Healthy aging for functional longevity: molecular and cellular interactions in senescence
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2001
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
928 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 389 S. Ill., graph. Darst. |
| ISBN: | 1573312851 157331286X |
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 928
April 2001
HEALTHY AGING FOR
FUNCTIONAL LONGEVITY
MOLECULAR AND CELLULAR
INTERACTIONS IN SENESCENCE
Editors
Sang Chul Park, Eun Seong Hwang, Hyun Sook Kim,
and Woong Yang Park
Conference Organizers
Hyon E. Choy, Woong Yang Park, Bok Ghee Han,
In Kwon Chung, Cheol Ho Kim, Eun Sung Hwang, In Kyung Lim,
Hyun Sook Kim, and Hae Young Chung
Advisory Board
Byung Pal Yu, Denham Harman, Kenichi Kitani,
mohsen meydani, and imre zs. nagy
This volume is the result of a conference entitled Healthy Aging for Functional Longev¬
ity: Molecular and Cellular Interactions in Senescence held by the International Asso¬
ciation of BioMedical Gerontology during February 2000, in Kyongju, South Korea.
CONTENTS
Preface. By Sang Chul Park xi
Part I. Main Theme of Current Aging Research
Aging: Overview. By Denham Harman 1
Protein Oxidation in Aging and Age Related Diseases. By Earl R. Stadtman . 22
Stress Resistance by Caloric Restriction for Longevity. By BYUNG P. Yu AND
Hae Young Chung 39
Part II. Biomedical Changes Associated with Aging
Protein Glycation: Creation of Catalytic Sites for Free Radical Generation.
By Moon B. Yim, Hyung Soon Yim, Cheolju Lee, Sa Ouk Kang,
and P. Boon Chock 48
Implications of Protein Degradation in Aging. By Sataro Goto,
Ryoya Takahashi, Atsushi Kumiyama, Zsolt Radak,
Toshiaki Hayashi, Masaki Takenouchi, and Ryoichi Abe 54
Transglutaminase Mediated Crosslinking of Specific Core Histone Subunits
and Cellular Senescence. By Jae Hong Kim, Hyon E Choy,
Kang Hoon Nam, and Sang Chul Park 65
Proteome and Proteomics for the Research on Protein Alterations in Aging. By
Tosifusa Toda 71
Attenuation of EGF Signaling in Senescent Cells by Caveolin. By
Woong Yang Park, Kyung A Cho, Jeong Soo Park,
Deok In Kim, and Sang Chul Park 79
Part III. Genomic Instability in Aging
BRCA1 Gene Sequence Variation in Centenarians. By Jan Vug, Thomas
Perls, Claudio Franceschi, and Nathalie J. van Orsouw 85
Increases of Mitochondrial Mass and Mitochondrial Genome in Association
with Enhanced Oxidative Stress in Human Cells Harboring 4,977 BP
Deleted Mitochondrial DNA. By Yau HUEI Wei, Cheng Feng Lee,
Hsin Chen Lee, Yi Shing Ma, Chia Wen Wang, Ching You Lu,
and Cheng Yoong Pang 97
DNA Polymerase |} May Be the Main Player for Defective DNA Repair in
Aging Rat Neurons. By Kalluri Subba Rao, V.V. Annapurna, and
N.S. Raji 113
Premature Aging and Predisposition to Cancers Caused by Mutations in RecQ
Family Helicases. By YASUHIRO FURUICHI 121
Health Span and Life Span in Transgenic Mice with Modulated DNA Repair.
