New drugs for asthma, allergy and COPD: 72 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Karger
2001
|
| Schriftenreihe: | Progress in respiratory research
31 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 389 S. Ill., graph. Darst. |
| ISBN: | 3805568622 |
Internformat
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Contents
VIII Foreword
IX Preface
General Aspects
2 The Need for New Therapy
Barnes, P.J.; Hansel, T.T. (NHLI, Imperial College, London)
6 Current Therapy for Asthma
Barnes, P.J. (NHLI, Imperial College, London)
11 Current Therapy for COPD
Pauwels, R. (Ghent University Hospital, Ghent)
15 Pharmacogenetics
Hall, I.P. (University Hospital, Nottingham); Hansel, T.T.
(NHLI, Imperial College, London)
20 Delivery of Biologies to the Lung
Cipolla, D.; Farr, S.; Gonda, I.; Otulana, B.
(Aradigm Corporation, Hayward, Calif.)
24 Immunopathology: Comparison of COPD and
Asthma
Jeffery, P.K. (NHLI, Imperial College, London)
30 Monitoring Lung Function
Pride, N. (NHLI, Imperial College, London)
35 Airway Hyperresponsiveness
Sterk, P.J. (Leiden University Medical Centre, Leiden)
39 Airways Remodelling
Holgate, S.T.; Davies, D.E. (University of Southampton,
Southampton)
44 Exhaled Breath Analysis
Kharitonov, S.A.; Barnes. P.J. (NHLI. Imperial College. London)
48 Clinical Studies on New Drugs
Hansel. T.T.: Barnes. P.J. (NHLI. Imperial College. London)
Bronchodilators
54 Bronchodilators: An Overview
Anderson. G.P. (University of Melbourne. Melbourne):
Rabe. K.F. (Leiden University Center. Leiden)
60 Long Acting (^ Agonists
Johnson. M.; Hagan, G.W.E. (GlaxoWellcome, Uxbridge)
64 Single lsomer ^ Agonists
Handley, D.A. (Sepracor, Marlborough. Mass.); Morley, J.
(Haldane Research. Huntingdon); Nelson, H.S. (National Jewish
Medical and Research Center. Denver, Colo.)
68 Dual D2 Dopamine Receptor and (Jj Adrenoceptor
Agonists for the Modulation of Sensory Nerves in
COPD
Newbold, P.; Jackson, D.M.; Young, A.; Dougall, I.G.;
Ince, F.; Rocchiccioli, K.M.S.; Holt, P.R. (AstraZeneca.
Loughborough)
72 Anticholinergics: Tiotropium
Disse, B.; Witek, T.J., Jr. (Boehringer Ingelheim, Ingelheim and
Ridgefield, Conn.)
77 Potassium Channel Openers
Agents for the Treatment of Airway Hyperreactivity
Fozard, J.R.; Manley, P.W. (Novartis Pharma Ltd. Basel)
81 Urodilatin
Forssmann, K.; Meyer, M.; Forssmann. W.G. (CardioPep
Pharma GmbH and IPF Pharmaceuticals GmbH. Hannover)
Steroids
86 Steroids: An Overview
Dahl, R.; Nielsen, L.P. (University of Aarhus, Aarhus)
91 Ciclesonide: An On Site Activated Steroid
Dietzel, K.; Engelstatter, R.; Keller, A. (Byk Gulden
Pharmaceuticals, Konstanz)
94 Soft Steroids
Axelsson, B.; Brattsand. R. (AstraZeneca. Lund)
98 Dissociated Steroids
Brown, T.J.; Belvisi, M.G.; Foster. M.L. (Aventis
Pharmaceuticals. Dagenham)
102 Oestradiol Metabolites
Effects on Airway Remodelling
Stewart. A.G.; Vlahos, R.; Fernandcs. D.J.; Hughes. R.A.
(University of Melbourne. Melbourne)
Leukotriene Inhibitors
108 Leukotriene Inhibitors: An Overview
O'Byrne. P.M. (McMaster University. Hamilton);
Drazen, J.M. (Harvard Medical School. Boston. Mass.)
