Expanding indications for the new macrolides, azalides, and streptogramins:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Dekker
1997
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| Schriftenreihe: | Infectious disease and therapy
21 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 664 S. Ill. |
| ISBN: | 0824700562 |
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| 100 | 1 | |a Zinner, Stephen H. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Expanding indications for the new macrolides, azalides, and streptogramins |c ed. by Stephen H. Zinner ... |
| 264 | 1 | |a New York [u.a.] |b Dekker |c 1997 | |
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| adam_text | Contents
Series Introduction Hi
Preface v
Contributors to Plenary Sessions and Workshops xix
PLENARY SESSIONS
1. Overview of the Clinical Use of Macrolides
and Streptogramins 3
Roger G. Finch
2. Postantibiotic Effects and the Dosing of Macrolides,
Azalides, and Streptogramins 27
William A. Craig
3. Ketolides: New Semisynthetic 14 Membered
Ring Macrolides 39
Andre Bryskier, Constantin Agouridas, and
Jean Francois Chantot
4. Streptogramins: From Parenteral to Oral 51
Daniel H. Bouanchaud
5. Azalides: Basic and Clinical Research 67
Michael W. Dunne
6. Basic and Clinical Research on Macrolides 75
J Carl Craft
vii
viii Contents
7. Nonantibiotic Effects of Macrolide Antibiotics: Suppression
of the Bacterial Glycocalyx of Pseudomonas aeruginosa
Isolates from Patients with Cystic Fibrosis 91
Charles W. Stratton
8. Effects of Macrolides on Leukocytes and Inflammation 101
Marie Therese Labro
9. Animal Uses of Macrolides and Related Antibiotics 117
Jean Pierre Lafont, Elisabeth Chaslus Dancla, and
Jean Louis Martel
10. The New Macrolides for Treatment of Pediatric Infections:
Roundtable Discussion 131
George H. McCracken, Jr., Urs B. Schaad, and
M. J. Tarlow
11. The Molecular Mechanism of Action of Streptogramins and
Related Antibiotics 145
C. Cocito, M. Di Giambattista, E. Nyssen, and P. Vannuffel
12. Early Clinical Results with Quinupristin/Dalfopristin
for the Therapy of Bacteremia Due to Resistant
Gram Positive Bacteria 173
Robert C. Moellering, Jr., and Sharon L. Cerwinka
13. Drug Interactions of Macrolides and Azalides 177
Ethan Rubinstein and Shlomo Segev
14. Macrolides, Azalides, and Streptogramins in Treatment of
Opportunistic Infections in Immunocompromised Patients 189
Jack S. Remington
WORKSHOPS
15. Legionella and Spirochetes 207
/. M. Hoepelman and Daniel M. Musher
16. Mycoplasma and Chlamydia 219
J. Thomas Grayston and Pentti Huovinen
17. Staphylococci, Streptococci, and Pneumococci 225
Jacques F. Acar and Josi Melo Cristino
18. Pharmacokinetics and Pharmacodynamics 233
Charles H. Nightingale and Fritz Sorgel
Contents ix
19. Campylobacter and Helicobacter pylori 237
Jean Paul Butzler and Francis Megraud
20. Haemophilus influenzae, Enterococci, and Anaerobes 251
Vincent T. Andriole and Ian Phillips
21. The Newer Macrolides, Azalides, and Streptogramins for
the Management of HIV Associated Opportunistic
Infections 257
Kenneth H. Mayer and J. Allen McCutchan
22. Special Pathogens 267
John E. McGowan, Jr., and Joel Ruskin
EXTENDED ABSTRACTS
I. NEW AGENTS
Ketolides: A New Class of Macrolide Antibacterials—Structural
