Signaling networks and cell cycle control: the molecular basis of cancer and other diseases
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2000
|
| Schriftenreihe: | Cancer drug discovery and development
5 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 578 S. |
| ISBN: | 089603710X |
Internformat
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| 100 | 1 | |a Gutkind, J. Silvio |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Signaling networks and cell cycle control |b the molecular basis of cancer and other diseases |c ed. by J. Silvio Gutkind |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2000 | |
| 300 | |a XIV, 578 S. | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 1 | |a Cancer drug discovery and development |v 5 | |
| 650 | 7 | |a Celgroei |2 gtt | |
| 650 | 7 | |a Membranen |2 gtt | |
| 650 | 7 | |a Receptoren |2 gtt | |
| 650 | 7 | |a Regelmechanismen |2 gtt | |
| 650 | 7 | |a Transductie |2 gtt | |
| 650 | 4 | |a Cell Cycle |x physiology | |
| 650 | 4 | |a Cell cycle | |
| 650 | 4 | |a Cellular control mechanisms | |
| 650 | 4 | |a Cellular signal transduction | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Neoplasms |x physiopathology | |
| 650 | 4 | |a Pathology, Molecular | |
| 650 | 4 | |a Receptors, Cell Surface | |
| 650 | 4 | |a Signal Transduction |x physiology | |
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| 650 | 0 | 7 | |a Signaltransduktion |0 (DE-588)4318717-1 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1804127387898609664 |
|---|---|
| adam_text | Contents
13 Signaling Pathways Controlled by Rho Family GTP Binding
Proteins 231
Marc Symons
14 PI3 Kinases: Role in Signal Transduction 247
David A. Fruman and Lewis C. Cantley
15 PI3K Related Kinases: Roles in Cell Cycle Regulation
and DNA Damage Responses 267
Randal S. Tibbetts and Robert T. Abraham
16 Integrative Signaling Through c Abl: A Tyrosine Kinase
with Nuclear and Cytoplasmic Functions 303
Jean Y. J. Wang
17 Src: A Model for Regulation of Intracellular Signaling
Molecules 325
Pamela L. Schwartzberg
18 Inhibitors of Protein Kinase C and Related Receptors
for the Lipophilic Second Messenger sn l,2 Diacylglycerol.. 347
Peter M. Blumberg, Peter Acs, Dipak K. Bhattacharyya,
and Patricia S. Lorenzo
19 Reactive Oxygen Species in Proliferative Signaling 365
Toren Finkel and Daniel M. Sullivan
20 Sphingolipid Metabolites in Signal Transduction 379
Sarah Spiegel and Sheldon Milstien
21 The Jak/Stat Signaling Cascade:
Its Role in the Biological Effects of Interferons 393
Andrew C. Lamer and Andrew Keightley
22 Regulation of Cell Growth and Death by p53 411
Kevin M. Ryan and Karen H. Vousden
23 Regulation of NF kB Function: Novel Molecular Targets
for Pharmacological Intervention 429
Frank Mercurio and Anthony M. Manning
24 Using Protein—Interaction Domains to Manipulate Signaling
Pathways 439
Bruce J. Mayer
25 Protein Tyrosine Kinase Inhibitors as Novel Therapeutic
Agents 453
Alexander Levitzki
26 A Pharmacological Approach to the MAP Kinase Cascade 467
David T. Dudley and Alan R. Saltiel
27 Specific Inhibitors of p38 MAP Kinase 483
Peter R. Young
28 Farnesyltransferase Inhibitors: Anti Ras or Anticancer Drugs? 501
Adrienne D. Cox and Channing J. Der
Contents
Preface v
Contributors xi
1 Integrin Signaling 1
Kenneth M. Yamada and Erik H. J. Danen
2 Signal Transduction Through Tyrosine Kinase Growth Factor
Receptors 27
Paolo Fedi and Stuart A. Aaronson
3 Signaling from TGF 0 Receptors 39
Anita B. Roberts, Mark P. de Caestecker,
and Robert J. Lechleider
4 The Wnt Signal Transduction Pathway 53
Grant D. Barish and Bart O. Williams
5 Signaling from G Protein Coupled Receptors to the Nucleus 83
Shigetomo Fukuhara, Maria Julia Marinissen,
Mario Chiariello, and J. Silvio Gutkind
6 Proximal Events in T Cell Activation 99
Joanne Sloan Lancaster and Lawrence E. Samelson
7 Signal Transduction from the High Affinity IgE Receptor 113
Reuben P. Siraganian
8 Signaling Through Fas (CD95, APO 1) and Related Death
Receptors 135
Richard M. Siegel, David A. Martin, Felicita Hornung,
Erastus C. Dudley, Lixin Zheng, and Michael J. Lenardo
9 Signal Transduction to the Nucleus by MAP Kinase 153
Roger J. Davis
10 The Regulation of MAP Kinase Pathways by MAP Kinase
Phosphatases 165
Kathleen Kelly and Yanfang Chu
11 Control of MAPK Signaling by Ste20 and Ste 11 Like
Kinases 183
Gary R. Fanger, Thomas K. Schlesinger, and Gary L. Johnson
12 Ras Signaling and Transformation 213