By Christi A. Walter, Zi Qiang Zhou, Drwi Manguino,
Yuji Ikeno, Robert Reddick, James Nelson, Gabriel Intano,
Damon C. Herbert, C. Alex McMahan, and Martha Hanes 132
Part IV. Cellular Maintenance and Stress Response
Inhibition Mechanisms of Bioflavonoids Extracted from the Bark of Pinus
maritima on the Expression of Proinflammatory Cytokines. By
Kyung Joo Cho, Chang Hyun Yun, Lester Packer,
and An Sik Chung 141
Gene Expression and Regulation in the Extended Longevity Phenotypes of
Drosophila. By ROBERT ARKING 157
Impairment of Learning and Memory in Rats Caused by Oxidative Stress and
Aging, and Changes in Antioxidative Defense Systems. By KOJI FUKUl,
Koji Onodera, Tadashi Shinkai, Shozo Suzuki, and Shiro Urano 168
Translocational Inefficiency of Intracellular Proteins in Senescence of Human
Diploid Fibroblasts. By In Kyoung Lim, Kwang Won Hong,
In Hae Kwak, Gyesoon Yoon, and Sang Chul Park 176
Oxidative Stress and Neurodegeneration in Prion Diseases. By Jae Il KlM,
Seung Il Choi, Nam Ho Kim, Jae Kwang Jin, Eun Kyoung Choi,
Richard I. Carp, and Yong Sun Kim 182
On the True Role of Oxygen Free Radicals in the Living State, Aging, and
Degenerative Disorders. By IMRE Zs. Nagy 187
Cellular and Molecular Pathogenic Mechanisms of Insulin Dependent
Diabetes Mellitus. By Ji WON YOON and Hee Sook Jun 200
Part V. Practical Approach for Functional Longevity
Capacity for Recovery and Possible Mechanisms in Immobilization Atrophy
of Young and Old Animals. By N. Zarzhevsky, O. Menashe,
E. Carmeli, H. Stein, and A.Z. Reznick 212
Nutrition Interventions in Aging and Age Associated Disease. By
Mohsen Meydani 226
Exercise at Old Age: Does It Increase or Alleviate Oxidative Stress? By
Li Li Ji 236
Do Antioxidant Strategies Work against Aging and Age associated
Disorders? Propargylamines: A Possible Antioxidant Strategy. By
Kenichi Kitani, Chiyoko Minami, Takako Yamamoto,
Wakako Maruyama, Setsuko Kanai, Gwen O. Ivy,
and Maria Cristina Carrillo 248
Antioxidant and Immunostimulating Activities of the Fruiting Bodies of
Paecilomyces japonica, a New Type of Cordyceps sp. By Kuk Hyun
Shin, Soon Sung Lim, Sang Hyun Lee, Yeon Sil Lee,
and Sae Yun Cho 261
A New Function of Green Tea: Prevention of Lifestyle related Diseases. By
Naoko Sueoka, Masami Suganuma, Eisaburo Sueoka,
Sachiko Okabe, Satoru Matsuyama, Kazue Imai, Kei Nakachi,
AND HlROTA FUJIKI 274
Anti aging and Health promoting Constituents Derived from Traditional Ori¬
ental Herbal Remedies: Information Retrieval Using the TradiMed 2000
DB.fiylL Moo Chang 281
Part VI. Calorie Restriction and Longevity
Caloric Restriction in Primates. By M. A. Lane, A. Black, A. Handy,
E.M. Tilmont, D. K. Ingram, and G. S. Roth 287
Calorie Restriction Enhances the Expression of Key Metabolic Enzymes
Associated with Protein Renewal during Aging. By Stephen R. Spindler 296
Caloric Restriction in Primates and Relevance to Humans. By
George S. Roth, Donald K. Ingram, and Mark A. Lane 305
Aging and Caloric Restriction in Nonhuman Primates: Behavioral and in Vivo
Brain Imaging Studies. By Donald K. Ingram, Svetlana Chefer,
John Matochik, Tammy D. Moscrip, James Weed,
George S. Roth, Edythe D. London, and Mark A. Lane 316
The Inflammation Hypothesis of Aging: Molecular Modulation by Calorie
Restriction. By Hae Young Chung, Hyon Jeen Kim,
Jung Won Kim, and Byung Pal Yu 327
Panel Discussion: Perspectives in Aging Research in the New Millennium. By
Sang Chul Park, Chair 336
Part VII. Poster Papers
A Thermolabile Variant of Methylenetetrahydrofolate Reductase Is a Deter¬
minant of Hyperhomocyst(e)inemia in the Elderly. By JUN HYUN YOO .. 344
Age related Increase in the Expression of Heat Shock Protein Genes in the
Tissues of Unstressed Rats. By Ryoya Takahashi and Sataro Goto 345
Amyloid (3 Peptide 25 35 Fragment Modulates the Expression of the
Mitochondrial Cytochrome Oxidase Gene. By Bok Ghee Han,
Eun Hye Han, Jeung Yeub Ahn, and Jungsoon Park 346
Analysis of the Cell Distribution of Endogenous Murine Leukemia Virus in
the Brains of SAMR1 and SAMP8 Mice. By Byung HOON Jeong,
Jae Kwang Jin, Eun Kyoung Choi, H.C. Meeker, Christine A.
