Amyloid and amyloidosis 1998: the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA
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Sprache: | English |
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New York [u.a.]
Parthenon Publ.
1999
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Beschreibung: | XXI, 585 S. Ill., graph. Darst. |
ISBN: | 1850700877 |
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Datensatz im Suchindex
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adam_text | CONTENTS
Preface xxi
SECTION 1 Fibril Formation
Amyloid 1998 2
A.S. Cohen
Serum amyloid P component. Structure, function and role in amyloidosis 6
M.B. Pepys
Protofilament structure and fibril assembly in TTR Met30 amyloid 11
H. Inouye, F.S. Domingues, A.M. Damas, M.J. Saraiva, E. Lundgren,
O. Sandgren and D.A. Kirschner
Direct evidence that the amino terminal portion of serum amyloid A (SAA) 14
is required for binding to HDL
B. Kluve Beckerman, J. Hardwick, N. Mercer and J.J. Liepnieks
Basic residues in the carboxy terminus of mouse apoSAA are involved in 17
heparin binding
J.B. Ancsin and R. Kisilevsky
Altering the aggregation pathway of amyloidogenic proteins by sulfated 20
and sulfonated glycosaminoglycan analogues
L.C. Serpell, X. Kong, W.A. Szrek, R. Kisilevsky and RE. Fraser
Analysis of autoaggregation and ligand binding sites of serum amyloid P 23
component by in vitro mutagenesis
D.R. Booth, J.R. Gallimore, W.L. Hutchinson, E. Hohenester, D. Thompson,
S. Wood and M.B. Pepys
Ultrastructural localization of serum amyloid P component and proteoglycan 26
in in vitro formed amyloid fibrils
E. Holm Nielsen, M. Nybo, B. Samuelsen andS. E. Svehag
Nature and specificity of amyloid fibril binding by serum amyloid P component 29
L.B. Lovat, E. Hohenester, P. Westermark, S.P. Wood and M.B. Pepys
Human serum amyloid P component in whole serum is pentameric and is not 32
complexed with other proteins
W.L. Hutchinson, E. Hohenester, S.J. Perkins, J. Herbert and M.B. Pepys
Comparison of recombinant X6 VL proteins chemical and thermal stability 35
correlates with fibrillogenic potential
J.S. Wall, M. Schell, C.L. Murphy and A. Solomon
Induction of (3 sheet in amyloidogenic proteins by spontaneous cyclization 38
of aspartate
J. Orpiszewski, N. Schormann andM.D. Benson
The crystal structure of amyloidogenic Leu55Pro transthyretin variant 41
indicates a possible pathway for protein aggregation into amyloid fibrils
M.P. Sebastido, M.J. Saraiva and A.M. Damas
Impact of cysteine (Cys) conjugation and pH on amyloid formation of wild type 44
and Met30 transthyretin (TTR)
Y. Ando, A. Gustavsson, O. Suhr, P. l. Ohlsson, H. Terazaki, K. Obayashi,
T. Yamashita, E. Ando, A. Negi, M. Ando and P. Westermark
Fibrillization in mouse senile amyloidosis is fibril conformation dependent 47
K. Higuchi, K. Kogishi, J. Wang, X. Chen, T. Chiba, T. Matsushita, Y. Hoshii,
H. Kawano, T. Ishihara, T. Yokota and M. Hosokawa
The role of phosphatidylinositol and inositol in amyloid fibril growth and arrest 50
J. McLaurin, T. Franklin, A. Chakrabartty and P.E. Fraser
Exogenous fibrils can induce amyloid formation in experimental murine 53
AA amyloidosis possible mechanism of amyloidogenesis
K. Landmark, G.T. Westermark, U. Engstrb m, A. Gustavsson,
P. Hultman and P. Westermark
AApoAII amyloid deposition is suppressed by adenovirus mediated overexpression 56
of type B apolipoprotein A II gene in the mice
T. Chiba, K. Kogishi, J. Wang, X. Chen, T. Matsushita, M. Hosokawa,
J. Miyazaki, 1. Saito, Y. Sasai and K. Higuchi
Novel composition of AL amyloid fibrils 59
A. Solomon, D.T. Weiss, C.L Murphy, R. Hrncic, J. Wall and M. Schell
Characterization of an atypical amyloid fibril protein (AL 366) from a patient 62
with multiple myeloma
/. Samdal, K. Sletten, K.E. Olsen and P. Westermark
Cloning, expression, purification and crystallization of variable domain of 65
lambda VI light chain
N. Schormann, J.J. Liepnieks and M.D. Benson
The crystal structure of [MET30]/[MET119] variant transthyretin the 68
stabilizing effects introduced by a benign mutation in an amyloidogenic variant
