Advances in prostaglandin and leukotriene research: basic science and new clinical applications
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Dordrecht [u.a.]
Kluwer Acad. Publ.
2001
|
| Schriftenreihe: | Medical science symposia series
16 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXI, 203 S. Ill., graph. Darst. |
| ISBN: | 1402001460 |
Internformat
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| 245 | 1 | 0 | |a Advances in prostaglandin and leukotriene research |b basic science and new clinical applications |c ed. by B. Samuelsson ... |
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Datensatz im Suchindex
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| adam_text | Contents
Preface ix
List of Contributors xi
I LIPOXYGENASES AND LEUKOTRIENE BIOSYNTHESIS
1. Phosphorylation and Activation of 5 Lipoxygenase by P38 Kinase Activated MAPKAP Kinases
O. Werz, J. Klemm, O. Radmark, and B. Samuelsson 1
2. 5 Lipoxygenase and the Nucleus: Where, When, How, and Why?
M.Peters Golden, and T.G. Brock 9
3. Calcium Binding Site of 5 Lipoxygenase
T. Hammarberg, P. Provost, K. V. Reddy, B. Persson, and O Radmark 17
4. Regulation of Cellular 5 Lipoxygenase Activity by Glutathione Peroxidases
D. Schumann, 0 Werz, D. Szellas, and D. Steinhilber 21
5. Novel Aspects Related to Biosynthesis and Biological Actions of Hepoxilins: Interrelationship with
Phosphohpid Hydro Peroxide Glutathione Peroxidase (PHGPx)
P. Shankaranarayanan, M. Sutherland, H. Waiczies, T. Schewe, and S. Nigam 25
6. Transcriptional Regulation of the Human Leukotriene C4 Synthase Promoter
J. L. Zhao, K.F. Austen, and B.K. Lam 31
7. Localization and Translocation of Enzymes Involved in Leukotriene Biosynthesis
Y. Ide, H. Hanaka, T. Hirabayashi, T. Shimizu, and T. Izumi 37
II Cyclooxygenases and Prostaglandin Biosynthesis
8. Regulation of COX 2 Expression in Fibroblasts, Osteoblasts, Mast Cells, and Macrophages
H.R. Herschman, D.J. Wadleigh, and ST. Reddy 41
9. Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase 2: A Novel Mechanism for
NSAID and N 3 PUFA Therapeutic Actions
C.N. Serhan, CB. Clish, J. Brannon, S.P. Colgan, K. Gronert, and N. Chiang 49
10. Substrate Interactions in the Cyclooxygenase 1 Active Site
ED. Thuresson, M.G. Malkowski, KM. Lakkides. C.J Rieke, Y. Sun, B. Wingerd, RJ. Micielli, R.M.
Garavito, and W.L. Smith 57
vi
11. Mutation of the Human Prostacyclin Synthase Gene
T. Nakayama, M. Sotna, D. Rehemudula, and K. Kanmatsuse 65
12. Structure and Function of Two Distinct Types of Prostaglandin D Synthase
Y. Urade, and O. Hayaishi 69
13. Roles of Prostaglandin F Synthase
A:. Watanabe, T. Suzuki Yamamoto, M.Nishizawa, M. Fukui, K. Ishimura, andS. Ito 73
14. Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells
S. I. Murota, M. Onodera, and I. Morita 11
III Phospholipase A2
15. On the Functional Diversity of Secreted Phospholipases A2: Cloning of Novel Mammalian and HIV
1 Antiviral Properties
G. Lambeau, E. Valentin, R. Koduri, D. Fenard, A. Doglio, M. Gelb, andM. Lazdunski 81
16. Regulation of Cytosolic Phospholipase A2 by Phosphorylation
M.H. Gelb, Y. Hefner, A.G. Borsch Haubold, andS.P. Watson 85
IV Cytochrome P450 Archidonate Metabolites
17. Synthesis and Function of 20 Hydroxyeicosatetraenoic Acid in the Kidney
M. Laniado Schwartzman, J. Marji, M. Jiang., andM. H. Wang 89
V Receptors
18. Altered Bronchodilation and Pulmonary Inflammation in Prostanoid EP2 Receptor Knockout Mice
F. Nantel, D. Denis, S. Wong, P. Masson, D. Normandin, M. Cirino, G. P. O Neill, R.M. Breyer, and
KM. Metiers 99
19. Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell
K. Yamamoto, J. Wang, Y. Sugimoto, A. Ichikawa, and S. Yamamoto 103
20. BLT2, a Second Leukotriene B4 Receptor
T. Yokomizo, K. Kato, K. Terawaki, T. humi, and T. Shimizu 107
21. Upregulation of Cysteinyl Leukotriene 1 Receptor Expression by lnterleukin 5 in Human
Leukocytes
M. Rola Pleszczynski, M. Thivierge, andj. Stankova 111
22. Physiological and Pathophysiological Roles of Prostanoids; Lessons from Receptor Knockout Mice
for Clinical Applications
S. Narumiya 115
23. Multiple G Protein Coupling of Chimeric Prostacyclin/Prostaglandin D2 Receptors
H. Wise, andK.B.S. Chow 121
vii
VI ElCOSANOIDS AND NEUROSCIENCE
24. An Unusual Nicotinic Acetylcholine Receptor Activates the 8 Lipoxygenase Pathway in Aplysia
Neurons
S.J. Feinmark, T.L. Tieman, J. Kehoe, andJ.H. Schwartz 125
VII Cardiovascular System
25. Neutrophil Endothelial Cell Interaction: A Multidirectional Cross Talk in Leukotriene Generation
G.C. Folco 129
26. Cyclooxygenase in the Lamb Ductus Arteriosus: Developmental Changes and Upregulation
