IgE and Anti-IgE therapy in asthma and allergic disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Dekker
2002
|
| Schriftenreihe: | Lung biology in health and disease
164 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXV, 542 S. graph. Darst. |
| ISBN: | 0824706633 |
Internformat
MARC
| LEADER | 00000nam a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV014150436 | ||
| 003 | DE-604 | ||
| 005 | 20020612 | ||
| 007 | t | ||
| 008 | 020214s2002 d||| |||| 00||| eng d | ||
| 020 | |a 0824706633 |9 0-8247-0663-3 | ||
| 035 | |a (OCoLC)48958620 | ||
| 035 | |a (DE-599)BVBBV014150436 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-12 | ||
| 050 | 0 | |a RC591 | |
| 082 | 0 | |a 616.2/3806 |2 21 | |
| 084 | |a XD 3415 |0 (DE-625)152555:12921 |2 rvk | ||
| 245 | 1 | 0 | |a IgE and Anti-IgE therapy in asthma and allergic disease |c ed. by Robert B. Fick ... |
| 264 | 1 | |a New York [u.a.] |b Dekker |c 2002 | |
| 300 | |a XXV, 542 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Lung biology in health and disease |v 164 | |
| 650 | 7 | |a Asthme |2 ram | |
| 650 | 7 | |a Autoanticorps antiimmunoglobuline E |2 ram | |
| 650 | 2 | |a Hypersensibilité | |
| 650 | 2 | |a Immunoglobuline E - immunologie | |
| 650 | 2 | |a Immunoglobuline E - usage thérapeutique | |
| 650 | 7 | |a Immunoglobulines |2 ram | |
| 650 | 4 | |a Anti-immunoglobulin E autoantibodies | |
| 650 | 4 | |a Asthma | |
| 650 | 4 | |a Asthma |x therapy | |
| 650 | 4 | |a Hypersensitivity |x therapy | |
| 650 | 4 | |a Immunoglobulin E | |
| 650 | 4 | |a Immunoglobulin E |x immunology | |
| 650 | 4 | |a Immunoglobulin E |x therapeutic use | |
| 650 | 0 | 7 | |a Allergie |0 (DE-588)4001257-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Allergisches Asthma |0 (DE-588)4275602-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Immunglobulintherapie |0 (DE-588)4161377-6 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Allergie |0 (DE-588)4001257-8 |D s |
| 689 | 0 | 1 | |a Immunglobulintherapie |0 (DE-588)4161377-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Allergisches Asthma |0 (DE-588)4275602-9 |D s |
| 689 | 1 | 1 | |a Immunglobulintherapie |0 (DE-588)4161377-6 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Fick, Robert B. |e Sonstige |4 oth | |
| 830 | 0 | |a Lung biology in health and disease |v 164 |w (DE-604)BV000008326 |9 164 | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009698078&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-009698078 | ||
Datensatz im Suchindex
| _version_ | 1804129024697434112 |
|---|---|
| adam_text | CONTENTS
Introduction Claude Lenfant Hi
Foreword Kimishige Ishizaka v
Preface ix
Contributors xiii
1. Introduction 1
S. G. O. Johansson
References 4
2. Serum IgE Distributions in Normal and Asthmatic Subjects 7
Chantal Matkin Dolan, James D. Reimann, Sharon Safrin, and
Robert B. Fick, Jr.
I. Introduction 7
II. IgE Levels in Normal, Healthy Subjects 8
III. IgE Levels in Asthmatic and Allergic Populations 11
IV. New Data from Clinical Trials 15
V. Conclusion 17
References 18
xix
1 X
xx Contents
3. Understanding the Binding of IgE to Its High Affinity
Receptor and to an Anti IgE Antibody 23
Leonard G. Presta and Robert L. Shields
I. Defining IgE Epitopes That Interact with FceRI 24
II. Nonanaphylactogenic Anti IgE Antibody Identification
and Humanization 26
III. Possible Mechanisms of Action of Anti IgE E25
Antibody 32
IV. Summary 32
References 33
4. Mediator Release from Basophils and Mast Cells and Its
Relationship to FceRI Expression and IgE Suppressing
Therapies 39
Donald W. MacGlashan, Jr., John T. Schroeder, Lawrence M.
