Cancer metastasis: in vitro and in vivo experimental approaches
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2000
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | Laboratory techniques in biochemistry and molecular biology
29 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 358 S. Ill., graph. Darst. |
| ISBN: | 0444823581 0444823727 |
Internformat
MARC
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| 100 | 1 | |a Rusciano, Dario |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Cancer metastasis |b in vitro and in vivo experimental approaches |c D. Rusciano ; D. R. Welch ; M. M. Burger |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier |c 2000 | |
| 300 | |a XII, 358 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Laboratory techniques in biochemistry and molecular biology |v 29 | |
| 650 | 7 | |a Angiogenese |2 gtt | |
| 650 | 7 | |a Beweeglijkheid |2 gtt | |
| 650 | 7 | |a Immunoassay |2 gtt | |
| 650 | 7 | |a Kanker |2 gtt | |
| 650 | 7 | |a Metastasen |2 gtt | |
| 650 | 4 | |a Métastases - Recherche - Méthodologie | |
| 650 | 7 | |a Métastases - Recherche - Méthodologie |2 ram | |
| 650 | 7 | |a Tumoren |2 gtt | |
| 650 | 4 | |a Metastasis |x Research |x Methodology | |
| 650 | 4 | |a Neoplasm Metastasis |x genetics | |
| 650 | 4 | |a Neoplasm Metastasis |x physiopathology | |
| 650 | 0 | 7 | |a Metastase |0 (DE-588)4125915-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Metastase |0 (DE-588)4125915-4 |D s |
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| 700 | 1 | |a Welch, Danny R. |e Verfasser |4 aut | |
| 700 | 1 | |a Burger, Max M. |d 1933-2019 |e Verfasser |0 (DE-588)13357573X |4 aut | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-009211749 | ||
Datensatz im Suchindex
| _version_ | 1804128286346838016 |
|---|---|
| adam_text | Contents
Preface v
Chapter 1. Introduction 1
Chapter 2. Homotypic and Heterotypic Cell Adhesion in
Metastasis 9
2.1. Release of malignant cells from the tumor mass: intercellular
cohesion 10
2.2. Malignant tumor cells in the blood stream: interactions with blood
elements and platelet aggregation 22
2.3. Adhesion to the target organ 29
Chapter 3. Motility, Deformability and Metastasis 65
3.1. Motility and metastasis 65
3.2. The role of active and passive deformability in invasion and
resistance to shear stress forces in the blood stream 90
Chapter 4. ECM Degradation and Invasion 97
4.1. Degradation 98
4.2. Invasion 112
Chapter 5. The Role of Growth Interactions in Cancer
Metastasis 123
5.1. Methods to evaluate growth interactions in vitro 129
5.2. Growth interactions in vivo 154
xi
xii
Chapter 6. Selection of Metastatic Variants 161
6.1. Selection of organ specific metastatic variants 163
6.2. Selection of metastatic variants with enhanced or decreased
metastatic abilities 168
Chapter 7. Genetic Tagging as a Means of Studying Tumor
Progression or Metastasis related Genes .... 185
7.1. Clonal dominance in tumor progression 185
7.2. Visualization of cancer metastasis 189
7.3. Genes controlling the metastatic phenotype: use of gene tags to
identify metastasis related genes 199
Chapter 8. In Vivo Cancer Metastasis Assays 207
8.1. Why study metastasis in vivo? 208
8.2. What defines an appropriate model of metastasis? 209
8.3. Cell lines 210
8.4. Considerations regarding animals 214
8.5. Site of injection 219
8.6. Materials needed 222
8.7. Spontaneous metastasis assay 222
8.8. Experimental metastasis assay 228
8.9. Enumeration of metastases 231
8.10. Statistical considerations 236
8.11. The influence of stress 236
8.12. Concluding remarks 242
Chapter 9. Angiogenesis and Metastasis 243
9.1. The corneal assay for angiogenesis 244
9.2. The chick embryo chorioallantoic membrane assay 252
9.3. Subcutaneous implant assay 263
References 271
Subject Index 349 ;
|
