Endometriosis: emerging research and intervention strategies:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2002
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
955 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 408 S. Ill., graph. Darst. |
| ISBN: | 1573313815 1573313807 |
Internformat
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 955
March 2002
ENDOMETRIOSIS: EMERGING
RESEARCH AND INTERVENTION
STRATEGIES
Editors
KOJI YOSHINAGA AND ESTELLA C. PARROTT
Conference Organizers
ESTELLA C. PARROTT, KOJI YOSHINAGA, LINDA C. GlUDICE,
KEVIN G. OSTEEN, AND JERROLD HEINDEL
[This volume is the result of the NIH workshop entitled Endometriosis: Emerging
Research and Intervention Strategies held at NIH on April 9 10, 2001, in Bethesda,
Maryland, and sponsored by the National Institute of Child Health and Human Develop¬
ment, the National Institute of Environmental Health Sciences, and the Office of
Research on Women s Health.]
CONTENTS
Foreword. By Koji YOSHINAGA and ESTELLA C. ParroTT ix
Part I. Overviews: What Is Endometriosis?
Clinical Aspects of Endometriosis. By ANA A. MURPHY 1
The Epidemiology of Endometriosis. By DANIEL W. CRAMER AND
Stacey A. Missmer 11
Endometriosis and Infertility: A Cause Effect Relationship? By ROBERT L.
Barbieri and Stacey Missmer 23
Panel Discussion 34
Part II. Basic Biology of Endometriosis
Progesterone Mediated Endometrial Maturation Limits Matrix Metallo
proteinase (MMP) Expression in an Inflammatory like Environment:
A Regulatory System Altered in Endometriosis. By KEVIN G. OSTEEN,
Kaylon L. Bruner Tran, Nancy R. Keller, and Esther
Eisenberg 37
Mechanisms of Action of Estrogen and Progesterone. By FRANCESCO J.
DeMayo, Bihong Zhao, Norio Takamoto, and Sophia Y. Tsai ... 48
Premenstrual and Menstrual Changes in the Macaque and Human Endo
metrium: Relevance to Endometriosis. By Robert M. Brenner,
Nihar R. Nayak, Ov D. Slayden, Hilary O.D. Critchley, and
Rodney W. Kelly 60
Estrogen Production and Metabolism in Endometriosis. By SERDAR E.
Bulun, Sijun Yang, Zhojuan Fang, Bilgin Gurates,
mltsutoshi tamura, and slby sebastian 75
Panel Discussion 86
Part III. Growth Factors, Cytokines, and Angiogenic Factors
Angiogenic Factors in Endometriosis. By Robert N. Taylor, Dan I.
Lebovic, and Michael D. Mueller 89
Local Cytokines in Endometrial Tissue: The Role of Interleukin 8 in the
Pathogenesis of Endometriosis. By Aydin Arici 101
Control of Growth and Differentiation of the Endometrium: The Role of
Tissue Interactions. By Robert M. BlGSBY 110
Panel Discussion 118
Part IV. Matrix Modification in Endometrial Tissue
Circulating Ovarian Steroids and Endometrial Matrix Metalloproteinases
(MMPs). By Patrick Henriet, Patricia B. Cornet, Pascale
Lemoine, Christine Galant, Christian F. Singer, Pierre J.
Courtoy, Yves Eeckhout, and Etienne Marbaix 119
Paracrine Mediators of Endometrial Matrix Metalloproteinase Expression:
Potential Targets for Progestin Based Treatment of Endometriosis.
By Kevin G. Osteen, Kaylon L. Bruner Tran, David Ong,
and Esther Eisenberg 139
Paracrine Regulation of Matrix Metalloproteinase Expression in Endo¬
metriosis. By Kathy L. Sharpe Timms and Kathryn E. Cox 147
Panel Discussion 157
Part V. Immune System and Endometriosis
Regulation and Modulation of Abnormal Immune Responses in Endo¬
metriosis. By Neil Sidell, Shou Wei Han, and Sampath
Parthasarathy 159
Autoantibody Responses to Carbohydrate Epitopes in Endometriosis.
By Grant R. Yeaman, Jane E. Collins, and Gillian A. Lang 174
Macrophages, Oxidation, and Endometriosis. By Nalini Santanam,
Ana A. Murphy, and Sampath Parthasarathy 183
Panel Discussion 199
Part VI. Environment and Endometriosis
The Potential Role of Exposure to Environmental Toxicants in the Patho
physiology of Endometriosis. By SHERRY E. RlER 201
Environmental Contaminants and Dietary Factors in Endometriosis.
