Mechanisms of drug resistance in epilepsy: lessons from oncology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Chichester
Wiley
2002
|
| Schriftenreihe: | Novartis Foundation Symposium
243 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VIII, 246 S. Ill., graph. Darst. |
| ISBN: | 047084146X |
Internformat
MARC
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| 650 | 4 | |a Cellules cancéreuses - Résistance aux médicaments - Congrès | |
| 650 | 4 | |a Résistance aux médicaments - Congrès | |
| 650 | 4 | |a Épilepsie - Chimiothérapie - Congrès | |
| 650 | 4 | |a Drug Resistance |v Congresses | |
| 650 | 4 | |a Drug resistance in cancer cells |v Congresses | |
| 650 | 4 | |a Drug resistance |v Congresses | |
| 650 | 4 | |a Epilepsy |x Chemotherapy |v Congresses | |
| 650 | 4 | |a Epilepsy |x drug therapy |v Congresses | |
| 650 | 4 | |a P-Glycoproteins |x metabolism |v Congresses | |
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Datensatz im Suchindex
| _version_ | 1804129180988735488 |
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| adam_text | Contents
Symposium on Mechanisms of drug resistance in epilepsy: lessons from oncology, held at the Xorartis
Foundation, London, 13 15 March 2001
Hditors: Gregory Hock (Organiser) and Jamie Goode
This symposium is based on a proposal made by Simon Shorvon andSanjay Sisodiya
Victor Ling Chair s introduction 1
J.W.Sander The problem of the drug resistant epilepsies 4
Discussion 12
George L. Scheffer and Rik J. Scheper Drug resistance molecules: lessons from
oncology 19
Discussion 31
N. Joan Abbott, Ehsan U. Khan, Christopher M. S. Rollinson, Andreas Reichel,
Damir Janigro, Stephen M. Dombrowski, Michael S. Dobbie and
David J. Begley Drug resistance in epilepsy: the role of the blood brain
barrier 38
Discussion 47
Andras Varadi, Gergely Szakacs, Eva Bakos and Balazs Sarkadi P glycoprotein
and the mechanism of multidrug resistance 54
Discussion 65
Jan Wijnholds Drug resistance caused by multidrug resistance associated
proteins 69
Discussion 80
Susan E. Bates, Clara Chen, Robert Robey, Min Kang,William D. Figg anil
Tito Fojo Reversal of multidrug resistance: lessons trom clinical oncology 83
Discuss inn 96
Amit M. Oza Clinical development of Pglycoprotein modulators in oncology 103
Discussion 115
v
vi CONTENTS
Peter Atadja,YanYan Neale, Harry Tbwbin, Frank Buxton and Dalia Cohen
Gene expression profiling of epothilone A resistant cells 119
Discussion 132
N. H. Hendrikse and W. Vaalburg Imaging of P glycoprotein function in vivo with
PET 137
Discussion 145
Wolfgang Loscher Animal models of drug resistant epilepsy 149
Discussion 159
S. M. Sisodiya,W. R. Lin, B. N. Harding, M.V. Squier and M. Thorn
Drug resistance in epilepsy: human epilepsy 167
Discussion 174
General discussion I 180
R. A. Deisz Cellular mechanisms of pharmacoresistance in slices from epilepsy
surgery 186
Discussion 199
Ulrich Brinkmann Functional polymorphisms of the human multidrug resistance
(MDRf) gene: correlation with P glycoprotein expression and activity in vivo 207
Discussion 210
Michael J. Newman, Ross Dixon and BarryToyonaga OC144 093, a novel P
glycoprotein inhibitor for the enhancement of anti epileptic therapy 213
Discussion 226
Final general discussion 231
Victor Ling Closing remarks 236
Index of contributors 237
Subject index 239
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| id | DE-604.BV014288209 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:01:03Z |
| institution | BVB |
| isbn | 047084146X |
| language | English |
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| physical | VIII, 246 S. Ill., graph. Darst. |
| publishDate | 2002 |
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| publisher | Wiley |
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| spelling | Mechanisms of drug resistance in epilepsy lessons from oncology Chichester Wiley 2002 VIII, 246 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Novartis Foundation Symposium 243 Cellules cancéreuses - Résistance aux médicaments - Congrès Résistance aux médicaments - Congrès Épilepsie - Chimiothérapie - Congrès Drug Resistance Congresses Drug resistance in cancer cells Congresses Drug resistance Congresses Epilepsy Chemotherapy Congresses Epilepsy drug therapy Congresses P-Glycoproteins metabolism Congresses Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Antiepileptikum (DE-588)4142656-3 gnd rswk-swf Therapieresistenz (DE-588)4133317-2 gnd rswk-swf Epilepsie (DE-588)4015035-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2001 London gnd-content Epilepsie (DE-588)4015035-5 s Pharmakotherapie (DE-588)4076066-2 s Therapieresistenz (DE-588)4133317-2 s DE-604 Antiepileptikum (DE-588)4142656-3 s Novartis Foundation Symposium 243 (DE-604)BV011990857 243 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009799605&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mechanisms of drug resistance in epilepsy lessons from oncology Novartis Foundation Symposium Cellules cancéreuses - Résistance aux médicaments - Congrès Résistance aux médicaments - Congrès Épilepsie - Chimiothérapie - Congrès Drug Resistance Congresses Drug resistance in cancer cells Congresses Drug resistance Congresses Epilepsy Chemotherapy Congresses Epilepsy drug therapy Congresses P-Glycoproteins metabolism Congresses Pharmakotherapie (DE-588)4076066-2 gnd Antiepileptikum (DE-588)4142656-3 gnd Therapieresistenz (DE-588)4133317-2 gnd Epilepsie (DE-588)4015035-5 gnd |
| subject_GND | (DE-588)4076066-2 (DE-588)4142656-3 (DE-588)4133317-2 (DE-588)4015035-5 (DE-588)1071861417 |
| title | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_auth | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_exact_search | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_full | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_fullStr | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_full_unstemmed | Mechanisms of drug resistance in epilepsy lessons from oncology |
| title_short | Mechanisms of drug resistance in epilepsy |
| title_sort | mechanisms of drug resistance in epilepsy lessons from oncology |
| title_sub | lessons from oncology |
| topic | Cellules cancéreuses - Résistance aux médicaments - Congrès Résistance aux médicaments - Congrès Épilepsie - Chimiothérapie - Congrès Drug Resistance Congresses Drug resistance in cancer cells Congresses Drug resistance Congresses Epilepsy Chemotherapy Congresses Epilepsy drug therapy Congresses P-Glycoproteins metabolism Congresses Pharmakotherapie (DE-588)4076066-2 gnd Antiepileptikum (DE-588)4142656-3 gnd Therapieresistenz (DE-588)4133317-2 gnd Epilepsie (DE-588)4015035-5 gnd |
| topic_facet | Cellules cancéreuses - Résistance aux médicaments - Congrès Résistance aux médicaments - Congrès Épilepsie - Chimiothérapie - Congrès Drug Resistance Congresses Drug resistance in cancer cells Congresses Drug resistance Congresses Epilepsy Chemotherapy Congresses Epilepsy drug therapy Congresses P-Glycoproteins metabolism Congresses Pharmakotherapie Antiepileptikum Therapieresistenz Epilepsie Konferenzschrift 2001 London |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009799605&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV011990857 |