Optimal dose identification: proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000
Gespeichert in:
Format: | Buch |
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Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Excerpta Medica
2001
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Schriftenreihe: | International congress series
Esteve Foundation symposia ; 9 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XII, 278 S. Ill., graph. Darst. |
ISBN: | 0444506284 |
Internformat
MARC
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Datensatz im Suchindex
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adam_text | xi
Contents
About the Esteve Foundation v
Introduction vii
List of participants jx
CONFERENCE INFORMATION
The use of preclinical pharmacokinetic and pharmacodynamic data to
predict clinical doses: current and future perspectives
P. Morgan (UK) 1
Optimal dose identification: predicting a safe dose in man from animal
studies
B.K. Park, N.R. Kitteringham, J.L. Maggs, D. Boocock, I. White, R. Elsby,
M. Pirmohamed (UK) 13
Clinical pharmacology of morphine and morphine 6 glucuronide A
PK/PD modeling approach
J. Lotsch (Germany) 27
The use of cognitive tests to facilitate drug and dose selection in Phase I
and to optimise dosing in Phase IV
K.A. Wesnes (UK) 35
Dose optimization in drug development: role of phase IV trials
P.H. Joubert (Switzerland) 51
PK/PD approach to dose selection
LB. Sheiner (USA) 67
Mechanism based modelling of CNS drug effect: from receptor phar¬
macology to clinical trial
M. Danhof (The Netherlands) 79
Pharmacokinetic pharmacodynamic modeling in anesthesia
P.L. Gambus, IF. Troconiz (Spain) 89
Dose optimisation in pain control
H. McQuay (UK) 99
xii
The dose concentration effect relationships—the basis for TDM. A
critical appraisal
L.F. Gram (Denmark) 117
Medication non compliance. When hard science meets soft science
G. Levy (USA) 125
Concentration controlled therapy
N.H.G. Holford (New Zealand) 135
Therapeutic drug monitoring of anti HIV drugs
D.J. Back, S.H. Khoo, S.E. Gibbons, H, Reynolds, J.F. Tjia (UK),
C. Merry (USA) 145
The role of molecular biology in pharmacodynamic research
J. Oliver, D.J. Webb (UK) 161
Genetic and environmental causes for interindividual variability in drug
pharmacokinetics
M. Ingelman Sundberg (Sweden) 175
Genetic determinants of dose optimisation: molecular biology in the
prevention of drug toxicity
M. Pirmohamed, B.K. Park (UK) 187
Pharmacodynamics of cancer chemotherapy: childhood ALL as a model
W.E. Evans (USA) 203
Dose optimisation in antidepressant drug development
B. Deakin (UK) 223
Effect of liver disease on dose optimization
T.F. Blaschke (USA) 247
Dose optimisation—the effect of age
S.H.D. Jackson (UK) 259
Final remarks 273
Index of authors 275
Keyword index 277
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institution | BVB |
isbn | 0444506284 |
language | English |
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physical | XII, 278 S. Ill., graph. Darst. |
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spelling | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 ed.: Alasdair Breckenridge Amsterdam [u.a.] Excerpta Medica 2001 XII, 278 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier International congress series : Esteve Foundation symposia 9 Excerpta medica / International congress series 1220 Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Arzneimitteldosis (DE-588)4214417-6 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2000 Lloret Mar gnd-content Arzneimitteldosis (DE-588)4214417-6 s DE-604 Pharmakotherapie (DE-588)4076066-2 s Breckenridge, Alasdair Sonstige oth International congress series Excerpta medica 1220 (DE-604)BV000000592 1220 International congress series Esteve Foundation symposia ; 9 (DE-604)BV000625397 9 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009677167&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 International congress series Pharmakotherapie (DE-588)4076066-2 gnd Arzneimitteldosis (DE-588)4214417-6 gnd |
subject_GND | (DE-588)4076066-2 (DE-588)4214417-6 (DE-588)1071861417 |
title | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 |
title_auth | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 |
title_exact_search | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 |
title_full | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 ed.: Alasdair Breckenridge |
title_fullStr | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 ed.: Alasdair Breckenridge |
title_full_unstemmed | Optimal dose identification proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 ed.: Alasdair Breckenridge |
title_short | Optimal dose identification |
title_sort | optimal dose identification proceedings of the esteve foundation symposium ix lloret de mar girona spain 4 7 october 2000 |
title_sub | proceedings of the Esteve Foundation Symposium IX, Lloret de Mar (Girona), Spain, 4-7 October 2000 |
topic | Pharmakotherapie (DE-588)4076066-2 gnd Arzneimitteldosis (DE-588)4214417-6 gnd |
topic_facet | Pharmakotherapie Arzneimitteldosis Konferenzschrift 2000 Lloret Mar |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009677167&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV000000592 (DE-604)BV000625397 |
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