A.M. Damas, V. Lamzin, F. Domingues, M.P. Sebastido and M.J. Saraiva
Characterization of heparin binding to serum amyloid A 71
L.J. Lemieux and R. Kisilevsky
An in vitro binding assay of immobilized glycosaminoglycans and the terminal 74
27 amino acids of serum amyloid A
L.J. Lemieux, J. Gore, X. Kong, W. Szarek and R. Kisilevsky
Serum amyloid A: heparan sulfate interactions occur via specific 77
glycosaminoglycan motifs
J.B. Ancsin and R. Kisilevsky
A novel organization of in situ amyloid fibrils as established with high 80
resolution electronmicroscopy
5. Inoue, K. Ohashi, M. Saraiva and R. Kisilevsky
Structural analysis of AL amyloid fibrils 83
L.C. Serpell, T. Franklin, M.A. Benson and P.E. Fraser
SECTION 2 ALAmyloidosis
AL amyloidosis 88
G. Merlini
A prospective randomized trial of melphalan and prednisone versus vincristine, 96
carmustine, melphalan, cyclophosphamide, and prednisone in the treatment
of primary systemic amyloidosis
M.A. Gertz, M.Q. Lacy, J.A. Lust, P.R. Greipp, T.E. Witzig andR.A. Kyle
Dose intensive melphalan for AL amyloidosis: outcomes in 53 patients 99
R.L. Comenzo, E. Vosburgh, R. Falk, C. Fisher, K. Finn, L.M. Dember,
J. Berk, G. Akpek, V. Sanchorawala and M. Skinner
High dose melphalan and stem cell rescue for AL amyloidosis 102
J.D. Gillmore, J.F. Apperley, C. Craddock, S. Madhoo, M.B. Pepys
and P.N. Hawkins
Prognostic factors for survival and response after high dose therapy and 105
autologous stem cell transplantation (ASCT) in systemic AL amyloidosis:
a report on 21 patients
P. Moreau, V. Leblond, P. Bourquelot, T. Facon, A. Huynh, D. Caillot,
O. Hermine, M. Anal, M. Hamidou, G. Nedellec, A. Ferrant, B. Audhuy,
R. Bataille, N. Milpied and J. L. Harousseau
Treatment of AL amyloidosis with 4 iodo 4 deoxydoxorubicin 108
G. Merlini, M.J. Lechuga, E. Anesi, P. Garini, V. Perfetti, L. Obici, E. Ascari,
V. Bellotti, G. Capri and L Gianni
The effect of cardiac involvement on the outcome of intravenous melphalan 111
therapy and autologous stem cell rescue for AL amyloidosis
R.H. Falk, J. Reisinger, S.W. Dubrey, LA. Mendes, V. Sanchorawala,
D. Ekery, R. Comenzo, E. Vosburgh and M. Skinner
The clonal history of AL amyloidosis as revealed by analysis of light chain 115
variable region nucleotide sequences
V. Perfetti, P. Ubbiali, M. Colli Vignarelli, L. Obici, S. Casarini, E. Ascari,
E. Arbustini and G. Merlini
Bone marrow plasma cell light chain kTK ratio values have prognostic 118
relevance in AL amyloidosis
V. Perfetti, M. Colli Vignarelli, E. Anesi, P. Garini, S. Quaglini, P. Ubbiali,
E. Ascari and G. Merlini
Clonal cells circulate in the peripheral blood of virtually all patients with AL 121
amyloidosis
V. Perfetti, P. Ubbiali, M. Colli Vignarelli, L. Obici, M. Magni, P. Matteucci,
A.M. Gianni and G. Merlini
Immunoglobulin gene rearrangement in AL amyloidosis 124
A. Abusedra, T. Vulliamy, J.D. Gilmore, A. Bybee, P.N. Hawkins, M. Lqffan
and J.F. Apperley
Amyloiduria and renal A?i amyloid cast formation in a patient (ZIM) with 127
systemic AX amyloidosis. Induction of renal amyloid casts in mice by the
BJP (ZIM)
R.P. Linke, E. Kaiserling andJ. Saal
Elements in the amyloidogenic transformation of proteins 130
R.P. Linke
A descriptive study of chromosomal abnormalities in systemic amyloidosis and 133
correlation with biologic/prognostic variables
R. Fonseca, G.J.Ahmann, SM. Jalal, G.W. Dewald, M.A. GertzandP.R. Greipp
Imaging of amyloid deposits with 99mTc aprotinin: experience in the AL 136
and ATTR type
C. Aprile, R. Saponaro, G. Cannizzaro, F. Salvi, G. Calsamiglia, E. Anesi,
P. Garini and G. Merlini
Scintigraphic imaging and turnover studies with I serum amyloid P component 139
(SAP) in systemic amyloidosis
P.N. Hawkins, C. Aprile, G. Capri, L Vigano, E. Munzone, L. Gianni,
M.B. Pepys and G. Merlini
AL amyloidosis: clinical and therapeutic aspects 142
G. Merlini, E. Anesi, G. Banfi, A. Baraldi, F. Bergesio, T. Bertani, G. Cavallero,
N. Conte, M. Cossu, M. De Luca, M. Di Girolamo, R. Epis, R. Faedda, V. Fregoni,
G. Frigerio, A. Frosi, L Furci, P. Garini, D. Girelli, C. Grassi, S. Iannaccone,
E. Imbasciati, C. Loni, M. Manganaro, C. Manno, R. Marceno, V. Marenzi,