Lichtenstein, Sarbjit S. Saini, and Bruce S. Bochner
I. Introduction 39
II. Secretory Functions of Basophils and Mast Cells 40
III. FceRI Expression on Basophils and Mast Cells 47
IV. In Vivo Regulation of FceRI on Human Basophils 54
V. Conclusion 60
References 61
5. Expression of IgE Receptors on Eosinophils 69
David Dombrowicz, Andre Capron, and Monique Capron
I. Introduction 69
II. General Structure of FceRI and FceRII 70
III. Presence of IgE Receptors on Eosinophils 72
IV. Functions in the Immune Response 76
V. Potential Pitfalls of Anti IgE Therapy in Patients with
Parasitic Infections 78
References 79
6. Eosinophil IgE Receptors: Controversy and Consensus 87
Hirohito Kita and Cheryl R. Adolphson
I. Introduction 87
II. History of IgE Receptors on Eosinophils 88
III. Low Affinity IgE Receptor (FceRII/CD23) on Human
Eosinophils 90
IV. High Affinity IgE Receptor (FceRI) on Human
Eosinophils 92
Contents Xxi
V. Cautions, Potential Problems, and Future Directions 94
References 97
7. Murine Models of Asthma: Caveats and Conclusions on the
Contribution of IgE and Mast Cells to Allergic Inflammation,
Airway Hyperresponsiveness, and Airflow Obstruction 103
Jeffrey S. Tepper and Daniel B. Tumas
I. Evidence Indicating a Lack of Involvement of Mast
Cells in Murine Asthma Models 105
II. Evidence Indicating a Lack of Involvement of IgE in
Murine Asthma Models 106
III. Study 1: Role of IgE and Mast Cells in a Systemic
OVA Sensitization Model 108
IV. Evidence for the Involvement of Mast Cells and IgE in
Murine Asthma Models 112
V. Study 2: The Role of IgE in Murine Asthma
Determined by the Model 114
VI. Summary and Conclusions 118
References 120
8. Role of IgE in Asthma: Pathogenesis and Novel Therapeutic
Strategies 125
James Laurence Lordan, Stephen T. Holgate, and Ian Sayers
I. Introduction 125
II. Asthma Epidemiology: The Significance of Allergen j
Specific IgE 126 j
III. Pathological Features of Asthma 126 !
IV. Cellular Involvement in Asthma 129 |
V. Mechanisms of Asthma Severity and Chronicity 133 j
VI. IgE Facilitated Antigen Presentation in Asthma 134 •
VII. Role of Costimulatory Molecules 135 |
VIII. The Bronchial Epithelium as a Regulator of Airway j
Inflammation 136 j
IX. Cytokine Networks in Asthma 137 I
X. Transcription Factors 142
XI. Evidence of Airway Remodeling in Asthma 143
XII. Intrinsic and Extrinsic Asthma: A Role for Local
Airway IgE Production in Both? 145
XIII. IgE Synthesis in the Asthmatic Airway 146
XIV. The Role of FceRI and CD23 in Allergic Disorders 153
XV. Early and Late Asthmatic Responses: Role of IgE 159
xxii Contents
XVI. Molecular Therapeutic Strategies for Asthma 163
XVII. Conclusion 168
References 168
9. IgE Mediated Response to Allergen in the
Bronchoprovocation Laboratory 191
Louis Philippe Boulet and Donald W. Cockcroft
I. Introduction 191
II. History 191
III. Airway Response to Allergen 192
IV. Standardization of Allergen Provocation Tests 196
V. Allergen Provocation to Study Physiopathology of
Asthma and Mechanisms of Action of Asthma Drugs 202
VI. Predicting the Clinical Efficacy of Asthma Drugs from
Their Inhibitory Effect on Allergen Bronchoprovocation 207
VII. Allergen Provocation and the Development of New
Therapeutic Agents 209
VIII. Conclusion 210
References 211
10. Pathophysiology of the Airway Response to Inhaled Allergen
in Asthmatic Subjects: Role of IgE 219
John V. Fahy
I. Introduction 219
II. Mechanism of the Early Asthmatic Response 220
III. Mechanism of the Late Asthmatic Response 223
IV. Summary and Conclusions 228
References 228
11. Efficacy and Safety of Xolair Anti IgE Monoclonal Antibody
in Adult Asthmatics 235
Robert B. Fick, Jr., and W. James Metzger
I. Introduction 235
II. U.S. and International Studies of Xolair Administered
Subcutaneously to Moderate Severe Asthmatics 237
III. Study of Xolair Anti IgE in Severe Asthma 244
