Methyl tertiary butyl ether:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Geneva
World Health Organization
1998
|
| Schriftenreihe: | Environmental health criteria
206 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 199 S. Ill., graph. Darst. |
| ISBN: | 924157206X |
Internformat
MARC
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| 100 | 1 | |a Gillner, M. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Methyl tertiary butyl ether |c first draft prepared by M. Gillner. With contributions from A.-S. Nihlén |
| 246 | 1 | 3 | |a Methyl tertiary-butyl ether |
| 246 | 1 | 3 | |a Methyl tertiary-butyl ether |
| 264 | 1 | |a Geneva |b World Health Organization |c 1998 | |
| 300 | |a XIX, 199 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Environmental health criteria |v 206 | |
| 650 | 7 | |a Arbeidshygiëne |2 gtt | |
| 650 | 7 | |a Biodegradatie |2 gtt | |
| 650 | 4 | |a Butyl méthyl éther - Aspect de l'environnement | |
| 650 | 4 | |a Butyl méthyl éther - Effets physiologiques | |
| 650 | 4 | |a Butyl méthyl éther - Sécurité - Mesures | |
| 650 | 4 | |a Butyl méthyl éther - Toxicologie | |
| 650 | 7 | |a Fysische eigenschappen |2 gtt | |
| 650 | 7 | |a Gevaarlijke stoffen |2 gtt | |
| 650 | 7 | |a Gezondheid |2 gtt | |
| 650 | 7 | |a Industriële productie |2 gtt | |
| 650 | 7 | |a Methyl tertiary butyl ether |2 gtt | |
| 650 | 7 | |a Milieu |2 gtt | |
| 650 | 4 | |a Umwelt | |
| 650 | 4 | |a Butyl methyl ether |x Environmental aspects | |
| 650 | 4 | |a Butyl methyl ether |x Pharmacokinetics | |
| 650 | 4 | |a Butyl methyl ether |x Toxicology | |
| 650 | 4 | |a Environmental Exposure | |
| 650 | 4 | |a Environmental Health | |
| 650 | 4 | |a Environmental health | |
| 650 | 4 | |a Methyl Ethers |x adverse effects | |
| 650 | 4 | |a Methyl Ethers |x pharmacokinetics | |
| 650 | 4 | |a Methyl Ethers |x toxicity | |
| 650 | 4 | |a Occupational Exposure | |
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| 650 | 0 | 7 | |a Toxikologie |0 (DE-588)4060538-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Butylmethylether |g tertiär- |0 (DE-588)4279820-6 |2 gnd |9 rswk-swf |
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| 830 | 0 | |a Environmental health criteria |v 206 |w (DE-604)BV000011459 |9 206 | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-008585424 | ||
Datensatz im Suchindex
| _version_ | 1804127293851828224 |
|---|---|
| adam_text | CONTENTS
ENVIRONMENTAL HEALTH CRITERIA FOR
METHYL TERTIARY BUTfL ETHER
PREAMBLE ix
ABBREVIATIONS xviii
1. SUMMARY 1
1.1 Identity, physical and chemical properties,
analytical methods 1
1.2 Sources of human and environmental exposure 1
1.3 Environmental transport, distribution
and transformation 2
1.4 Environmental levels and human exposure 2
1.5 Kinetics and metabolism 5
1.6 Effects on laboratory animals and in vitro systems 5
1.7 Effects on humans 7
1.8 Effects on other organisms in the laboratory and
field 8
1.9 Evaluation of human health risks and effects on the
environment 8
2. IDENTITY, PHYSICAL AND CHEMICAL
PROPERTIES, ANALYTICAL METHODS 10
2.1 Identity 10
2.2 Physical and chemical properties 11
2.3 Conversion factors 11
2.4 Analytical methods 11
2.4.1 Procedures 11
2.4.1.1 Air 11
2.4.1.2 Soil, water and sediment 15
2.4.1.3 Gasoline 16
2.4.1.4 Biological samples 17
3. SOURCES OF HUMAN AND ENVIRONMENTAL
EXPOSURE 19
3.1 Natural occurrence 19
3.2 Anthropogenic sources 19
3.2.1 Production levels and processes 19
3.2.2 Uses 20
3.2.3 Sources and releases to the environment 22
3.2.3.1 Industrial releases 22
3.2.3.2 Storage tank release 22
3.2.3.3 Engine emissions from on road
and off road vehicles and
recreational boats 23
3.3 Other pertinent information 24
4. ENVIRONMENTAL BEHAVIOUR AND FATE 26
4.1 Transport and distribution between media 26
4.1.1 Air 26
4.1.2 Water 26
4.1.3 Soil 29
4.1.4 Multimedia 29
