIPHTHERIA 295 CHOLERA 295 BOTULISM AND TETANUS 296 SYNOPSIS
296 GENETIC EXPERIMENTS WITH PHAGE A, 296 GENETICS OF X LYSOGENY 296
GENETICS OF THE CL REPRESSOR 297 ISOLATION OF X NUT MUTATIONS 297
ISOLATION OF HOST NUS MUTATIONS 300 SUMMARY 300 QUESTIONS FOR THOUGHT
301 PROBLEMS 302 SUGGESTED READING 302 CHAPTER 9 TRANSPOSITION AND
SITE-SPECIFIC RECOMBINATION 303 TRANSPOSITION 303 OVERVIEW OF
TRANSPOSITION 304 STRUCTURE OF BACTERIAL TRANSPOSONS 304 TYPES OF
BACTERIAL TRANSPOSONS 305 ASSAYS OF TRANSPOSITION 308 GENETIC
REQUIREMENTS FOR TRANSPOSITION 310 MOLECULAR MODELS FOR TRANSPOSITION
314 TRANSPOSON MUTAGENESIS 319 TRANSPOSON MUTAGENESIS OF PLASMIDS 320
TRANSPOSON MUTAGENESIS OF THE BACTERIAL CHROMOSOME 325 TRANSPOSON
MUTAGENESIS OF ALL BACTERIA 328 USING TRANSPOSON MUTAGENESIS TO MAKE
RANDOM GENE FUSIONS 329 IN VIVO CLONING 332 SITE-SPECIFIC RECOMBINATION
333 DEVELOPMENTALLY REGULATED EXCISION OF INTERVENING DNA 333 INTEGRASES
334 RESOLVASES 336 DNA INVERTASES 336 TOPOISOMERASES 338 SUMMARY 338
QUESTIONS FOR THOUGHT 339 PROBLEMS 339 SUGGESTED READING 340 PART III
GENES IN ACTION 341 CHAPTER 10 MOLECULAR BASIS OF RECOMBINATION 343
OVERVIEW OF RECOMBINATION 344 REQUIREMENT 1: IDENTICAL OR VERY SIMILAR
SEQUENCES IN THE CROSSOVER REGION 344 CONTENTS REQUIREMENT 2:
COMPLEMENTARY BASE PAIRING BETWEEN DOUBLE-STRANDED DNA MOLECULES 344
REQUIREMENT 3: RECOMBINATION ENZYMES 344 REQUIREMENT 4: HETERODUPLEX
FORMATION 345 MOLECULAR MODELS OF RECOMBINATION 345 THE HOLLIDAY
DOUBLE-STRAND INVASION MODEL 345 SINGLE-STRAND INVASION MODEL 346
DOUBLE-STRAND BREAK REPAIR MODEL 347 MOLECULAR BASIS FOR RECOMBINATION
IN E. COLI 349 CHI (X) SITES AND THE RECBCD NUCLEASE 349 THE RECF
PATHWAY 352 SYNAPSE FORMATION AND THE RECA PROTEIN 353 THE RUV AND RECG
PROTEINS AND THE MIGRATION AND CUTTING OF HOLLIDAY JUNCTIONS 354 PHAGE
RECOMBINATION PATHWAYS 358 REC PROTEINS OF PHAGES T4 AND T7 358 THE RECE
PATHWAY OF THE RAC PROPHAGE 358 THE PHAGE X RED SYSTEM 358 GENETIC
ANALYSIS OF RECOMBINATION IN BACTERIA 358 ISOLATING REC MUTANTS OF E.
COLI 358 OTHER RECOMBINATION GENES 362 GENE CONVERSION AND OTHER
MANIFESTATIONS OF HETERODUPLEX FORMATION DURING RECOMBINATION 364
SUMMARY 366 QUESTIONS FOR THOUGHT 367 PROBLEMS 367 SUGGESTED READING 368
CHAPTER 11 DNA REPAIR AND MUTAGENESIS 369 EVIDENCE FOR DNA REPAIR 370
SPECIFIC REPAIR PATHWAYS 371 DEAMINATION OF BASES 371 DAMAGE DUE TO
REACTIVE OXYGEN 374 ALKYLATION 377 PYRIMIDINE DIMERS 379 GENERAL REPAIR
MECHANISMS 380 THE METHYL-DIRECTED MISMATCH REPAIR SYSTEM NUCLEOTIDE
EXCISION REPAIR 385 RECOMBINATION REPAIR 387 380 SOS INDUCIBLE REPAIR
389 OTHER DIN GENES 395 SUMMARY OF REPAIR PATHWAYS IN E. COLI 396
BACTERIOPHAGE REPAIR PATHWAYS 396 GENETIC ANALYSIS OF REPAIR PATHWAYS
398 SUMMARY 400 QUESTIONS FOR THOUGHT 401 PROBLEMS 401 SUGGESTED READING
402 CHAPTER 12 REGULATION OF GENE EXPRESSION 403 TRANSCRIPTIONAL
REGULATION IN BACTERIA 404 GENETIC EVIDENCE FOR NEGATIVE AND POSITIVE
REGULATION 404 NEGATIVE REGULATION 406 THE COLI LAC OPERON 406 THE E.