M. Marcatti, G. Marinone, F. Marzani, P. Melis, A. Miliani, M. Montanaro,
P. Musto, G. Palladini, E. Parisio, F. Pecchini, V. Perfetti, F. Pintus, C. Pozzi,
S. Quaglini, M. Quarenghi, F.P. Schena, A. Tocci, L. Uziel and E. Ascari
Alteration of thrombin inactivation by antithrombin III may contribute to 145
abnormal hemostasis in AL amyloidosis
G. Gamba, N. Montani, E. Anesi, I. Zorzoli, F. Lorenzutti and G. Merlini
Serum amyloid P component scintigraphy in AL amyloidosis 148
J.D. Gillmore, M.R. Persey, L.B. Lovat, S. Madhoo, M.B. Pepys
and P.N. Hawkins
Long term survival (10 years or more) in 30 patients with primary (AL) 151
amyloidosis
R.A. Kyle, M.A. Gertz, PR. Greipp, T.E. Witzig, J.A. Lust, M.Q. Lacy
and T.M. Therneau
Prognostic value of echo derived diagnosis of cardiac involvement in 154
primary amyloidosis
F. Recusani, L. Bucci, S. Ghio, S. De Feo, S. Quaglini, E. Anesi, P. Garini
and G. Merlini
The use of subcutaneous fat tissue for amyloid typing by Elisa 157
K.E. Olsen, K. Sletten and P. Westermark
Congo red overlay immunohistochemistry aids classification of amyloid deposits 160
G.A. Tennent, K.D. Cqfferty, M.B. Pepys and P.N. Hawkins
Characterization of three human immunoglobulin K amyloidogenic light chains 163
of different structural features
K.G. Mawuenyega, Y. Hara, M.A. Alim, K. Takeda, G. Sadik, F. Yamagata,
M. Taoka, H. Kaji, T. Isobe and T. Shinoda
Dissolution of human amyloid extract in the mouse 166
R. Hrncic, J.S. Wall, C.L. Murphy and A. Solomon
Morbidity associated with high dose therapy in primary amyloidosis 169
M.A. Kazmi and S.A. Schey
Phase II trial of high dose dexamethasone for previously treated primary systemic 172
amyloidosis
M.A. Gertz, M.Q. Lacy, J.A. Lust, PR. Greipp, T.E. Witzig andR.A. Kyle
High dose melphalan with CD34+ blood stem cell transplantation in patients 175
with AL amyloidosis: a feasible approach
G. Akpek, E. Vosburgh, D. Michelle, M. LaBlanc, C. Fisher, Y. Zhang,
J. Wally, G. Kica, M. Skinner, R. Falk, L.M. Dember, K. Finn, V. Sanchorawala
and R.L Comenzo
Immunoglobulin (Ig) light chain variable region gene usage and somatic 178
hypermutation in AL amyloidosis
R.L. Comenzo, G. Kica, Y. Zhang, L. Connors, J. Wally and M. Skinner
Improvement in AL amyloidosis associated renal disease following treatment 181
with intravenous melphalan and peripheral stem cell rescue
L.M. Dember, R.L. Comenzo, E. Vosburgh, R.H. Falk, V. Sanchorawala,
J. Berk, K. Finn, C. Fisher, G. Akpek and M. Skinner
Four year cumulative experience with dose intensive melphalan and peripheral 184
stem cell rescue in AL amyloidosis
E. Vosburgh, R.L. Comenzo, R. Falk, L. Dember, V. Sanchorawala, K. Finn
and M. Skinner
Myeloproliferative disorder like syndrome associated with AL amyloidosis 187
V. Sanchorawala, R.L. Comenzo, E. Vosburgh and M. Skinner
Infectious complications in patients with AL amyloidosis undergoing autologous 190
blood stem cell transplantation
V. Sanchorawala, E. Vosburgh, C. Fisher, M. Skinner and R.L. Comenzo
Biophysical studies of amyloidogenic and non amyloidogenic kappa I 193
immunoglobulin light chains
Z. Khan, L.H. Connors, M. Skinner and M.T. Walsh
Pronase pretreatment is useful for immunohistochemical differentiating 196
amyloidosis, light chain deposits disease and non amyloid fibrillar nephropathy
U. Donini and R.P. Linke
Liver transplantation in a patient with primary AL kappa amyloidosis 199
a case report
G. Nowak, P. Westermark, A. Wernerson, G. Herlenius, K. Sletten
and B. G. Ericzon
SECTION 3 Familial Amyloidosis
Current trends and perspectives in research on TTR related amyloidoses 204
M.J.M. Saraiva
Anticipation of age at onset in Portuguese patients with familial amyloid 209
polyneuropathy type I (FAP Met30)
A. Sousa, T. Coelho, L. Labato and J. Sequeiros
Transthyretin mutant exert cytotoxicity during amyloid formation 212
K. Andersson, A. Olofsson and E. Lundgren
Transcription studies of the transthyretin gene in foetal and adult tissues and 215
in three livers from transplanted patients affected with familial amyloidotic
polyneuropathy (Met30 and Pro36 mutations)