V
111 Cysteinyl Leukotriene Antagonists
McMillan, R.M. (AstraZeneca, Macclesfield)
115 5 Lipoxygenase Inhibitors
Dahlen, S. E. (Karolinska Institutet, Stockholm)
121 LTB4 Antagonism
Jennewein, H.M.; Anderskewitz, R.; Meade, C.J.; Pairet, M.;
Birke, F. (Boehringer Ingelheim, Ingelheim)
Mediator Inhibitors and Agonists
128 HrAntihistamines
De Vos, C; Rihoux, J.P. (UCB Pharma SA, Brussels)
133 Histamine H3 Antagonists
McLeod, R.L.; Egan, R.W.; Cuss, F.M. (Schering Plough,
Kenilworth, N.J.); Bolser, D.C. (University of Gainesville,
Gainesville, Fla.).; Hey, J.A. (Schering Plough,
Kenilworth, N.J.)
137 Kinin Receptor Antagonists
Meini, S.; Maggi, C.A. (Menarini Ricerche SpA, Florence)
141 Endothelin Antagonists
Hay, D.W.P.; Compton, C.H. (SmithKline Beecham
Pharmaceuticals, King of Prussia, Pa., and Harlow)
145 Tachykinin Antagonists
Hay, D.W.P. (SmithKline Beecham Pharmaceuticals,
King of Prussia, Pa.)
151 Antioxidants
MacNee, W. (University of Edinburgh, Edinburgh)
156 Selective iNOS Inhibitors
Manning, P.T.; Thompson, J.M. (Searle, St. Louis, Mo., and
Skokie, 111.); Currie, M.G. (Sepracor Inc., Marlborough, Mass.)
160 Mucus Regulation
Rogers, D.F. (NHLI, Imperial College, London)
165 P2Y Receptor Agonists
Role in Mucosal Hydration and Mucociliary Clearance
Pendergast, W.; Evans, R. (Inspire Pharmaceuticals, Inc.,
Durham, N.C.)
Protease Inhibitors
170 Tryptase Inhibition
Clark, J.M.; Van Dyke, R.E.; Kurth, M.C. (Axys
Pharmaceuticals, Inc., S. San Francisco, Calif.)
173 Neutrophil Elastase Inhibitors
Smith, R.A. (GlaxoWellcome, Stevenage); Stockley. R.A.
(Queen Elizabeth Hospital, Birmingham); Hodgson, S.T.
(GlaxoWellcome, Stevenage)
177 Macrophage Metalloelastase Inhibitors
Martin. R.L. (Roche Bioscience, Palo Alto, Calif); Shapiro, S.D.
(Washington University, St. Louis, Mo.); Tong, S.E.;
Van Wart, H.E. (Roche Bioscience, Palo Alto, Calif.)
VI Contents
Allergen and IgE Directed Therapies
182 Allergen, IgE and Mast Cell Directed Responses:
An Overview
Larche, M.; Kay, A.B. (NHLI, Imperial College, London)
186 Allergen Immunotherapy
Wilson, D.R.; Durham, S.R. (NHLI, Imperial College, London)
191 Peptide Immunotherapy
Oldfield, W.L.G.; Kay, A.B.; Larche, M. (NHLI, Imperial
College, London)
195 Recombinant Allergens
Valenta, R.; Kraft, D. (University of Vienna, Vienna)
201 Anti lgE Antibody
Boushey, H.A. (University of California, San Francisco, Calif.);
Fick, R. (Genentech, Inc., S. San Francisco, Calif.);
Fahy, J.V. (University of California, San Francisco, Calif.)
206 CD23
Conrad, D.H. (Virginia Commonwealth University, Richmond,
Va.)
T Cell Immunomodulation
212 T Cell Immunomodulation: An Overview
Koulis, A.; Robinson, D.S. (NHLI, Imperial College, London)
217 Costimulatory Molecules in T Cell Activation
Coyle, A.J.; Gutierrez Ramos, J. C. (Millennium
Pharmaceuticals Inc., Cambridge, Mass.)
222 GATA 3: A Th2 Selective Target
Ray, A.; Ray, P. (Yale University, New Haven, Conn.)
226 Mycobacterial Immunization
Agents to Limit Asthma
Hopkin, J.M. (University of Wales, Swansea)
229 CpG Oligodeoxynucleotides
Kline, J.N.; Krieg, A.M. (University of Iowa, Iowa City, Iowa,
and Coley Pharmaceutical Group, Wellesley, Mass.)
