Lipoprotein metabolism and atherogenesis:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Tokyo ; Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ;
Springer
2000
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Literaturangaben |
Beschreibung: | XVIII, 283 S. Ill., graph. Darst. : 24 cm |
ISBN: | 443170261X |
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650 | 4 | |a Adipose tissues |x Metabolism |v Congresses | |
650 | 4 | |a Arteriosclerosis |x metabolism |v Congresses | |
650 | 4 | |a Atherosclerosis |x Etiology |v Congresses | |
650 | 4 | |a Lipoproteins |x Metabolism |v Congresses | |
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Datensatz im Suchindex
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adam_text | Contents
Preface V
Organization of Symposium VII
Acknowledgements VIII
Contributors XV
Chapter 1: The Molecular Approach to Risk Factors and Prevention
Lipoprotein Metabolism and Atherogenesis
J. Shepherd and C.J. Packard 3
Role of Lipid Concentrations and Apolipoproteins in Altering ApoB Metabolism
and Promoting Coronary Events
EM. Sacks 12
Long Term Effect of LDL Apheresis on Familial Hypercholesterolemia
Homozygotes
A. Yamamoto, A. Kawaguchi, and M. Harada Shiba 19
Molecular Mechanism of Visceral Obesity
Y. Matsuzawa, T. Funahashi, T. Nakamura, I. Shimomura, and Y. Arita 26
Diabetes and Atherosclerosis
S. Oikawa, T. Naito, H. Kotake, and T. Toyota 34
Chapter 2: The Molecular Basis of Lipoprotein Metabolism (I)
Molecular Genetics and Clinical Features of Japanese Patients with Familial
Hy percholesterolem ia
H. Mabuchi, A. Nohara, J. Koizumi, and K. Kajinami 39
Molecular Analysis of Apolipoprotein A I and E Mutants in Japan
J.Sasaki 44
Novel Mutations of the LDL Receptor Gene in Familial Hypercholesterolemia
Pedigrees in Hokkaido
M. Emi, T. Hirayama, M. Tsuji, and A. Hata 48
IX
I
x I
i
Preheparin Lipoprotein Lipase Mass Might Reflect the Amount of Working I
Lipoprotein Lipase in the Whole Body 1
K. Shirai, T. Murano, H. Watanabe, Y. Miyashita, Y. Itoh, and M. Totsuka 51 j
I
Quantitative Trait Loci (QTLs) for Serum Cholesterol Levels in the Stroke Prone I
Spontaneoulsy Hypertensive Rats (SHRSP) j
T. Gotoda, N. Kato, and Y. Yamori 54
Evidence of Linkage in Familial Combined Hyperlipidemia to Chromosome Iq2 l q23
P. Pajukanta, C. Ehnholm, M. R. Taskinen, and L. Peltonen 56
Molecular Analysis on the LDL Receptors in Two Patients with Homozygous
Familial Hypercholesterolemia
Y. Miyake, T. Yamamura, K. Oi, and H. Hori 59
Common Mutation of 5, 10 Methylenetrahydrofolate Reductase Accelerates
Coronary Artery Disease in Familial Hypercholesterolemia
M. Kawashiri, K. Kajinami, A. Nohara, K. Yagi, A. Inazu, J. Koizumi,
and H. Mabuchi 62
Effect of Troglitazone on Plasma Lipid Metabolism and Lipoprotein Lipase
J. Kobayashi, I. Nagashima, M. Hikita, H. Bujo, K. Takahashi, M. Otabe,
N. Morisaki, and Y. Saito 65
Combination of LPL Gene Exon 9 Ser447 — Ter Nonsense Mutation and Apoe2
Allele Might Contribute to Development of Hypertriglyceridemia
T. Murano, H. Watanabe, Y. Miyashita, Y. Itoh, M. Totuka, and K. Shirai 68
Improvement by Thiazolidinediones of Vascular Endothelial Cell Dysfunction in
Diabetic Patients: A Possible New Physiological Role of PPARy
D. Yamada, K. Kato, S. Midorikawa, W. Satoh, S. Hashimoto, H. Satoh,
K. Tsukamoto, and T. Watanabe 71
Beneficial Effect of Gemfibrozil on LDL Chemicophysical Characteristics
and Oxidizability
H. Yoshida, M. Ayaori, T. Hisada, T. Ishikawa, F. Ohsuzu, and H. Nakamura 74
Inhibitory Effect of HMG CoA Reductase Inhibitors for the Development
and Progression of Intimal Medial Thickness in Carotid Artery in Type 2 Diabetes