Kozak, Richard I Carp, and Yong Sun Kim 347
Analysis of Traditional Korean Food Patterns According to the Healthy
Longevity Diet Based on the Database of Favorite Korean Foods. By
Mee Sook Lee, Mee Kyung Woo, Chung Shil Kwak, Se In Oh,
and Sang Chul Park 348
Analysis of Proteins in Aged Rat Kidney: The Effect of Calorie Restriction.
By Hyon Jeen Kim, Hyeon Young Jeong, Byung Pal Yu,
Sataro Goto, and Hae Young Chung 349
Analysis of Redox Status in Serum during Aging. By Jung Won Kim,
Jae Kyung No, Byung Pal Yu, and Hae Young Chung 350
Animal Model for Alzheimer s Disease by PS2 Gene Transfer. By Dae Youn
Hwang, Kap Ryong Chae, Tae Surk Kang, Dong Hwan Shin,
In Surk Jang, Jin Hee Hwang, Yeon Ju Kim, Joon Yong Cho,
Bum Jin Kim, Yong Kyu Kim, and Jung Sik Cho 351
Changes in Growth Factor induced Signal Transduction during the Aging
Process of Human Primary Fibroblasts. By Eui Ju Yeo AND
Chang Mo Kang 352
Contribution of Cyclooxygenase to Age related Oxidative Stress. By
Hyon Jeen Kim, Byung Pal Yu, Mi Ae Yu, Kyu Won Kim,
Jae Suk Woo, and Hae Young Chung 353
Control of Mitochondrial Redox Balance by the Mitochondrial NADP+
dependent Isocitrate Dehydrogenase. By Tae Lin Huh, Seung Hee Jo,
Mi Kyung Sohn, Su Min Lee, In Hwang Song, Ho Jin Koh,
Yong Ou Kim, and Jeen Woo Park 354
The Pro and Antioxidant Role of Glutathione in Selenite induced Oxidative
Stress and Apoptosis. By Han Ming Shen, Cheng Feng Yang,
Jin Liu, and Choon Nam Ong 355
Effects of Aging on Aldosterone Secretion in Rat Zona Glomerulosa Cells. By
Mei Mei Kau, Jiann Jong Chen, and Paulus S. Wang 356
Evidence for Differential Structure and Function of Hsp70 Family Members,
Mot 1 and Mot 2, in Control of Cellular Senescence. By YOUJI Mrrsui,
Renu Wadhwa, Syuichi Takano, and Sunil C. Kaul 357
Expression of Growth Related Genes in the Tissues of Aged Rat Brain. By
Deok Kyu An, Seon Gil Do, Jun Gyo Suh, Jae Bong Park, and
Jae YongLee 358
Expression of Peroxiredoxin in the Skin and Change of Peroxiredoxin by Ul¬
traviolet B Irradiation: A Possible Antioxidant Role against Oxidative
Stress in the Skin. By Seung Chul Lee, Jung Eun Lee, Jee Bum Lee,
Young Pio Kim, and Ho Zoon Chae 359
Genetic Polymorphism of Presenilin 1 Gene and Apolipoprotein E in Korean
Elderly with Dementia. By Jung Eun Park and Kyung Hea Cho .... 361
Impact of Growth Hormone Suppression in the Aging Process and Prelimi¬
nary Longevity Analysis. By Isao Shimokawa, Yoshikazu Higami,
Kurumi Yanagihara Outa, Kenji Tanaka, Tomoshi Tuchiya,
Takahito Kondo and Shinji Goto 362
Increased Expression of Calsenilin in the Brains of Scrapie infected Mice. By
Jin Kyu Choi, Hyun Pil Lee, Eun Kyoung Choi, Jae Kwang Jin,
Hyoung Gon Lee, Wilma Wasco, Joseph D. Buxbaum,
Richard I. Carp, and Yong Sun Kim 363
Induction of Cellular Senescence in Cervical Cancer Cells by Inhibition of
HPV Oncogene Expression. By Chan Jae Lee and Eun Seong Hwang 364
Induction of Senescence like Phenotype by an Alkylating Agent, Methyl
Methanesulfonante, in Human Diploid Fibroblast. By YOUSIN Suh,
Deok In Kim, Jeong Soo Park, Woong Yang Park, and
Sang Chul Park 365
Investigation on Natural Peroxynitrite Scavengers. By Jl SUNG YOON,
Byung Pal Yu, and Hae Young Chung 366
Involvement of Caspases in Cell Death Induced by Selenium Compounds in
HL 60 Cells. By Uhee Jung, Tae Ho Kim, and An Sik Chung 367
Lowered 8 Hydroxyguanine Glycosylase Activity in Senescence accelerated
Mice due to a Single base Mutation. By JEONG YuN CHOI, Hun Sik
Kim, Dong Wook Lee, and Myung Hee Chung 368
Melatonin related Compounds Have High Free Radical Scavenging Activity.
