The liver: biology and pathobiology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Lippincott Williams & Wilkins
2001
|
| Ausgabe: | 4. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 1064 S. Ill., graph. Darst. |
| ISBN: | 0781723906 |
Internformat
MARC
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| 650 | 4 | |a Liver |x Pathophysiology | |
| 650 | 4 | |a Liver |x Physiology | |
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Datensatz im Suchindex
| _version_ | 1804128797127081984 |
|---|---|
| adam_text | contents
Contributing Authors xi
Preface xvii
Acknowledgments xix
H Indicates chapters from third edition
posted on website http://liver.med.tufts.edu
PART I: INTRODUCTION
1. Organizational Principles 3
ValeerJ. Desmet
2. Embryonic Development of the Liver 17
Kenneth S. Zaret
PART II: THE CELLS
W 1. Biology and Pathobiology ofActin in the Liver
M. James Phillips
W 2. Cytoskeleton: Intermediate Filaments
Samuel W. French
3. Gap and Tight Junctions in Liver:
Composition, Regulation, and Function 29
Takashi Kojima, Norimasa Sawada,
Heather S. Duffy, and David C. Spray
4. Motor Molecules 47
Peter Satir
W 3. Motor Molecules of the Cytoskeleton; Possible
Functions in the Hepatocyte
Peter Satir
5. Gene Regulation and In Vivo Function of Liver
Transcription Factors 59
Robert H. Costa, Ai Xuan Le Holterman,
Francisco M. Rausa, and Guy R. Adami
6. The Hepatocyte Plasma Membrane:
Organization, Differentiation, Biogenesis,
and Turnover 77
David Schachter
W 4. Plasma Membrane: Biogenesis and Turnover
Mamodi Yilla and Darrell Doyle
7. Hepatocyte Basolateral Membrane Organic
Anion Transporters 83
Allan W. Wolkoff and Frederick J. Suchy
8. The Hepatocyte Surface: Dynamic Polarity 97
Pamela L. Tuma and Ann L. Hubbard
W 5. Hepatocyte Surface Polarity
Ann L. Hubbard, ValarieA. Ban, and Laura J. Scott
9. The Endoplasmic Reticulum and Golgi Complex
in Secretory Membrane Transport 119
Jennifer Lippincott Schwartz
W 6. The Endoplasmic Reticulum Golgi Membrane
System
Jennifer Lippincott Schwartz
W 7. Mechanisms of Nuclear Entry
John A. Hanover
10. Molecular Mechanisms of Hepatocellular
Vesicle Formation 133
Sophie Dahan, Michel Dominguez,
and Mark A. McNiven
11. Receptor Mediated Endocytosis 161
Richard]. Stockert
12. Peroxisomal Assembly, Biology, and Disease
Relationship 179
Jennifer J. Smith and Richard A. Rachubinski
W 8. Peroxisomes
PaulB. Lazarow
W 9. Lysosomes
G. Gary Sahagian and Phyllis M. Novikqff
H W 10, Mitochondria
Peter C. Hinkle
Section A: Hepatocyte: Metabolism
W 11. Energy Metabolism
Sam Seifter and Sasha England
viii Contents
13. Integrated Cell Functions Apoptosis 187
Martina Miiller and Peter H. Krammer
14. Fundamentals of Cellular Osmoregulation 207
Kevin Strange
15. Roles of Intracellular Proteolysis in
Hepatocyte Cell Cycle, Aging, and
Programmed Cell Death 217
/. Fred Dice
16. Regulation of Hepatic Cholesterol