Characteristics and Biological Properties of RU 004 279
Constantin Agouridas, Y. Benedetti, A. Bonnefoy, P. Collette,
A. Denis, P. Mauvais, G. Labbe, and Jean Francois Chantot
Isolation of an Antifungal Macrolide from Soil Sample
Nocardioides Strain: Production and Structure Elucidation 286
V. Loppinet, L. Hilali, N. Youssef, R. Bonaly, and C. Finance
n. LEGIONELLA, SPIROCHETES
Azithromycin in the Treatment of Community Acquired
Legionnaires Disease 295
/. Kuzman, S. Schonwald, and J. Culig
Temperature Dependence of MIC and MBC of Roxithromycin
Against Borrelia burgdorferi In Vitro 299
/. Wendelin, R. Gasser, and E. C. Reisinger
Tolerability of Treatment with 3 g of Azithromycin Given
in 5 Days 303
Franc Strle, Vera Maraspin, Stanka Lotrit Furlan, and
Joie Cimperman
Azithromycin in the Treatment of Erythema Migrans 307
/. GoriSek and J. Rogl
x Contents
Follow up Study of Patients with Syphilis Treated with
Azithromycin 311
A. L. Mashkilleyson and M. A. Gomberg
III. MYCOPLASMA, CHLAMYDIA
A Comparison of the In Vitro Sensitivity of Chlamydia
pneumoniae to Macrolides and a New Benzoxazinorifamycin,
KRM 1648 317
C. C. Kuo, J. Thomas Grayston, T. Hidaka, and L. M. Rose
Susceptibilities to Azithromycin of Isolates of Chlamydia
pneumoniae from Patients with Community Acquired
Pneumonia 322
P. M. Roblin, N. Sokolovskaya, and M. R. Hammerschlag
Azithromycin in Control of Trachoma 326
Julius Schachter
Microbiologic Efficacy of Azithromycin for the Treatment of
Community Acquired Pneumonia Due to Chlamydia
pneumoniae in Children 330
M. R. Hammerschlag, P. M. Roblin, Michael Campbell,
Antonia Kolokathis, M. Powell, and the Pediatric Pneumonia
Study Group
Community Acquired Pneumonia in Children: Underestimation
of Mycoplasma Infection and Efficacy of Macrolides 335
Dominique Gendrel, Josette Raymond, Florence Moulin, Jean
Luc Iniguez, Sophie Ravilly, Pierre Lebon, and Gabriel Kalifa
Ureaplasma urealyticum Isolations from Young Children with
Respiratory Problems 339
Sharon A. Poulin, Ruth B. Kundsin, and Rita D. DeLollis
Could Clarithromycin Prevent Asthma? 343
Rita D. DeLollis, Ruth B. Kundsin, and Sharon A. Poulin
Azithromycin in the Treatment of Chlamydia trachomatis
Infection 349
Z. Dajek
Single Dose Azithromycin in the Treatment of Genital
Chlamydial Infections 352
V. Ferianec, K. Holoman, J. Chmurny, V. Grba, and F. Stano
Contents xi
Single Dose Azithromycin Treatment: A Solution for
Uncomplicated Lower Genital Tract Chlamydial Infection 354
B. Kobal
Report of a Multicenter Clinical Evaluation of Azithromycin in
the Treatment of Nongonococcal Urethritis in Men 358
M. Urban, J. Flek, V. Herman, M. Chaloupka, B. Krdsny,
J. Klamo, D. Pacik, and P. TomaStik
Efficacy of Roxithromycin in Urogenital Infection 361
/. /. Derevianko
IV. STAPHYLOCOCCI, STREPTOCOCCI, PNEUMOCOCCI
Dissociated Macrolide and Lincosamide Resistance in
Streptococcus pneumoniae and Variation of Susceptibility Testing
Methods in Detecting Clindamycin Resistance 369
E. L. Fasola, S. Bajaksouzian, P. C. Appelbaum, and
M. R. Jacobs
Prevalence of Antibiotic Resistance in Streptococcus pyogenes:
Results of a National Multicenter Survey Conducted in Italy
During 1995 376
E. A. Debbia, P. Cipriani, G. P. Gesu, G. Ortisi,
