Trends in gastroenterology and hepatology: millenium 2000
Gespeichert in:
Format: | Buch |
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Sprache: | German |
Veröffentlicht: |
Tokyo [u.a.]
Springer
2001
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XVII, 370 S. Ill., graph. Darst. |
ISBN: | 4431703020 |
Internformat
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Contents
Preface V
Contributors XV
Part 1 Gastroenterology and the New Millennium
Reflecting Forward: Gastroenterology in the New Millennium
D.K. Podolsky 3
Part 2 Ulcerative Colitis Pathophysiology and Therapy
Pathophysiology of and New Treatment for Ulcerative Colitis
H. Asakura 15
Part 3 Life Style Related Diseases and Gastroenterology
New Target of Gastroenterology: Overcoming Life Style Related Diseases
S. Nakazawa 27
Part 4 Apoptosis in Digestive Organs
Examination of Cytotoxic T Lymphocyte Mediated Apoptosis Pathway in
Peptic Ulcer Formation with or without H. pylori Infection
T. Ohara, Y. Kanoh, T. Mashiko, S. Asaki, and S. Kudoh 35
Epidermal Growth Factor Inhibits Helicobacter pylori Lipopolysaccharide
Induced Apoptosis of Primary Cultures of Gastric Pit Cells
T. Kawahara, S. Teshima, K. Kishi, and K. Rokutan 43
Impaired Sensitivity to Fas Induced Apoptosis of Lymphocytes in
Ulcerative Colitis Lesions
H. Ueyama, T. Kiyohara, Y. Shinomura, and Y. Matsuzawa 47
\/n
VIII Contents
Tumor Necrosis Factor a Induced Hepatic Apoptosis and
Hepatocyte Sensitization
M. Nagaki, Y. Osawa, T. Naiki, and H. Moriwaki 53
Molecular Mechanisms of D Galactosamine/Lipopolysaccharide Induced
Fulminant Hepatic Failure in Mice and the Effects of Therapeutic Agents
S. Hirono, T. Nakama, and H. Tsubouchi 59
Ethanol Induced Apoptosis Mediated by Mitochondrial Permeability
Transition in Primary Cultured Sinusoidal Endothelial Cells
T. Kitamura, L.X. Li, M. Hirose, K. Iejima, N. Enomoto,
S. Matsuyama, Y. Takei, and N. Sato 63
Therapeutic Strategies for Hepatocellular Carcinoma Based on Analyses
for Resistance to Apoptosis Mediated by Activation of Intracellular
Signal Pathways
T. Ito, Y. Sasaki, H. Yoshihara, K. Suzuki, E. Masuda, Y. Yamada,
K. Arai, T. Kamada, N. Hayashi, and J.R. Wands 66
Expression of Apoptosis Related Factors in Human Pancreatic Duct
Cell Carcinoma and Intraductal Papillary Mucinous Tumor
K. Satoh, A. Masamune, K. Kaneko, M. Hirota, A. Satoh, and
T. Shimosegawa 71
Part 5 Is Nitric Oxide Friend or Foe?
Effect of Exogenous and Endogenous Nitric Oxide on Endothelial
Permeability Induced by Oxidants In Vitro
N. Okayama, M. Itoh, and J.S. Alexander 79
Gastric Carcinoma and Helicobacter pylori Infection: Role of Nitric
Oxide and Inflammatory Cytokines in Gastric Carcinogenesis
Y. Kitadai, K. Haruma, T. Goto, K. Komoto, S. Tanaka,
M. Yoshihara, K. Sumii, and K. Chayama 82
Does Cyclooxygenase 2 Down Regulate Gastric Inflammation?