Homeostasis 231
Phillip B. Hylernon, William M. Pandak,
andZ. Reno Vlahcevic
W 12 . Lipoprotein Metabolism
Robert M. Glickman and Seymour M. Sabesin
17. Leptin and the Liver 249
Lee M. Kaplan
18. Hypoxic, Ischemic, and Reperfusion Injury
to Liver 257
JohnJ. Lemasters
19. Protective Mechanisms Against Reactive
Oxygen Species 281
Masayasu Inoue
W 13. Reactive Oxygen Species
Masayasu Inoue
H MA 74. Detoxication: Oxidation and Reduction
Daniel M. Ziegler
W 15. Detoxication: Conjugation and Hydrolysis
William B. Jakoby
20. Disorders of Bilirubin Metabolism 291
Namita Roy Chowdhury, Irwin M. Arias,
Allan W. Wolkoff, andjayanta Roy Chowdhury
W 16. Heme and Bile Pigment Metabolism
Jayanta Roy Chowdhury, Namita Roy Chowdhury,
Allan W. Wolkoff, and Irwin M. Arias
21. The Porphyrias 311
Peter N. Meissner, Richard J. Hift,
and Ralph E. Kirsch
W 17. Heme Biosynthesis, the Porphyrias, and the Liver
Elizabeth E. Wyckoffand James P, Kushner
22. Copper Metabolism and the Liver 331
Iqbal Hamza and Jonathan D. Gitlin
W 18. Copper and Zinc
Inmin Sternlieb
23. The Liver and Iron 345
Mark D. Fleming and Nancy C. Andrews
W 19. Liver and Iron
Stephen P. Young and Philip Aisen
W 20. Retinoid (Vitamin A) Metabolism and the Liver
William S. Blaner
H W 21. Liver in Relation to Water Soluble Vitamins
Donald B. McCormick andHamish N. Munro
Section B: Bile Secretion
24. The Biology of the Bile Canaliculus 361 !
Peter Ujhdzy, Helmut Kipp, Suniti Misra,
Yoshiyuki Wakabayashi, andlrwin M. Arias
W 22. Bile Acids
Alan E Hofmann
W 23, Enterohepatic Circulation
Martin C. Carey and William C. Duane
W 24. Bile Flow
Serge Erlinger
25. Conjugate Export Pumps of the Multidrug
Resistance Protein (MRP) Family in Liver 373
Dietrich Keppler, Jbrg Konig, and Anne T. Nies
26. Genetic Defects of Canalicular Transport 383
Richard J. Thompson and Sandra S. Strautnieks
27. Hormonal Regulation of Bile Secretion 389
Francis R, Simon
28. Nucleotide Transport and Regulation of Bile
Formation 411
Richard M. Roman and J. Gregory Fitz
29. The Pathobiology of Biliary Epithelia 421
Gianfranco Alpini, Richard T. Prall,
and Nicholas F. LaRusso
W 25. The Biology of Biliary Epithelia
Gianfranca Alpini, John 0. Phillips, and Nicholas E
LaRusso
Section C: Sinusoidal Cells
30. Endothelial and Pit Cells 437
Filip Braet, Dianzhong Luo, Ilan Spector, David
Vermijlen, and Eddie Wisse
31. Hepatic Stellate Cells: Morphology, Function,
and Regulation 455
Dan Li and Scott L. Friedman
W 26. Kupffer and Sinusoidal Endothelial Cells
Johan Kuiper, Adriaan Brouwer, Dick L. Knook, and
TheoJ. C. van Berkel
Section D: Extracellular Matrix
32. The Extracellular Matrix of the Liver 469
Patricia Greenwel andMarcos Rojkind
W 27. Extracellular Matrix
Marcos Rojkind and Patricia Greenwel
33. Integrins 475
Lucia R. Languino and Rebecca G. Wells
HErkki Ruoslahti, Michael D. Pierschbacher, and Wayne A.