A. Ferlini, M. D Alessandro and E Salvi
Characterization of receptor mediated internalization of transthyretin 218
M. Sousa and M.J. Saraiva
Detection of transthyretin variants using immunoprecipitation and bioreactive 221
MALDI (Matrix Assisted Laser Desorption Ionization) probes
R. Theberge, M. Skinner, L. Connors and C.E. Costello
Gender dependent amyloid deposition in aging male mice transgenic for 224
human transthyretin
M. H. Teng, J. Y. Yin, R. Vidal, J. Ghiso, C. Tagoe, A. Kumar, G. Gallo
andJ. Buxbaum
The origin of the transthyretin ile 122 allele: haplotype analysis and population 227
studies
D.R. Jacobson, J. Schneider, M. Sobel, J. Yang, S. Malendowicz, J. Sobol,
P. Tufau and J.N. Buxbaum
Familial amyloidosis: variations on a theme by Andrade 230
M.D. Benson
Hereditary amyloid cardiomyopathy caused by a variant apolipoprotein Al 235
L. HamidiAsl, J.J. Liepnieks, K. HamidiAsl, T. Uemichi, G. Moulin,
E. Desjoyaux, R. Loire, M. Delpech, G. Grateau andM.D. Benson
Orthotopic liver transplantation for familial amyloid polyneuropathy: 238
the UK experience
A.J. Stangou, N.D. Heaton, M. Rela, D. Jewitt, C.J. Mathias, J. O Grady,
R.S. Williams, M.B. Pepys and P.N. Hawkins
Immunoelectron microscopy reveal differences between amyloid fibrils from the 241
vitreous of FAP patients with the TTR Met 30 and TTR Cys 114 mutations
A. Gustavsson, Y. Ando, O. Sandgren, E. Ando and P. Westermark
Superficial siderosis of the central nervous system in transthyretin related 244
hereditary amyloidosis
F. Salvi, M. Mascalchi, A. Ferlini, R. Plasmati and C.A. Tassinari
CyslO residue may be a key factor for Met30 TTR amyloidogenesis in 246
type I familial amyloidotic polyneuropathy
Y. Takaoka, M. Ohta, K. Miyakawa, H. Shimada, O. Nakamura, M. Suzuki,
K. Takahashi, K. Yamamura and Y. Sakaki
Macroscopic and microscopic manifestation of the gastrointestinal tract in familial 249
amyloidotic polyneuropathy (FAP Met30)
H. Terazaki, Y. Ando, S. Yoshimatsu, N. Sakashita, S. Tada, T. Yamashita,
M. Suga, M. Uchino and M. Ando
Heterogeneity of amyloid in transthyretin related amyloidosis 252
P. I. Ohlsson, Y. Ando and O.B. Suhr
A transgenic mouse bearing an amyloidogenic transthyretin allele 255
S. Zeldenrust and M.D. Benson
Dual expression of normal TTR and Met 30 TTR using baculovirus system 258
M. Nakamura, Y. Ando, B. Kluve Beckerman, K. Hamidi Asl, J.J. Liepnieks
and M.D. Benson
Central nervous system involvement of transthyretin amyloidosis 261
T. Uemichi, T. Azuma, A.H. Koeppen, S. Haeno, M. Funauchi, T. Matsubara,
T. Suzuki and M.D. Benson
Down regulation of transthyretin (TTR) (Met30) by replacement of normal protein 264
T. Yamashita, Y. Ando, M. Nakamura, M. Hashimoto, Y. Uemura,
K. Obayashi, H. Terazaki, M. Suga, M. Uchino and M. Ando
Transthyretin tyrll4cys provides a connection between dissociation of the 267
tetramer and exposure of the C loop D strand
A. Olofsson, C. Thylen, Y. Ando and E. Lundgren
Epidemiology of renal disease in the main focus of familial amyloid 270
polyneuropathy type I in Portugal
L Lobato, S.M. Guimaraes, I. Beirao, M. Silva, T. Coelho, J. Barms,
S. Guimaraes, J. Sequeiros and A. Sousa
Intravenous iron and recombinant human erythropoietin in the treatment of 273
anemia in familial amyloid polyneuropathy
L. Lobato, I. Beirao, M. Santos, R. Azevedo, P. Ribeiro and S. Guimaraes
Familial amyloid polyneuropathy type I (FAP Met30) in Portugal: phenotype 276
variability and deviations from Mendelian inheritance
A. Sousa, T. Coelho, J. Barros, C. Ferreira, L. Lobato and J. Sequeiros
Identification of an epitope expressed on amyloidogenic mutants of transthyretin 279
G. Goldsteins, H. Persson, I. Dacklin, K. Andersson, A. Olofsson,
M.J. Saraiva and E. Lundgren
Antibody reactivity to amyloidogenic transthyretin variants in serum of patients 282
with familial amyloidotic polyneuropathy FAP but not in normal serum
suggests the circulation of modified TTR species
J.A. Palha, A. Olofsson, E. Lundgren and M.J. Saraiva
IDOX binding to transthyretin amyloid in tissue sections and in synthetic fibrils 285
J.A. Palha, D. Ballinari, N. Amboldi, G. Merlini and M.J.M. Saraiva