Geoffrey J. Clark, John P. O Bryan, and Channing J. Der
vii
Contents ix
29 Targeted p53 Gene Therapy Mediated Radiosensitization
and Chemosensitization 519
Esther H. Chang, Liang Xu, and Kathleen F. Pirollo
30 Treatment of p53 Deficient Cancers by Adenovirus
ElB Region Mutants: From Basic Research to the Clinic 537
David H. Kirn
31 The Cell Cycle Inhibitor p27 as a Prognostic Marker
in Human Tumors and a Novel Target for Therapeutic
Intervention 545
Michele Pagano and Katya Ravid
32 Chemical Cyclin Dependent Kinase Inhibitors:
Therapeutic Implications 557
Edward A. Sausville and Adrian M. Senderowicz
Index 568
|
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| isbn | 089603710X |
| language | English |
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| series | Cancer drug discovery and development |
| series2 | Cancer drug discovery and development |
| spelling | Gutkind, J. Silvio Verfasser aut Signaling networks and cell cycle control the molecular basis of cancer and other diseases ed. by J. Silvio Gutkind Totowa, NJ Humana Press 2000 XIV, 578 S. txt rdacontent n rdamedia nc rdacarrier Cancer drug discovery and development 5 Celgroei gtt Membranen gtt Receptoren gtt Regelmechanismen gtt Transductie gtt Cell Cycle physiology Cell cycle Cellular control mechanisms Cellular signal transduction Drug Design Neoplasms physiopathology Pathology, Molecular Receptors, Cell Surface Signal Transduction physiology Zellzyklus (DE-588)4129960-7 gnd rswk-swf Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Molekularpathologie (DE-588)4170396-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Signaltransduktion (DE-588)4318717-1 s Zellzyklus (DE-588)4129960-7 s Molekularpathologie (DE-588)4170396-0 s DE-604 Cancer drug discovery and development 5 (DE-604)BV011340435 5 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008649888&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gutkind, J. Silvio Signaling networks and cell cycle control the molecular basis of cancer and other diseases Cancer drug discovery and development Celgroei gtt Membranen gtt Receptoren gtt Regelmechanismen gtt Transductie gtt Cell Cycle physiology Cell cycle Cellular control mechanisms Cellular signal transduction Drug Design Neoplasms physiopathology Pathology, Molecular Receptors, Cell Surface Signal Transduction physiology Zellzyklus (DE-588)4129960-7 gnd Signaltransduktion (DE-588)4318717-1 gnd Molekularpathologie (DE-588)4170396-0 gnd |
| subject_GND | (DE-588)4129960-7 (DE-588)4318717-1 (DE-588)4170396-0 (DE-588)4143413-4 |
| title | Signaling networks and cell cycle control the molecular basis of cancer and other diseases |
| title_auth | Signaling networks and cell cycle control the molecular basis of cancer and other diseases |
| title_exact_search | Signaling networks and cell cycle control the molecular basis of cancer and other diseases |
| title_full | Signaling networks and cell cycle control the molecular basis of cancer and other diseases ed. by J. Silvio Gutkind |
| title_fullStr | Signaling networks and cell cycle control the molecular basis of cancer and other diseases ed. by J. Silvio Gutkind |
| title_full_unstemmed | Signaling networks and cell cycle control the molecular basis of cancer and other diseases ed. by J. Silvio Gutkind |
| title_short | Signaling networks and cell cycle control |
| title_sort | signaling networks and cell cycle control the molecular basis of cancer and other diseases |
| title_sub | the molecular basis of cancer and other diseases |
| topic | Celgroei gtt Membranen gtt Receptoren gtt Regelmechanismen gtt Transductie gtt Cell Cycle physiology Cell cycle Cellular control mechanisms Cellular signal transduction Drug Design Neoplasms physiopathology Pathology, Molecular Receptors, Cell Surface Signal Transduction physiology Zellzyklus (DE-588)4129960-7 gnd Signaltransduktion (DE-588)4318717-1 gnd Molekularpathologie (DE-588)4170396-0 gnd |
| topic_facet | Celgroei Membranen Receptoren Regelmechanismen Transductie Cell Cycle physiology Cell cycle Cellular control mechanisms Cellular signal transduction Drug Design Neoplasms physiopathology Pathology, Molecular Receptors, Cell Surface Signal Transduction physiology Zellzyklus Signaltransduktion Molekularpathologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008649888&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV011340435 |
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