By Warren G. Foster and Sanjay K. Agarwal 213
Panel Discussion 230
Part VII. Genetics and Gene Expression in Endometriosis
The Genetic Epidemiology of Spontaneous Endometriosis in the Rhesus
Monkey. By Krina Zondervan, Lon Cardon, Ronald
Desrosiers, Dallas Hyde, Joseph Kemnitz, Keith Mansfield,
Jeff Roberts, Joan Scheffler, Daniel E. Weeks, and
Stephen Kennedy 233
Heritability and Molecular Genetic Studies of Endometriosis. By JOE LEIGH
Simpson and Farideh Z. Bischoff 239
The Molecular Basis for Implantation Failure in Endometriosis: On the Road
to Discovery. By Linda C. Giudice, Tracey L. Telles, Shalini
Lobo, and Lee Kao 252
Implantation Defects in Infertile Women with Endometriosis.
By Bruce A. Lessey 265
Role of Endometriosis in Cancer and Tumor Development. By LILLIAN
Marie Swiersz 281
Panel Discussion 293
Part VIII. In Vitro and Animal Models of Endometriosis
An In Vitro Model to Study the Pathogenesis of the Early Endometriosis
Lesion. By Craig A. Witz, Herve Dechaud, Iris A. Montoya
RODRIGUEZ, MlKA R. THOMAS, ANITHA S. NAIR, VICTORIA E.
Centonze, and Robert S. Schenken 296
A Modified Baboon Model for Endometriosis. By Asgerally T. Fazleabas,
Allison Brudney, Bilgin Gurates, Daniel Chai, and Serdar
Bulun 308
Using Rats as a Research Model for the Study of Endometriosis.
BvKathyL. Sharpe Timms 318
Experimental Endometriosis: The Nude Mouse as a Xenographic Host.
By Kaylon L. Bruner Tran, Deborah Webster Clair, and
Kevin G. Osteen 328
Panel Discussion 340
Part IX. Intervention Strategies
Conventional Medical Therapies for Endometriosis. By VALERIE
Montgomery Rice 343
Research Aspects of Endometriosis Surgery. By Dan C. Martin 353
The Treatment of Endometriosis: A Review of the Evidence. By DAVID L.
Olive and Elizabeth A. Pritts 360
Selective Progesterone Receptor Modulators (SPRMs): A Novel Therapeutic
Concept in Endometriosis. By Kristof Chwalisz, Ramesh Garg,
Robert M. Brenner, Gerd Schubert, and Walter Elger 373
Panel Discussion 389
Part X. Future Research Directions and Recommendations
Summary of Future Research Directions and Recommendations.
By KOJI YOSHINAGA AND ESTELLA C. PARROTT 394
Panel Discussion 396
Index of Contributors 407
Financial assistance was received from:
• NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN
DEVELOPMENT, NIH
• NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES, NIH
• OFFICE OF RESEARCH ON WOMEN S HEALTH, NIH
• PHARMACIA CORPORATION
• SERONO SYMPOSIA USA, INCORPORATED
• TAP PHARMACEUTICAL PRODUCTS, INCORPORATED
• WYETH AYERST RESEARCH
The New York Academy of Sciences believes it has a responsibility to provide an open
forum for discussion of scientific questions. The positions taken by the participants in
the reported conferences are their own and not necessarily those of the Academy. The
Academy has no intent to influence legislation by providing such forums.
I
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| spelling | Endometriosis: emerging research and intervention strategies ed. by Koji Yoshinaga ... New York, NY New York Acad. of Sciences 2002 IX, 408 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 955 Endometriose gtt Endométriose - Congrès Endometriosis Congresses Endometriosis therapy Congresses Research Congresses Endometriose (DE-588)4152177-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2001 Bethesda Md. gnd-content Endometriose (DE-588)4152177-8 s DE-604 Yoshinaga, Koji Sonstige oth Annals of the New York Academy of Sciences 955 (DE-604)BV002532608 955 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009626176&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Endometriosis: emerging research and intervention strategies |
| title_auth | Endometriosis: emerging research and intervention strategies |
| title_exact_search | Endometriosis: emerging research and intervention strategies |
| title_full | Endometriosis: emerging research and intervention strategies ed. by Koji Yoshinaga ... |
| title_fullStr | Endometriosis: emerging research and intervention strategies ed. by Koji Yoshinaga ... |
| title_full_unstemmed | Endometriosis: emerging research and intervention strategies ed. by Koji Yoshinaga ... |
| title_short | Endometriosis: emerging research and intervention strategies |
| title_sort | endometriosis emerging research and intervention strategies |
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| topic_facet | Endometriose Endométriose - Congrès Endometriosis Congresses Endometriosis therapy Congresses Research Congresses Konferenzschrift 2001 Bethesda Md. |
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