The centrosome in cell replication and early development:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego [u.a.]
Acad. Press
2000
|
| Schriftenreihe: | Current topics in developmental biology
49 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVIII, 489 S. Ill., graph. Darst. |
| ISBN: | 012153149X |
Internformat
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| 650 | 4 | |a Centrosomes | |
| 650 | 4 | |a Cell Cycle |x physiology | |
| 650 | 4 | |a Cell Division |x physiology | |
| 650 | 4 | |a Cell division | |
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Datensatz im Suchindex
| _version_ | 1804128225186545665 |
|---|---|
| adam_text | Contents
Contributors xv
Preface xix
1 The Centrosome and Parthenogenesis
Thomas Kuntziger and Michel Bornens
I. Introduction 1
II. Toward a Functional Description of the Centrosome 2
III. The Centrosome Organelle versus Self Assembled Centers 12
IV. Centrosome Reproduction and the Parthenogenetic Activity of
the Centrosome 13
V. Conclusion 18
References 19
2 y Tubulin
Berl R. Oakley
I. Centrosomes and Microtubule Nucleation 27
II y Tubulin and the Tubulin Superfamily of Proteins 30
III. Distribution of y Tubulin in Cells 33
IV. Studies of y Tubulin Function 39
V. y Tubulin and Microtubule Assembly: Current Knowledge and
Unanswered Questions 45
VI. Concluding Remarks 49
References 49
3 ¦y Tubulin Complexes and Their Role in Microtubule Nucleation
Ruwanthi N. Gunawardane, Sofia B. Lizarraga, Christiane Wiese, Andrew Wilde,
and Yixian Zheng
I. Introduction 55
II. Biochemical and Structural Studies of yTuRC and yTuSC 57
vii
viii Contents
III. Evidence That yTuRC Is the Major Microtubule Nucleator at
the Centrosome 64
IV. The Mechanism of Microtubule Nucleation 65
V. Concluding Remarks 69
References 70
4 y Tubulin of Budding Yeast
Jackie Vogel and Michael Snyder
I. Introduction 75
II. Tubulins of Yeast 80
III. Interactions between Tubulins 88
IV. The y Tubulin Complex in Yeast 91
V. Future Directions 95
References 97
5 The Spindle Pole Body of Saccharomyces cerevisiae: Architecture and
Assembly of the Core Components
Susan E. Francis and Trisha N. Davis
I. Introduction 105
II. SPB Duplication and Assembly of the Mitotic Spindle 106
III. Structure of the SPB 107
IV. SPB Core Components 109
V. Assembly of the Core SPB Components 122
VI. Transcriptional Regulation of Core SPB Components 123
VII. Homologs of Spindle Pole Components in
Other Organisms 124
VIII. Future Directions 125
References 128
6 The Microtubule Organizing Centers of Schizosaccharomyces pombe
lain M. Hagan and Janni Petersen
I. Introduction 133
II. Cytoplasmic Microtubule Organizing Centers 136
Contents ix
III. The Spindle Pole Body 138
IV. Molecular Characterization of SPB Components 149
V. Perspectives 153
References 154
7 Comparative Structural, Molecular, and Functional Aspects of the
Dictyostelium discoideum Centrosome
Ralph Graf, Nicole Brusis, Christine Daunderer, Ursula Euteneuer,
Andrea Hestermann, Manfred Schliwa, and Masahiro Ueda
I. Introduction 161
II. Comparative Morphology of the Dictyostelium Centrosome 163
III. Comparative Analysis of Dictyostelium Centrosome Duplication 167
IV. Comparative Molecular Biology of the Dictyostelium Centrosome 171
V. Conclusions 179
References 179
8 Are There Nucleic Acids in the Centrosome?
Wallace F. Marshall and Joel L. Rosenbaum
I. Introduction 187
II. Do Centrioles or Centrosomes Contain DNA? 188
III. Do Centrosomes Contain RNA? 197
IV. Conclusions 201
References 202
9 Basal Bodies and Centrioles: Their Function and Structure
