Introduction to bioinformatics:
Gespeichert in:
Hauptverfasser: | , |
---|---|
Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Harlow [u.a.]
Prentice Hall
1999
|
Ausgabe: | 1. publ. |
Schriftenreihe: | Cell and molecular biology in action series
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XX, 218 S. graph. Darst. |
ISBN: | 0582327881 |
Internformat
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Datensatz im Suchindex
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adam_text | IMAGE 1
CONTENTS
PREFACE XIIOVERVIEW XV1 INTRODUCTION XVI2 INFORMATION NETWORKS XVII3
PROTEIN INFORMATION RESOURCES XVII4 GENOME INFORMATION RESOURCES XVII5
DNA SEQUENCE ANALYSIS XVIII6 PAIRWISE ALIGNMENT TECHNIQUES XVIII7
MULTIPLE SEQUENCE ALIGNMENT XVIII8 SECONDARY DATABASE SEARCHING XVIII9
BUILDING A SEQUENCE SEARCH PROTOCOL XIX10 ANALYSIS PACKAGES XIX
INTRODUCTION 1 1.1 INTRODUCTION 11.2 THE DAWN OF SEQUENCING 11.3 WHAT IS
BIOINFORMATICS? 21.4 THE BIOLOGICAL SEQUENCE/STRUCTURE DEFICIT 31.5
GENOME PROJECTS 41.6 STATUS OF THE HUMAN GENOME PROJECT 61.7 WHY IS
BIOINFORMATICS IMPORTANT? 61.8 PATTERN RECOGNITION AND PREDICTION 71.9
THE FOLDING PROBLEM 91.10 THE ROLE OF CHAPERONES 101.11 SEQUENCE
ANALYSIS 101.12 HOMOLOGY AND ANALOGY 121.13 THE DEVIL IS IN THE DETAIL
131.14 SUMMARY 161.15 FURTHER READING 16
IMAGE 2
2 INFORMATION NETWORKS 19
2.1 INTRODUCTION 19
2.2 WHAT IS THE INTERNET? 19
2.3 HOW DO COMPUTERS FIND EACH OTHER? 19
2.4 FACILITIES USED ON THE INTERNET 20
2.5 WHAT IS THE WORLD WIDE WEB? 21
2.6 WEB BROWSERS 21
2.7 HTTP, HTML AND URLS 24
2.8 THE EUROPEAN MOLECULAR BIOLOGY NETWORK - EMBNET 24 2.9 THE NATIONAL
CENTER FOR BIOTECHNOLOGY INFORMATION- NCBI 30 2.10 VIRTUAL TOURISM 31
2.11 SUMMARY 33
2.12 FURTHER READING 33
2.12 WEB ADDRESSES 34
3 PROTEIN INFORMATION RESOURCES 35
3.1 INTRODUCTION 35
3.2 BIOLOGICAL DATABASES 35
3.3 PRIMARY SEQUENCE DATABASES 36
3.4 COMPOSITE PROTEIN SEQUENCE DATABASES 43
3.5 SECONDARY DATABASES 45
3.6 COMPOSITE PROTEIN PATTERN DATABASES 62
3.7 STRUCTURE CLASSIFICATION DATABASES 62
3.8 SUMMARY 65
3.9 FURTHER READING 66
3.10 WEB ADDRESSES 67
4 GENOME INFORMATION RESOURCES 69
4.1 INTRODUCTION 69
4.2 DNA SEQUENCE DATABASES 69
4.3 SPECIALISED GENOMIC RESOURCES 75
4.4 SUMMARY 78
4.5 FURTHER READING 78
4.6 WEB ADDRESSES 80
5 DNA SEQUENCE ANALYSIS 81
5.1 INTRODUCTION 81
5.2 WHY ANALYSE DNA? 81
5.3 GENE STRUCTURE AND DNA SEQUENCES 82
5.4 FEATURES OF DNA SEQUENCE ANALYSIS 85
5.5 ISSUES IN THE INTERPRETATION OF EST SEARCHES 89
5.6 TWO APPROACHES TO GENE HUNTING 93
5.7 THE EXPRESSION PROFILE OF A CELL 94
5.8 CDNA LIBRARIES AND ESTS 95
5.9 DIFFERENT APPROACHES TO EST ANALYSIS 96
5.10 EFFECTS OF EST DATA ON DNA DATABASES 100
IMAGE 3
5.11 A PRACTICAL EXAMPLE OF EST ANALYSIS 103
5.12 SUMMARY 106
5.13 FURTHER READING 107
6 PAIRWISE ALIGNMENT TECHNIQUES 108
6.1 INTRODUCTION 108
6.2 DATABASE SEARCHING 108
6.3 ALPHABETS AND COMPLEXITY 109
6.4 ALGORITHMS AND PROGRAMS 109
6.5 COMPARING TWO SEQUENCES - A SIMPLE CASE 109
6.6 SUB-SEQUENCES 110
6.7 IDENTITY AND SIMILARITY 111
6.8 THEDOTPLOT 116
6.9 LOCAL AND GLOBAL SIMILARITY 119
6.10 GLOBAL ALIGNMENT: THE NEEDLEMAN AND WUNSCH ALGORITHM 119 6.11 LOCAL
ALIGNMENT: THE SMITH-WATERMAN ALGORITHM 122
6.12 DYNAMIC PROGRAMMING 125
6.13 PAIRWISE DATABASE SEARCHING 125
6.14 SUMMARY 130
6.15 FURTHER READING 131
7 MULTIPLE SEQUENCE ALIGNMENT 132
7.1 INTRODUCTION 132
7.2 THE GOAL OF MULTIPLE SEQUENCE ALIGNMENT 132
7.3 MULTIPLE SEQUENCE ALIGNMENT: A DEFINITION 133
7.4 THE CONSENSUS 134
7.5 COMPUTATIONAL COMPLEXITY 134
7.6 MANUAL METHODS 135
7.7 SIMULTANEOUS METHODS 136
7.8 PROGRESSIVE METHODS 136
7.9 DATABASES OF MULTIPLE ALIGNMENTS 137
7.10 SEARCHING DATABASES WITH MULTIPLE ALIGNMENTS 141
7.11 SUMMARY 142
7.12 FURTHER READING 143
8 SECONDARY DATABASE SEARCHING 145
8.1 INTRODUCTION 145
8.2 WHY BOTHER WITH SECONDARY DATABASE SEARCHES? 145
8.3 WHAT S IN A SECONDARY DATABASE? 146
8.4 SUMMARY 161
8.5 FURTHER READING 162
9 BUILDING A SEQUENCE SEARCH PROTOCOL 163
9.1 INTRODUCTION 163
9.2 A PRACTICAL APPROACH 163
