Bioinformatics basics: applications in biological science and medicine
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton, Fla.
CRC Press
2000
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 185 S. Ill., graph. Darst. |
| ISBN: | 0849323754 |
Internformat
MARC
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| 100 | 1 | |a Rashidi, Hooman H. |e Verfasser |4 aut | |
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| 264 | 1 | |a Boca Raton, Fla. |b CRC Press |c 2000 | |
| 300 | |a 185 S. |b Ill., graph. Darst. | ||
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| 650 | 4 | |a Cartes chromosomiques - Informatique | |
| 650 | 2 | |a Informatique médicale | |
| 650 | 7 | |a Médecine - Informatique |2 ram | |
| 650 | 7 | |a Ressources génétiques - Informatique |2 ram | |
| 650 | 4 | |a Sciences de la vie - Informatique | |
| 650 | 7 | |a Sciences de la vie - Informatique |2 ram | |
| 650 | 7 | |a Séquençage des acides nucléiques - Informatique |2 ram | |
| 650 | 4 | |a Biowissenschaften | |
| 650 | 4 | |a Datenverarbeitung | |
| 650 | 4 | |a Automatic Data Processing | |
| 650 | 4 | |a Bioinformatics | |
| 650 | 4 | |a Chromosome Mapping | |
| 650 | 4 | |a Computational Biology | |
| 650 | 4 | |a Gene mapping |x Data processing | |
| 650 | 4 | |a Life sciences |x Data processing | |
| 650 | 4 | |a Sequence Analysis, DNA | |
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Datensatz im Suchindex
| _version_ | 1804128423308689408 |
|---|---|
| adam_text | Contents
Preface
Chapter 1 Introduction to Bioinformatics 1
1.1 Biology and Bioinformatics 1
The Nature of Publicly Funded Research 3
Genomics and Proteomics 6
Metabolic Databases 6
Public and Proprietary Bioinformatics 7
1.2 Computers in Biology and Medicine 9
Computer Algorithms 10
Different Types of Computers for Different Tasks 11
Supercomputers 12
Limitations of Computational Tools: Paradoxical Promise of
the Internet 13
The Need for Computational Tools 15
New Approaches to Scientific Research with Computers 16
1.3 Biological Macromolecules 17
Proteins 17
Protein Structure 20
Protein Folding 22
Protein Functions 25
DNA and RNA Structure 27
Nucleic Acid Structure and Function 27
Genetic Code 29
Genes and Evolution 31
Chapter 2 Databases and Search Tools 33
2.1 Computational Tools and Databases 33
National Center for Biotechnology Information (NCBI) 34
European Bioinformatics Institute (EBI) 44
GenomeNet — Japanese Bioinformatics Servers 54
2.2 Database Mining Tools 66
Sequence Similarity Search Tools: BLAST 66
Pattern Recognition Tools and Databases 80
Chapter 3 Genome Analysis 83
3.1 DNA Cloning and PCR 83
DNA Cloning 84
Transcriptional Profiling 85
Positional Cloning 86
Polymerase Chain Reaction: PCR 87
Sequencing Technologies Under Development 88
Monitoring Sequencing Progress 89
3.2 Computational Tools for DNA Sequence Analysis 90
Database Submissions 91
Data Retrieval 96
Sequence Alignment 99
What a Sequence Reveals About the Biological Function of
a Gene 101
How to Identify a Gene: ORFs and URFs 102
A Word About Redundancy 104
Better Search Engines for Better Computers? 104
3.3 Genome Analysis 107
Genome Organization 107
Mapping the Genome 112
Human Genome Mapping Progress 118
3.4 Functional Genomics 120
Unidentified Reading Frames: URFs 123
Cluster of Orthologous Groups: COGs 124
Chapter 4 Proteome Analysis 129
4.1 Proteomics 129
2 D Page at Expasy 134
Yeast Proteome Database 136
4.2 Metabolic Reconstruction 137
KEGG: Kyoto Encyclopedia of Genes and Genomes 137
The Functional Reconstruction Model 138
E. coli Metabolic Database: EcoCyc 139
Where Should We Be in the Future? 140
Chapter 5 The Computer Revolution in
Neurobiology 143
5.1 Human Brain Project 143
The Influence of Computers in Science 144
Computers in Neurobiology and the Mapping of the Human
Brain 145
From Molecules to Neurodegenerative Diseases 149
5.2 Computer Simulations and Visualization of Molecular Structures.... 154