Biochemical characterization of transthyretin Cys 114 associated with familial 288
amyloidotic polyneuropathy
Y. Ando, M.R.E. Almeida, E. Ando, A. Negi, O. Suhr, H. Terazaki,
K. Obayashi, K. Tashima and M.J.M. Saraiva
Nutritional support in familial amyloidotic polyneuropathy type I patients 291
/. Fonseca, L. Lobato, 1. Beirao and S. Guimaraes
Contribution of sensory and autonomic tests to the early confirmation of the 294
onset of familial amyloid polyneuropathy
T. Coelho, P. Ribeiro, C. Ferreira and A. Sousa
Characterization of transthyretin variants by multidimensional liquid 297
chromatography coupled to electrospray ionization mass spectrometry
M. Kishikawa, T. Nakanishi, A. Miyazaki and A. Shimizu
Two novel mutations associated with transthyretin type amyloidosis (ATTR) 300
R. Theberge, L Connors, M. Skinner, J. Skare, R. Falk and C.E. Costello
Screening for plasma transthyretins using isoelectric focusing (IEF), a test 303
for familial transthyretin amyloidosis (ATTR)
L.H. Connors, T. Ericsson, J. Skare, A. Amico, L.A. Jones, W.D. Lewis
and M. Skinner
Detection and quantification of variant proteins by electrospray ionization mass 306
spectrometry
A. Shimizu, T. Nakanishi, M. Kishikawa and A. Miyazaki
A new transthyretin variant (ILE 49) associated with familial amyloidotic 309
polyneuropathy
M. Nakamura, T. Yamashita, Y. Ando, K. HamidiAsl, K. Tashima,
P. I. Ohlsson, L. Wang and M.D. Benson
Functional characterization of synthetic transthyretin variants contribution 312
to the understanding of structure function relationships
M.R. Almeida, M. Pereira, A.M. Damas andM.J. Saraiva
Twelve abnormal transthyretins in systemic amyloidosis in Japan 315
M. Nakazato, M. Kishikawa and A. Shimizu
Renal amyloidosis with a frame shift mutation in flbrinogen A chain gene 318
producing a novel amyloid protein
L. Hamidi Asl, J.J. Liepnieks, T. Uemichi, J. M. Rebibou, E. Justrabo,
D. Droz, C. Mousson, J. M. Chalopin, M.D. Benson, M. Delpech
and G. Grateau
Characterization of the kidney amyloid subunit protein in a case of hereditary 321
renal amyloidosis associated with a GLU526VAL flbrinogen Aa chain mutation
J.J. Liepnieks, T. Uemichi and M.D Benson
APOA1 amyloidosis in the human intimal aorta; of wild type origin and in a 324
family with motor neuron disease and dementia
G. Mucchiano, M. Amarzguioui, H. Prydz, B. Hdggqvist, M. Vrethem,
G. Westermark, K. Sletten and P. Westermark
Transthyretin serine 44, a new variant associated with early onset neuropathic 327
and cardiac amyloidosis
M.Q. Lacy and D.R. Jacobson
Progressive cardiac amyloidosis following liver transplantation for familial 330
amyloid polyneuropathy
A.J. Stangou, D.R. Booth, N.D. Heaton, M. Rela, M. Monaghan,
P. Nihoyannopoulos, J. O Grady, R. Williams, M.B. Pepys and P.N. Hawkins
SAP scintigraphy in familial amyloid polyneuropathy: regression of visceral 333
amyloid following liver transplantation
P.N. Hawkins, A. Rydh, A. Danielsson, S. Cajander, S. O. Hietala,
K. Riklund Ahlstrom, M.B. Pepys and O. Suhr
Curative hepatorenal transplantation for systemic amyloidosis associated with 336
flbrinogen a chain Glu526Val in an English family
J.D. Gillmore, D.R. Booth, M. Rela, N.D. Heaton, R.S. Williams, P. Harrison,
M.B. Pepys and P.N. Hawkins
Vitreous amyloid in a patient with FAP TTR Met 30 after liver transplantation 339
M. Munar Ques, Salvd Ladaria, P. Mulet Perera, M. Sole and M.J. Saraiva
Familial amyloidotic polyneuropathy world transplant registry update 342
G. Herlenius, M. Larsson and B. G. Ericzon
Transthyretin variants in late onset cardiac amyloidosis: distinguishing 344
familial amyloid cardiomyopathy from senile cardiac amyloidosis
D.R. Jacobson, 1. Kane, M.A. Gertz, G. Gallo, T. Pan, P. Tufau
andJ.N. Buxbaum
Detection of transthyretin gene mutations in amyloid cardiomyopathy by 347
analysis of DNA extracted from formalin fixed and paraffin embedded tissue
M. Nakazato, Y. Date and S. Matsukura
SECTION 4 AA Amyloidosis
AA Amyloidosis 352
R. Kisilevsky
Amyloid deposition in cultures of murine peritoneal cells incubated with 357
recombinant serum amyloid A
