Cytokines in pulmonary disease: infection and inflammation
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Dekker
2000
|
| Schriftenreihe: | Lung biology in health and disease
141 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 598 S. Ill., graph. Darst. |
| ISBN: | 082471931X |
Internformat
MARC
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| 245 | 1 | 0 | |a Cytokines in pulmonary disease |b infection and inflammation |c ed. by Steve Nelson ... |
| 264 | 1 | |a New York [u.a.] |b Dekker |c 2000 | |
| 300 | |a XIX, 598 S. |b Ill., graph. Darst. | ||
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| 490 | 1 | |a Lung biology in health and disease |v 141 | |
| 650 | 7 | |a Cytokines |2 cabt | |
| 650 | 7 | |a Respiratory Diseases |2 cabt | |
| 650 | 4 | |a Cytokines |x Immunology | |
| 650 | 4 | |a Cytokines |x Physiological effect | |
| 650 | 4 | |a Cytokines |x immunology | |
| 650 | 4 | |a Cytokines |x physiology | |
| 650 | 4 | |a Lung Diseases |x immunology | |
| 650 | 4 | |a Lung |x immunology | |
| 650 | 4 | |a Lungs |x Diseases |x Immunological aspects | |
| 650 | 4 | |a Lungs |x Immunology | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-008787203 | ||
Datensatz im Suchindex
| _version_ | 1804127596386975744 |
|---|---|
| adam_text | CONTENTS
Series Introduction (Claude Lenfant) «/
Preface v
Contributors vii
1. Cytokines and Pulmonary Host Defense Against Microbes 1
Galen B. Toews
I. Introduction 1
II. Innate Immunity 2
III. Specific Immunity 7
IV. Conclusions 10
References 10
2. Cytokine Networks and Leukocyte Recruitment 19
Steven L. Kunkel, Stephen W. Chensue, Lisa Colletti,
Theodore Standiford, Nicholas Lukacs, and Robert M. Strieter
I. Biology of Cytokines in Inflammation 20
xiii
xiv Contents
II. Leukocyte Chemotaxis and Organ System Derived
Cytokine Networks 24
III. Summary 31
References 32
3. Cytokines and the Resolution of Lung Inflammation 37
Jason Kelley
I. Introduction 37
II. Resolution of Pneumonia 39
III. Proinflammatory Cytokines Released During Inflammation 42
IV. Fibrogenic Cytokines Released During Inflammation 43
V. Cytokines That Promote the Resolution of Inflammation 44
VI. Potential Roles of Trophic Cytokines 45
VII. Environmental and Genetic Influences on Cytokines
and Resolution of Inflammation 46
VIII. Regulation of Fibrinolysis During Resolution of
Inflammation 48
IX. Summary 50
References 50
4. Transgenic Mice as Models of Cytokine Function in the Lung 55
David B. Lewis
I. Cytokines: General Considerations 55
II. Features of the Major Cytokine Families 58
HI. Transgenes and Targeted Gene Disruption 59
IV. Cytokine Mediated Events in Lung Host Defense
Defined Using Transgenic or Gene Knock Out Mice 65
V. Summary 73
References 74
5. Cytokines in Cell Mediated Immune Responses 83
Anthony O Regan and David M. Center
I. Introduction 83
II. Thl Th2 Paradigm: Relationship to Cell Mediated
Immunity 84
III. Essential Cytokines in the Type 1 Response 86
IV. Type 1 Cytokines in Infectious Disease 102
Contents xv
V. Relevance to the Lung and Conclusions 105
References 107
6. Cytokines and Pleural Disease 117
Veena B. Antony and Kamal Abdul Mohammed
I. Cellular Events During Pleural Inflammation 118
II. Chemokines in Parapneumonic Effusions 122
III. Cytokines and the Pathogenesis of Empyema 123
IV. Cytokines and Granulomatous Disease of the Pleura 125
V. Effect of Cytokines on Resident Cells, Recruited Cells,
and Extracellular Matrix 126
References 127
7. Cytokines and the Antibacterial Defenses of the Lung 131
Steve Nelson, Gregory J. Bagby, Carol M. Mason, and
Warren R. Summer
I. Tumor Necrosis Factor a 132
II. The Chemokines 139
III. Interleukin 10 140