IV. Conclusions 250
References 250
1
Contents xxiii
12. The Role of IgE in Pediatric Asthma 253
Henry Milgrom and Charles Johnson
I. Introduction 253
II. Etiology and Epidemiology of Pediatric Asthma 255
III. Role of IgE in the Pathogenesis of Asthma 258
IV. Therapy with Anti IgE 259
References 261
13. Anti inflammatory Activities of Omalizumab (Xolair),
a Recombinant Humanized Monoclonal Antibody
Binding IgE 265
Robert B. Fick, Jr.
I. Anti inflammatory Effects of Omalizumab in Preclinical
Studies 266
II. Anti inflammatory Effects of Omalizumab in Studies of
Human Physiology and Clinical Trials 268
III. Anti inflammatory Effects in the Upper Airway 277
IV. Conclusion 278
References 279
14. Pulmonary Delivery of Anti IgE: Rationale for Topical
Delivery to the Airway 283
Theresa D. Sweeney, Melinda Marian, Jane Ruppel, and
Jeanine L. Bussiere
I. Introduction 283
II. Permeability of Lung Epithelium to E25 285
III. Dose Estimation and Safety of Aerosolized E25 290
IV. Human Clinical Studies 294
V. Summary and Conclusions 296
References 296
15. Treatment of Seasonal Allergic Rhinitis 299
Thomas B. Casale and Patricia W. Rohane
I. Introduction 299
II. Pathophysiology 300
III. Diagnosis 305
IV. Management 307
V. Overall Conclusions 319
References 319
xxiv Contents
16. Anti IgE and Allergic Skin Diseases 327
Michael F. Hofer and Donald Y. M. Leung
I. Introduction 327
II. Atopic Dermatitis 327
III. Urticaria and Angioedema 336
IV. Other Autoimmune Diseases with Skin Involvement 341
V. Conclusions 342
References 342
17. Role of IgE and Food Allergens 351
Ricki M. Helm and A. Wesley Burks
I. Introduction 351
II. Characterization of Food Allergens 353
III. Pathophysiology of IgE Mediated Food Allergy 354
IV. Major Foods/Allergens Involved with IgE Mediated
Disease 356
V. Diagnosis of Food Allergy 363
VI. Cross Sensitivity Between Foods 367
VII. Prevention 368
VIII. Control 370
IX. Treatment 371
X. Genetically Engineered Crop Plants 373
XI. Epidemiology/Case Studies 375
XII. Summary 376
References 377
18. Role of IgE in Allergic Bronchopulmonary Aspergillosis 385
Priscilla S. A. Sarinas and Rajinder K. Chitkara
I. Introduction 385
II. Protean Manifestations of Aspergillosis 386
III. Allergic Bronchopulmonary Aspergillosis 386
IV. IgE and Immunopathogenesis 387
V. Pathology 391
VI. Diagnosis 392
VII. Clinical Stages 398
VIII. Treatment 400
IX. Conclusions 401
References 401
Contents xxv
19. IgE and Its Role in Parasitic Helminth Infection:
Implications for Anti IgE Based Therapies 409
Philip J. Cooper and Thomas B. Nutman
I. Introduction 409
II. Natural History of the Immune Response to Human
Helminth Infections 410
III. Role of IgE in Human Helminth Infections 411
IV. Does IgE Have a Protective Role Against Helminth
Infections? 415
V. Animal Models of Impact of Anti IgE on Helminth
Infections 416
VI. Potential Risks in Travelers to Endemic Areas 417
VII. Potential Risks in Individuals with Undiagnosed
Helminth Infections 417
VIII. Conclusions 418
References 418
20. The Rise of Antibodies as Therapeutics 427
Maureen P. Quan and Paul Carter
I. Introduction 427
II. Antibody Structure and Function 427
III. Problems That Have Beset Antibody Therapeutics 434
IV. Core Antibody Technologies 438
V. Formats for Antibody Therapeutics 444
VI. Production of Antibody Drugs 448
VII. Technologies for Enhancing Antibody Therapeutics 451
VIII. Trends with Antibody Therapeutics 456
Author Index 471
Subject Index 531
. A
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV014150436 |
| callnumber-first | R - Medicine |
| callnumber-label | RC591 |
| callnumber-raw | RC591 |
| callnumber-search | RC591 |
| callnumber-sort | RC 3591 |
| callnumber-subject | RC - Internal Medicine |
| classification_rvk | XD 3415 |
| ctrlnum | (OCoLC)48958620 (DE-599)BVBBV014150436 |