233 CD8 T Cells: Potential Therapeutic Targets?
Out, T.A. (Academic Medical Center and
CLB Sanquin Blood Supply Foundation, Amsterdam);
de Pater Huijsen, F.L.; Jansen, H.M. (Academic Medical
Center, Amsterdam); Corrigan, C.J. (Guy's, King's and
St. Thomas' School of Medicine, London)
237 Macrocyclic Immunosuppressants
Keller, T.H.; Hersperger, R.; Delia Cioppa, G. (Novartis,
Horsham and Basel)
Cytokine Directed Therapy
242 Cytokines: An Overview
Chung, K.F. (NHLI, Imperial College, London)
247 TNF Antagonism
McDonnell, N.D.; Abbott, N.M.; Mohler, K.M. (Immunex Corp.,
Seattle, Wash.); Hansel, T.T. (NHLI, Imperial College, London);
Kips, J.C. (Ghent University Hospital, Ghent)
251 GM CSF Antagonists
Williams, W.V. (SmithKline Bcecham. Philadelphia, Pa.)
256 lnterleukin 4 Antagonism
Borish, L. (University of Virginia. Charlottesville. Va.);
Agosti, J.M. (Immunex Corporation. Seattle. Wash.)
260 lnterleukin 13 Antagonism
Donaldson, D.D. (Wyeth Ayerst, Andover. Mass.); Elias. J.A.
(Yale University, New Haven, Conn.); Wills Karp, M. (Johns
Hopkins University, Baltimore. Md.)
265 lnterleukin 5 Antagonism
Leckie, M.J. (NHL1, Imperial College, London); Walker, C.
(Novartis Research Centre, Horsham)
269 lnterleukin 10
Narula, S.; Cuss, F. (Schering Plough Research Institute,
Kenilworth, N.J.)
274 lnterleukin 12, lnterleukin 18 and Interferon y
Bryan, S. (NHL1, Imperial College, London); Kobayashi, M.
(Wyeth Ayerst, Andover, Mass.); Sur, S. (University of Texas,
Galveston, Tex.)
Chemokine Receptor Inhibition
280 Chemokines: An Overview
Sabroe, I.; Williams, T.J. (Imperial College, South Kensington)
284 Chemokine Receptors on Th1 and Th2 Cells
Sinigaglia, F. (Roche Milano Ricerche. Milan); Fabbri, L.M.
(University of Modena, Modena); D'Ambrosio, D. (Roche
Milano Ricerche, Milan)
288 CCR 3 Antagonists
Bryan, S.A. (NHLI, Imperial College. London); Ponath. P.D.
(LeukoSite, Inc., Cambridge, Mass.); Wilhelm, R.S. (Roche
Bioscience, Palo Alto. Calif.)
293 lnterleukin 8 Receptor (CXCR2) Antagonists
Sarau, H.M.; Widdowson, K.L.; Palovich. M.R.; White, J.R.;
Underwood, D.C.; Griswold, D.E. (SmithKline Beecham
Pharmaceuticals, King of Prussia, Pa.)
Adhesion Molecule Inhibitors
298 Adhesion Molecule Antagonism: An Overview
Bochner. B.S. (Johns Hopkins University. Baltimore. Md.)
302 Small Molecule VLA 4 Antagonists
Adams, S.P.: Lobb, R.R. (Biogen Inc. Cambridge. Mass.)
306 Selectin Antagonists
Therapeutics for Airway Inflammation
Berens. K.L.; Vanderslice. P.; Dupre. B. Dixon. R.A.F.
(Texas Biotechnology Corporation. Houston. Tex.)
310 ICAM 1 and VCAM 1 Antagonists
Richards. I.M.; Slatter. V.K. (Pharmacia Corporation.
Kalamazoo. Mich.)
Contents
Inhibition of Cell Signalling
316 Eosinophil G Protein Coupled Receptor Signalling:
An Overview
Lindsay, M.A.; Dc Souza, P.M.; Lynch. O.T.: Giembycz. M.A.
(NHLI. Imperial College. London)
321 Phosphodiesterase 4 Inhibitors
Torphy, T.J.; Compton, C.H.; Marks. M.J. (SmithKline
Beecham, King of Prussia, Pa., Harlow. and Collegeville. Pa.);
Sturton, G. (Bayer pic. Slough)
Therapies Acting on Transcription
328 Therapies Acting on Transcription: An Overview
Caramori, G.; Adcock, I.M. (NHLI. Imperial College, London)
332 Chromatin Modification
Urnov, F.D.; Wolffe, A.P. (Sangamo Biosciences, Richmond,
Calif.)
337 Activator Protein 1 and Nuclear Factor Kappa B
Bennett, B.L.; Manning, A.M. (Signal Pharmaceuticals, Inc.,
San Diego, Calif.)
342 Inhibition of p38 MAP Kinase
Underwood, D.C.; Griswold, D.E. (SmithKline Beecham
Pharmaceuticals, King of Prussia, Pa.)