S. Tsuji, W. H. Sun, M. Tsujii, S. Kawano, and M. Hori 86
Regulation of Mucin Synthesis by Neuronal Nitric Oxide Synthase
in Gastric Pit Cells
K. Rokutan, S. Teshima, T. Kawai, T. Kawahara, K. Kusumoto, and
K. Kishi 90
Role of Nitric Oxide and Capsaicin Sensitive Sensory Nerves in Gastric
Receptive Relaxation and Adaptive Relaxation in Isolated Stomachs of
Guinea Pigs
H. Uno and K. Higuchi 95
Contents IX
Role of Inducible Nitric Oxide Synthase in Murine Colitis
H. Ogawa, M. Yamamoto, H. Nakamura, and H. Ito 99
Role of Nitric Oxide in the Progression of Severe Acute Pancreatitis
A. Satoh, A. Masamune, and T. Shimosegawa 103
Role of Nitric Oxide in the Progression of Acute Pancreatitis
T. Nishino, S. Watanabe, H. Oyama, Y. Fukuya, N. Hayashi, and
M. Kobayashi 106
Protective Effect of Nitric Oxide on Acute Liver Failure in Rats
T. Kono, H. Kotani, T. Asama, N. Mamiya, N. Ando, N. Chisato,
K. Kamiya, M. Yoneda, J. Iwamoto, and S. Kasai 112
Regulatory Mechanism of Cationic Amino Acid Transporters in
Hepatic Sinusoidal Ito Cells
T. Saibara, K. Ookawauchi, N. Akisawa, S. Iwasaki, T. Maeda, and
S. Onishi 115
Part 6 Transcription Factors in Digestive Organs
Novel NADPH Oxidase, Moxl, Expressed in Cultured Gastric Pit Cells:
Modulation of NF kB Activation
S. Teshima, T. Kawahara, K. Kishi, and K. Rokutan 123
Role of PPARy in the Growth and Differentiation of Gastric and
Colorectal Cancers
Y. Miyazaki, S. Kitamura, Y. Shinomura, and Y. Matsuzawa 128
PPARy Ligand and Induction of Growth Arrest in Pancreatic Cancer Cells
A. Elnemr, T. Ohta, S. Fushida, I. Ninomiya, G. Nishimura,
H. Kitagawa, M. Kayahara, T. Terada, and K. Miwa 132
Role of (3 Catenin During Early Colorectal and Hepatic Carcinogenesis
M. Murata and Y. Miyoshi 138
Growth Inhibition of Hepatoma Cells by Type 1 Interferons: Modification by
Mutations in the Interferon Regulatory Factor 1 Gene
H. Saito, S. Tada, K. Wakabayashi, T. Takagi, N. Nakamoto,
S. Kurita, and H. Ishii 142
Growth Inhibition of Pancreatic Cancer Cell Lines by Ligand Activation
of Nuclear Hormone Receptors Through Up Expression of WAFl/CIPl/p21
S. Kawa and K. Kiyosawa 147
X Contents
Part 7 The Role of Antigen Presenting Cells in Pathophysiology
Immunopathological Features of Granuloma Formation in the Intestinal
Mucosa of Patients with Crohn's Disease
T. Matsumoto, S. Nakamura, J. Hara, Y. Jinno, Y. Sawa, N. Oshitani,
K. Higuchi, T. Arakawa, Y. Nishiguchi, K. Hirakawa, H. Otani,
and H. Nagura 155
Helicobacter pylori and AT Methyl W nitro N nitrosoguanidine Induction of
Dendritic Cell Infiltration of the Pyloric Mucosa of Mongolian Gerbils
M. Oka, C. Furihata, M. Ichinose, N. Yahagi, Y. Shimizu,
H. Kurakata, A. Tateishi Niihata, M. Fujishiro, Y. Sakaki, and
M. Omata 160
Cytotoxic Effect of Bone Marrow Derived Dendritic Cells
H. Shimamura, F. Motoi, J. Yamauchi, K. Shibuya, M. Sunamura,
K. Takeda, and S. Matsuno 167
Autoimmune Mechanisms of Cancer Associated Paraneoplastic
Syndromes: A Review
T. Nishida 171
Antitumor Activity Against Gastrointestinal and Hepatocellular
Carcinoma Induced by Immunization with Fusion of Dendritic and
Carcinoma Cells in Mice
S. Homma, T. Iinuma, G. Toda, T. Ohno, and D. Kufe 175
Part 8 The Pathophysiology of Inflammatory Bowel Disease
Essential Role for Interleukin 6 in the Pathogenesis of Crohn's Disease
H. Ito and T. Kishimoto 183
Activation of Nuclear Factor kB in Dextran Sulfate Sodium Induced Colitis
in Mice and Their Inhibition by Phenyl N ferf Butylnitrone
T. Takagi, Y. Naito, T. Yoshikawa, and Y. Kotake 187
Essential Roles for Th2 Type Responses in Chronic Intestinal Inflammation
T. Dohi 193
Induction of Colitis and Exocrinopathy in Nude Mice Induced by
