Biomarkers in risk assessment: validity and validation
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Geneva
World Health Organization
2001
|
| Schriftenreihe: | Environmental health criteria
222 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 238 S. graph. Darst. |
| ISBN: | 9241572221 |
Internformat
MARC
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS W
BIOMARKERS IN RISK ASSESSMENT: VALlbff¥ AND VALIDATION
PREAMBLE vi
ABBREVIATIONS xiv
1. INTRODUCTION 1
2. RISK ASSESSMENT 7
2.1 Hazard identification 9
2.2 Dose response 13
2.3 Exposure assessment for risk assessment 14
3. VALIDITY AND VALIDATION GENERAL
CONSIDERATIONS 16
4. VALIDATION OF SPECIFIC TYPES OF
BIOMARKERS 21
4.1 Exposure biomarkers 21
4.2 Effect biomarkers 22
4.3 Susceptibility biomarkers 26
5. CROSS SPECIES COMPARABILITY 30
6. NEW PERSPECTIVES 33
7. SUMMARY 35
8. CONCLUSIONS 36
9. RECOMMENDATIONS 37
9.1 General recommendations 37
9.2 Recommendations for future research 37
EHC 222: Biomarkers in Risk Assessment: Validity Validation
9.2.1 Prevalidation stage 37
9.2.2 Validation stage 38
9.3 Application 38
REFERENCES 39
APPENDIX I. BIOMARKERS OF EXPOSURE AND
EFFECT FOR CARCINOGENICITY 47
APPENDIX II. BIOMARKERS OF EXPOSURE AND
EFFECT FOR NON CARCINOGENIC END POINTS 95
APPENDIX III. MEASUREMENT OF DRUG
METABOLIZING ENZYME POLYMORPHISMS AS
INDICATORS OF SUSCEPTIBILITY 146
APPENDIX IV. VALIDATION OF BIOMARKERS FOR
ENVIRONMENTAL HEALTH RESEARCH
AND RISK ASSESSMENT 202
RESUME 235
RESUMEN 237
|
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV014162953 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:58:48Z |
| institution | BVB |
| isbn | 9241572221 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009707346 |
| oclc_num | 587667426 |
| open_access_boolean | |
| owner | DE-12 DE-Er8 |
| owner_facet | DE-12 DE-Er8 |
| physical | XIV, 238 S. graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | World Health Organization |
| record_format | marc |
| series | Environmental health criteria |
| series2 | Environmental health criteria |
| spelling | Biomarkers in risk assessment validity and validation Geneva World Health Organization 2001 XIV, 238 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Environmental health criteria 222 Biomarker (DE-588)4425928-1 gnd rswk-swf Umweltchemikalie (DE-588)4117281-4 gnd rswk-swf Risikoanalyse (DE-588)4137042-9 gnd rswk-swf Toxizitätstest (DE-588)4060540-1 gnd rswk-swf Gesundheitsgefährdung (DE-588)4071808-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Umweltchemikalie (DE-588)4117281-4 s Toxizitätstest (DE-588)4060540-1 s Biomarker (DE-588)4425928-1 s DE-604 Gesundheitsgefährdung (DE-588)4071808-6 s Risikoanalyse (DE-588)4137042-9 s Environmental health criteria 222 (DE-604)BV000011459 222 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009707346&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Biomarkers in risk assessment validity and validation Environmental health criteria Biomarker (DE-588)4425928-1 gnd Umweltchemikalie (DE-588)4117281-4 gnd Risikoanalyse (DE-588)4137042-9 gnd Toxizitätstest (DE-588)4060540-1 gnd Gesundheitsgefährdung (DE-588)4071808-6 gnd |
| subject_GND | (DE-588)4425928-1 (DE-588)4117281-4 (DE-588)4137042-9 (DE-588)4060540-1 (DE-588)4071808-6 (DE-588)4143413-4 |
| title | Biomarkers in risk assessment validity and validation |
| title_auth | Biomarkers in risk assessment validity and validation |
| title_exact_search | Biomarkers in risk assessment validity and validation |
| title_full | Biomarkers in risk assessment validity and validation |
| title_fullStr | Biomarkers in risk assessment validity and validation |
| title_full_unstemmed | Biomarkers in risk assessment validity and validation |
| title_short | Biomarkers in risk assessment |
| title_sort | biomarkers in risk assessment validity and validation |
| title_sub | validity and validation |
| topic | Biomarker (DE-588)4425928-1 gnd Umweltchemikalie (DE-588)4117281-4 gnd Risikoanalyse (DE-588)4137042-9 gnd Toxizitätstest (DE-588)4060540-1 gnd Gesundheitsgefährdung (DE-588)4071808-6 gnd |
| topic_facet | Biomarker Umweltchemikalie Risikoanalyse Toxizitätstest Gesundheitsgefährdung Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009707346&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000011459 |