Multimodality treatment of lung cancer:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Dekker
2000
|
| Schriftenreihe: | Lung biology in health and disease
140 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XX, 472 S. Ill., graph. Darst. |
| ISBN: | 0824702360 |
Internformat
MARC
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| 245 | 1 | 0 | |a Multimodality treatment of lung cancer |c ed. by Arthur T. Skarin |
| 264 | 1 | |a New York [u.a.] |b Dekker |c 2000 | |
| 300 | |a XX, 472 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Lung biology in health and disease |v 140 | |
| 650 | 4 | |a Carcinoma, Non-Small-Cell Lung |x therapy | |
| 650 | 4 | |a Carcinoma, Small Cell |x therapy | |
| 650 | 4 | |a Combined Modality Therapy | |
| 650 | 4 | |a Lung Neoplasms |x therapy | |
| 650 | 4 | |a Lungs |x Cancer |x Treatment | |
| 650 | 0 | 7 | |a Therapie |0 (DE-588)4059798-2 |2 gnd |9 rswk-swf |
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| 700 | 1 | |a Skarin, Arthur T. |e Sonstige |4 oth | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-008787225 | ||
Datensatz im Suchindex
| _version_ | 1804127596408995840 |
|---|---|
| adam_text | CONTENTS
Introduction Claude Lenfant ///
Preface r
Contributors , j
Part One INTRODUCTION
1. Molecular and Cellular Biological Abnormalities in Lung Cancer
and the Potential for Novel Therapeutics 3
Ravi Salgia and Arthur T. Skarin
I. Introduction 3
II. Molecular Biological Abnormalities in Lung Cancer 4
III. Cellular Biological Abnormalities in Lung Cancer 9
IV. Metastasis I I
V. Novel Therapeutics in Lung Cancer ] 4
VI. Conclusions 19
References 19
2. Chemoprevention of Lung Cancer 27
Fadlo R. Khuri, Lamxa R. Tannous Khuri, and Waun Ki Hong
I. Introduction 27
II. Lung Cancer and Smoking 27
III. Toward a Model of Preneoplastic Disease 31
IV. Future Directions 40
References 41
.VI
xvi Contents
3. Radiologic Staging of Lung Cancer 47
Kitt Shaffer
I. Introduction 47
II. Historical Perspective 47
III. Chest Radiograph 49
IV. Intrathoracic Staging with Chest CT 50
V. Intrathoracic Staging with Chest MR 54
VI. Staging of Distant Metastases 58
VII. Staging with PET and Nuclear Medicine 71
VIII. Conclusion 73
References 75
4. Non Small Cell Lung Cancer Surgical Staging 79
Raja M. Flores, Jose J. Norberto, Michael T. Jaklitsch, and
David J. Sugarbaker
I. Introduction 79
II. History 80
III. TNM Classification Revisions in 1997 80
IV. Procedures of Surgical Pathological Staging 89
V. Summary 96
References 97
Part Two NON SMALL CELL LUNG CANCER
5. Role of Video Assisted Thoracic Surgery in the Diagnosis and
Treatment of Non Small Cell Lung Cancer 103
Steven J. Mentzer
I. Introduction 103
II. Operative Principles 104
III. Pleural Disease 105
IV. Solitary Nodule 105
V. Surgical Staging 106
VI. Anatomic Resections 108
References 110
6. Non Small Cell Lung Cancer: Surgery for Stage I and II Disease 113
Malcolm M. DeCamp, Jr. and Raja M. Flores
I. Introduction 113
Contents xvii
II. Diagnosis: The Solitary Pulmonary Nodule 114
III. Staging 115
IV. Defining Early Stage Disease 117
V. Approach to Resection 121
VI. Surgical Results 127
VII. Summary 131
References 132
7. Randomized Trials in Stage I and II Non Small Cell
Lung Cancer 135
Victoria J. Dorr and Michael C. Perry
I. Introduction 135
I. Radiation Therapy 137
III. Chemotherapy 138
IV. Adjuvant Immunotherapy 146
V. Conclusion 151
References 153
8. Superior Pulmonary Sulcus Tumors 159
Harold C. Urschel, Jr.