Immunocompetent Cell Transfer from Murine Retrovirus Infected Mice
K. Suzuki, Y. Baba, H. Suriki, H. Kawachi, F. Shimizu, and
H. Asakura 197
Potential Role of Mucosal Addressin Cell Adhesion Molecule 1 in
Inflammatory Bowel Diseases
S. Kato, R. Hokari, and S. Miura 201
Contents XI
Anti Saccharmomyces cerevisiae Antibody in Inflammatory Bowel Disease
N. Oshitani, K. Higuchi, T. Matsumoto, and T. Arakawa 205
Reactive Oxygen Species and Colonic Epithelial Cell Apoptosis in
Ulcerative Colitis
A. Hayashi, T. Kitahora, and H. Ono 208
Part 9 NSAID lnduced Gastric Lesions
Effect of Antiulcer Drugs for Treatment of Nonsteroidal Antiinflammatory
Drug Induced Ulcers
Y. Mizokami, T. Shiraishi, T. Otsubo, Y. Kariya, H. Nakamura,
K. Narushima, and T. Matsuoka 215
Role of Intravascular Neutrophils in the Pathogenesis of Aspirin Induced
Gastric Mucosal Injury
N. Yoshida and T. Yoshikawa 219
Mucin Secretion Evoked by Prostaglandin E2 in Guinea Pig Antral
Mucous Cells: Role of EP1/EP4 Receptors
A. Ohnishi, C. Shimamoto, T. Nakahari, S. Fujiwara, Y. Nakahata,
K. Kojima, and K. Katsu 224
Effects of Indomethacin and NS 398 on Acid Induced E Cadherin Surface
Expression in Rat Gastric Epithelial Cells
Y. Takezono, T. Joh, M. Sasaki, H. Kataoka, K. Senou, N. Okayama,
Y. Yokoyama, and M. Itoh 229
Roles of Reactive Nitrogen Species in Helicobacter Related Carcinogenesis
S. Tsuji, A. Kimura, M. Hori, and S. Kawano 233
Interaction Between Helicobacter pylori Infection and NSAID Use
A. Shiotani and D.Y. Graham 237
Interrelations of Nonsteroidal Antiinflammatory Drugs, H. pylori
Infection, and Gastric Damage
S. Futagami, T. Hiratsuka, K. Wada, A. Tatsuguchi, T. Tsukui,
K. Miyake, Y. Shinji, T. Iizumi, K. Shinoki, T. Akamatsu, M. Hosone,
C. Sakamoto, and M. Kobayashi 242
Part 10 Prevention of Disease by Modulation of Microcirculation
Microvascular Leukocyte Activation and Apoptosis in Helicobacter
pylori Colonized Gastric Mucosa
H. Suzuki, K. Yamabe, M. Miyazawa, S. Miura, M. Suzuki, and
H. Ishii 249
XII Contents
Alteration of Gastric Microcirculatory Architecture During Healing of
Acetic Acid Induced Ulcer and Helicobacter pylori Infection
M. Nakamura, H. Matsui, K. Tsuchimoto, and H. Ishii 257
Cyclooxygenase and Colon Cancer
M. Tsujii, S. Tsuji, and S. Kawano 263
Contribution of Colon Cancer Cells to Mesenchymal Cells in the
Formation of Hepatic Metastasis
N. Yamada, S. Shimizu, S. Takatsuka, M. Yashiro, T. Sawada,
M. Ohira, T. Ishikawa, H. Nishino, K. Kaneda, and K. Hirakawa 267
Hepatic Microcirculation in Massive Liver Necrosis and Liver Regeneration
S. Mochida and K. Fujiwara 272
Prevention of Hepatic Ischemia/Reperfusion Injury by Microcirculatory
Regulation: Application to Liver Transplantation
M. Shimazu, G. Wakabayashi, M. Tanabe, S. Kawachi, K. Iwata,
and M. Kitajima 277
Genetic Manipulation of Sinusoidal Endothelial Cells
Y. Takei, A. Maruyama, T. Akaike, and N. Sato 283
Controlling Tumor Microenvironment by the Antiangiogenesis Strategy
M. Sunamura, D.G. Duda, L. Lozonschi, S. Libo, K. Takeda, and
S. Matsuno 287
Pancreatic Blood Flow in Chronic Alcoholic Pancreatitis
T. Tanaka, T. Fujii, Y. Matsugu, and K. Dohi 290
Part 11 Hepatic Regeneration Update
The Role of Hepatic Oval Cells in Hepatic Regeneration:
Possible Clinical Applications
S. Matsusaka and A. Toyosaka 297
Hepatoma Derived Growth Factor: Involvement in Liver Development
and Regeneration
H. Enomoto, Y. Kishima, K. Yoshida, and H. Nakamura 302
Tumor Necrosis Factor and Liver Regeneration
Y. Yamada, N. Fausto, and H. Moriwaki 306
Contents XIII
Heparin Binding EGF Like Growth Factor: Hepatotrophic Factor in
Liver Regeneration
S. Kiso, S. Tamura, and S. Kawata 312