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| author | Rusciano, Dario Welch, Danny R. Burger, Max M. 1933-2019 |
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| discipline | Biologie Medizin |
| edition | 1. ed. |
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| illustrated | Illustrated |
| indexdate | 2024-07-09T18:46:50Z |
| institution | BVB |
| isbn | 0444823581 0444823727 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009211749 |
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| physical | XII, 358 S. Ill., graph. Darst. |
| publishDate | 2000 |
| publishDateSearch | 2000 |
| publishDateSort | 2000 |
| publisher | Elsevier |
| record_format | marc |
| series | Laboratory techniques in biochemistry and molecular biology |
| series2 | Laboratory techniques in biochemistry and molecular biology |
| spelling | Rusciano, Dario Verfasser aut Cancer metastasis in vitro and in vivo experimental approaches D. Rusciano ; D. R. Welch ; M. M. Burger 1. ed. Amsterdam [u.a.] Elsevier 2000 XII, 358 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Laboratory techniques in biochemistry and molecular biology 29 Angiogenese gtt Beweeglijkheid gtt Immunoassay gtt Kanker gtt Metastasen gtt Métastases - Recherche - Méthodologie Métastases - Recherche - Méthodologie ram Tumoren gtt Metastasis Research Methodology Neoplasm Metastasis genetics Neoplasm Metastasis physiopathology Metastase (DE-588)4125915-4 gnd rswk-swf Metastase (DE-588)4125915-4 s DE-604 Welch, Danny R. Verfasser aut Burger, Max M. 1933-2019 Verfasser (DE-588)13357573X aut Laboratory techniques in biochemistry and molecular biology 29 (DE-604)BV005871299 29 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009211749&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Rusciano, Dario Welch, Danny R. Burger, Max M. 1933-2019 Cancer metastasis in vitro and in vivo experimental approaches Laboratory techniques in biochemistry and molecular biology Angiogenese gtt Beweeglijkheid gtt Immunoassay gtt Kanker gtt Metastasen gtt Métastases - Recherche - Méthodologie Métastases - Recherche - Méthodologie ram Tumoren gtt Metastasis Research Methodology Neoplasm Metastasis genetics Neoplasm Metastasis physiopathology Metastase (DE-588)4125915-4 gnd |
| subject_GND | (DE-588)4125915-4 |
| title | Cancer metastasis in vitro and in vivo experimental approaches |
| title_auth | Cancer metastasis in vitro and in vivo experimental approaches |
| title_exact_search | Cancer metastasis in vitro and in vivo experimental approaches |
| title_full | Cancer metastasis in vitro and in vivo experimental approaches D. Rusciano ; D. R. Welch ; M. M. Burger |
| title_fullStr | Cancer metastasis in vitro and in vivo experimental approaches D. Rusciano ; D. R. Welch ; M. M. Burger |
| title_full_unstemmed | Cancer metastasis in vitro and in vivo experimental approaches D. Rusciano ; D. R. Welch ; M. M. Burger |
| title_short | Cancer metastasis |
| title_sort | cancer metastasis in vitro and in vivo experimental approaches |
| title_sub | in vitro and in vivo experimental approaches |
| topic | Angiogenese gtt Beweeglijkheid gtt Immunoassay gtt Kanker gtt Metastasen gtt Métastases - Recherche - Méthodologie Métastases - Recherche - Méthodologie ram Tumoren gtt Metastasis Research Methodology Neoplasm Metastasis genetics Neoplasm Metastasis physiopathology Metastase (DE-588)4125915-4 gnd |
| topic_facet | Angiogenese Beweeglijkheid Immunoassay Kanker Metastasen Métastases - Recherche - Méthodologie Tumoren Metastasis Research Methodology Neoplasm Metastasis genetics Neoplasm Metastasis physiopathology Metastase |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009211749&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV005871299 |
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