New vistas in therapeutics: from drug design to gene therapy
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2001
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
953 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 253 S. Ill., graph. Darst. |
| ISBN: | 1573313351 157331336X |
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 953
December 2001
NEW VISTAS IN THERAPEUTICS
FROM DRUG DESIGN TO GENE THERAPY
Editors
Sonia I. Skarlatos, Paul Velletri, and Mariana Morris
Conference Organizers
Mariana Morris, C. Frank Bennet, Paul A. Velletri, Amy Trainor,
Sonia Skarlatos, and Victor J. Dzau
DRUG RESISTANT TUBERCULOSIS
FROM MOLECULES TO MACRO ECONOMICS
Editor
Peter Davies
Advisory Board
Peter Davies, Marty Adair, Francis Drebniewski, Jane Leese,
John Moore Gillon, Peter Ormerod, John Porter, Anton Pozniak,
and Jack Tinker
[This volume is the result of two conferences: New Vistas in Therapeutics: From Drug
Design to Gene Therapy, sponsored by the American Society for Biochemistry and
Molecular Biology (ASBMB) and the American Society for Pharmacology and Experi¬
mental Therapeutics (ASPET) and held as a FASEB satellite meeting on June 3 4,2000 in
Boston, Massachusetts; and Tuberculosis Drug Resistance: From Molecules to
Macro Economics, sponsored by Royal Society of Medicine, Liverpool Medical Institu¬
tion, and TB Focus and held on March 29 30, 2001 in London.]
contents
New Vistas in Therapeutics: From Drug Design to Gene Therapy
Introduction. By Sonia I. Skarlatos and Victor Dzau 1
Medicinals for the Millennia: The Historical Record. By GORDON M. CRAGG
and David J. Newman 3
Gene Therapy: A Brief Overview of the Past, Present, and Future. By ROLAND
Scollay 26
Gene Therapy for Cardiovascular Disorders: Is There a Future? By Beverly L.
Metcalfe, Kathleen W. Sellers, Michael Jing Ren Jeng, Matthew
J. HUENTELMAN, MICHAEL J. KATOVICH, AND MOHAN K. RAIZADA 31
Retroviral Approaches to Gene Therapy of Cystic Fibrosis. By LARRY G.
Johnson 43
Regulated Gene Expression in Gene Therapy. By Philip W. Zoltick and
James M. Wilson 53
AAV Mediated Gene Transfer for Hemophilia. By Katherine A. HIGH 64
Bone Marrow as a Source of Endothelial Cells for Natural and Iatrogenic
Vascular Repair. By Jeffrey M. Isner, Christoph Kalka, Atsuhiko
Kawamoto, and Takayuki Asahara 75
Drug Resistant Tuberculosis: From Molecules
to Macro economics
Introduction. By Peter Da vies 87
Part I. The Scale of the Problem
The Burden of Drug Resistant Tuberculosis and Mechanisms for Its Control.
By Mario C. Raviglione, Rajesh Gupta, Christopher M. Dye, and
Marcos A. Espinal 88
India s Multidrug Resistant Tuberculosis Crisis. By ZARIR F. Udwadia 98
Drug Resistant Tuberculosis in Africa. By A. Mwinga 106
Problems in Prisons Worldwide, with a Particular Focus on Russia. By
Vivien Stern 113
The Impact of Worldwide Drug Resistance on the United Kingdom. By JOHN
Watson 120
Specific Features of the Spread of Tuberculosis in Russia at the End of the 20th
Century. By MARGARITA V. Shilova 124
Tuberculosis in Russia and the Problem of Multiple Drug Resistance. By
V.V. Yerokhin, V.V. Punga, and L.N. Rybka 133
Part II. Scientific Basis of Drug Resistant Tuberculosis
Molecular Techniques in the Diagnosis of Mycobacterium tuberculosis and
the Detection of Drug Resistance. By M. Caws and
F.A. Drobniewski 138
Letting the Genome Out of the Bottle: Prospects for New Drug Development.
By Douglas Young 146
The Genetics of Host Resistance and Susceptibility to Tuberculosis. By Peter
Da vies and John Grange 151
Pharmacological Issues in the Treatment of Tuberculosis. By Charles A.