IV. Interleukin 12 141
V. Interferon y 141
VI. Colony Stimulating Factors 143
VII. Conclusion 148
References 148
8. Cytokines in Legionella pneumophila Infections 155
David R. Park and Shawn J. Skerrett
I. Introduction 155
II. Individual Cytokines in Legionellosis 158
III. Pathways of Cytokine Induction by L. pneumophila 177
IV. Interference with Cytokine Responses by L. pneumophila 179
V. Conclusion: Cytokine Therapy for Legionellosis? 179
References 180
9. Tuberculosis 189
Peter F. Barnes
I. Immune Defenses Against Tuberculosis 189
II. Cytokines Produced by Mononuclear Phagocytes 190
xvi Contents
III. Role of T Cell Subpopulations in Protective Immunity 196
IV. Interaction Between M. tuberculosis and HIV 200
V. Cytokines Produced by T Cells 197
VI. Cytokine Modulation in Treatment of Tuberculosis 201
VII. Cytokine Modulation in Prevention of Tuberculosis 203
References 203
10. Nontuberculous Mycobacteria 213
Felix J. Sangari and Luiz E. Bermudez
I. Introduction 213
II. Mechanisms of Infection 215
III. Role of Immune Cells in the Host Defense Against
M. avium 218
IV. Interaction of M. avium with Human Immunodeficiency
Virus 224
V. Potential Therapeutic Strategies 226
VI. Conclusions 227
References 227
11. Cytokines and Pulmonary Infection with Pneumocystis carinii 235
Judd E. Shellito and James M. Beck
I. Introduction 235
II. Microbiology of Pneumocystis carinii 236
III. Clinical Features of Pneumocystis carinii Pneumonia 236
IV. Host Defenses Against Pneumocystis carinii Infection 237
V. Specific Cytokines Associated with Pneumocystis carinii
Infection 239
VI. Conclusions and Future Directions 247
References 247
12. Rationale and Experimental Support for Cytokine Therapy
of Fungal Pneumonias 253
Jeffrey L. Curtis and Galen B. Toews
I. Cryptococcus neoformans 255
II. Candida albicans 267
III. Host Defenses and Cytokine Therapy in Other Fungal
Pneumonias 273
Contents xvii
IV. Summary and Conclusions 275
References 276
13. Role of Viruses in Cytokine Induction from Lung Cells 293
Lois J. Geist and Gary W. Hunninghake
I. Introduction 293
II. Role of Viruses in Lung Disease 294
HI. Viruses and Activation of Cytokine Genes 295
IV. Role of Transcription Factors in Viral Regulation of
Cytokine Genes: Nuclear Factor Kappa B 298
V. Summary 300
References 300
14. Cytokines in Cystic Fibrosis 307
Robert W. Wilmott
I. Introduction 307
II. Cystic Fibrosis 308
III. Clinical Data 310
IV. Targets for Therapy 321
V. Conclusions 324
References 325
15. HIV 1, Cytokines, and the Lung 331
Thomas L. Benfield, Henry Masur, and Jens D. Lundgren
I. HIV 1 Infection 332
II. HIV 1 Infection of the Lower Respiratory Tract 339
III. Conclusion 353
IV. Perspectives 353
References 354
16. Cytokines in Pulmonary Transplantation 365
Si M. Pham, Surindra N. Mitruka, and Sen Li
I. Introduction 365
II. Overview of Cytokines in Transplantation 367
III. Cytokine Network in Lung Transplantation 369
IV. Cytokine Based Therapies in Organ Transplantation 382
xviii Contents
V. Cytokine Profiles and Novel Therapeutic Strategies in
Lung Transplantation 383
VI. Conclusion 387
References 389
17. Extrapulmonary Sepsis and Cytokines in Lung Injury
and Defense 403
Thomas R. Martin, Gustavo Matute Bello, Shawn J. Skerrett,
and Charles W. Frevert
I. Introduction and Definition of Terms 403
II. Clinical Links Among Bacteremia, Sepsis, and Lung Injury 405
HI. Effects of Extrapulmonary Infections on the Lungs 411
IV. Pathogenetic Factors That Link Systemic Infection and
Lung Injury 413
V. Nonpulmonary Infection and Lung Injury: Clues to
Pathogenesis from Human Studies 419
VI. Nonpulmonary Infection and Lung Injury: Clues from
Experimental Studies 423
