Resolving the antibiotic paradox: progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan]
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Kluwer
1998
|
| Schriftenreihe: | Advances in experimental medicine and biology
456 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 293 S. Ill., graph. Darst. |
| ISBN: | 0306460394 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804127339934646272 |
|---|---|
| adam_text | RESOLVING THE ANTIBIOTIC PARADOX PROGRESS IN UNDERSTANDING DRUG
RESISTANCE AND DEVELOPMENT OF NEW ANTIBIOTICS EDITED BY BARRY P. ROSEN
AND SHAHRIAR MOBASHERY WAYNE STATE UNIVERSITY DETROIT, MICHIGAN KLUWER
ACADEMIC / PLENUM PUBLISHERS NEW YORK, BOSTON, DORDRECHT, LONDON, MOSCOW
CONTENTS 1. ANTIBIOTIC RESISTANCE: THE BIG PICTURE 1 DIDIER MAZEL AND
JULIAN DAVIES 2. CLINICAL IMPACT OF ANTIBIOTIC RESISTANCE 7 STEPHEN A.
LERNER 3. REVERSING TETRACYCLINE RESISTANCE: A RENAISSANCE FOR THE
TETRACYCLINE FAMILY OF ANTIBIOTICS 17 STUART B. LEVY AND MARK NELSON 4.
AMINOGLYCOSIDE ANTIBIOTICS: STRUCTURES, FUNCTIONS, AND RESISTANCE 27
GERARD D. WRIGHT, ALBERT M. BERGHUIS, AND SHAHRIAR MOBASHERY 5. HOW
P-LACTAMASES HAVE DRIVEN PHARMACEUTICAL DRUG DISCOVERY: FROM MECHANISTIC
KNOWLEDGE TO CLINICAL CIRCUMVENTION 71 KAREN BUSH AND SHAHRIAR MOBASHERY
6. ANTIFOLATE RESISTANCE MECHANISMS FROM BACTERIA TO CANCER CELLS WITH
EMPHASIS ON PARASITES . * 99 MARC OUELLETTE, ERIC LEBLANC, CHRISTOPH
KIINDIG, AND BARBARA PAPADOPOULOU 7. RESISTANCE TO ANTITUBERCULAR DRUGS
115 LUIZ A. BASSO AND JOHN S. BLANCHARD 8. STRUCTURE AND FUNCTION OF
MULTIDRUG TRANSPORTERS 145 HENDRIK W. VAN VEEN AND WIL N. KONINGS 9.
METALLOID RESISTANCE MECHANISMS 159 RITA MUKHOPADHYAY, JIAXIN LI,
HIRANMOY BHATTACHARJEE, AND BARRY P. ROSEN 10. THE IMPACT OF BACTERIAL
GENOMICS ON ANTIBACTERIAL DISCOVERY 183 DAVID J. C. KNOWLES AND FRANK
KING 11. PEPTIDOGLYCAN BIOSYNTHESIS: UNEXPLOITED ANTIBACTERIAL TARGETS
WITHIN A FAMILIAR PATHWAY 197 KENNY K. WONG AND DAVID L. POMPLIANO X
CONTENTS 12. DESIGN, SYNTHESIS, AND EVALUATION OF NOVEL OXAZOLIDINONE
ANTIBACTERIAL AGENTS ACTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA 219
MICHAEL R. BARBACHYN, STEVEN J. BRICKNER, ROBERT C. GADWOOD, STUART A.
GARMON, KEVIN C. GREGA, DOUGLAS K. HUTCHINSON, KIYOTAKA MUNESADA, ROBERT
J. REISCHER, MIKIO TANIGUCHI, LISA M. THOMASCO, DANA S. TOOPS, HIROMI
YAMADA, CHARLES W. FORD, AND GARY E. ZURENKO 13. CONCEPT, DESIGN, AND
PRECLINICAL EVALUATION OF QUINOLONYL LACTAM ANTIBACTERIALS 239 PAUL M.
HERSHBERGER AND THOMAS P. DEMUTH, JR 14. BACTERIAL TWO-COMPONENT
SIGNALLING AS A THERAPEUTIC TARGET IN DRUG DESIGN: INHIBITION OF NRII BY
THE DIPHENOLIC METHANES (BISPHENOLS) 269 JOHN M. DOMAGALA, DIANE ALESSI,
MAXWELL CUMMINGS, STEPHEN GRACHECK, LIREN HUANG, MICHAEL HUBAND, GREGG
JOHNSON, ERIC OLSON, MARTIN SHAPIRO, RAJESHWAR SINGH, YUNTAO SONG, RUTH
VAN BOGELEN, DEAN VO, AND SARA WOLD INDEX 287
|
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| spelling | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] ed. by Barry P. Rosen ... New York [u.a.] Kluwer 1998 X, 293 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in experimental medicine and biology 456 Arzneimittelresistenz (DE-588)4143180-7 gnd rswk-swf Antibiotikum (DE-588)4002257-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1997 Detroit Mich. gnd-content Antibiotikum (DE-588)4002257-2 s Arzneimittelresistenz (DE-588)4143180-7 s DE-604 Rosen, Barry P. Sonstige oth Advances in experimental medicine and biology 456 (DE-604)BV000003102 456 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008617015&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] Advances in experimental medicine and biology Arzneimittelresistenz (DE-588)4143180-7 gnd Antibiotikum (DE-588)4002257-2 gnd |
| subject_GND | (DE-588)4143180-7 (DE-588)4002257-2 (DE-588)1071861417 |
| title | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] |
| title_auth | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] |
| title_exact_search | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] |
| title_full | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] ed. by Barry P. Rosen ... |
| title_fullStr | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] ed. by Barry P. Rosen ... |
| title_full_unstemmed | Resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] ed. by Barry P. Rosen ... |
| title_short | Resolving the antibiotic paradox |
| title_sort | resolving the antibiotic paradox progress in understanding drug resistance and development of new antibiotics proceedings of the symposium on resolving the antibiotic paradox progress in drug design and resistance held may 29 1997 at wayne state university detroit michigan |
| title_sub | progress in understanding drug resistance and development of new antibiotics ; [proceedings of the Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance, held May 29, 1997, at Wayne State University, Detroit, Michigan] |
| topic | Arzneimittelresistenz (DE-588)4143180-7 gnd Antibiotikum (DE-588)4002257-2 gnd |
| topic_facet | Arzneimittelresistenz Antibiotikum Konferenzschrift 1997 Detroit Mich. |
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