Mellitus with Hypercholesterolemia
S. Kobori, T. Takahashi, S. Kodama, T. Takemura, T. Matsumura, M. Sakai,
T. Sasahara, and M. Shichiri 77
Plasma Phosphatidylcholine Hydroperoxide Concentrations in Normal Subjects
and Patients with Hyperlipidemia
Y. Ishigaki, S. Oikawa, M. Kinoshita, K. Hayasaka, A. Sekikawa, T. Nagashima,
T. Toyota, and T. Miyazawa . 80
XI
Chapter 3: The Molecular Basis of Lipoprotein Metabolism (II)
Lipid Transfer Proteins and Receptors in HDL Metabolism
A.R. Tall, X. C. Jiang, N. Wang, T. Arai, and D. Silver 85
PPARs and Atherosclerosis
I.P. Torra, J. C. Fruchart, and B. Staels 88
Molecular Basis of Cellular Cholesterol Efflux and Regulation of Plasma HDL Level
S. Yokoyama, M. Tsujita, and S. Dohmae 96
Roles of Apolipoprotein E Receptors in Lipoprotein Metabolism
T.T. Yamamoto, Y. Inagaki, R.X. Ioka, S.Z. Yoshioka, K. Magoori, M. J. Kang,
Y. Cho, A.Z. Nakano, Q. Liu, T. Fujino, and D. H. Kim 104
The Structure and Function of the Scavenger Receptor Class A
T. Murakami, Y. Yamada,T. Doi.T. Hamakubo, and T. Kodama 108
Impairment of Reverse Cholesterol Transport System and Atherosclerosis
S. Yamashita, T. Maruyama, K. Hirano, N. Sakai, N. Nakajima,
and Y. Matsuzawa 115
ACAT Genes and Proteins in Humans
T.Y. Chang, C. Chang, O. Lee, and J. Cruz 124
Caveolin is Cholesterol Binding Protein
M. Murata 130
In Vivo Functions of SREBPs
H. Shimano and N. Yamada 137
Molecular Characterization of Arachidonate Preferring Acyl CoA
Synthetase, ACS4
Y. Y Cho, M. J. Kang, H. Minekura, S. Ogawa, T. Fujino, and T.T. Yamamoto 142
Molecular Characterization of Short Chain Acyl CoA Synthetases
T. Fujino, H. Sato, Y. Cho, and T.T. Yamamoto 144
Expression of the VLDL Receptor is Up Regulated by Cell Differentiation
in HL 60 Cells
S. Takahashi, M. Kohno, S. Kosaka, K. Masamura, J. Suzuki, K. Oida,
T. Yamamoto, and I. Miyamori 146
Transcriptional Regulation of the Genes for Human HMG CoA Synthase and
Squalene Synthase by SREBP and NF Y
J. Inoue and R. Sato 149
Expression of Acyl Coenzyme A: Cholesterol Acyltransferase 1 (ACAT 1) Protein
in Human Atherosclerotic Lesions and Cultured Monocytes Macrophages
A. Miyazaki, N. Sakashita, K.K. Maung, K. Takahashi, S. Horiuchi,
C.C.Y. Chang, and T.Y. Chang 152
XII
Relationship Between Postprandial Triglyceride Level and Intima Media Thickness
of Carotid Artery After Troglitazone Treatment in Type 2 Diabetes
H. Koshiyama, S. Tanaka, J. Minamikawa, and K. Nakao 154
A New Rabbit Strain with Heritable Hypercholesterolemia and Hypertriglyceridemia
S. Takasaki, C. Zhang, T. Ito, and H. Tomoike 157
Turnover of Glutathione and Ascorbic Acid is Suppressed in Hyperlipidemic Rabbits
K. Suzumura, E. Kasahara, K. C. Chien, and M. Inoue 160
Pravastatin, an HMG CoA Reductase Inhibitor, is Transported by Rat Organic
Anion Transporting Polypeptide, oatp2
T. Tokui, D. Nakai, R. Nakagomi, M. Kakyo, T. Nishio, T. Abe, H. Suzuki,
and Y. Sugiyama 163
Chapter 4: The Search for the Link Between Lipoprotein Metabolism
Disorder and Atherogenesis (I)
The Puzzling Ligands for Scavenger Receptors
D.Steinberg 169
Granulocyte Macrophage Colony Stimulating Factor is Involved in Murine
Macrophage Proliferation Induced by Oxidized Low Density Lipoprotein
T. Biwa, H. Hakamata, M. Sakai, A. Miyazaki, and S. Horiuchi 176
Mast Cells in Atherogenesis: A Model for Studying Proteolytic Modification of
Low and High Density Lipoproteins
P.T. Kovanen, M. Lee, L. Lindstedt, and K. Oorni 184
LOX 1, an Endothelial Receptor for Oxidized LDL — Implications for Induction of
Endothelium Dysfunction in the Pathogenesis of Vascular Diseases —