M. G. Menozzi, E. Nani, V. Nicolosi, R. Rigoli, R. Serra,
M. Toni, F. E. Vigand, and G. C. Schito
In Vitro Activity of Some Macrolides Against S. pyogenes 380
G. Tempera, P. M. Furneri, V. Nicolosi, and G. Nicoletti
Antipneumococcal Activity of RP 59500 (an Injectable
Streptogramin), Erythromycin, and Sparfloxacin by MIC and
Rapid Time Kill 385
G. A. Pankuch, M. R. Jacobs, and P. C. Appelbaum
Effect of Macrolide Resistance on the Activity of the Oral
Streptogramin RPR 106972 and Its Components Against
Streptococcus pneumoniae 390
M. R. Jacobs, S. K. Spangler, and P. C. Appelbaum
In Vitro Antibacterial Activity of RU 004, a New Ketolide
Active Against Respiratory Pathogens 395
Constantin Agouridas, A. Bonnefoy, and Jean Frangois Chantot
xii Contents
Antistaphylococcal Activity of Quinupristin/Dalfopristin, a Well
Defined Mixture of Chemically Modified Streptogramins 402
Christof von Eiff and Georg Peters
E Test for Susceptibility Testing of Streptococcus pyogenes to
Azithromycin, Clarithromycin, Erythromycin, and
Roxithromycin 407
Gerard J. van Asselt and Jacobus H. Sloos
Efficacy of Clarithromycin Against Experimental Pulmonary
Infection Caused by Streptococcus pneumoniae Strains with a
Novel Macrolide Resistance Mechanism 411
/. A. Meulbroek, M. J. Mitten, A. Oleksijew, V. D. Shortridge,
S. K. Tanaka, and J. D. Alder
Macro and Microautoradiographic Studies on Penetration of
Azithromycin in Bacterially Infected Mice 415
Issei Nakayama, Emiko Yamaji, Kaoru Shimada, Shuichi
Yokoyama, Kazumi Miura, Hideya Muto, Kazunori Enogaki,
Masatoshi Ogawa, and Kino Shimooka
In Vivo Antibacterial Activity of RU 004, a New Ketolide
Active Against Respiratory Pathogens 421
Constantin Agouridas, A. Bonnefoy, and Jean Frangois Chantot
Open Noncomparative Study of the Efficacy and Safety of
Azithromycin in the Treatment of Adult Tonsilitis
(Epidemiological Study of the Responsible Bacteria) 425
A. Desaulty
An Open Study of Clarithromycin in the Treatment of
Pneumonia Due to Streptococcus pneumoniae 429
Murat Hayran, Mustafa Erman, Deniz Gur, Murat Akova, and
Serhat Unal
Clinical Study of Rokitamycin on Pneumococcal Upper
Respiratory Tract Infections in Pediatrics 432
Yoshikiyo Toyonaga
V. PHARMACOKINETICS, PHARMACODYNAMICS,
DRUG INTERACTIONS
A Comparison of the Bronchopulmonary Pharmacokinetics of
Clarithromycin and Azithromycin 439
Kalpana B. Patel, Dawei Xuan, Charles H. Nightingale, Pamela
R. Tessier, John H. Russomanno, and Richard Quintiliani
Contents xiii
Kinetics of Dirithromycin: Concentrations in Tonsils, Bronchial
Mucosa, and Secretions. Multiple Dose Studies 447
C. Muller Serieys, E. Bergogne Berezin, F. Lemaitre,
M. Derriennic, A. Oksman, P. Gehanno, C. Le Royer, and
J. Clavier
A Human Model of Local Abscess Using Skin Chambers: The
Penetration of Azithromycin and the Chemiluminescence
Response of Neutrophils (PMN) 455
K. Takahashi, V. Duchateau, M. Husson, A. M. Bourguignon,
and F. Crokaert
Separation of Presystemic and Post Absorptive Influences on the
Bioavailability of Azithromycin in Cynomolgus Monkeys 460
G. Foulds, A. G. Connolly, J. H. Fortner, and A. M. Fletcher
Clinical Pharmacology of Azithromycin Given at Various Sites
Along the Gastrointestinal Tract in Healthy Subjects 464
David R. Luke, G. Foulds, Joseph Scavone, Hylar L. Friedman,
