Molecular and applied aspects of oxidative drug metabolizing enzymes: [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey]
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Kluwer Acad., Plenum Press
1999
|
| Schriftenreihe: | NATO: [NATO ASI series / A]
303 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 294 S. Ill., graph. Darst., Kt. |
| ISBN: | 0306460483 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS
1. The Fate of Xenobiotics in the Body: Enzymes of Metabolism 1
John B. Schenkman
2. Protein Protein Interactions in the P450 Monooxygenase System 21
John B. Schenkman, Ingela Jansson, Gary Davis, Paul P. Tamburini,
Zhongqing Lu, Zhe Zhang, and James F. Rusling
3. Structures of Mitochondrial P450 System Proteins 41
Israel Hanukoglu
4. Biochemical Aspects of Flavin Containing Monooxygenases (FMOs) 55
Ernest Hodgson, Nathan J. Cherrington, Richard M. Philpot, and
Randy L. Rose
5. Expression and Regulation of Flavin Containing Monooxygenases 71
Richard M. Philpot, Christine P. Biagini, Geraldine T. Carver, Lila H. Overby,
M. Keith Wyatt, and Kiyoshi Itagaki
6. Correlations between in Vivo and in Vitro Studies in Human Drug Metabolism . . 81
Michel Eichelbaum
7. Pharmacogenetics: Polymorphisms in Xenobiotic Metabolism 91
Frank J. Gonzalez
8. Clinical Aspects of Polymorphic Drug Metabolism in Human ¦ Ill
Michel Eichelbaum
9. Genetic Polymorphisms of Cytochromes P450 1 Al and 2E1 and of Glutathione
S Transferase Ml and Cancer Susceptibility in the Human 127
Minro Watanabe
10. Cytochrome P450 Isoforms: Insecticide Metabolism in Insects and Mammals
and Role in Insecticide Resistance 145
Ernest Hodgson, R. Michael Roe, Joyce E. Goldstein, Siming Liu,
Scott C. Coleman, and Randy L. Rose
vii
viii Contents
11. Inhibitors of CYP51 as Antifungal Agents and Resistance to Azole Antifungals 157
Steven L. Kelly, David C. Lamb, and Diane E. Kelly
12. The Role of Oxidative Drug Metabolizing Enzymes in Liver and Lung Specific
Toxicity 173
Richard M. Philpot
13. Importance of Drug Metabolism in Drug Discovery and Development 183
Rodolfo Gasser
14. Aflatoxin Biotransformation and Toxicology 195
David L. Eaton
15. Role of Individual Enzymes in the Control of Genotoxic Metabolites 211
Franz Oesch and Michael Arand
16. Enhancement of the Mutagenicity of Ethylene Oxide and Several Directly
Acting Mutagens by Human Erythrocytes and Its Reduction by
Xenobiotic Interaction 221
Jan G. Hengstler, Jochen Walz, Rani Kiibel, Tri Truong, Jiirgen Fuchs,
Albrecht Seidel, Michael Arand, and Franz Oesch
17. Cytochrome P4501A1 (Cyp 1A1) and Associated MFO Activities in Fish as an
Indicator of Pollution with Special Reference to Izmir Bay 247
Emel Arinc and Alaattin Sen
18. Cyp 1A Concentrations as an Indicator of Exposure of Fish to Pulp Mill
Effluents 259
R. F. Addison and J. Y. Wilson
19. The Biochemistry and Physiology of Prostacyclin and Thromboxane Synthase 271
Volker Ullrich
20. Cell Engineering of the Rat and Human Cysteine Conjugate Beta Lyase Genes
and Applications to Nephrotoxicity Assessment 283
G. Gordon Gibson, Peter S. Goldfarb, Laurie J. King, Ian Kitchen,
Nick Plant, Claire Scholfield, and Helen Harries
Index 293
|
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| bvnumber | BV012617558 |
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| genre_facet | Konferenzschrift 31.08.1997-11.09.1997 Antalya |
| id | DE-604.BV012617558 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:30:42Z |
| institution | BVB |
| isbn | 0306460483 |
| language | English |
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| physical | 294 S. Ill., graph. Darst., Kt. |
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| spelling | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] ed. by Emel Arınç ... New York [u.a.] Kluwer Acad., Plenum Press 1999 294 S. Ill., graph. Darst., Kt. txt rdacontent n rdamedia nc rdacarrier NATO: [NATO ASI series / A] 303 Xenobiotikum (DE-588)4193155-5 gnd rswk-swf Cytochrom P-450 (DE-588)4148705-9 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Monooxygenasen (DE-588)4170475-7 gnd rswk-swf Biotransformation (DE-588)4006908-4 gnd rswk-swf Enzymatische Regulation (DE-588)4136839-3 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 31.08.1997-11.09.1997 Antalya gnd-content Xenobiotikum (DE-588)4193155-5 s Biotransformation (DE-588)4006908-4 s Enzymatische Regulation (DE-588)4136839-3 s Molekularbiologie (DE-588)4039983-7 s DE-604 Cytochrom P-450 (DE-588)4148705-9 s Monooxygenasen (DE-588)4170475-7 s Arınç, Emel Sonstige oth A] NATO: [NATO ASI series 303 (DE-604)BV000902941 303 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008570571&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] Xenobiotikum (DE-588)4193155-5 gnd Cytochrom P-450 (DE-588)4148705-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Monooxygenasen (DE-588)4170475-7 gnd Biotransformation (DE-588)4006908-4 gnd Enzymatische Regulation (DE-588)4136839-3 gnd |
| subject_GND | (DE-588)4193155-5 (DE-588)4148705-9 (DE-588)4039983-7 (DE-588)4170475-7 (DE-588)4006908-4 (DE-588)4136839-3 (DE-588)1071861417 |
| title | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] |
| title_auth | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] |
| title_exact_search | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] |
| title_full | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] ed. by Emel Arınç ... |
| title_fullStr | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] ed. by Emel Arınç ... |
| title_full_unstemmed | Molecular and applied aspects of oxidative drug metabolizing enzymes [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] ed. by Emel Arınç ... |
| title_short | Molecular and applied aspects of oxidative drug metabolizing enzymes |
| title_sort | molecular and applied aspects of oxidative drug metabolizing enzymes proceedings of a nato acvanced study institute on molecular and applied aspects of oxidative drug metabolizing enzymes held august 31 september 11 1997 in antalya turkey |
| title_sub | [proceedings of a NATO Acvanced Study Institute on Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes, held August 31 - September 11, 1997, in Antalya, Turkey] |
| topic | Xenobiotikum (DE-588)4193155-5 gnd Cytochrom P-450 (DE-588)4148705-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Monooxygenasen (DE-588)4170475-7 gnd Biotransformation (DE-588)4006908-4 gnd Enzymatische Regulation (DE-588)4136839-3 gnd |
| topic_facet | Xenobiotikum Cytochrom P-450 Molekularbiologie Monooxygenasen Biotransformation Enzymatische Regulation Konferenzschrift 31.08.1997-11.09.1997 Antalya |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008570571&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000902941 |
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