F. Coceani, C. Ackerley, E. Seidtitz, andL. Kelsey 135
27. Co Localization of Prostacyclin (PGI2) Synthase and Caveolin 1 in Endothelial Cells Underscores
New Roles of PGI2 In Angiogenesis
E. Spisni, C. Griffoni, S. Santi, M. Riccio, R. Marulli, and V. Tomasi 139
VIII Respiratory System
28. Leukotriene C4 Synthase Gene Polymorphism in Severe Asthma
A. Sampson, I. Sayers, P. Howarth, and S. Holgate 143
IX Inflammation
29. Anti Inflammatory Levels of Aspirin and Salicylate Inhibit Integrin Dependent Human Neutrophil
Aggregation and PMN Influx in COX2 and NFkB(P105) Knockout Mice
G. Weissmann, M.C. Montesinos, M. Pillinger, andB.N. Cronstein 149
30. Antipyretic Action of Acetaminophen: Inhibition of the Cyclooxygenase Activity of Endothelial
Cells Treated with IL 1
J.A. Oates, L.J. Marnett, and O. Boutaud 155
31. Leukotriene Mediated Alteration of Endothelial Barrier Function
N. Gautam, L. Lindbom, and P. Hedqvist I59
32. GI and Cardiovascular Profiles of New NSAIDs: Selective COX 2 Inhibitors and NO NSAIDs
M.N. Muscara, W. McKnight, M. Dicay, and J.I. Wallace 163
33. NO Releasing NSAIDs Modulate Cytokine Secretion
S. Fiorucci and E. Antonelli 171
34. Potent Inhibitory Effects of a NO NSAID (Flurbiprofen Nitroxybutylester) on Bone Resorption in
Vitro and in Vivo
S.H. Ralston. K.J. Armour, R.J. Van t Hof, K.E. Armour, and P. Del Soldato 179
viii
X Cancer
35. Lipid Peroxidation and Cyclooxygenase 2 Activity in Human Hepatocellular Carcinoma Cell Lines
with and without Multiple Drug Resistance: Correlation with Cell Growth
E. Masini, O. Fantappie, I. Sardi, L. Raimondi, V. Fabbroni, P.F. Mannaioni, and R. Mazzanti 183
36. Pulmonary Prostacyclin Synthase Overexpression Improves Survival Following Butylated
Hydroxytoluene Exposure
R.L. Keith, Y.E. Miller, T.L. Gesell, M.D. Moore, A.M. Malkinson, andM.W. Geraci 187
XI ISOPROSTANES
37. Reactive Products of the Isoprostane Pathway: Isoketals and Cyclopentenone A2/J2 Isoprostanes
L.J. Roberts II, Y. Chen, O. Boutaud, S.S. Davies, J.D. MorrowJ.A. Oates and C. Brame 191
38. Increased Isoprostane 8 epi PGF2A in Statin Induced Myopathy
H. Sinzinger, G. Lupattelli, and F. Chehne 197
Index 201
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| spelling | Advances in prostaglandin and leukotriene research basic science and new clinical applications ed. by B. Samuelsson ... Dordrecht [u.a.] Kluwer Acad. Publ. 2001 XXI, 203 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Medical science symposia series 16 Leukotrienes Congresses Prostaglandins Congresses Prostaglandine (DE-588)4127390-4 gnd rswk-swf Leukotriene (DE-588)4198723-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2000 Florenz gnd-content Prostaglandine (DE-588)4127390-4 s DE-604 Leukotriene (DE-588)4198723-8 s Samuelsson, Bengt Sonstige oth Medical science symposia series 16 (DE-604)BV008340509 16 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009756897&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Advances in prostaglandin and leukotriene research basic science and new clinical applications Medical science symposia series Leukotrienes Congresses Prostaglandins Congresses Prostaglandine (DE-588)4127390-4 gnd Leukotriene (DE-588)4198723-8 gnd |
| subject_GND | (DE-588)4127390-4 (DE-588)4198723-8 (DE-588)1071861417 |
| title | Advances in prostaglandin and leukotriene research basic science and new clinical applications |
| title_auth | Advances in prostaglandin and leukotriene research basic science and new clinical applications |
| title_exact_search | Advances in prostaglandin and leukotriene research basic science and new clinical applications |
| title_full | Advances in prostaglandin and leukotriene research basic science and new clinical applications ed. by B. Samuelsson ... |
| title_fullStr | Advances in prostaglandin and leukotriene research basic science and new clinical applications ed. by B. Samuelsson ... |
| title_full_unstemmed | Advances in prostaglandin and leukotriene research basic science and new clinical applications ed. by B. Samuelsson ... |
| title_short | Advances in prostaglandin and leukotriene research |
| title_sort | advances in prostaglandin and leukotriene research basic science and new clinical applications |
| title_sub | basic science and new clinical applications |
| topic | Leukotrienes Congresses Prostaglandins Congresses Prostaglandine (DE-588)4127390-4 gnd Leukotriene (DE-588)4198723-8 gnd |
| topic_facet | Leukotrienes Congresses Prostaglandins Congresses Prostaglandine Leukotriene Konferenzschrift 2000 Florenz |
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