and William J. Curatolo
Effect of Food and Formulation on Bioavailability of
Azithromycin 469
G. Foulds, David R. Luke, S. A. Willavize, William J. Curatolo,
Hylar L. Friedman, M. J. Gardner, R. A. Hansen, R. Teng, and
J. Vincent
Rectal Azithromycin in Healthy Subjects 474
David R. Luke, G. Foulds, G. Melnik, Paden C. Going, and
Valerie Lawrence
Comparative Pharmacodynamics of Clarithromycin and
Azithromycin Against Respiratory Tract Pathogens 478
A. Bauernfeind, R. Jungwirth, and E. Eberlein
VI. HELICOBACTER PYLORI, CAMPYLOBACTER
Comparison of Clarithromycin Efficacy in Ferrets and Humans
for Treatment of Helicobacter lnduced Gastritis 487
P. Ewing, J. D. Alder, M. J. Mitten, A. Conway, A. Oleksijew,
K. Jarvis, L. Paige, and S. K. Tanaka
Azithromycin/Ranitidine Combined Treatment of Helicobacter
pylori in Patients with Duodenal Ulcer and Chronic Gastritis:
A Pilot Study 493
B. Desnica, V. Burek, and N. Makek
xiv Contents
Azithromycin as a Promising Part of Helicocidal Regimens 498
O. Shonovd, P. Petr, and O. Hausner
VII. ANAEROBES, ENTEROCOCCI, HAEMOPHILUSINFLUENZAE
Comparative In Vitro Activity of Five Macrolides Against
Gram Positive Cocci, Campylobacter Species, and Anaerobes 505
M. Marina, K. Ivanovo, N. Hadjieva, and A. Urumov
Prophylactic Effect of Azithromycin on Experimentally Induced
Intraabdominal Infection in Rats 511
N. Panovski, P. MiloSevski, and N. Labatevski
Are Macrolides Active Against Haemophilus influenzae? Are In
Vitro Tests Reliable? 516
F. Crokaert, M. Aoun, V. Duchateau, H. Goossens, P. Grenier,
A. Vandermies, and J. Klastersky
Macrolide Susceptibility of Isolates of Haemophilus influenzae,
Streptococcus pneumoniae, and Moraxella catarrhalis from
Patients with Community Acquired Lower Respiratory Tract
Infection—Results of an International Multicenter Study (the
Alexander Project), 1992 1994 523
D. Felmingham, J. Linares, and the Alexander Project Group
Resistance of Common Respiratory Pathogens to Erythromycin
and Azithromycin 528
Milan Cizman, Ana Zlata DragaS, Katja Seme, Andreja Orazem,
and Metka Paragi
Efficacy of Clarithromycin and Azithromycin at Human
Pharmacological Dosage Against Experimental Haemophilus
influenzae Pulmonary Infection 533
/. D. Alder, M. J. Mitten, A. Conway, A. Oleksijew, K. Jarvis,
L. Paige, and S. K. Tanaka
VIII. MYCOBACTERIA AND OTHER INFECTIONS IN
HIV INFECTED PERSONS
Clarithromycin 500 mg BID as Prophylaxis for MAC Disease—
A Follow up Review 539
John T. Sinnott, Douglas A. Holt, Sally H. Houston, Gary
Bergen, Pamela Sakalosky, Julie A. Larkin, and Richard Oehler
Contents xv
Clarithromycin Prophylaxis for Disseminated Mycobacterium
avium Infection 544
T. M. File, Jr., D. C. Claypoole, S. J. Longstreth, D. J. Signs,
W. H. Ruby, and A. S. Indorf
Azithromycin + Pentamidine + Pyrimethamine in the
Prophylaxis of Opportunistic Infections in HIV Positive Patients
with CD4 Count Less Than 200 549
G. Barbarini, G. Garavelli, G. Barbaro, B. Grisorio,
A. Lucchini, S. Lopez, G. Del Buono, S. Edo, and P. Alcini
IX. SPECIAL PATHOGENS
Human and Animal Bite Wounds: Bacteriology, Macrolide
Susceptibility, and Therapeutic Potential 555
Ellie J. C. Goldstein and Diane M. Citron
Azithromycin in the Treatment of Pertussis in Children:
A Pilot Study 559
A. Bate, N. Kuzmanovit, and T. Zrnic
The Use of New Macrolides in Experimental Brucella
melitensis Infection 563
R. Lang, D. Torten, B. Shasha, and Ethan Rubinstein
X. NONANTIBACTERIAL EFFECTS
In Vivo Effect of Azithromycin Subinhibitory Concentrations
on the Mortality of Experimental Pseudomonas aeruginosa
Sepsis 571
M. N. Marangos, M. E. Klepser, D. P. Nicolau, Charles H.
Nightingale, and Richard Quintiliani
Clarithromycin Reduces Cl Dependent Transepithelial Potential
Difference in Tracheal Mucosa of Anesthetized Rabbits 576
/. Tamaoki, H. Takemura, E. Tagaya, Y. Takeda, and K. Konno
Inhibition of Adherence of Klebsiella pneumoniae Strains to
Intestine 407 Cell Lines by Roxithromycin 581
5. Favre Bonte, C. Forestier, A. Darfeuille Michaud, C. Rich,
J. Sirot, and B. Joly
Clinical and Immunological Study of Roxithromycin on
Infectious Diseases in Obstetrics and Gynecology 586
K. Izumi, H. Mikamo, K. Kawazoe, and T. Tamaya
xvi Contents
XI. CLINICAL STUDIES: OTITIS MEDIA
Five Day Treatment of Acute Otitis Media in Children with
Clarithromycin 593
Dimitris A. Kafetzis, Theodore Bairamis, Dimitra Dinopoulou,
Stamatina Vlachou, and Nicholas Apostolopoulos
Azithromycin Versus Amoxicillin for Acute Otitis Media
Prophylaxis 597
Nicola Principi, Paola Marchisio, Emanuela Sala, Luisa
Lanzoni, and Stefania Sorella
XII. CLINICAL STUDIES: BRONCHITIS
Azithromycin for the Treatment of Community Acquired
Bronchitis: A Large Multicenter Efficacy Tolerance Trial 605
F. Raffi
Safety and Efficacy of Clarithromycin Compared with
Cefpodoxime Proxetil in the Treatment of Acute Exacerbation
of Chronic Obstructive Pulmonary Disease 609
P. Leophonte and J. P. Chauvin
XIII. CLINICAL STUDIES: PNEUMONIA
Randomized Comparative Trial of the Safety, Efficacy, and Cost
of Intravenous Cefuroxime Plus Intravenous Erythromycin
Versus Intravenous Cefuroxime Plus Oral Clarithromycin in the
Therapy of Community Acquired Pneumonia 617
D. Skupien, A. Margulis, N. Kaczander, S. Jaworski,
A. Ekleberry, J. Pypkowski, and M. J. Zervos
Azithromycin in the Treatment of Community Acquired
Pneumonia 626
K. Golec, M. Rzeszutko Grabowska, and D. Bukowska
Nierojewska
Azithromycin: 3 Day Versus 5 Day Dosage Regimen for
Community Acquired Pneumonia in Children 629
B. Ficnar, N. Huzjak, I. Klinar, and M. Matrapazovski
Single Dose Azithromycin in the Treatment of Atypical
Pneumonia: A Pilot Study 634
5. Schonwald, I. Kuzman, V. Car, J. Culig, and K. OreSkovic
Contents xvii
XIV. CLINICAL STUDIES: OTHER RESPIRATORY INFECTIONS
Azithromycin in the Treatment of Patients with Upper
Respiratory Tract Infections, Comparison of 3 Day and
5 Day Regimens 641
P. Dolezal, M. KroSldk, and J. Kladansky
Clinical and Bacteriological Evaluation of Clarithromycin (50 mg
Tablets) in Children with Lower Respiratory Tract Infection 645
Yoshikiyo Toyonaga
Experience with Improved Compliance of Clarithromycin
Granules in Children 649
Keisuke Sunakawa, Hironobu Akita, Satoshi Iwata, Yoshitake
Satoh, Tatsuo Aoyama, and Ryochi Fujii
Efficacy and Tolerability of Azithromycin Versus Josamycin in
the Treatment of Children with Lower Respiratory Tract
Infections 656
Ste~pdn Kutilek, Jozef Hoza, Daniela Markovd, and Milan Bayer
Azithromycin in the Treatment of Respiratory Tract Infections
in Children 660
K. Galova, I. Marinova, J. Hractova, Z. Kukova, S. Krizan,
S. Sufliarska, H. Cintalanova, and A. Nogeova
Efficacy of Roxithromycin in Elderly and Middle Aged Patients