Border
PART III: INTERRELATED CELL FUNCTIONS
34. Role of Inositol Trisphosphate and
Diacylglycerol in the Regulation of Liver
Function 485
John H. Exton
35. Synthesis of and Signaling Through D 3
Phosphoinositides 495
Rial A. Christensen, Isabel De Ads Scherpenseel, and
Lyuba Varticovski
36. Insulin and Other Growth Factors 511
M. Dodson Michael and Neil B. Ruderman
W 29, Insulin, Insulin Like Growth Factors and Their
Receptors
Neil Ruderman, Alan C, Moses, and David B. Moller
37. Cyclic AMP Signaling in the Liver:
Coupling Transcription to Physiology and
Proliferation 525
Giuseppe Servillo, Maria Agnese Delia Fazia,
and Paolo Sassone Corsi
38. Ca2+ Signaling in the Liver 537
Maria de Fatima Leite and Michael H. Nathanson
39. Nitric Oxide in the Liver 555
Mark G. Clemens
40. Interleukin 6 Signaling During the
Acute Phase Response of the Liver 565
Johannes G. Bode and Peter C. Heinrich
W 30. Leukotrienes and Other Eicosanoids in Liver
Pa thophysiology
Dietrich Keppler
Contents ix
41. Innate Immune Sensing and the
Toll Like Receptors 581
Bruce Beutler
42. Liver Regeneration 591
Nelson Fausto
W 31. Liver Regeneration
Nelson Fausto and Eric M. Webber
43. Hepatocyte Growth Factor: Its Role in Hepatic
Growth and Pathobiology 611
Reza Zarnegar, Marie C. DeFmnces,
and George K. Michaiopoulos
PART IV: THE ORGAN H W 32. Hepatic Microvascular System
Robert S. McCuskey
3 W 33. Flow, Cell Entry, Metabolic Disposal, and Product
Formation in the Liver
Carl A. Goresky, Andreas J. Schwab, and K. Sandy Pang
RA^TVrRiLATION TO~OTHER ORGANS
44. Hepatic Encephalopathy 633
Roger F. Butterworth
45. Alterations of the Kidney in Liver Disease 649
Paolo Gentilini, Giacomo Laffi, Massimo Pinzani,
and Giorgio La Villa
W 34. Kidney in Liver Disease
Murray Epstein
W 35. Interaction of Liver, Muscle, and Adipose Tissue in
the Regulation of Metabolism in Response to Nutritional
and Other Factors
Marc K Hellerstein andHamish N. Munro
W 36. Hypothalamic Pituitary LiverAxis: Growth
Hormone Controls Liver Sex
Jan Ake Gustafison
W 37. Vitamin K Dependent Blood Coagulation Proteins
Barbara C. Furie and Bruce Furie
3 W 38. Hemopoietic Functions of the Liver
Allan J. Erslev
W 39. Hepatobiliary Influences on the Skeletal System
JoelB, Mason andlrwin H. Rosenberg
3 W 40. Molecular Aspects of Autoimmune Liver Disease
Ian R. Mackay
X Contents
PART VI: PATHOBIOLOGIC ANALYSIS
46. Molecular Pathophysiology of Membrane
Transport Function in Cholestasis 663
James L. Boyer
47. The Biology of Portal Hypertension 679
Roberto J. Groszmann, Mauricio R Loureiro Silva,
and Ming Hung Tsai
48. al Antitrypsin Deficiency 699
David H. Perlmutter
49. Pathophysiology of Liver Fibrosis 721
Marcos Rojkind and Patricia Greenwel
50. Alcoholic and Nonalcoholic Steatohepatitis 739
Anna Mae Diehl
W 41. Ethanol and the Liver
Francis R. Weiner, Silvia Degli Esposti, and Mark A. Zern
51. Schistosomiasis: A Model of Immunologically
Mediated Liver Disease 755
Miguel J. Stadecker and Hector J. Hernandez
52. Immune Mechanisms of Viral Clearance
and Disease Pathogenesis During Viral
Hepatitis 763
Carlo Ferrari and Francis V. Chisari
53. Epidemiology, Natural History, and Prevention
of Viral Hepatitis 783
Miriam J. Alter and Beth P. Bell
54. Molecular Bases of Hepatitis B—
and Hepatitis C—Related Chronic Liver
Disease 801
Christian Brichot
55. Molecular Biology of Hepatitis
Viruses 831
Michael M. C. Lai and William S. Mason
56. Liver Transplantation: Factors Affecting the
Balance Between Tolerance and Rejection in
Experimental Models 857
Lina Lu, Shiguang Qian, and Angus W. Thomson
W 42. The Woodchuck Model of Hepatitis B Virus
infection
Bud C. Tennant and John L. Gerin
57. Viral Hepatitis: Antiviral Therapy 873
Joseph Torresi and Stephen Locarnini
PART VII: HORIZONS 58. Tissue Engineering of the Liver 901
Antonia E. Stephen, Robert Langer,
and Joseph P. Vacanti
59. A Genomic View of Hepatology:
The Example of Liver Fibrosis 909
Jose M. Lora, Deborah N. Farlow,
