Signaling through the cell matrix:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ; London
Springer
2000
|
| Schriftenreihe: | Progress in molecular and subcellular biology
25 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | X, 136 S. Ill., graph. Darst. : 24 cm |
| ISBN: | 3540672206 |
Internformat
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| 245 | 1 | 0 | |a Signaling through the cell matrix |c Alvaro Macieira-Coelho (ed.) |
| 264 | 1 | |a Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ; London |b Springer |c 2000 | |
| 300 | |a X, 136 S. |b Ill., graph. Darst. : 24 cm | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 1 | |a Progress in molecular and subcellular biology |v 25 | |
| 500 | |a Literaturangaben | ||
| 650 | 7 | |a Extracellulaire matrix |2 gtt | |
| 650 | 7 | |a Signalen |2 gtt | |
| 650 | 4 | |a Cell Adhesion | |
| 650 | 4 | |a Cell adhesion | |
| 650 | 4 | |a Cellular signal transduction | |
| 650 | 4 | |a Extracellular Matrix | |
| 650 | 4 | |a Extracellular matrix | |
| 650 | 4 | |a Signal Transduction | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-009017138 | ||
Datensatz im Suchindex
| _version_ | 1804127991362486272 |
|---|---|
| adam_text | Contents
Topological Constraints Carry Signaling from the Cell Matrix
to the Genome
A. Macieira Coelho
1 Variation in Cell Adhesion During Proliferation of
Normal Cells 1
1.1 Coupling Between Changes in Cell Adhesion and Proliferation
of Normal Cells 4
2 Coupling Between Changes in Cell Adhesion and
Proliferation of Transformed Cells 7
3 Mechanisms of Cell Adhesion Mediated Changes in the Cell
Phenotype 9
3.1 Modulation of Cell Proliferation 9
3.2 Modulation of Malignancy 11
3.3 Modulation of Cell Differentiation 12
4 Conclusions 14
References 16
The Transmission of Contractility Through Cell Adhesion
K. Imanaka Yoshida
1 Introduction 21
2 Generation of Contractility 21
2.1 Stress Fibers 21
2.2 Formation of Stress Fibers and Focal Adhesions 22
3 Molecular Mechanism of Force Transmission 22
3.1 Focal Adhesions 22
3.2 Mechanism of Force Transmission 23
3.3 Molecules Mediating Force Transmission 23
4 Regulation of Contractility Transmission 24
4.1 Regulation of Contractile Force 24
4.1.1 The Regulatory Mechanism of RhoA 24
4.1.2 Involvement of Microtubules 24
4.2 Regulation of Stability of Focal Adhesions 25
5 Interaction Between Contraction Force and ECM 25
6 Myofibroblasts and Wound Healing 26
7 Muscle 26
I
VIII Contents
7.1 Myotendinous Junctions 27
7.2 Costameres 27
7.2.1 Contraction Force Transmission at Costameres 27
7.2.2 Potential Involvement of Dystrophin 29
7.2.3 Significance of Costameres in Heart Function 29
8 Conclusion 29
References 30
Role of Focal Adhesion Kinase in Signaling by the Extracellular Matrix
Ji He Zhao and Jun Lin Guan
1 Introduction 37
2 FAK Activation by Integrin 39
2.1 FAK Interaction with Integrin 39
2.2 FAK Interaction with Cytoskeletal Proteins Talin, Paxillin,
and Tensin 39
3 FAK Downstream Pathways 40
3.1 FAK Interaction with Src 41
3.2 FAK Interaction with PI 3 Kinase 42
3.3 FAK Interaction with pl30cas 43
4 Biological Functions of FAK in Signaling by ECM 44
4.1 Cell Adhesion and Spreading 44
4.2 Cell Migration 46
4.3 Cell Survival and Apoptosis 47
4.4 Cell Cycle Progression and Proliferation 47
References 49
Interaction Between Cells and Extracellular Matrix:
Signaling by Integrins and the Elastin Laminin Receptor
J. Labat Robert and L. Robert
1 Introduction 57
2 Cell Matrix Interactions Mediated by Integrins 58
2.1 Signaling by Integrins 58
2.2 Evolution of Integrin Signaling with Aging 60
3 Cell Matrix Interactions Mediated by the Elastin Laminin
Receptor 61
3.1 Signaling by the Elastin Laminin Receptor 61
3.2 Effect of Age on the Elastin Laminin Receptor 65
3.3 Experiments on Lymphocytes 66
4 Discussion and Conclusions 68
References 68
Contents IX
Regulation of Gene Expression by Changes in Cell Adhesion
T. Kuzumaki
1 Introduction 71
2 Regulation of Cell Proliferation by Cell Adhesion 72
2.1 Regulation of the G! Phase 73
2.2 Molecular Basis for Regulation of the G,/S Transition 74
2.3 Regulation of Cycling A Gene Expression 77
3 Regulation of Cell Differentiation by Cell Adhesion 79
3.1 Differentiation of Hepatocytes and Regulation
of Albumin Gene Expression 80
3.2 Differentiation of Mammary Epithelial Cells and Regulation