T. Sawamura, M. Kakutani, C. Mingyi, and T. Masaki 193
Inducible Expression of Lectin Like Oxidized Low Density Lipoprotein Receptor 1
in Vascular Endothelial Cells and Macrophages
N. Kume, T. Murase, H. Moriwaki, H. Kataoka, M. Minami, and T. Kita 199
Identification and Characterization of a PDZ Domain Containing Protein that
Interacts with the HDL Receptor SR BI
M. Ikemoto, D. Feng, H. Arai, M. Tsujimoto, and K. Inoue 207
Structure and Function of Human SREC (Scavenger Receptor Expressed by
Endothelial Cells), A Novel Receptor for Modified LDL
H. Adachi, M. Tsujimoto, H. Arai, and K. Inoue 210
The Role of CD36 in Atherogenesis as a Receptor for OxLDL
S. Nozaki, S. Yamashita, and Y. Matsuzawa 213
Apoptosis in Atherosclerosis: Induction of Apoptosis by Oxidized Low Density
Lipoprotein and Oxysterols
K. Harada, Z. Chen, N. Yamada, and S. Ishibashi 219
XIII
Combination Treatment with an Insulin Action Enhancer and an Inhibitor
of HMG CoA Reductase Shows a Synergistic Effect on Atherosclerosis
of WHHL Rabbits
M. Shiomi, T. Ito, T. Tsukada, Y. Tsujita, and H. Horikoshi 224
Reduced Secretion of Tumor Necrosis Factor a and Interleukin 1 (J from Monocy te
Derived Macrophages of CD36 Deficient Subjects in Response to Oxidized LDL
M. Janabi, S. Yamashita, K. Hirano, K. Matsumoto, S. Nozaki,
and Y. Matsuzawa 227
CD36 Expression in Human Monocytic Leukemia Cell Lines: THP 1 and THP 1
Subtype, Show Different Expressions of Type I and Type II Scavenger Receptors
R. Sugano, M. Harada Shiba, N. Nishimura, Y. Miyake, J. An, D.X. Hui,
T. Yamamura, and A. Yamamoto 230
Chapter 5: The Search for the Link Between Lipoprotein Metabolism
Disorder and Atherogenesis (II)
Alteration of Smooth Muscle Cell Phenotype in Diabetic Vascular Wall: From the
Molecular Point of View
Y. Saito, K. Yokote, K. Tamura, M. Takemoto, T. Matsumoto, H. Ueno,
and S. Mori 235
The Vascular Nitric Oxide/Superoxide System and Atherosclerosis
M. Yokoyama, N. Inoue, K. Hirata, and S. Kawashima 243
Antagonistic Monoclonal Antibody Against Receptor Tyrosine Kinases: A Novel
Strategy to Study the Role of Monocyte/Macrophage in Atherogenesis In Vivo
M. Yokode, T. Murayama, H. Kataoka, T. Imabayashi, H. Yoshida, H. Sano,
S. Nishikawa, S. Nishikawa, and T. Kita 246
Rac 1 and CDC42Hs Play a Critical Role in MCP 1 Induced Chemotaxis
H. Arai and I.F. Charo 254
Stimulation of Mitogen Activated Kinases by Lysophosphatidylcholine in Bovine
Aortic Endothelial Cells
H. Ozaki, K. Ishii, H. Arai, N. Kume, andT. Kita 257
Ca2+ Dependent Activation of the 33 kDa Thrombin Receptor Associated Kinase
in Human Platelets
M. Ido, T. Hayashi, and K. Suzuki 260
Lysophosphatidylcholine Generates Superoxide Anios Through Activation of
Phosphatidylinositol 3 Kinase in Human Neutrophils
H. Nishioka, H. Horiuchi, H. Arai, andT. Kita 263
PDGF Enhanced 7 Ketocholesterol Induced Apoptosis of Vascular Smooth Muscle
Cell, Accompaning with c myc Expression
Y. Miyashita, T. Murano, H. Watanabe, Y. Itoh, M. Totsuka, and K. Shirai 266
XIV
Adventitia Derived Macrophages Contribute to the Formation of Coronary
Arteriosclerotic Lesions in Pigs In Vivo — Potentiating Effect of Oxidative Stress —
K. Miyata, H. Shimokawa, and A. Takeshita 269
Expression of CD36 in Cultured Human Aortic Smooth Muscle Cells (HASMCs)
K. Matsumoto, K. Hirano, S. Nozaki, M. Nishida, T. Ohya, M.J. Yakub,
T. Funahashi, S. Yamashita, and Y. Matsuzawa 272
Induction of Macrophage VEGF in Response to Oxidized LDL and VEGF
Accumulation in Human Atherosclerotic Lesion
M. Kuzuya, M.A. Ramos, S. Kanda, and A. Iguchi 275
F 1394, an ACAT Inhibitor, Inhibits Neointimal Thickening and Macrophage