B. Kluve Beckerman, J.J. Liepnieks, L. Wang and M.D. Benson
Effect of high level of expression of transgenic serum amyloid A protein on 360
high density lipoproteins
M.S. Kindy, M.C. de Beer, C. Gerardot, J. Yu and EC. de Beer
Is serum amyloid A (SAA) an autocrine inhibitor of lipid synthesis? Either SAA 363
or interleukins 1 and 6 together inhibits lipid synthesis in HepG2 hepatoma cells
L.S. Kim, B.M. Schreiber, K. MacCarthy, J. S. Liang, A. Patel and J.D. Sipe
Influence of serum amyloid A (SAA) on macrophage Acyl CoA:cholesterol 366
acyltransferase (ACAT) activity
S. Ely and R. Kisilevsky
SAA1 alleles as risk factors in AA amyloidosis 369
DR. Booth, S.E. Booth, J.D. Gillmore, P.N. Hawkins and M.B. Pepys
Splenic deposition of AA amyloid may be enhanced by Apo A in ellipsoids 372
T.N. Wien, T. Landsverk, A. Espenes, G. Gunnes, K. Nordstoga and G. Husby
Human serum amyloid Al allele frequencies and their relationship to the 375
development of reactive amyloidosis in American Caucasian and Japanese
populations
L Wang, B. Kluve Beckerman, K. Takasugi, Y. Okuda, T. Uemichi,
T. Yamada, M. Nakamura and M.D. Benson
Antigenic characterization of recombinant serum amyloid A fusion proteins 378
F. Noetzel, E. Haindl and R.P. Linke
SAA separated by two dimensional electrophoresis with immobilized pH 381
gradients (2 IPG): methodological, experimental and clinical studies
C. Foyn Bruun and G. Marhaug
Mechanism of serum amyloid A gene expression in acute and chronic 384
inflammatory conditions
B.K. Ray and A. Ray
Natural history of experimental murine AA amyloidosis 387
P.N. Hawkins, J. Herbert, A. McBride, W.L Hutchinson and M.B. Pepys
Two breeds of chicken with different susceptibility to an amyloidogenic strain 390
of Enterococcus faecalis appear to have identical SAAs
J.H. Ovelgonne, W.J.M. Landman, A.E.J.M. van den Bogaard,
P.C.J. Tooten, A.LJ. Gielkens, B.P. Peeters andE. Gruys
Offspring of amyloidotic mice have no increased susceptibility to develop 393
amyloidosis
S. Shtrasburg, M. Pras, N. Brezniak and A. Livneh
Expression of serum amyloid A in human tissues: possible implications for 396
AA amyloidosis
S. Urieli Shoval, P. Cohen and Y. Matzner
Liver amyloid in a kindred with familial recurrent fever is derived predominantly 399
from SAA2
J.J. Liepnieks, A.J. Reginato, H. Eid, D.L. Kastner, I. Ansentijevich,
B. Kluve Beckerman and M.D. Benson
Cumulative SAA production and outcome of A A amyloidosis 402
J.D. Gillmore, L.B. Lovat, M.R. Persey, S. Madhoo, JR. Gallimore,
M.B. Pepys and P.N. Hawkins
Clinicopathological correlation with systemic secondary (AA) amyloidosis 405
in rheumatoid arthritis
A. Apathy and M. Bely
Systemic secondary (AA) amyloidosis in rheumatoid arthritis 408
M. Bely and A. Apathy
Diagnosis of incipient AA amyloidosis in pediatric rheumatic diseases: 411
favorable clinical consequences as estimated from a retrospective study
H. Michels and R.P. Linke
Alpha 1 antiprotease alleles as risk factors in A A amyloidosis 414
D.R. Booth, S.E. Booth, J.D. Gillmore, P.N. Hawkins and MB. Pepys
Serum amyloid A gene polymorphism and AA amyloidosis 417
5. Baba, S. Miyamoto, M. Kawashima, H. Nakai. M. Goto, B.J. Morris.
T. Sawaguchi, X. Wang, S. Tsugane, H. Sugimura. H. Shirusawa and Y. Tsutsui
Serum amyloid A (SAA) and phagocytosis of bacteria by human blood 420
monocytes
R.P. Linke and V. Bock
Modified silk as an amyloid enhancing factor 423
R. Kisilevsky, L Lemieux and L. Boudreau
Diagnostic and prognostic study of secondary amyloidosis complicating 426
rheumatoid arthritis
Y. Okuda and K. Takasugi
Serum amyloid A (SAA) gene expression by human aortic smooth muscle cells 429
Y. Kumon, Y. Nakauchi, T. Suehiro, K. Hashimoto andJ.D. Sipe
Adenoviral expression of murine serum amyloid A proteins to study amyloid 432
fibrillogenesis
M.S. Kindy, J. Yu and EC. de Beer
Fibrillogenic potential of amino terminus isoforms of mouse apoSAA 435
D.A. Kirschner, R. Elliott Bryant, K.E. Szumowski, W.A. Gonnerman,
M.S. Kindy, J.D. Sipe and E.S. Cathcart
Is amyloid enhancing factor (AEF) activity present in granulocyte colony 438
stimulating factor (G CSF)?