By Ryung Yang, Hae Young Chung, Dong Bum Shin, Tae Yeon
Cho, and Seung Hyun Yang 369
Metabolic Modulation of Cellular Redox Potential Can Improve Cardiac
Recovery from Ischemia Reperfusion Injury. By HEUN Soo KANG,
Jong Wan Park, Yang Sook Chun, Myung Suk Kim, and
Sang Chul Park 370
New Directions in Communicating Better Nutrition to Older Adults. By
Georgia Sue Guldan and Wendy Wai Hing Hui 371
Nitric Oxide Is Implicated in Apoptotic Cell Death Induced by H2O2 in C6
Cells. By Young II Lee, Jungsoon Park, Young Hee Lee, and
Bok Ghee Han 372
Overexpression of Calsenilin in Sporadic Alzheimer s Disease Brain. By
Jae Kwang Jin, Jin Kyu Choi, Jae II Kim, Hyoung Gon Lee,
Wilma Wasco, Joseph D. Buxbaum, Richard I. Carp,
Yong Sun Kim, and Eun Kyoung Choi 373
Oxidative Stress Associated Antioxidant Enzyme and Neuroendocrine Mark¬
ers in Dementia. By Heui Og Kim, Hye Won Seo, Jung Eun Park,
Kyung Hea Cho, and In Sung Kim 374
p38 Mitogen activated Protein Kinase Is Involved in F^C^ induced Phospho
lipase D Activation in Vascular Smooth Muscle Cells. By Eung Gook
Kim, Eun Young Shin, Do Sik Min, Byoung Hee Park,
Kyung Sun Shin, Min Soo Hyun, Ji Cheol Shin, Hee Yul Ahn,
Roger J. Davis, and Seung Ryul Kim 376
Photoaging in Asian Skin: New Grading System and the Influence of
Environmental Factors. By Jin Ho Chung, Seong Hun Lee,
Choon Shik Yoon, and Hee Chul Eun 377
Plasma Concentrations of an Endogenous Nitric Oxide Synthase Inhibitor,
NG,NG Dimethylarginine: A Novel Risk Factor for Cerebral Infarction
in the Elderly. By Jun Hyun Yoo and Sung Chang Lee 378
Protection of Mitochondria Permeability Transition by Dihydroxybenzalde
hyde against Hydroxyl Radicals. By Hae Young Chung, Hyon Jeen
Kim, Young Hwan Yang, Won Chul Choi, Hye Jin Park, Jae Sue
Choi, Chang Mo Kang, and Sang Chul Park 379
Risk Factors for Total Mortality in Centenarians in Aichi Prefecture, Japan. By
Kiyoko Yagyu, Shogo Kikuchi, and Hisashi Tauchi 380
The Activation Mechanisms of NF kB and Inflammatory Enzymes during
Aging. By Hyun Joo Kwon, Hyon Jeen Kim, Min Ju Kang, Ryoya
Takahashi, Sataro Goto, Byung Pal Yu, and Hae Young Chung 381
Vitamin and Mineral Supplement Use among Independent living Korean and
American Older Adults. By Seung Youn Hong 382
Vitamin D and Estrogen Receptor Gene Polymorphism and Their Interaction
Associated with Bone Mineral Density in Korean Postmenopausal Wom¬
en. By In Soon Kwon, Taiwoo Yoo, Byung Joo Park, Heung Sik
Kang, Chang Mo Kang, In Kyu Kim, Sang Hoon Bae, Hyun Chan
Cho, Haeng Shin Lee, and Cho Il Kim 384
Vitamin E Dose Associated Alterations in Mouse Immune Function. By
Hyun Sook Kim, Ji Hye Lee, and You Sook Lee 385
Index of Contributors 387
Financial assistance was received from:
• FEDERATION OF KOREAN GERONTOLOGICAL SOCIETIES
• KOREA SCIENCE ENGINEERING FOUNDATION
• KOREA RESEARCH FOUNDATION
• KOREA RESEARCH FOUNDATION FOR HEALTH SCIENCE
• SEOUL NATIONAL UNIVERSITY
The New York Academy of Sciences believes it has a responsibility to provide an open
forum for discussion of scientific questions. The positions taken by the participants in
the reported conferences are their own and not necessarily those of the Academy. The
Academy has no intent to influence legislation by providing such forums.