Andrea M. Preble, Thomas M. Ciddings, Jr., and Susan K. Dutcher
I. Introduction to Centrioles and Basal Bodies 207
II. The Structure of Centrioles and Basal Bodies 212
III. The Function of Basal Bodies and Centrioles as Revealed by
Mutational Analysis 221
IV. Basal Body/Centriole Replication 226
References 228
x Contents
10 Centriole Duplication and Maturation in Animal Cells
B. M. H. Lange, A. J. Faragher, P. March, and K. Cull
I. Overview 235
II. Centriole Lineage Patterns 236
III. Structural Features of Centriole Maturation and Duplication 236
IV. Centriolar Duplication, Maturation, and the Cell Cycle 239
V. Centriolar Maturation and Centriolar Function 242
VI. Ciliogenesis and Cell Cycle 244
VII. Future Developments and Directions 245
References 245
11 Centrosome Replication in Somatic Cells: The Significance of the
G, Phase
Ron Balczon
I. Introduction 251
II. The Cell Cycle in Somatic Mammalian Cells 251
III. Electron Microscopic Descriptions of Centrosome Doubling, and the
Cellular Events of Centrosome Replication 252
IV. Spindle Pole Body Doubling in Yeast Cells 255
V. Events in Gi That Trigger Centrosome Replication in Somatic
Mammalian Cells 260
VI. Summary 263
References 264
12 The Coordination of Centrosome Reproduction with Nuclear Events
during the Cell Cycle
Greenfield Sluder and Edward H. Hinchcliffe
I. Introduction 267
II. The Events of Centrosome Reproduction 269
HI. Controls for Centrosome Reproduction 271
IV. Coordination of Centrosome Reproduction with Nuclear Events in the
Cell Cycle 276
References 286
Contents xi
13 Regulating Centrosomes by Protein Phosphorylation
Andrew M. Fry, Thibault Mayor, and Erich A. Nigg
I. Introduction 291
II. Protein Phosphorylation: A Major Theme in Cell Cycle Control 292
III. Centrosome and Spindle Pole Body Dynamics through the
Cell Cycle 294
IV. In Control of Centrosome Duplication 295
V. Regulating Microtubule Nucleation 298
VI. Establishing a Bipolar Mitotic Spindle 300
VII. Creating the Zygotic Centrosome 305
VIII. Loss of Phosphorylation Control: Cancer Implications 306
IX. Perspectives: Into the Next Millennium 308
References 309
14 The Role of the Centrosome in the Development of Malignant Tumors
Wilma L. tingle and Jeffrey L. Salisbury
I. Introduction 313
II. Centrosome Defects and Abnormal Mitoses in Cancer 316
III. Amplified Centrosomes and Aneuploidy 317
IV. Excess Pericentriolar Material Is Associated with High Frequency of
Abnormal Mitoses 319
V. Centrosome Associated Kinases and Cancer 320
VI. Tumor Suppressor Proteins and the Centrosome 321
VII. Maintenance of Cell and Tissue Polarity Minimizes Tumor Aggression in
Model Systems 324
VIII. Conclusions 325
References 326
15 The Centrosome Associated Aurora/lpl like Kinase Family
T. M. Coepfert and B. R. Brinkley
I. Introduction 331
II. The Aurora and Ipl like Family: Structure, Regulation,
and Substrates 333
III. Summary 339
References 340
xii Contents
16 Centrosome Reduction during Mammalian Spermiogenesis
C. Manandhar, C. Simerly, and C. Schatten
I. Introduction 343
II. Overview of Mammalian Spermiogenesis 345
HI. Stages of Centrosome Reduction during Spermiogenesis 347
IV. Conclusions 358
References 358
17 The Centrosome of the Early C. elegans Embryo: Inheritance, Assembly,
Replication, and Developmental Roles
Kevin F. O Connell
I. Why C. elegans? 365
II. Origin and Replication of the Zygotic Centrosomes 367
III. The Central Role of the Centrosome Pronucleus Complex in Specifying
AP Polarity 374
IV. Nuclear Positioning 378
V. Concluding Remarks 380
References 381
18 The Centrosome in Drosophila Oocyte Development
Timothy L. Megraw and Thomas C. Kaufman