IMAGE 4
9.3 WHEN TO BELIEVE A RESULT 178
9.4 STRUCTURAL AND FUNCTIONAL INTERPRETATION 179
9.5 SUMMARY 184
9.6 FURTHER READING 184
185 185 185 188 188 189 192 193 194
197 198 198
199 211
10 ANALYSIS PACKAGES 10.1 10.2 10.3 10.4 10.5 10.6 10.7 10.8 10.9 10.10
10.11
INTRODUCTION WHAT S IN AN ANALYSIS PACKAGE? COMMERCIAL DATABASES
COMMERCIAL SOFTWARE
COMPREHENSIVE PACKAGES PACKAGES SPECIALISING IN DNA ANALYSIS INTRANET
PACKAGES INTERNET PACKAGES
SUMMARY FURTHER READING WEB ADDRESSES
GLOSSARY INDEX
FURTHER INFORMATION FOR USE WITH THIS BOOK CAN BE ACCESSED VIA A LINK ON
THE PUBLISHER S WEB SITE AT HTTP://WWW.BOOKSITES.NET. THE WEB SITE
OFFERS AN INTERACTIVE BIOINFORMATICS PRACTICAL THAT AIMS TO GIVE A
FLAVOUR OF PROTEIN SEQUENCE ANALYSIS. THE PRACTICAL BEGINS WITH AN
UNKNOWN DNA FRAGMENT, WHICH THE USER IS INVITED TO IDENTIFY AND
CHARACTERISE VIA SEARCHES OF SEQUENCE, PATTERN AND FOLD CLASSIFICATION
RESOURCES. CHAPTER 9 OF THE BOOK IS DEVOTED TO A WORKED EXAMPLE THROUGH
THIS SEQUENCE SEARCH
PROTOCOL. SOME OF THE SUPPORTING THEORY, AND AN UP-TO-DATE LIST OF WEB
LINKS, ARE ALSO SUPPLIED IN THE PRACTICAL, LEADING TO A TIGHT COUPLING
OF BOOK- AND WEB-BASED MATERIALS. WE WOULD ENCOURAGE READERS TO USE THE
WEB SITE REGULARLY.
|
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author | Attwood, Teresa K. Parry-Smith, David J. |
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dewey-search | 574.87 572.80285 |
dewey-sort | 3574.87 |
dewey-tens | 570 - Biology |
discipline | Biologie Informatik |
edition | 1. publ. |
format | Book |
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spelling | Attwood, Teresa K. Verfasser (DE-588)156768216 aut Introduction to bioinformatics Teresa K. Attwood and David J. Parry-Smith 1. publ. Harlow [u.a.] Prentice Hall 1999 XX, 218 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cell and molecular biology in action series Bio-informatica gtt Datenverarbeitung Molecular biology Data processing Molekulare Bioinformatik (DE-588)4531334-9 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Information (DE-588)4026899-8 gnd rswk-swf Bioinformatik (DE-588)4611085-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bioinformatik (DE-588)4611085-9 s DE-604 Molekulare Bioinformatik (DE-588)4531334-9 s Molekularbiologie (DE-588)4039983-7 s Information (DE-588)4026899-8 s 1\p DE-604 Parry-Smith, David J. Verfasser aut SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008673582&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Attwood, Teresa K. Parry-Smith, David J. Introduction to bioinformatics Bio-informatica gtt Datenverarbeitung Molecular biology Data processing Molekulare Bioinformatik (DE-588)4531334-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Information (DE-588)4026899-8 gnd Bioinformatik (DE-588)4611085-9 gnd |
subject_GND | (DE-588)4531334-9 (DE-588)4039983-7 (DE-588)4026899-8 (DE-588)4611085-9 (DE-588)4143413-4 |
title | Introduction to bioinformatics |
title_auth | Introduction to bioinformatics |
title_exact_search | Introduction to bioinformatics |
title_full | Introduction to bioinformatics Teresa K. Attwood and David J. Parry-Smith |
title_fullStr | Introduction to bioinformatics Teresa K. Attwood and David J. Parry-Smith |
title_full_unstemmed | Introduction to bioinformatics Teresa K. Attwood and David J. Parry-Smith |
title_short | Introduction to bioinformatics |
title_sort | introduction to bioinformatics |
topic | Bio-informatica gtt Datenverarbeitung Molecular biology Data processing Molekulare Bioinformatik (DE-588)4531334-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Information (DE-588)4026899-8 gnd Bioinformatik (DE-588)4611085-9 gnd |
topic_facet | Bio-informatica Datenverarbeitung Molecular biology Data processing Molekulare Bioinformatik Molekularbiologie Information Bioinformatik Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008673582&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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