4.2 Bioconcentration 29
4.3 Biodegradation and transformation 30
4.3.1 Aerobic conditions 30
4.3.2 Anaerobic conditions 33
4.4 Abiotic degradation 35
4.4.1 Air 35
4.4.1.1 Photolysis 35
4.4.1.2 Hydrolysis 35
4.4.1.3 Photooxidation 35
4.4.2 Natural waters 37
4.4.3 MTBE half life ranges in environmental
compartments 37
4.5 Ozone forming potential 37
4.6 Remediation 38
5. ENVIRONMENTAL LEVELS AND HUMAN
EXPOSURE 39
5.1 Environmental levels 39
5.1.1 Exposure 39
5.1.1.1 Levels in ambient air and
various microenvironments 40
5.1.1.2 Dermal exposure 66
5.1.1.3 Estimation of total personal
exposure 66
5.1.1.4 Other pollutants 66
5.2 Occupational exposure 67
5.2.1 Industrial operations manufacturing
and blending 67
5.2.2 Transportation 72
5.2.3 Service station attendants and garage
mechanics 73
5.2.4 Occupational exposure limit values 74
5.3 Exposure via water 75
5.3.1 Snow and precipitation 75
5.3.2 Surface water 75
5.3.3 Groundwater 77
5.3.4 Drinking water 78
5.4 Soil and sediment 79
5.5 Biota 79
6. KINETICS AND METABOLISM IN HUMANS AND
LABORATORY ANIMALS 80
6.1 Human data 80
6.1.1 Controlled human studies 80
6.1.2 Exposure to oxygenated gasoline 93
6.2 Animal studies 93
6.3 In vitro studies 96
6.4 Physiologically based pharmacokinetic modelling 99
7. EFFECTS ON LABORATORY MAMMALS AND
IN VITRO SYSTEMS 100
7.1 Single exposure 100
7.2 Skin, eye and respiratory irritation;
skin sensitization 106
7.2.1 Skin irritation 106
7.2.2 Eye irritation 106
7.2.3 Respiratory tract irritation 107
7.2.4 Skin sensitization 108
7.3 Neurotoxicity 108
7.4 Short term repeated dose studies 109
7.4.1 Oral studies 109
7.4.2 Inhalation studies 112
7.4.3 Intraperitoneal administration 115
7.5 Neurotoxicity studies 115
7.6 Reproductive and developmental toxicity 116
7.6.1 Reproductive toxicity 121
7.6.2 Developmental toxicity 122
7.7 Mutagenicity and related end points 123
7.8 Carcinogenicity 128
7.8.1 Initiation promotion protocol 138
7.9 Metabolites of MTBE 139
7.10 Mode of action 139
7.10.1 Kidney tumours 139
7.10.2 Liver tumours 139
8. EFFECTS ON HUMANS 143
81 Population studies 143
82 Controlled studies 146
8.3 Subpopulations at special risk 148
84 Special studies 148
8.4.1 Organoleptic properties 148
8.4.2 Immunological effects 149
9. EFFECTS ON OTHER ORGANISMS IN THE
LABORATORY AND FIELD 150
9.1 Laboratory experiments 150
9.1.1 Algae 150
9.1.2 Aquatic animal species 150
9.2 Field experiments 153
10. EVALUATION OF HUMAN HEALTH RISKS AND
EFFECTS ON THE ENVIRONMENT 154
10.1 Evaluation of human health risks 154
10.1.1 Exposure 154
10.1.2 Human health effects 155
10.2 Evaluation of effects on the environment 160
11. RECOMMENDATIONS 162
REFERENCES 163
RESUME 180
RESUMEN 190
|
| any_adam_object | 1 |
| author | Gillner, M. Nihlén, A.-S |
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| id | DE-604.BV012636837 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:31:03Z |
| institution | BVB |
| isbn | 924157206X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008585424 |
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| owner_facet | DE-12 DE-Er8 |
| physical | XIX, 199 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | World Health Organization |
| record_format | marc |
| series | Environmental health criteria |
| series2 | Environmental health criteria |