JSfadine Weich, and Jose Carlos Gutierrez Ramos
60. After Proteomics Comes Glycomics:
How Proteins and Saccharides Interact and
Influence Cell Biology 917
Ram Sasisekharan, Zachary Shriver,
Uma Narayanasami, and Ganesh Venkataraman
61. Liver Repopulation Through Cell j
Transplantation 927
David A. Shafritz, Mariana D. Dabeva, and
Markus Grompe
62. Liver Directed Gene Therapy 941
Clifford J. Steer, Betsy T. Kren, Namita Roy
Chotudhury, and Jayanta Roy Chowdhury
63. Novel Strategies for Manipulating Hepatic
Gene Expression In Vivo 963
Marxa I. Figueiredo and Eric R Sandgren
64. Regulation of the Eukaryotic Cell Cycle 977
David F. Crawford and Helen Piwnica Worms
65. Molecular and Cellular Control of
Angiogenesis 987
Patricia A. D Amore and Ira M. Herman
66. Dynamics of Hepatitis B Virus Infection 995
Martin A. Nowak
67. Telomeres and Telomerase in Experimental
Liver Cirrhosis 1001
Karl Lenhard Rudolph and Ronald A. DePinho
68. Mechanism(s) of Hepatocarcinogenesis: Insight
from Transgenic Mouse Models 1013
Snorri S. Thorgeirsson
69. Orphan Nuclear Receptors and Regulation of
Cholesterol and Bile Acid Metabolism 1029
Joyce J. Repa, Makoto Makishima, Timothy T. Lu,
and David J. Mangelsdorf
Subject Index 1041
|
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| dewey-full | 612.35 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.35 |
| dewey-search | 612.35 |
| dewey-sort | 3612.35 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| edition | 4. ed. |
| format | Book |
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| indexdate | 2024-07-09T18:54:57Z |
| institution | BVB |
| isbn | 0781723906 |
| language | English |
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| spelling | The liver biology and pathobiology ed.-in-chief: Irwin M. Arias ... 4. ed. Philadelphia [u.a.] Lippincott Williams & Wilkins 2001 XVI, 1064 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Fysiologie gtt Lever gtt Pathologische fysiologie gtt Liver Pathophysiology Liver Physiology Hepatologie (DE-588)4113885-5 gnd rswk-swf Leber (DE-588)4034933-0 gnd rswk-swf Leberkrankheit (DE-588)4034937-8 gnd rswk-swf Physiologie (DE-588)4045981-0 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Leberkrankheit (DE-588)4034937-8 s DE-604 Leber (DE-588)4034933-0 s Physiologie (DE-588)4045981-0 s Hepatologie (DE-588)4113885-5 s 2\p DE-604 Arias, Irwin M. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009546406&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The liver biology and pathobiology Fysiologie gtt Lever gtt Pathologische fysiologie gtt Liver Pathophysiology Liver Physiology Hepatologie (DE-588)4113885-5 gnd Leber (DE-588)4034933-0 gnd Leberkrankheit (DE-588)4034937-8 gnd Physiologie (DE-588)4045981-0 gnd |
| subject_GND | (DE-588)4113885-5 (DE-588)4034933-0 (DE-588)4034937-8 (DE-588)4045981-0 (DE-588)4143413-4 |
| title | The liver biology and pathobiology |
| title_auth | The liver biology and pathobiology |
| title_exact_search | The liver biology and pathobiology |
| title_full | The liver biology and pathobiology ed.-in-chief: Irwin M. Arias ... |
| title_fullStr | The liver biology and pathobiology ed.-in-chief: Irwin M. Arias ... |
| title_full_unstemmed | The liver biology and pathobiology ed.-in-chief: Irwin M. Arias ... |
| title_short | The liver |
| title_sort | the liver biology and pathobiology |
| title_sub | biology and pathobiology |
| topic | Fysiologie gtt Lever gtt Pathologische fysiologie gtt Liver Pathophysiology Liver Physiology Hepatologie (DE-588)4113885-5 gnd Leber (DE-588)4034933-0 gnd Leberkrankheit (DE-588)4034937-8 gnd Physiologie (DE-588)4045981-0 gnd |
| topic_facet | Fysiologie Lever Pathologische fysiologie Liver Pathophysiology Liver Physiology Hepatologie Leber Leberkrankheit Physiologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009546406&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT ariasirwinm theliverbiologyandpathobiology |