T. Yokota, T. Ishihara, M. Takahashi, H. Kawano, Y. Hoshii, T. Gondo,
M. Setoguchi, T. Iwata, T.A. Miyamoto and F. Uchino
The ultrastructural development of in vitro formed Apl 42 fibrils 441
S. E. Svehag, M. Nybo and E. Holm Nielsen
Chronologic sequence of amyloid deposition in glomerular structure 444
J. Rahoi, G. Ferencz, P Kapp and M. Bely
SECTION 5 Alzheimer s and Prion Disease
Progressive cerebral accumulation of the amyloid (3 protein as the central 448
pathogenetic event in Alzheimer s disease
D.J. Selkoe, W. Xia, M. Podlisny, D. Hartley and D. Walsh
Aging of Ap In Vitro: morphological progression to fibrils 453
D.A. Kirschner, S.B. Malinchik and K.E. Szumowski
Serum amyloid A and (3 amyloid protein (A(J) in Alzheimer s disease brain 456
T. F. Chung, J.D. Sipe, A. McKee, R.E. Fine, B.M. Schreiber,
7. 5. Liang and R.J. Johnson
Human hereditary prion protein amyloidosis 459
B. Ghetti, G. Giaccone, P. Piccardo, S.R. Dlouhy, O. Bugiani
and F. Tagliavini
Prion protein heterogeneity in Gerstmann Straussler Scheinker disease P102L 464
P. Piccardo, S.R. Dlouhy, P.M.J. Lievens, O. Bugiani, F. Tagliavini
and B. Ghetti
Polypeptide chain folding in hamster scrapie prion 467
H. Inouye and D.A. Kirschner
Apolipoprotein E and antioxidants have different mechanisms of inhibiting 470
Alzheimer s p amyloid fibril formation in vitro
H. Naiki, K. Hasegawa, I. Yamaguchi, H. Nakamura, F. Gejyo and K. Nakakuki
Confocal observation and 3 D reconstruction of senile plaques in Alzheimer s 473
disease senile plaque morphology and relationship between senile plaques
and astrocytes
T. Gondo, S. Kato, S. Mitsuno, Y. Hoshii, H. Kawano, M. Setoguchi,
M. Takahashi, T. Iwata and T. Ishihara
Interaction of NACP/a synuclein with p/A4 and effect on the fibril formation 476
in vitro
K. Takeda, S. Hossain, G. Sadik, H. Kaji, K. Veda and T. Shinoda
C terminal heterogeneity of the amyloid p protein (AP) in hereditary cerebral 479
hemorrhage with amyloidosis (Dutch) (HCHWA D)
M.L.C. Maat Schieman, H. Yamaguchi, S.G. van Duinen, R. Natte
andR.A.C. Roos
SECTION 6 Other Forms of Amyloidosis
Localized forms of amyloidosis a diverse group of amyloid disorders of 484
increasing interest
P. Westermark, B. Hdggqvist, K.H. Johnson, Z. Ma, G. Mucchiano,
K. Sletten and G.T. Westermark
Danish type gelsolin related amyloidosis: Tyr 187 mutation is associated 489
with accelerated amyloid fibril formation and abnormal fragmentation of
mutant gelsolin
C.P.J. Maury, M. Liljestrom, G. Boysen, T. Tornroth, A. de la Chapelle
and E. L. Nurmiaho Lassila
Pathogenic and therapeutic considerations in dialysis amyloidosis 492
F. Gejyo
P2 microglobulin can be refolded into a native state from ex vivo amyloid fibrils 497
V. Bellotti, M. Stoppini, P. Mangione, M. Sunde, C. Robinson, L. Asti,
A. Collura, D. Brancaccio, G. Merlini and G. Ferri
Apolipoprotein E e 4 allele is a risk factor for the onset of carpal tunnel 500
syndrome associated with dialysis related amyloidosis
F. Gejyo, H. Naiki, Y. Imura, H. Kimura, K. Hasegawa, I. Yamaguchi,
R. Miyazaki and T. Yamada
Heart transplantation in primary systemic amyloidosis 503
C.G.A. McGregor, RJ. Rodeheffer, R.C. Daly, R.A. Kyle, M.A. Gertz,
B.S. Edwards, L.J. Olson, R.P. Frantz and J.A. Dearani
Beta2 microglobulin fragmentation in amyloid fibril proteins separated by 506
gelfiltration and isoelectric focusing
E. Haindl, F. Noetzel, F. Lottspeich, J. Floege and R.P Linke
Expression and structural characterization of a fragment of P2 microglobuIin 509
ubiquitous in dialysis related amyloid fibrils
P. Mangione, M. Stoppini, G. Bergamaschi, I. Zorzoli, D. Booth, A. Cobianchi,
A. Collura, G. Ferri and V. Bellotti
Scintigraphic detection of P2 microglobulin dialysis related amyloidosis by 512
means of 99m technetium labelled aprotinin
C. Aprile, G. Villa, R. Saponaro, V. Piaza, E. Anesi, G. Cannizzaro, L. Picardi
and G. Merlini
Amyloid detected in tissue surrounding the modules of specific modular 515
endoprosthesis
C. Frank, R. Ascherl and S. Kerschbaumer
Ocular AL amyloidosis 518
R. Hrncic, C.L Murphy, J.S. Wall, D.T. Weiss and A. Solomon
Local synthesis of amyloid fibril precursor in primary amyloidosis of the 521
urinary tract
K. Hamidi Asl, J.J. Liepnieks, M. Nakamura and M.D. Benson
Organ limited amyloidosis of the deferent ducts, seminal vesicles and 524
ejaculatory ducts
R. Koren, A. Livneh, S. Shtrasburg, B. Goldwasser, R. Linke and R. Gal
Genetic risk factors for cerebral amyloid angiopathy in the elderly 527
M. Yamada, Y. ltoh, N. Sodeyama, N. Suematsu, E. Otomo,
M. Matsushita and H. Mizusawa
Cytotoxicity of human islet amyloid polypeptide, IAPP, Amylin : studies on 530