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| genre | (DE-588)1071861417 Konferenzschrift 2000 Kyŏngju gnd-content |
| genre_facet | Konferenzschrift 2000 Kyŏngju |
| id | DE-604.BV013789019 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:52:00Z |
| institution | BVB |
| isbn | 1573312851 157331286X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009426382 |
| oclc_num | 45757856 |
| open_access_boolean | |
| owner | DE-12 DE-20 DE-19 DE-BY-UBM |
| owner_facet | DE-12 DE-20 DE-19 DE-BY-UBM |
| physical | XII, 389 S. Ill., graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | New York Acad. of Sciences |
| record_format | marc |
| series | Annals of the New York Academy of Sciences |
| series2 | Annals of the New York Academy of Sciences |
| spelling | Healthy aging for functional longevity molecular and cellular interactions in senescence ed. by Sang Chul Park ... New York, NY New York Acad. of Sciences 2001 XII, 389 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 928 Longévité - Congrès Moleculaire biologie gtt Veroudering (biologie, psychologie) gtt Vieillissement - Aspect moléculaire - Congrès Aging Molecular aspects Congresses Aging physiology Congresses Cell Aging physiology Congresses Longevity Congresses Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Langlebigkeit (DE-588)4166707-4 gnd rswk-swf Altern (DE-588)4068596-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2000 Kyŏngju gnd-content Langlebigkeit (DE-588)4166707-4 s DE-604 Altern (DE-588)4068596-2 s Molekularbiologie (DE-588)4039983-7 s Park, Sang-Chul Sonstige oth Annals of the New York Academy of Sciences 928 (DE-604)BV002532608 928 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009426382&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Healthy aging for functional longevity molecular and cellular interactions in senescence Annals of the New York Academy of Sciences Longévité - Congrès Moleculaire biologie gtt Veroudering (biologie, psychologie) gtt Vieillissement - Aspect moléculaire - Congrès Aging Molecular aspects Congresses Aging physiology Congresses Cell Aging physiology Congresses Longevity Congresses Molekularbiologie (DE-588)4039983-7 gnd Langlebigkeit (DE-588)4166707-4 gnd Altern (DE-588)4068596-2 gnd |
| subject_GND | (DE-588)4039983-7 (DE-588)4166707-4 (DE-588)4068596-2 (DE-588)1071861417 |
| title | Healthy aging for functional longevity molecular and cellular interactions in senescence |
| title_auth | Healthy aging for functional longevity molecular and cellular interactions in senescence |
| title_exact_search | Healthy aging for functional longevity molecular and cellular interactions in senescence |
| title_full | Healthy aging for functional longevity molecular and cellular interactions in senescence ed. by Sang Chul Park ... |
| title_fullStr | Healthy aging for functional longevity molecular and cellular interactions in senescence ed. by Sang Chul Park ... |
| title_full_unstemmed | Healthy aging for functional longevity molecular and cellular interactions in senescence ed. by Sang Chul Park ... |
| title_short | Healthy aging for functional longevity |
| title_sort | healthy aging for functional longevity molecular and cellular interactions in senescence |
| title_sub | molecular and cellular interactions in senescence |
| topic | Longévité - Congrès Moleculaire biologie gtt Veroudering (biologie, psychologie) gtt Vieillissement - Aspect moléculaire - Congrès Aging Molecular aspects Congresses Aging physiology Congresses Cell Aging physiology Congresses Longevity Congresses Molekularbiologie (DE-588)4039983-7 gnd Langlebigkeit (DE-588)4166707-4 gnd Altern (DE-588)4068596-2 gnd |
| topic_facet | Longévité - Congrès Moleculaire biologie Veroudering (biologie, psychologie) Vieillissement - Aspect moléculaire - Congrès Aging Molecular aspects Congresses Aging physiology Congresses Cell Aging physiology Congresses Longevity Congresses Molekularbiologie Langlebigkeit Altern Konferenzschrift 2000 Kyŏngju |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009426382&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
| work_keys_str_mv | AT parksangchul healthyagingforfunctionallongevitymolecularandcellularinteractionsinsenescence |