I. Introduction 385
II. The Germarium: Centrosomes Are Anchored to Achieve Polarized
Cell Divisions 387
III. The Oocyte MTOC 391
IV. Meiosis 396
V. Summary 400
References 402
19 The Centrosome in Early Drosophila Embryogenesis
W. F. Rothwell and W. Sullivan
I. Introduction 410
II. Ultrastructure 412
Contents xiii
III. Composition 415
IV. Duplication and Separation 421
V. Fertilization and the First Mitotic Division 427
VI. Precortical Divisions 430
VII. Cortical Divisions 432
References 440
20 Centrosome Maturation
Robert E. Palazzo, Jacalyn M. Vogel, Bradley ). Schnackenberg, Dawn R. Hull,
and Xingyong Wu
I. Introduction 449
II. Centrosome Maturation 451
III. Centrosome Structure and Microtubule Nucleation Potential 453
IV. The Role of the Centriole 457
V. The Procentrosome 458
VI. Paternal versus Maternal Centrosomes 460
VII. Summary 462
References 463
Index 471
Contents of Previous Volumes 485
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| spelling | The centrosome in cell replication and early development ed. by Robert E. Palazzo ... San Diego [u.a.] Acad. Press 2000 XVIII, 489 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Current topics in developmental biology 49 Celdeling gtt Cellules - Division Centrosomen gtt Centrosomes Cell Cycle physiology Cell Division physiology Cell division Centrosome Zelle (DE-588)4067537-3 gnd rswk-swf Zellteilung (DE-588)4190668-8 gnd rswk-swf Centrosom (DE-588)4295334-0 gnd rswk-swf Entwicklung (DE-588)4113450-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Centrosom (DE-588)4295334-0 s Zellteilung (DE-588)4190668-8 s DE-604 Zelle (DE-588)4067537-3 s Entwicklung (DE-588)4113450-3 s Palazzo, Robert E. Sonstige oth Current topics in developmental biology 49 (DE-604)BV002685390 49 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009169160&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The centrosome in cell replication and early development Current topics in developmental biology Celdeling gtt Cellules - Division Centrosomen gtt Centrosomes Cell Cycle physiology Cell Division physiology Cell division Centrosome Zelle (DE-588)4067537-3 gnd Zellteilung (DE-588)4190668-8 gnd Centrosom (DE-588)4295334-0 gnd Entwicklung (DE-588)4113450-3 gnd |
| subject_GND | (DE-588)4067537-3 (DE-588)4190668-8 (DE-588)4295334-0 (DE-588)4113450-3 (DE-588)4143413-4 |
| title | The centrosome in cell replication and early development |
| title_auth | The centrosome in cell replication and early development |
| title_exact_search | The centrosome in cell replication and early development |
| title_full | The centrosome in cell replication and early development ed. by Robert E. Palazzo ... |
| title_fullStr | The centrosome in cell replication and early development ed. by Robert E. Palazzo ... |
| title_full_unstemmed | The centrosome in cell replication and early development ed. by Robert E. Palazzo ... |
| title_short | The centrosome in cell replication and early development |
| title_sort | the centrosome in cell replication and early development |
| topic | Celdeling gtt Cellules - Division Centrosomen gtt Centrosomes Cell Cycle physiology Cell Division physiology Cell division Centrosome Zelle (DE-588)4067537-3 gnd Zellteilung (DE-588)4190668-8 gnd Centrosom (DE-588)4295334-0 gnd Entwicklung (DE-588)4113450-3 gnd |
| topic_facet | Celdeling Cellules - Division Centrosomen Centrosomes Cell Cycle physiology Cell Division physiology Cell division Centrosome Zelle Zellteilung Centrosom Entwicklung Aufsatzsammlung |
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