Effects of Growth Stimulatory and Inhibitory Factors on Signal
Transduction of Cultured Rat Hepatocyte and the Regulation of Cyclin
Dl Transcription
A. Moriuchi, A. Ido, S. Hirono, T. Nakama, M. Ochiai, T. Hori,
K. Hayashi, and H. Tsubouchi 317
Significance of the Relation Between Hepatocyte Growth Factor and
Transforming Growth Factor a in Hepatocyte Proliferation
T. Tomiya and K. Fujiwara 321
Part 12 Hepatic Fibrosis Research and Its Application to Therapy
Transcriptional Regulation of Type I Collagen Gene Expression by
Transforming Growth Factor (3 and Smad Proteins
Y. Inagaki, T. Nemoto, and A. Nakao 327
Clinical Usefulness of Plasma MMP 9 Assay Compared with the Plasma
MMP 2 Assay in Patients with Chronic Liver Disease
Y. Murawaki, Y. Ikuta, K. Okamoto, M. Koda, and H. Kawasaki 331
Molecular Mechanisms of Matrix Metalloproteinase 1 Gene Expression
in Hepatic Stellate Cells
S. Hozawa, H. Suzuki, S. Kagawa, A. Higuchi, T. Watanabe,
H. Ishii, and I. Okazaki 336
Molecular Analysis of Stellate Cells Activation by Proteomics
N. Kawada 340
Tissue Inhibitor of Metalloproteinase 1: Strong Promotion of Liver
Fibrosis Development in the Transgenic Mouse Model
H. Yoshiji, S. Kuriyama, and H. Fukui 344
Antioxidant and Antiapoptotic Activities of a Tissue Specific Selective
Estrogen Receptor Modulator, Idoxifene, in Rat Fibrotic Liver and
Cultured Rat Hepatocytes
I. Shimizu, T. Omoya, Y. Zhou, M. Itonaga, H. Inoue, G. Lu,
Y. Okamura, M. Shono, H. Honda, and S. Ito 350
Blockade of TGFP Signaling: Prevention of Fibrosis/Dysfunction and
Enhancement of Hepatocyte Regeneration in Injured Liver
H. Ueno and T. Nakamura 356
XIV Contents
Protease Inhibitors: Suppression of Activation of Hepatic Stellate Cells
by Inhibiting TGF(3 Generation
M. Okuno, K. Akita, S. Adachi, H. Moriwaki, and S. Kojima 361
Plasma Transforming Growth Factor pl: A Useful Marker for Hepatic
Fibrosis in Chronic Hepatitis C
N. Ito and S. Kawata 364
Key Word Index 367 |
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institution | BVB |
isbn | 4431703020 |
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spellingShingle | Trends in gastroenterology and hepatology millenium 2000 Digestive System Diseases Congresses Digestive organs Diseases Congresses Leberkrankheit (DE-588)4034937-8 gnd Verdauungskanal (DE-588)4078786-2 gnd Krankheit (DE-588)4032844-2 gnd |
subject_GND | (DE-588)4034937-8 (DE-588)4078786-2 (DE-588)4032844-2 (DE-588)1071861417 |
title | Trends in gastroenterology and hepatology millenium 2000 |
title_auth | Trends in gastroenterology and hepatology millenium 2000 |
title_exact_search | Trends in gastroenterology and hepatology millenium 2000 |
title_full | Trends in gastroenterology and hepatology millenium 2000 H. Asakura ... (eds.) |
title_fullStr | Trends in gastroenterology and hepatology millenium 2000 H. Asakura ... (eds.) |
title_full_unstemmed | Trends in gastroenterology and hepatology millenium 2000 H. Asakura ... (eds.) |
title_short | Trends in gastroenterology and hepatology |
title_sort | trends in gastroenterology and hepatology millenium 2000 |
title_sub | millenium 2000 |
topic | Digestive System Diseases Congresses Digestive organs Diseases Congresses Leberkrankheit (DE-588)4034937-8 gnd Verdauungskanal (DE-588)4078786-2 gnd Krankheit (DE-588)4032844-2 gnd |
topic_facet | Digestive System Diseases Congresses Digestive organs Diseases Congresses Leberkrankheit Verdauungskanal Krankheit Konferenzschrift 2000 Niigata |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009430912&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT asakurahitoshi trendsingastroenterologyandhepatologymillenium2000 |