COLI GAL OPERON 412 REGULATION OF BIOSYNTHETIC OPERONS: APOREPRESSORS
AND COREPRESSORS 416 POSITIVE REGULATION 418 THE E. COLI L-ARA OPERO N
418 THE COLI MALTOSE OPERONS 422 THE TOL OPERONS 424 REGULATION BY
ATTENUATION OF TRANSCRIPTION 426 GENETIC EVIDENCE FOR ATTENUATION 429
FEEDBACK INHIBITION 432 TRYPTOPHAN OPERON 432 ISOLEUCINE-VALINE OPERON
432 SUMMARY 432 QUESTIONS FOR THOUGHT 433 PROBLEMS 433 SUGGESTED READING
434 CHAPTER 13 GLOBAL REGULATORY MECHANISMS 435 CATABOLITE-SENSITIVE
OPERONS 436 CAMP AND THE CAMP-BINDING PROTEIN 436 GENETIC ANALYSIS OF
CATABOLITE REGULATION IN COLI 440 USES OF CAMP IN OTHER ORGANISMS 442
CONTENTS REGULATION OF NITROGEN ASSIMILATION 442 PATHWAYS FOR NITROGEN
ASSIMILATION 444 COORDINATION OF CATABOLITE REPRESSION, THE NTR SYSTEM,
AND THE REGULATION OF AMINO ACID DEGRADATIVE OPERONS 453 GENETIC
ANALYSIS OF NITROGEN REGULATION IN ENTERIC BACTERIA 453 REGULATION OF
PORIN SYNTHESIS 454 GENETIC ANALYSIS OF PORIN REGULATION 455 REGULATION
OF VIRULENCE GENES IN PATHOGENIC BACTERIA 457 DIPHTHERIA 459 CHOLERA 460
WHOOPING COUGH 463 THE HEAT SHOCK REGULON 464 HEAT SHOCK RESPONSE IN
COLI 46 5 GENETIC ANALYSIS OF THE COLI HEAT SHOCK REGULON 465
REGULATION OF O 32 SYNTHESIS 465 REGULATION OF RIBOSOME AND TRNA
SYNTHESIS 467 RIBOSOMAL PROTEINS 468 RRNA AND TRNA REGULATION 470
MICROARRAY AND PROTEOMIC ANALYSIS OF REGULATORY NETWORKS 474 FROM GENES
TO REGULONS TO NETWORKS TO GENETIC ANALYSIS 474 SUMMARY 475 QUESTIONS
FOR THOUGHT 476 PROBLEMS 476 . SUGGESTED READING 477 PART IV GENES IN
PRACTICE 479 CHAPTER MOLECULAR GENETIC ANALYSIS IN BACTERIA 481 THE LAD
GENE OF ESCHERICHIA COLI 482 ISOLATING DELETIONS INTO LAD GENE 482
ISOLATION OF LAD MISSENSE MUTATIONS 483 MAPPING OF THE LAD MISSENSE
MUTATIONS 483 ISOLATION OF TANDEM DUPLICATIONS OF THE HIS OPERON IN
SALMONELLA ENTERICA SEROVAR TYPHIMURIUM 484 A RECK MUTATION HELPS
STABILIZE THE DUPLICATIONS 486 DETERMINATION OF THE LENGTH OF TANDEM
DUPLICATIONS 486 FREQUENCY OF SPONTANEOUS DUPLICATIONS 487 ANALYSIS OF
PROTEIN TRANSPORT IN E. COLI 48 7 USE OF THE MAT GENES TO STUDY PROTEIN
TRANSPORT: SIGNAL SEQUENCES; SEC; AND SRP 487 GENETIC ANALYSIS OF
TRANSMEMBRANE DOMAINS OF INNER MEMBRANE PROTEINS 490 IDENTIFICATION OF
GENES FOR TRANSPORTED PROTEINS BY RANDOM PHOA FUSIONS 491 REPLICATION
CONTROL OF COLEL -DERIVED PLASMIDS 491 MUTATIONS THAT PREVENT
INTERACTION OF RNA I AND RNA II 493 MUTATIONS THAT CHANGE THE INC GROUP
493 IDENTIFICATION AND MAPPING OF THE TRA GENES ON A PLASMID 494
ISOLATION OF TRA MUTANT PLASMIDS 494 COMPLEMENTATION TESTS TO DETERMINE
THE NUMBER OF TRA GENES 495 GENETIC ANALYSIS OF SPORULATION IN BACILLUS
SUBTILIS 496 IDENTIFICATION OF GENES THAT REGULATE SPORULATION 498
REGULATION OF INITIATION OF SPORULATION 498 COMPARTMENTALIZED REGULATION
OF SPORULATION GENES 500 ANALYSIS OF THE ROLE OF SIGMA FACTORS IN
SPORULATION REGULATION 501 INTERCOMPARTMENTAL REGULATION DURING
DEVELOPMENT 503 FINDING SPORULATION GENES: MUTANT HUNTS, SUPPRESSOR
ANALYSIS, AND FUNCTIONAL GENOMICS 508 PROBLEMS 509 SUGGESTED READING 509
ANSWERS TO QUESTIONS FOR THOUGHT AND PROBLEMS 511 GLOSSARY 523 INDEX 549
|
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| author | Snyder, Larry Champness, Wendy |
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| ctrlnum | (OCoLC)49385863 (DE-599)BVBBV014438465 |
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| dewey-ones | 572 - Biochemistry |
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| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV014438465 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:02:45Z |
| institution | BVB |
