Medical dermatology:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Philadelphia [u.a.]
Saunders
2001
|
Schriftenreihe: | Dermatologic clinics
19,4 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | X S., S. 583 - 815 zahlr. Ill. |
Internformat
MARC
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245 | 1 | 0 | |a Medical dermatology |c Victoria P. Werth ... , guest eds. |
264 | 1 | |a Philadelphia [u.a.] |b Saunders |c 2001 | |
300 | |a X S., S. 583 - 815 |b zahlr. Ill. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
490 | 1 | |a Dermatologic clinics |v 19,4 | |
650 | 4 | |a Dermatology |x trends | |
650 | 4 | |a Skin Diseases | |
650 | 4 | |a Skin Manifestations | |
700 | 1 | |a Werth, Victoria P. |e Sonstige |4 oth | |
830 | 0 | |a Dermatologic clinics |v 19,4 |w (DE-604)BV000004924 |9 19,4 | |
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Datensatz im Suchindex
_version_ | 1804128957242540032 |
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adam_text | MEDICAL Dl RMATOJIX .Y
CONTENTS
Preface xi
Victoria P. Werth and Madeleine Duvic
Preserving Medical Dermatology: A Colleague Lost, A Call
to Arms, and a Plan for Battle 583
Victoria P. Werth, John Voorhees, Irwin M. Freedberg,
Richard D. Sontheimer
Medical dermatology is having a difficult time surviving, particularly in
academic centers. Without proper role models of academically thriving
medical dermatologists in these centers, it is hard to attract developing
dermatologists to this part of the field. This article provides an example
of the typical struggles encountered by academic medical dermatologists,
and suggests the causes of the various problems and their potential solu¬
tions.
Inpatient Dermatology: A Prescription for Survival 593
Srdjan Prodanovich, Robert S. Kirsner, and Francisco A. Kerdel
Although dermatologists continue to provide consultative services for
hospitalized patients, many academic dermatology centers across the
United States no longer provide primary hospital care. This radical change
will prevent many future generations of dermatologists from being trained
in the care of hospitalized patients, thus limiting their capacity to provide
comprehensive dermatologic care. This article focuses on the causes and
consequences of the current situation and suggests solutions.
Cutaneous Vasculitis Update 603
Lawrence E. Gibson
The classification of cutaneous vasculitis and its general principles, includ¬
ing clinical patterns, pathogenesis, and causes, are reviewed in this article.
Several types of cutaneous vasculitis are discussed in detail, including
Henoch Schonlein purpura, erythema elevatum diutinum, and cutaneous
polyarteritis nodosum. The approach to treatment for cutaneous vasculitis
also is reviewed.
PS8MATOLOCK:CUNICS !*^ ^ * *,•• •* , •. ,* :
Targeting Tumor Necrosis Factor Alpha: New Drugs Used to
Modulate Inflammatory Diseases 617
Jeffrey R. LaDuca and Anthony A. Gaspari
Tumor necrosis factor alpha (TNF a) is an inflammatory cytokine with a
role in several biologic systems, including immune modulation and host
defense against tumors and infections. The role of TNF a in inflammatory
diseases is increasingly understood. Its role in the pathophysiology of
Crohn s disease, rheumatoid arthritis, and many inflammatory skin disor¬
ders is well established. Three drugs that target TNF a recently have come
to market. Thalidomide enhances the degradation of mRNA encoding
TNF a, but also has immune modulating properties. This drug has a
notorious history, but is emerging as a therapeutic agent to treat inflam¬
matory, autoimmune, and neoplastic diseases. Etanercept and infliximab
are newer, more specific TNF a antagonists that are showing promise as
therapeutic agents. The authors describe these three drugs, their mecha¬
nisms, and indications. In addition, they speculate about the potential role
of these TNF a antagonists in treating various skin conditions.
New Imnumomodulating Drugs in Autoimmune
Blistering Diseases 637
Neil J. Korman
The autoimmune blistering diseases are a fascinating group of diseases
characterized by the presence of blisters involving the skin and mucous
membranes. Understanding of the diagnosis, pathophysiology, and ad¬
vances in treatment of these diseases has grown enormously in recent
years. In this article, the author discusses the major clinical and immuno
pathologic findings in bullous pemphigoid, mucous membrane pemphi
goid, epidermolysis bullosa acquisita, linea IgA bullous disease, and pem¬
phigus. The article focuses on the therapeutic management of patients
with autoimmune blistering diseases, including the appropriate treatment
of patients, with particular emphasis on the use of immunomodulating
and immunosuppresive agents.
Psoriasis: Immunopathology and Immunomodulation 649
Alice B. Gottleib
Biologies in development for the treatment of moderate to severe plaque
type psoriasis are discussed in this article. Immunomodulators used as
therapeutic, pathogenic probes will continue to identify targets that play
primary roles in the pathogenesis of psoriasis.
Leg Ulcer Diagnosis and Management 659
Michele M. Choucair and David P. Fivenson
Lower extremity ulcers can be challenging diagnostically and therapeuti
cally. This article provides an overview of the different kinds of lower
extremity wounds typically seen by the medical dermatologist. It also
reviews new treatment modalities, including topical growth factors and
bioengineered skin. A team approach is emphasized.
Mastocytosis 679
Michael D. Tharp and B. Jack Longley, Jr
Mastocytosis represents a heterogeneous group of clinical disorders re¬
sulting from the infiltration of mast cells in the skin and other organs.