I. Introduction 159
II. History 159
III. Diagnosis 160
IV. Indications for Surgery 165
V. Treatment 166
VI. Conclusion 176
References 184
9. Surgery for Advanced Lung Cancer 191
Raphael Bueno
I. Introduction 191
II. T4 Tumors 191
III. Stage IIIB: Surgical Treatment for N3 Disease 201
IV. Resection of Lung Cancer in the Presence of
Metastatic Disease 201
V. Conclusion 202
References 202
xviii Contents
10. Multimodality Therapy for Stage IIIA and IIIB
Non Small Cell Lung Cancer 207
Gary M. Strauss and Elizabeth H. Baldini
I. Introduction 207
II. Single Modality Treatment 208
III. Combined Modality Treatments 211
IV. Conclusions 218
References 219
11. Multimodality Therapy of Stage IIIB Non Small Cell
Lung Cancer 225
Scott J. Swanson
I. Introduction 225
II. Stage IIIB Non Small Cell Lung Cancer 225
III. Chemotherapy and Radiation Treatment for Stage IIIB
Lung Cancer 226
IV. Surgical Treatment of Stage IIIB Non Small Cell Lung Cancer 228
V. Conclusion 231
References 232
12. Chemotheraphy of Advanced Non Small Cell Lung Cancer 235
Nam H. Dang, Roy S. Herbst, and Arthur T. Skarin
I. Introduction 235
II. Pretreatment Prognostic Factors in NSCLC Patients 236
III. Single Agents Active in NSCLC 238
IV. Development of Combination Regimens 242
V. Randomized Studies Comparing Chemotherapy
to Supportive Care 248
VI. Meta Analyses 252
VII. New Agents in Lung Cancer 253
VIII. New Drug Combinations in NSCLC 260
IX. Second Line Therapy for NSCLC 265
X. Quality of Life 266
XI. Conclusion t^o
_ „ 268
References 271
Contents xix
13. Multimodality Therapy for Non Small Cell Cancer Metastases
to the Brain 281
Rodolfo Hakim, Eben Alexander III, Peter McL. Black,
and Jay S. Loeffler
I. Introduction 281
II. Frequency 282
III. Method of Spread and Distribution from the Lungs 282
IV. Clinical Manifestations 283
V. Diagnosis 285
VI. Treatment 285
VII. Solitary NSCLC Brain Metastases—Brigham and Women s
Hospital Experience 292
VIII. Summary 294
References 297
14. Laboratory Models to Evaluate New Agents for the Systemic
Treatment of Lung Cancer 301
Beverly A. Teicher and Emil Frei HI
I. Introduction 301
II. Syngeneic Models: Lewis Lung Carcinoma 302
III. Human Cell Lines and Xenografts 324
IV. Conclusion 329
References 329
Part Three SMALL CELL LUNG CANCER
15. Surgery for Small Cell Lung Cancer 337
Dean M. Donahue and Douglas J. Mathisen
I. Introduction 337
II. Historical Background 338
III. Role of Surgery in Staging SCLC 338
IV. Role of Surgery in Treatment of Early Stage SCLC 339
V. Role of Surgery Combined with Chemotherapy 340
VI. Role of Surgery in Multimodality Therapy 343
VII. Conclusion 347
References 347
xx Contents
16. Role of Thoracic Radiation Therapy and Prophylactic Cranial
Irradiation in the Management of Small Cell Lung Cancer 351
Parvesh Kumar
I. Introduction 351
II. Staging System 352
III. Thoracic Radiation Therapy 352
IV. Prophylactic Cranial Irradiation 365
References 376
17. Chemotherapy of Small Cell Lung Cancer 381
Anthony L Boral ami Thomas J. Lynch. Jr.
I. Introduction 381
II. Single Agent Chemotherapy in SCLC 384
III. Combination Chemotherapy in SCLC 386
IV. Novel Therapeutic Approaches 394
V. Conclusions 395
References 396
18. High Dose Therapy for Small Cell Lung Cancer with Stem
Cell Support 405
Anthony D. Elias
1. Introduction 405
II. Dose Intensity 406
III. Future Directions 411
IV. Conclusion 414
References 415
Author lnJr 42J
Subjttt Ithltw 457
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| isbn | 0824702360 |
| language | English |
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| series | Lung biology in health and disease |
| series2 | Lung biology in health and disease |
| spelling | Multimodality treatment of lung cancer ed. by Arthur T. Skarin New York [u.a.] Dekker 2000 XX, 472 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Lung biology in health and disease 140 Carcinoma, Non-Small-Cell Lung therapy Carcinoma, Small Cell therapy Combined Modality Therapy Lung Neoplasms therapy Lungs Cancer Treatment Therapie (DE-588)4059798-2 gnd rswk-swf Lungenkrebs (DE-588)4036668-6 gnd rswk-swf Kombinationstherapie (DE-588)4194534-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lungenkrebs (DE-588)4036668-6 s Kombinationstherapie (DE-588)4194534-7 s DE-604 Therapie (DE-588)4059798-2 s Skarin, Arthur T. Sonstige oth Lung biology in health and disease 140 (DE-604)BV000008326 140 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008787225&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Multimodality treatment of lung cancer Lung biology in health and disease Carcinoma, Non-Small-Cell Lung therapy Carcinoma, Small Cell therapy Combined Modality Therapy Lung Neoplasms therapy Lungs Cancer Treatment Therapie (DE-588)4059798-2 gnd Lungenkrebs (DE-588)4036668-6 gnd Kombinationstherapie (DE-588)4194534-7 gnd |
| subject_GND | (DE-588)4059798-2 (DE-588)4036668-6 (DE-588)4194534-7 (DE-588)4143413-4 |
| title | Multimodality treatment of lung cancer |
| title_auth | Multimodality treatment of lung cancer |
| title_exact_search | Multimodality treatment of lung cancer |
| title_full | Multimodality treatment of lung cancer ed. by Arthur T. Skarin |
| title_fullStr | Multimodality treatment of lung cancer ed. by Arthur T. Skarin |
| title_full_unstemmed | Multimodality treatment of lung cancer ed. by Arthur T. Skarin |
| title_short | Multimodality treatment of lung cancer |
| title_sort | multimodality treatment of lung cancer |
| topic | Carcinoma, Non-Small-Cell Lung therapy Carcinoma, Small Cell therapy Combined Modality Therapy Lung Neoplasms therapy Lungs Cancer Treatment Therapie (DE-588)4059798-2 gnd Lungenkrebs (DE-588)4036668-6 gnd Kombinationstherapie (DE-588)4194534-7 gnd |
| topic_facet | Carcinoma, Non-Small-Cell Lung therapy Carcinoma, Small Cell therapy Combined Modality Therapy Lung Neoplasms therapy Lungs Cancer Treatment Therapie Lungenkrebs Kombinationstherapie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008787225&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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