of p Casein Gene Expression 82
4 Conclusion 83
References 84
Expression of Liver Specific Genes in Hepatocytes
Cultured in Collagen Gel Matrix
M.J. Gomez Lechon, R. Jover, T. Donato, X. Ponsoda, and J.V. Castell
1 Introduction 89
2 Culture of Hepatocytes in Collagen Gel 92
3 Hepatic Specific Functions of Hepatocytes
in Collagen Cultures 92
4 Biotransformation Capability: Basal and Induced Levels of
Drug Metabolizing Enzymes 93
5 Expression of Hepatic Transcription Factors 97
6 Concluding Remarks 99
References 99
Collagen Type I: A Substrate and a Signal for Invasion
L. Van Hoorde, E. Van Aken, and M. Mareel
1 Introduction 105
2 Invasion into Matrices 107
2.1 The Structure of Collagen Type I 108
2.2 Technical Aspects: Different Collagen Type I
Invasion Assays 110
2.3 Substrate Dependent Differences in Invasion 114
3 Effects of Collagen on the Invasive Behavior of Cells 117
3.1 Collagen Conformation 117
3.2 Organization of the Invade/Collagen Microecosystem 118
3.3 Invasion of Cells Without External Stimuli Other Than
Collagen Type I 119
3.4 Invasion, Angiogenesis, and Morphogenesis Assisted
by Helper Cells 120
3.5 Invasion Stimulated by Extrinsic Factors 121
X Contents
4 A Scenario for the Molecular Cross Talk Between
Collagen and Cell 124
5 Conclusion 125
References 127
Subject Index 135
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| id | DE-604.BV013230430 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:42:08Z |
| institution | BVB |
| isbn | 3540672206 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009017138 |
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| physical | X, 136 S. Ill., graph. Darst. : 24 cm |
| publishDate | 2000 |
| publishDateSearch | 2000 |
| publishDateSort | 2000 |
| publisher | Springer |
| record_format | marc |
| series | Progress in molecular and subcellular biology |
| series2 | Progress in molecular and subcellular biology |
| spelling | Signaling through the cell matrix Alvaro Macieira-Coelho (ed.) Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ; London Springer 2000 X, 136 S. Ill., graph. Darst. : 24 cm txt rdacontent n rdamedia nc rdacarrier Progress in molecular and subcellular biology 25 Literaturangaben Extracellulaire matrix gtt Signalen gtt Cell Adhesion Cell adhesion Cellular signal transduction Extracellular Matrix Extracellular matrix Signal Transduction Biosignalverarbeitung (DE-588)4006899-7 gnd rswk-swf Grundsubstanz (DE-588)4224942-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Grundsubstanz (DE-588)4224942-9 s Biosignalverarbeitung (DE-588)4006899-7 s DE-604 Macieira-Coelho, Alvaro 1932- Sonstige (DE-588)120401126 oth Progress in molecular and subcellular biology 25 (DE-604)BV002534931 25 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009017138&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Signaling through the cell matrix Progress in molecular and subcellular biology Extracellulaire matrix gtt Signalen gtt Cell Adhesion Cell adhesion Cellular signal transduction Extracellular Matrix Extracellular matrix Signal Transduction Biosignalverarbeitung (DE-588)4006899-7 gnd Grundsubstanz (DE-588)4224942-9 gnd |
| subject_GND | (DE-588)4006899-7 (DE-588)4224942-9 (DE-588)4143413-4 |
| title | Signaling through the cell matrix |
| title_auth | Signaling through the cell matrix |
| title_exact_search | Signaling through the cell matrix |
| title_full | Signaling through the cell matrix Alvaro Macieira-Coelho (ed.) |
| title_fullStr | Signaling through the cell matrix Alvaro Macieira-Coelho (ed.) |
| title_full_unstemmed | Signaling through the cell matrix Alvaro Macieira-Coelho (ed.) |
| title_short | Signaling through the cell matrix |
| title_sort | signaling through the cell matrix |
| topic | Extracellulaire matrix gtt Signalen gtt Cell Adhesion Cell adhesion Cellular signal transduction Extracellular Matrix Extracellular matrix Signal Transduction Biosignalverarbeitung (DE-588)4006899-7 gnd Grundsubstanz (DE-588)4224942-9 gnd |
| topic_facet | Extracellulaire matrix Signalen Cell Adhesion Cell adhesion Cellular signal transduction Extracellular Matrix Extracellular matrix Signal Transduction Biosignalverarbeitung Grundsubstanz Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009017138&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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