346 STAT6
Role in IL 4 Mediated Signaling
Schaefer, G.; Venkataraman. C; Schindler. U. (Tularik. Inc.
S. San Francisco, Calif.)
350 Retinoids
Belloni, P.N. (Roche Bioscience. Palo Alto. Calif.)
Genetic Therapy
358 Asthma and COPD Genetics and Genomics:
An Overview
Morrison, J.F.J. (AstraZeneca, Macclesfield)
361 Respirable Antisense Oligonucleotides
Nyce, J.W. (EpiGenesis Pharmaceuticals. Inc. Princeton. N.J.)
365 Antisense Therapy
Bennett. C.F. (Isis Pharmaceuticals. Inc. Carlsbad. Calif.)
370 Ribozyme Therapy
Sandberg. J.A.; Lee. P.A.; Usman. N. (Ribozyme
Pharmaceuticals. Inc., Boulder. Colo.)
374 Gene Therapy
Kolb. M.; Gauldie. J. (McMaster University. Hamilton)
379 Author Index
381 Subject Index
388 Abbreviations
VII |
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| id | DE-604.BV013655452 |
| illustrated | Illustrated |
| indexdate | 2024-08-14T00:55:27Z |
| institution | BVB |
| isbn | 3805568622 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009329951 |
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| physical | X, 389 S. Ill., graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
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| publisher | Karger |
| record_format | marc |
| series | Progress in respiratory research |
| series2 | Progress in respiratory research |
| spelling | New drugs for asthma, allergy and COPD 72 tables vol. eds.: Trevor T. Hansel ... Basel [u.a.] Karger 2001 X, 389 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Progress in respiratory research 31 Chronic Obstructive Pulmonary Disease cabt Lung Diseases cabt Asthma cabt Drug Therapy cabt Allergies cabt Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Bronchialasthma (DE-588)4069674-1 gnd rswk-swf Antiasthmatikum (DE-588)4201239-9 gnd rswk-swf Obstruktive Ventilationsstörung (DE-588)4213128-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Obstruktive Ventilationsstörung (DE-588)4213128-5 s Pharmakotherapie (DE-588)4076066-2 s DE-604 Antiasthmatikum (DE-588)4201239-9 s Bronchialasthma (DE-588)4069674-1 s Hansel, Trevor T. 1956- Sonstige (DE-588)172588405 oth Progress in respiratory research 31 (DE-604)BV011558798 31 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009329951&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | New drugs for asthma, allergy and COPD 72 tables Progress in respiratory research Chronic Obstructive Pulmonary Disease cabt Lung Diseases cabt Asthma cabt Drug Therapy cabt Allergies cabt Pharmakotherapie (DE-588)4076066-2 gnd Bronchialasthma (DE-588)4069674-1 gnd Antiasthmatikum (DE-588)4201239-9 gnd Obstruktive Ventilationsstörung (DE-588)4213128-5 gnd |
| subject_GND | (DE-588)4076066-2 (DE-588)4069674-1 (DE-588)4201239-9 (DE-588)4213128-5 (DE-588)4143413-4 |
| title | New drugs for asthma, allergy and COPD 72 tables |
| title_auth | New drugs for asthma, allergy and COPD 72 tables |
| title_exact_search | New drugs for asthma, allergy and COPD 72 tables |
| title_full | New drugs for asthma, allergy and COPD 72 tables vol. eds.: Trevor T. Hansel ... |
| title_fullStr | New drugs for asthma, allergy and COPD 72 tables vol. eds.: Trevor T. Hansel ... |
| title_full_unstemmed | New drugs for asthma, allergy and COPD 72 tables vol. eds.: Trevor T. Hansel ... |
| title_short | New drugs for asthma, allergy and COPD |
| title_sort | new drugs for asthma allergy and copd 72 tables |
| title_sub | 72 tables |
| topic | Chronic Obstructive Pulmonary Disease cabt Lung Diseases cabt Asthma cabt Drug Therapy cabt Allergies cabt Pharmakotherapie (DE-588)4076066-2 gnd Bronchialasthma (DE-588)4069674-1 gnd Antiasthmatikum (DE-588)4201239-9 gnd Obstruktive Ventilationsstörung (DE-588)4213128-5 gnd |
| topic_facet | Chronic Obstructive Pulmonary Disease Lung Diseases Asthma Drug Therapy Allergies Pharmakotherapie Bronchialasthma Antiasthmatikum Obstruktive Ventilationsstörung Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009329951&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV011558798 |
| work_keys_str_mv | AT hanseltrevort newdrugsforasthmaallergyandcopd72tables |