| spelling | Gillner, M. Verfasser aut Methyl tertiary butyl ether first draft prepared by M. Gillner. With contributions from A.-S. Nihlén Methyl tertiary-butyl ether Geneva World Health Organization 1998 XIX, 199 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Environmental health criteria 206 Arbeidshygiëne gtt Biodegradatie gtt Butyl méthyl éther - Aspect de l'environnement Butyl méthyl éther - Effets physiologiques Butyl méthyl éther - Sécurité - Mesures Butyl méthyl éther - Toxicologie Fysische eigenschappen gtt Gevaarlijke stoffen gtt Gezondheid gtt Industriële productie gtt Methyl tertiary butyl ether gtt Milieu gtt Umwelt Butyl methyl ether Environmental aspects Butyl methyl ether Pharmacokinetics Butyl methyl ether Toxicology Environmental Exposure Environmental Health Environmental health Methyl Ethers adverse effects Methyl Ethers pharmacokinetics Methyl Ethers toxicity Occupational Exposure Umwelttoxikologie (DE-588)4121813-9 gnd rswk-swf Toxikologie (DE-588)4060538-3 gnd rswk-swf Butylmethylether tertiär- (DE-588)4279820-6 gnd rswk-swf Butylmethylether tertiär- (DE-588)4279820-6 s Umwelttoxikologie (DE-588)4121813-9 s DE-604 Toxikologie (DE-588)4060538-3 s Nihlén, A.-S. Verfasser aut Environmental health criteria 206 (DE-604)BV000011459 206 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008585424&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gillner, M. Nihlén, A.-S Methyl tertiary butyl ether Environmental health criteria Arbeidshygiëne gtt Biodegradatie gtt Butyl méthyl éther - Aspect de l'environnement Butyl méthyl éther - Effets physiologiques Butyl méthyl éther - Sécurité - Mesures Butyl méthyl éther - Toxicologie Fysische eigenschappen gtt Gevaarlijke stoffen gtt Gezondheid gtt Industriële productie gtt Methyl tertiary butyl ether gtt Milieu gtt Umwelt Butyl methyl ether Environmental aspects Butyl methyl ether Pharmacokinetics Butyl methyl ether Toxicology Environmental Exposure Environmental Health Environmental health Methyl Ethers adverse effects Methyl Ethers pharmacokinetics Methyl Ethers toxicity Occupational Exposure Umwelttoxikologie (DE-588)4121813-9 gnd Toxikologie (DE-588)4060538-3 gnd Butylmethylether tertiär- (DE-588)4279820-6 gnd |
| subject_GND | (DE-588)4121813-9 (DE-588)4060538-3 (DE-588)4279820-6 |
| title | Methyl tertiary butyl ether |
| title_alt | Methyl tertiary-butyl ether |
| title_auth | Methyl tertiary butyl ether |
| title_exact_search | Methyl tertiary butyl ether |
| title_full | Methyl tertiary butyl ether first draft prepared by M. Gillner. With contributions from A.-S. Nihlén |
| title_fullStr | Methyl tertiary butyl ether first draft prepared by M. Gillner. With contributions from A.-S. Nihlén |
| title_full_unstemmed | Methyl tertiary butyl ether first draft prepared by M. Gillner. With contributions from A.-S. Nihlén |
| title_short | Methyl tertiary butyl ether |
| title_sort | methyl tertiary butyl ether |
| topic | Arbeidshygiëne gtt Biodegradatie gtt Butyl méthyl éther - Aspect de l'environnement Butyl méthyl éther - Effets physiologiques Butyl méthyl éther - Sécurité - Mesures Butyl méthyl éther - Toxicologie Fysische eigenschappen gtt Gevaarlijke stoffen gtt Gezondheid gtt Industriële productie gtt Methyl tertiary butyl ether gtt Milieu gtt Umwelt Butyl methyl ether Environmental aspects Butyl methyl ether Pharmacokinetics Butyl methyl ether Toxicology Environmental Exposure Environmental Health Environmental health Methyl Ethers adverse effects Methyl Ethers pharmacokinetics Methyl Ethers toxicity Occupational Exposure Umwelttoxikologie (DE-588)4121813-9 gnd Toxikologie (DE-588)4060538-3 gnd Butylmethylether tertiär- (DE-588)4279820-6 gnd |
| topic_facet | Arbeidshygiëne Biodegradatie Butyl méthyl éther - Aspect de l'environnement Butyl méthyl éther - Effets physiologiques Butyl méthyl éther - Sécurité - Mesures Butyl méthyl éther - Toxicologie Fysische eigenschappen Gevaarlijke stoffen Gezondheid Industriële productie Methyl tertiary butyl ether Milieu Umwelt Butyl methyl ether Environmental aspects Butyl methyl ether Pharmacokinetics Butyl methyl ether Toxicology Environmental Exposure Environmental Health Environmental health Methyl Ethers adverse effects Methyl Ethers pharmacokinetics Methyl Ethers toxicity Occupational Exposure Umwelttoxikologie Toxikologie Butylmethylether tertiär- |
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