VII. Effects of Nonpulmonary Infections on Lung Antibacterial
Defenses 428
VIII. New Cytokine Related Treatments, Tried and Untried 430
IX. Major Unanswered Questions and Future Directions 437
References 437
18. Gene Therapy, Cytokines, and Host Defense 459
Jay K. Kolls, Elizabeth R. Rhoades, and Theodore Standiford
I. Introduction 459
II. Vector Systems for Pulmonary Gene Delivery 460
III. Candidate Cytokine Genes 463
IV. Results in Disease Models 465
V. Conclusions 474
References 474
19. Cytokines and Host Defense: A Clinician s View 481
Qanta A. A. Ahmed and Michael S. Niederman
I. Introduction 481
II. Role of Cytokines in Common Forms of Pneumonia 482
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| indexdate | 2024-07-09T18:35:52Z |
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| spelling | Cytokines in pulmonary disease infection and inflammation ed. by Steve Nelson ... New York [u.a.] Dekker 2000 XIX, 598 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Lung biology in health and disease 141 Cytokines cabt Respiratory Diseases cabt Cytokines Immunology Cytokines Physiological effect Cytokines immunology Cytokines physiology Lung Diseases immunology Lung immunology Lungs Diseases Immunological aspects Lungs Immunology Atemwegsinfektion (DE-588)4250190-8 gnd rswk-swf Cytokine (DE-588)4205701-2 gnd rswk-swf Lungenkrankheit (DE-588)4036660-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lungenkrankheit (DE-588)4036660-1 s Cytokine (DE-588)4205701-2 s DE-604 Atemwegsinfektion (DE-588)4250190-8 s Nelson, Steve Sonstige oth Lung biology in health and disease 141 (DE-604)BV000008326 141 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008787203&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Cytokines in pulmonary disease infection and inflammation Lung biology in health and disease Cytokines cabt Respiratory Diseases cabt Cytokines Immunology Cytokines Physiological effect Cytokines immunology Cytokines physiology Lung Diseases immunology Lung immunology Lungs Diseases Immunological aspects Lungs Immunology Atemwegsinfektion (DE-588)4250190-8 gnd Cytokine (DE-588)4205701-2 gnd Lungenkrankheit (DE-588)4036660-1 gnd |
| subject_GND | (DE-588)4250190-8 (DE-588)4205701-2 (DE-588)4036660-1 (DE-588)4143413-4 |
| title | Cytokines in pulmonary disease infection and inflammation |
| title_auth | Cytokines in pulmonary disease infection and inflammation |
| title_exact_search | Cytokines in pulmonary disease infection and inflammation |
| title_full | Cytokines in pulmonary disease infection and inflammation ed. by Steve Nelson ... |
| title_fullStr | Cytokines in pulmonary disease infection and inflammation ed. by Steve Nelson ... |
| title_full_unstemmed | Cytokines in pulmonary disease infection and inflammation ed. by Steve Nelson ... |
| title_short | Cytokines in pulmonary disease |
| title_sort | cytokines in pulmonary disease infection and inflammation |
| title_sub | infection and inflammation |
| topic | Cytokines cabt Respiratory Diseases cabt Cytokines Immunology Cytokines Physiological effect Cytokines immunology Cytokines physiology Lung Diseases immunology Lung immunology Lungs Diseases Immunological aspects Lungs Immunology Atemwegsinfektion (DE-588)4250190-8 gnd Cytokine (DE-588)4205701-2 gnd Lungenkrankheit (DE-588)4036660-1 gnd |
| topic_facet | Cytokines Respiratory Diseases Cytokines Immunology Cytokines Physiological effect Cytokines immunology Cytokines physiology Lung Diseases immunology Lung immunology Lungs Diseases Immunological aspects Lungs Immunology Atemwegsinfektion Cytokine Lungenkrankheit Aufsatzsammlung |
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