clonal P cells and intact pancreatic islets
C.E. Higham, M.K. Badman, S.A. Lowndes, M.D. Lewis, J.F. Morris and A. Clark
Insulin and islet amyloid polypeptide (IAPP) Amylin form stable molecular 533
complexes which could modify amyloid fibril formation in type 2 diabetes
E.T.A.S. Jaikaran, C.V. Robinson, P. Tito, P.E. Fraser and A. Clark
Multihormone producing islet cell tumor of the pancreas associated with 536
somatostatin immunoreactive amyloid: immunohistochemical and
immunoelectron microscopic studies
M. Takahashi, Y. Hoshii, H. Kawano, M. Setoguchi, T. Gondo, T. Kamei,
T. Iwata and T. Ishihara
Islet amyloid formation from human islet amyloid polypeptide in transgenic 539
mouse isolated islets is independent of glucose concentrations
D.L.A. MacArthur, E.J.P. de Koning and A. Clark
Human pro islet amyloid polypeptide forms amyloid like fibrils in vitro and 542
could promote islet amyloidosis in diabetes
R.L Hull, E.T.A.S. Jaikaran, L.C. Serpell, P.E. Fraser, A. Clark and M. Landon
A comparison of amyloid deposition in human and transgenic mouse islets 545
of Langerhans transplanted into nude mice
G.T. Westermark, P. Westermark and A. Andersson
The influence of dietary fat on islet amyloid polypeptide secretion from beta cells 548
G.T. Westermark and P. Westermark
Enhanced in vitro production of amyloid like fibrils from mutant (S20G) 551
islet amyloid polypeptide
P. Westermark, Z. Ma, A. Gustavsson, G.T. Westermark, U. Engstrom,
S. Sakagashira, T. Sanke and K. Nanjo
Transthyretin mutations in patients with apparent senile cardiac amyloidosis 554
D.R. Booth, J.D. Gillmore, M.B. Pepys and P.N. Hawkins
Transthyretin ILE 122 in a series of black patients with amyloidosis 556
A. Berg, R.H. Falk, L.H. Connors, R. Theberge, J. Skare, A. Murakami
and M. Skinner
Case report of familial amyloid cardiomyopathy associated with homozygous 559
variant sequence transthyretin (isoleucine 122)
C.R. Garrett, L.A. Solberg and D.R. Jacobson
Amyloid protein in aortic media is partly characterized 562
B. Haggqvist, G. Mucchiano, K. Sletten, J. Ndslund and P. Westermark
Familial amyloidosis of the mutant gelsolin (ASN 187) type in an American of 565
Italian ancestry
J.C. Skare, M. Skinner, N. Venna, R.H. Falk andJ. Talamo
Molecular mechanism of abnormal processing of amyloidosis associated form 568
of secretory gelsolin
H. Kangas, T. Paunio and L. Peltonen
Particular role of neuronal cells in the pathogenesis of familial amyloidosis, 571
Finnish type
T. Paunio, H. Kangas, J. Mallet and L. Peltonen
Chronic arthritis and y heavy deposition chain disease: coincidence or 574
pathogenic link?
G. Husby, P. Brandtzaeg, M. Danevad, O.J. Mellbye, T. Stenstad
and K. Sletten
Novel type of K light chain and (X heavy chain deposition disease 577
C.P.J. Maury, A. Kontiola, H. Kangas, A. M. Teppo, T. Pettersson
and R. Suomalainen
Index 581
|
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dewey-search | 616.3/995 |
dewey-sort | 3616.3 3995 |
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discipline | Medizin |
format | Conference Proceeding Book |
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spellingShingle | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA Amyloid Congresses Amyloidosis Congresses Neurodegenerative Diseases Congresses Amyloidose (DE-588)4142314-8 gnd |
subject_GND | (DE-588)4142314-8 (DE-588)1071861417 |
title | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA |
title_auth | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA |
title_exact_search | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA |
title_full | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA ed. by Robert A. Kyle ... |
title_fullStr | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA ed. by Robert A. Kyle ... |
title_full_unstemmed | Amyloid and amyloidosis 1998 the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA ed. by Robert A. Kyle ... |
title_short | Amyloid and amyloidosis 1998 |
title_sort | amyloid and amyloidosis 1998 the proceedings of the viiith international symposium on amyloidosis august 7 11 rochester minnesota usa |
title_sub | the proceedings of the VIIIth International Symposium on Amyloidosis, August 7 - 11, Rochester, Minnesota, USA |
topic | Amyloid Congresses Amyloidosis Congresses Neurodegenerative Diseases Congresses Amyloidose (DE-588)4142314-8 gnd |
topic_facet | Amyloid Congresses Amyloidosis Congresses Neurodegenerative Diseases Congresses Amyloidose Konferenzschrift 1998 Rochester Minn. |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008853305&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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