Peloquin 157
Part III. Clinical Aspects of Drug Resistance
DOTS and DOTS Plus: Not the Only Answer. By Paul Farmer 165
Part IV. Practicalities of Prevention
The Clinical Management of the Drug Resistant Patient. By Peter Ormerod 185
Multidrug Resistant Tuberculosis and HIV Infection. By Anton Pozniak ... 192
Holding the Patient. By GlNi Williams 199
Part V. Coercion or Commitment: Policies of Prevention
Moral Problems in the Use of Coercion in Dealing with Nonadherence in the
Diagnosis and Treatment of Tuberculosis. By Len Doyal 208
Just Coercion? Detention of Nonadherent Tuberculosis Patients. By RICHARD
Coker 216
Missed Opportunities? Coercion or Commitment: Policies of Prevention. By
John D.H. Porter and Jessica A. Ogden 224
Part VI. The Future
Multidrug Resistant Tuberculosis: This Is the Cost. By John Moore Gillon 233
Drug Resistant Tuberculosis: Concluding Remarks. By Peter D.O. Davies .. 241
Index of Contributors 247
Subjectlndex 249
Financial assistance for New Vistas in Therapeutics: From Drug Design to
Gene Therapy was received from:
• DUPONT PHARMACEUTICALS COMPANY
• ISIS PHARMACEUTICALS
• ASTRAZENECA
• VERTEX PHARMACEUTICALS INCORPORATED
Financial assistance for Drug Resistant Tuberculosis: From Molecules to
Macro Economics was received from:
• DEPARTMENT FOR INTERNATIONAL DEVELOPMENT,
UNITED KINGDOM
• DEPARTMENT OF HEALTH, UNITED KINGDOM
• ROCHE
• MERCK SHARP DOHME
• SWEDISH ORPHAN
• BOEHRINGER ENGELHEIM
• ORGANON
• 3M
• INTERMUNE PHARMACEUTICALS, INC.
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| spelling | New vistas in therapeutics from drug design to gene therapy ed. by Sonia I. Skarlatos ... Drug resistant tuberculosis New York, NY New York Acad. of Sciences 2001 253 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 953 Antituberkulotikum (DE-588)4194234-6 gnd rswk-swf Gentherapie (DE-588)4296957-8 gnd rswk-swf Arzneimittelresistenz (DE-588)4143180-7 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2000 Boston Mass. gnd-content Gentherapie (DE-588)4296957-8 s DE-604 Antituberkulotikum (DE-588)4194234-6 s Arzneimittelresistenz (DE-588)4143180-7 s Skarlatos, Sonia I. Sonstige oth Annals of the New York Academy of Sciences 953 (DE-604)BV002532608 953 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009694089&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Drug resistant tuberculosis ed. by Peter Davies |
| spellingShingle | New vistas in therapeutics from drug design to gene therapy Annals of the New York Academy of Sciences Antituberkulotikum (DE-588)4194234-6 gnd Gentherapie (DE-588)4296957-8 gnd Arzneimittelresistenz (DE-588)4143180-7 gnd |
| subject_GND | (DE-588)4194234-6 (DE-588)4296957-8 (DE-588)4143180-7 (DE-588)1071861417 |
| title | New vistas in therapeutics from drug design to gene therapy |
| title_alt | Drug resistant tuberculosis |
| title_auth | New vistas in therapeutics from drug design to gene therapy |
| title_exact_search | New vistas in therapeutics from drug design to gene therapy |
| title_full | New vistas in therapeutics from drug design to gene therapy ed. by Sonia I. Skarlatos ... |
| title_fullStr | New vistas in therapeutics from drug design to gene therapy ed. by Sonia I. Skarlatos ... |
| title_full_unstemmed | New vistas in therapeutics from drug design to gene therapy ed. by Sonia I. Skarlatos ... |
| title_short | New vistas in therapeutics |
| title_sort | new vistas in therapeutics from drug design to gene therapy |
| title_sub | from drug design to gene therapy |
| topic | Antituberkulotikum (DE-588)4194234-6 gnd Gentherapie (DE-588)4296957-8 gnd Arzneimittelresistenz (DE-588)4143180-7 gnd |
| topic_facet | Antituberkulotikum Gentherapie Arzneimittelresistenz Konferenzschrift 2000 Boston Mass. |
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