3 D Visualization 154
The Virtual Doctor: (Virtual and Remote Surgery) 157
5.3 Predictive Biology 159
Protein Structure Prediction 160
Structure Prediction Software 166
Glossary 169
Index 173
|
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| language | English |
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| spelling | Rashidi, Hooman H. Verfasser aut Bioinformatics basics applications in biological science and medicine Hooman H. Rashidi; Lukas K. Buehler Boca Raton, Fla. CRC Press 2000 185 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bio-informatique Biologie informatique Cartes chromosomiques - Informatique Informatique médicale Médecine - Informatique ram Ressources génétiques - Informatique ram Sciences de la vie - Informatique Sciences de la vie - Informatique ram Séquençage des acides nucléiques - Informatique ram Biowissenschaften Datenverarbeitung Automatic Data Processing Bioinformatics Chromosome Mapping Computational Biology Gene mapping Data processing Life sciences Data processing Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd rswk-swf (DE-588)4151278-9 Einführung gnd-content Bioinformatik (DE-588)4611085-9 s DE-604 Bühler, Lukas K. Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009302009&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Rashidi, Hooman H. Bühler, Lukas K. Bioinformatics basics applications in biological science and medicine Bio-informatique Biologie informatique Cartes chromosomiques - Informatique Informatique médicale Médecine - Informatique ram Ressources génétiques - Informatique ram Sciences de la vie - Informatique Sciences de la vie - Informatique ram Séquençage des acides nucléiques - Informatique ram Biowissenschaften Datenverarbeitung Automatic Data Processing Bioinformatics Chromosome Mapping Computational Biology Gene mapping Data processing Life sciences Data processing Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd |
| subject_GND | (DE-588)4611085-9 (DE-588)4151278-9 |
| title | Bioinformatics basics applications in biological science and medicine |
| title_auth | Bioinformatics basics applications in biological science and medicine |
| title_exact_search | Bioinformatics basics applications in biological science and medicine |
| title_full | Bioinformatics basics applications in biological science and medicine Hooman H. Rashidi; Lukas K. Buehler |
| title_fullStr | Bioinformatics basics applications in biological science and medicine Hooman H. Rashidi; Lukas K. Buehler |
| title_full_unstemmed | Bioinformatics basics applications in biological science and medicine Hooman H. Rashidi; Lukas K. Buehler |
| title_short | Bioinformatics basics |
| title_sort | bioinformatics basics applications in biological science and medicine |
| title_sub | applications in biological science and medicine |
| topic | Bio-informatique Biologie informatique Cartes chromosomiques - Informatique Informatique médicale Médecine - Informatique ram Ressources génétiques - Informatique ram Sciences de la vie - Informatique Sciences de la vie - Informatique ram Séquençage des acides nucléiques - Informatique ram Biowissenschaften Datenverarbeitung Automatic Data Processing Bioinformatics Chromosome Mapping Computational Biology Gene mapping Data processing Life sciences Data processing Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd |
| topic_facet | Bio-informatique Biologie informatique Cartes chromosomiques - Informatique Informatique médicale Médecine - Informatique Ressources génétiques - Informatique Sciences de la vie - Informatique Séquençage des acides nucléiques - Informatique Biowissenschaften Datenverarbeitung Automatic Data Processing Bioinformatics Chromosome Mapping Computational Biology Gene mapping Data processing Life sciences Data processing Sequence Analysis, DNA Bioinformatik Einführung |
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