| dewey-full | 616.2/3806 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.2/3806 |
| dewey-search | 616.2/3806 |
| dewey-sort | 3616.2 43806 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02241nam a2200589 cb4500</leader><controlfield tag="001">BV014150436</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20020612 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">020214s2002 d||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0824706633</subfield><subfield code="9">0-8247-0663-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)48958620</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV014150436</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-12</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC591</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.2/3806</subfield><subfield code="2">21</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XD 3415</subfield><subfield code="0">(DE-625)152555:12921</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">IgE and Anti-IgE therapy in asthma and allergic disease</subfield><subfield code="c">ed. by Robert B. Fick ...</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York [u.a.]</subfield><subfield code="b">Dekker</subfield><subfield code="c">2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XXV, 542 S.</subfield><subfield code="b">graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Lung biology in health and disease</subfield><subfield code="v">164</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Asthme</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Autoanticorps antiimmunoglobuline E</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Hypersensibilité</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Immunoglobuline E - immunologie</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Immunoglobuline E - usage thérapeutique</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Immunoglobulines</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-immunoglobulin E autoantibodies</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Asthma</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Asthma</subfield><subfield code="x">therapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypersensitivity</subfield><subfield code="x">therapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunoglobulin E</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunoglobulin E</subfield><subfield code="x">immunology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunoglobulin E</subfield><subfield code="x">therapeutic use</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Allergie</subfield><subfield code="0">(DE-588)4001257-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Allergisches Asthma</subfield><subfield code="0">(DE-588)4275602-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Immunglobulintherapie</subfield><subfield code="0">(DE-588)4161377-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Allergie</subfield><subfield code="0">(DE-588)4001257-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Immunglobulintherapie</subfield><subfield code="0">(DE-588)4161377-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Allergisches Asthma</subfield><subfield code="0">(DE-588)4275602-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Immunglobulintherapie</subfield><subfield code="0">(DE-588)4161377-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fick, Robert B.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Lung biology in health and disease</subfield><subfield code="v">164</subfield><subfield code="w">(DE-604)BV000008326</subfield><subfield code="9">164</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009698078&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-009698078</subfield></datafield></record></collection> |