Accumulation After Balloon Injury in the Cholesterol Fed Rabbit
K. Aragane, K. Kojima, T. Kitamine, K. Fujinami, H. Kozono, K. Kano,
T. Chiwata, J. Kusunoki, and Y. Sekine 278
Key Word Index 281
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discipline | Biologie Medizin |
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indexdate | 2024-07-09T18:46:04Z |
institution | BVB |
isbn | 443170261X |
language | English |
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physical | XVIII, 283 S. Ill., graph. Darst. : 24 cm |
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publisher | Springer |
record_format | marc |
spelling | Lipoprotein metabolism and atherogenesis T. Kita ; M. Yokode (ed.) Tokyo ; Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ; Springer 2000 XVIII, 283 S. Ill., graph. Darst. : 24 cm txt rdacontent n rdamedia nc rdacarrier Literaturangaben Adipose Tissue metabolism Congresses Adipose tissues Metabolism Congresses Arteriosclerosis metabolism Congresses Atherosclerosis Etiology Congresses Lipoproteins Metabolism Congresses Lipoproteins metabolism Congresses Lipidstoffwechsel (DE-588)4035875-6 gnd rswk-swf Atherogenese (DE-588)4195269-8 gnd rswk-swf Lipidstoffwechselstörung (DE-588)4035876-8 gnd rswk-swf Arteriosklerose (DE-588)4068866-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1998 Kioto gnd-content Lipidstoffwechsel (DE-588)4035875-6 s Atherogenese (DE-588)4195269-8 s DE-604 Lipidstoffwechselstörung (DE-588)4035876-8 s Arteriosklerose (DE-588)4068866-5 s Kita, Toru Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009177896&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Lipoprotein metabolism and atherogenesis Adipose Tissue metabolism Congresses Adipose tissues Metabolism Congresses Arteriosclerosis metabolism Congresses Atherosclerosis Etiology Congresses Lipoproteins Metabolism Congresses Lipoproteins metabolism Congresses Lipidstoffwechsel (DE-588)4035875-6 gnd Atherogenese (DE-588)4195269-8 gnd Lipidstoffwechselstörung (DE-588)4035876-8 gnd Arteriosklerose (DE-588)4068866-5 gnd |
subject_GND | (DE-588)4035875-6 (DE-588)4195269-8 (DE-588)4035876-8 (DE-588)4068866-5 (DE-588)1071861417 |
title | Lipoprotein metabolism and atherogenesis |
title_auth | Lipoprotein metabolism and atherogenesis |
title_exact_search | Lipoprotein metabolism and atherogenesis |
title_full | Lipoprotein metabolism and atherogenesis T. Kita ; M. Yokode (ed.) |
title_fullStr | Lipoprotein metabolism and atherogenesis T. Kita ; M. Yokode (ed.) |
title_full_unstemmed | Lipoprotein metabolism and atherogenesis T. Kita ; M. Yokode (ed.) |
title_short | Lipoprotein metabolism and atherogenesis |
title_sort | lipoprotein metabolism and atherogenesis |
topic | Adipose Tissue metabolism Congresses Adipose tissues Metabolism Congresses Arteriosclerosis metabolism Congresses Atherosclerosis Etiology Congresses Lipoproteins Metabolism Congresses Lipoproteins metabolism Congresses Lipidstoffwechsel (DE-588)4035875-6 gnd Atherogenese (DE-588)4195269-8 gnd Lipidstoffwechselstörung (DE-588)4035876-8 gnd Arteriosklerose (DE-588)4068866-5 gnd |
topic_facet | Adipose Tissue metabolism Congresses Adipose tissues Metabolism Congresses Arteriosclerosis metabolism Congresses Atherosclerosis Etiology Congresses Lipoproteins Metabolism Congresses Lipoproteins metabolism Congresses Lipidstoffwechsel Atherogenese Lipidstoffwechselstörung Arteriosklerose Konferenzschrift 1998 Kioto |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009177896&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT kitatoru lipoproteinmetabolismandatherogenesis |