Although mastocytosis was first described over 130 years ago, the patho
physiologic mechanisms responsible for this disease have been identified
only recently. This article discusses the salient clinical features of the
disease, the mechanisms responsible for its development, and provides
treatment approaches that have proven useful for managing patients with
this disorder.
New Advances in Severe Adverse Drug Reactions 697
Jean Revuz
Every new drug has the potential for causing cutaneous adverse drug
reactions. Usually the clinical pattern is well known and has been de¬
scribed in association with other drugs; new entities, however, are de¬
scribed frequently. This article reviews several of them.
Hair and Systemic Disease 711
Leonard C. Sperling
Hair loss (alopecia) occurs as a manifestation of numerous systemic dis¬
eases, but usually can be categorized into one of five general groups:
telogen effluvium, anagen arrest, follicular destruction, hair miniaturiza¬
tion, and hair shaft defects. An excess of hair also can be evidence of
internal disease, and there are two general categories of increased hair
density: hypertrichosis and hirsutism. The basic categories of hair disease
and the systemic conditions associated with them are discussed. The
history, physical examination, and histopathologic data usually are suffi¬
cient to categorize the form of hair disorder and may provide a clue to
the nature of the underlying systemic disease.
Management of High Risk Melanoma 727
Paola Bonaccorsi, John C. Ansel, and Cheryl A. Armstrong
Improved treatment options for patients with high risk melanoma are of
great importance to clinicians who participate in the care of these patients.
There remains an overall lack of response to existing treatment options,
which continues to fuel the efforts of basic scientists and clinicians to
pursue other approaches for the treatment of melanoma no longer limited
to the skin. Continued investigation into the innovative and concurrent use
of surgery, chemotherapy, immunotherapy, and radiation therapy holds
significant promise for improved outcomes in the management of patients
with this devastating disease.
Cutaneous T Cell Lymphoma: New Immunomodulators 737
Narin Apisarnthanarax and Madeleine Duvic
Out of the advances in molecular biology over the last two decades,
new classes of therapeutic agents have emerged, displaying immune and
biologic response modification activities in the treatment of cutaneous T
cell lymphoma. The three major classes of immunomodulators currently
include the interferons, retinoids, and interleukins. Although the precise
mode of action of these treatments in cutaneous T cell lymphoma is com¬
plex and largely unknown, evidence suggests that they perform their
activity on cellular growth and differentiation at the immunoregulatory
level. The immunomodulators that are available for cutaneous T cell lym¬
phoma treatment and those under investigation are discussed in this arti¬
cle.
mNTFNTS iv
Infectious Disease Update 749
Steven M. Manders
In recent years, many new infectious diseases have been newly described
or have re emerged after decades of relative obscurity. Many of these
entities have prominent mucocutaneous manifestations, making them of
great relevance to the dermatologist. The pathogenesis, recognition, and
therapy of several of these important diseases, including streptococcal and
staphylococcal disease, necrotizing fasciitis, ehrlichiosis, penicillosis, and
vibrio infection are discussed.
Advances in HIV Treatment and Treatment Toxicities 757
Daniel A. Carrasco and Stephen K. Tyring
This article discusses current and investigative antiretroviral therapy, in¬
cluding dosage, mechanism of action, required laboratory analysis, dietary
requirements, and treatment toxicities, with an emphasis on dermatologic
side effects.
Current Therapy
Surgical Practice Pearls 773
Michael L. Ramsey
Office based dermatologic surgery encompasses a broad range of proce¬
dures. Regardless of the specific techniques offered, surgical practice is
most rewarding when one constantly seeks to improve methods and
efficiency. This article discusses practical, inexpensive tips that the author
has learned from mentors, colleagues, nurses, and from his own practice.
These methods use courtesy, creativity, and common sense to improve
efficiency and satisfaction.
Postsurgical Wound Management 787
Christopher J. Arpey and Duane C. Whitaker
Achieving successful outcomes in dermatologic surgery depends on preop
erative planning, intraoperative diligence, and careful management of the
postsurgical phase of wound healing. The authors review the use of
dressings and analgesics and discuss commonly encountered complica¬
tions and features of early wound maturation that are important in manag¬
ing patients postoperatively.
Cumulative Index 2001 799
Subscription Information Inside back cover
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indexdate | 2024-07-09T18:57:29Z |
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language | English |
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physical | X S., S. 583 - 815 zahlr. Ill. |
publishDate | 2001 |
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publisher | Saunders |
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series | Dermatologic clinics |
series2 | Dermatologic clinics |
spelling | Medical dermatology Victoria P. Werth ... , guest eds. Philadelphia [u.a.] Saunders 2001 X S., S. 583 - 815 zahlr. Ill. txt rdacontent n rdamedia nc rdacarrier Dermatologic clinics 19,4 Dermatology trends Skin Diseases Skin Manifestations Werth, Victoria P. Sonstige oth Dermatologic clinics 19,4 (DE-604)BV000004924 19,4 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009653067&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Medical dermatology Dermatologic clinics Dermatology trends Skin Diseases Skin Manifestations |
title | Medical dermatology |
title_auth | Medical dermatology |
title_exact_search | Medical dermatology |
title_full | Medical dermatology Victoria P. Werth ... , guest eds. |
title_fullStr | Medical dermatology Victoria P. Werth ... , guest eds. |
title_full_unstemmed | Medical dermatology Victoria P. Werth ... , guest eds. |
title_short | Medical dermatology |
title_sort | medical dermatology |
topic | Dermatology trends Skin Diseases Skin Manifestations |
topic_facet | Dermatology trends Skin Diseases Skin Manifestations |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009653067&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV000004924 |
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