| id | DE-604.BV014150436 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:58:34Z |
| institution | BVB |
| isbn | 0824706633 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009698078 |
| oclc_num | 48958620 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-12 |
| owner_facet | DE-355 DE-BY-UBR DE-12 |
| physical | XXV, 542 S. graph. Darst. |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | Dekker |
| record_format | marc |
| series | Lung biology in health and disease |
| series2 | Lung biology in health and disease |
| spelling | IgE and Anti-IgE therapy in asthma and allergic disease ed. by Robert B. Fick ... New York [u.a.] Dekker 2002 XXV, 542 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Lung biology in health and disease 164 Asthme ram Autoanticorps antiimmunoglobuline E ram Hypersensibilité Immunoglobuline E - immunologie Immunoglobuline E - usage thérapeutique Immunoglobulines ram Anti-immunoglobulin E autoantibodies Asthma Asthma therapy Hypersensitivity therapy Immunoglobulin E Immunoglobulin E immunology Immunoglobulin E therapeutic use Allergie (DE-588)4001257-8 gnd rswk-swf Allergisches Asthma (DE-588)4275602-9 gnd rswk-swf Immunglobulintherapie (DE-588)4161377-6 gnd rswk-swf Allergie (DE-588)4001257-8 s Immunglobulintherapie (DE-588)4161377-6 s DE-604 Allergisches Asthma (DE-588)4275602-9 s Fick, Robert B. Sonstige oth Lung biology in health and disease 164 (DE-604)BV000008326 164 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009698078&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | IgE and Anti-IgE therapy in asthma and allergic disease Lung biology in health and disease Asthme ram Autoanticorps antiimmunoglobuline E ram Hypersensibilité Immunoglobuline E - immunologie Immunoglobuline E - usage thérapeutique Immunoglobulines ram Anti-immunoglobulin E autoantibodies Asthma Asthma therapy Hypersensitivity therapy Immunoglobulin E Immunoglobulin E immunology Immunoglobulin E therapeutic use Allergie (DE-588)4001257-8 gnd Allergisches Asthma (DE-588)4275602-9 gnd Immunglobulintherapie (DE-588)4161377-6 gnd |
| subject_GND | (DE-588)4001257-8 (DE-588)4275602-9 (DE-588)4161377-6 |
| title | IgE and Anti-IgE therapy in asthma and allergic disease |
| title_auth | IgE and Anti-IgE therapy in asthma and allergic disease |
| title_exact_search | IgE and Anti-IgE therapy in asthma and allergic disease |
| title_full | IgE and Anti-IgE therapy in asthma and allergic disease ed. by Robert B. Fick ... |
| title_fullStr | IgE and Anti-IgE therapy in asthma and allergic disease ed. by Robert B. Fick ... |
| title_full_unstemmed | IgE and Anti-IgE therapy in asthma and allergic disease ed. by Robert B. Fick ... |
| title_short | IgE and Anti-IgE therapy in asthma and allergic disease |
| title_sort | ige and anti ige therapy in asthma and allergic disease |
| topic | Asthme ram Autoanticorps antiimmunoglobuline E ram Hypersensibilité Immunoglobuline E - immunologie Immunoglobuline E - usage thérapeutique Immunoglobulines ram Anti-immunoglobulin E autoantibodies Asthma Asthma therapy Hypersensitivity therapy Immunoglobulin E Immunoglobulin E immunology Immunoglobulin E therapeutic use Allergie (DE-588)4001257-8 gnd Allergisches Asthma (DE-588)4275602-9 gnd Immunglobulintherapie (DE-588)4161377-6 gnd |
| topic_facet | Asthme Autoanticorps antiimmunoglobuline E Hypersensibilité Immunoglobuline E - immunologie Immunoglobuline E - usage thérapeutique Immunoglobulines Anti-immunoglobulin E autoantibodies Asthma Asthma therapy Hypersensitivity therapy Immunoglobulin E Immunoglobulin E immunology Immunoglobulin E therapeutic use Allergie Allergisches Asthma Immunglobulintherapie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009698078&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000008326 |
| work_keys_str_mv | AT fickrobertb igeandantiigetherapyinasthmaandallergicdisease |