with Respiratory Tract Infections 664
S. Yakovlev
XV. OTHER CLINICAL STUDIES
Experience with Azithromycin as Prophylaxis in Transrectal
Biopsy of the Prostate 671
M. Kvarantan and C. Dohoczky
Author Index 675
Subject Index 681
|
| any_adam_object | 1 |
| author | Zinner, Stephen H. |
| author_facet | Zinner, Stephen H. |
| author_role | aut |
| author_sort | Zinner, Stephen H. |
| author_variant | s h z sh shz |
| building | Verbundindex |
| bvnumber | BV012805735 |
| classification_rvk | XI 3505 |
| ctrlnum | (OCoLC)633753753 (DE-599)BVBBV012805735 |
| discipline | Medizin |
| format | Book |
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| genre | (DE-588)1071861417 Konferenzschrift 1996 Lissabon gnd-content |
| genre_facet | Konferenzschrift 1996 Lissabon |
| id | DE-604.BV012805735 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:33:59Z |
| institution | BVB |
| isbn | 0824700562 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008709788 |
| oclc_num | 633753753 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 664 S. Ill. |
| publishDate | 1997 |
| publishDateSearch | 1997 |
| publishDateSort | 1997 |
| publisher | Dekker |
| record_format | marc |
| series | Infectious disease and therapy |
| series2 | Infectious disease and therapy |
| spelling | Zinner, Stephen H. Verfasser aut Expanding indications for the new macrolides, azalides, and streptogramins ed. by Stephen H. Zinner ... New York [u.a.] Dekker 1997 664 S. Ill. txt rdacontent n rdamedia nc rdacarrier Infectious disease and therapy 21 Makrolide (DE-588)4168683-4 gnd rswk-swf Streptogramine (DE-588)4183666-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1996 Lissabon gnd-content Makrolide (DE-588)4168683-4 s Streptogramine (DE-588)4183666-2 s DE-604 Infectious disease and therapy 21 (DE-604)BV001854049 21 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008709788&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Zinner, Stephen H. Expanding indications for the new macrolides, azalides, and streptogramins Infectious disease and therapy Makrolide (DE-588)4168683-4 gnd Streptogramine (DE-588)4183666-2 gnd |
| subject_GND | (DE-588)4168683-4 (DE-588)4183666-2 (DE-588)1071861417 |
| title | Expanding indications for the new macrolides, azalides, and streptogramins |
| title_auth | Expanding indications for the new macrolides, azalides, and streptogramins |
| title_exact_search | Expanding indications for the new macrolides, azalides, and streptogramins |
| title_full | Expanding indications for the new macrolides, azalides, and streptogramins ed. by Stephen H. Zinner ... |
| title_fullStr | Expanding indications for the new macrolides, azalides, and streptogramins ed. by Stephen H. Zinner ... |
| title_full_unstemmed | Expanding indications for the new macrolides, azalides, and streptogramins ed. by Stephen H. Zinner ... |
| title_short | Expanding indications for the new macrolides, azalides, and streptogramins |
| title_sort | expanding indications for the new macrolides azalides and streptogramins |
| topic | Makrolide (DE-588)4168683-4 gnd Streptogramine (DE-588)4183666-2 gnd |
| topic_facet | Makrolide Streptogramine Konferenzschrift 1996 Lissabon |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008709788&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV001854049 |
| work_keys_str_mv | AT zinnerstephenh expandingindicationsforthenewmacrolidesazalidesandstreptogramins |