| isbn | 155581204X |
| language | English |
| lccn | 2002018697 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009869226 |
| oclc_num | 49385863 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-20 DE-M49 DE-BY-TUM DE-11 |
| owner_facet | DE-355 DE-BY-UBR DE-20 DE-M49 DE-BY-TUM DE-11 |
| physical | XVI, 566 S. Ill., graph. Darst. |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | ASM Press |
| record_format | marc |
| spelling | Snyder, Larry Verfasser aut Molecular genetics of bacteria Larry Snyder and Wendy Champness 2. ed. Washington, D.C. ASM Press 2003 XVI, 566 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Bactériophages - Génétique Genética bacteriana larpcal Genética molecular larpcal Génétique bactérienne Génétique moléculaire Bacteria genetics Bacterial genetics Bacteriophages Genetics Bacteriophages genetics Chromosomes, Bacterial Genetics, Microbial methods Molecular Biology methods Molecular genetics Bakteriophagen (DE-588)4125508-2 gnd rswk-swf Bakterien (DE-588)4004296-0 gnd rswk-swf Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Gentechnologie (DE-588)4071722-7 gnd rswk-swf Bakteriophagen (DE-588)4125508-2 s Molekulargenetik (DE-588)4039987-4 s DE-604 Bakterien (DE-588)4004296-0 s Gentechnologie (DE-588)4071722-7 s Champness, Wendy Verfasser aut HEBIS Datenaustausch Mainz application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009869226&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Snyder, Larry Champness, Wendy Molecular genetics of bacteria Bactériophages - Génétique Genética bacteriana larpcal Genética molecular larpcal Génétique bactérienne Génétique moléculaire Bacteria genetics Bacterial genetics Bacteriophages Genetics Bacteriophages genetics Chromosomes, Bacterial Genetics, Microbial methods Molecular Biology methods Molecular genetics Bakteriophagen (DE-588)4125508-2 gnd Bakterien (DE-588)4004296-0 gnd Molekulargenetik (DE-588)4039987-4 gnd Gentechnologie (DE-588)4071722-7 gnd |
| subject_GND | (DE-588)4125508-2 (DE-588)4004296-0 (DE-588)4039987-4 (DE-588)4071722-7 |
| title | Molecular genetics of bacteria |
| title_auth | Molecular genetics of bacteria |
| title_exact_search | Molecular genetics of bacteria |
| title_full | Molecular genetics of bacteria Larry Snyder and Wendy Champness |
| title_fullStr | Molecular genetics of bacteria Larry Snyder and Wendy Champness |
| title_full_unstemmed | Molecular genetics of bacteria Larry Snyder and Wendy Champness |
| title_short | Molecular genetics of bacteria |
| title_sort | molecular genetics of bacteria |
| topic | Bactériophages - Génétique Genética bacteriana larpcal Genética molecular larpcal Génétique bactérienne Génétique moléculaire Bacteria genetics Bacterial genetics Bacteriophages Genetics Bacteriophages genetics Chromosomes, Bacterial Genetics, Microbial methods Molecular Biology methods Molecular genetics Bakteriophagen (DE-588)4125508-2 gnd Bakterien (DE-588)4004296-0 gnd Molekulargenetik (DE-588)4039987-4 gnd Gentechnologie (DE-588)4071722-7 gnd |
| topic_facet | Bactériophages - Génétique Genética bacteriana Genética molecular Génétique bactérienne Génétique moléculaire Bacteria genetics Bacterial genetics Bacteriophages Genetics Bacteriophages genetics Chromosomes, Bacterial Genetics, Microbial methods Molecular Biology methods Molecular genetics Bakteriophagen Bakterien Molekulargenetik Gentechnologie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009869226&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT snyderlarry moleculargeneticsofbacteria AT champnesswendy moleculargeneticsofbacteria |