The elusive magic bullet: the search for the perfect drug
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
1999
|
| Ausgabe: | 1. publ. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 209 S. Ill. |
| ISBN: | 0198500939 0198500920 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV012551899 | ||
| 003 | DE-604 | ||
| 005 | 20050201 | ||
| 007 | t | ||
| 008 | 990507s1999 a||| |||| 00||| eng d | ||
| 020 | |a 0198500939 |9 0-19-850093-9 | ||
| 020 | |a 0198500920 |9 0-19-850092-0 | ||
| 035 | |a (OCoLC)40395543 | ||
| 035 | |a (DE-599)BVBBV012551899 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-12 | ||
| 050 | 0 | |a RM301.25 | |
| 082 | 0 | |a 610.904 |2 21 | |
| 082 | 0 | |a 615/.1/09 |2 21 | |
| 100 | 1 | |a Mann, John |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a The elusive magic bullet |b the search for the perfect drug |c John Mann |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 1999 | |
| 300 | |a X, 209 S. |b Ill. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 648 | 7 | |a Geschichte |2 gnd |9 rswk-swf | |
| 650 | 7 | |a Geneesmiddelen |2 gtt | |
| 650 | 4 | |a Médicaments - Recherche - Histoire | |
| 650 | 4 | |a Pharmacologie - Histoire | |
| 650 | 7 | |a Ziektebestrijding |2 gtt | |
| 650 | 4 | |a Geschichte | |
| 650 | 4 | |a Drugs |x Research |x History | |
| 650 | 4 | |a Pharmaceutical Preparations |x history | |
| 650 | 4 | |a Pharmacology |x History | |
| 650 | 4 | |a Pharmacology |x history | |
| 650 | 4 | |a Research |x history | |
| 650 | 0 | 7 | |a Antimikrobieller Wirkstoff |0 (DE-588)4142688-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Cytostatikum |0 (DE-588)4068347-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Arzneimittelforschung |0 (DE-588)4003120-2 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Antimikrobieller Wirkstoff |0 (DE-588)4142688-5 |D s |
| 689 | 0 | 1 | |a Arzneimittelforschung |0 (DE-588)4003120-2 |D s |
| 689 | 0 | 2 | |a Geschichte |A z |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Cytostatikum |0 (DE-588)4068347-3 |D s |
| 689 | 1 | 1 | |a Arzneimittelforschung |0 (DE-588)4003120-2 |D s |
| 689 | 1 | 2 | |a Geschichte |A z |
| 689 | 1 | |5 DE-604 | |
| 856 | 4 | 2 | |m GBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008522069&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-008522069 | ||
Datensatz im Suchindex
| _version_ | 1804127197648125952 |
|---|---|
| adam_text | THE ELUSIVE MAGIC BULLET THE SEARCH FOR THE PERFECT DRUG JOHN MANN
OXFORD UNIVERSITY PRESS CONTENTS 1 INTRODUCTION 1 2 FIGHTING BACTERIA 14
THE BLACK DEATH 14 MIASMATA, ANIMALCULES, AND MAL ARIA 18 ANTISEPTICS 23
FROM DYES TO SULPHONAMIDES: THE FIRST ANTIBACTERIALS 33 PENICILLINS:
EARLY IDEAS OF ANTIBIOSIS 36 PENICILLINS: FLEMING S SERENDIPITOUS
DISCOVERY 39 CHAIN AND FLOREY AND THE PENICILLIN PRODUCTION LINE 47
SEMI-SYNTHETIC PENICILLINS AND THE GROWING PROBLEM OF RESISTANCE 54 THE
MOULD THAT GREW ON SEWAGE: EVOLUTION OF THE CEPHALOSPORINS 57 THE MODE
OF ACTION OF PENICILLINS AND CEPHALOSPORINS 59 THE WHITE PLAGUE AND ITS
TREATMENT 61 MORE TREASURES FROM STREPTOMYCES 68 THE RISE OF THE
SUPERBUGS 72 3 ANTIVIRAL TREATMENTS 77 INTRODUCTION 77 WHAT IS A
VIRUS? 78 ANTIBODIES: NATURE S MAGIC BULLETS 81 SMALLPOX 81 RABIES 92
POLIO 94 GENE TECHNOLOGY 96 COUGHS AND COLDS AND INFLUENZA 98 INFLUENZA:
THE DISEASE 98 INFLUENZA: THE TREATMENTS 104 THE COMMON COLD 105 HERPES:
COLD SORES AND CHICKEN POX 107 AIDS: HISTORY OF THE DISEASE 111 AIDS:
PREVENTION AND TREATMENT 118 HAEMORRHAGIC FEVER VIRUSES 124 X THE
ELUSIVE MAGIC BULLET 4 CANCER AND ANTICANCER DRUGS 129 AETIOLOGY 131
CANCER CHEMOTHERAPY 144 FROM POISON GAS TO PLATINUM DRUGS 145 BEATING
LEUKAEMIA 152 OTHER ANTIMETABOLITES 157 PERIWINKLES, MAY-APPLES, AND YEW
TREES: ANTICANCER DRUGS FROM PLANTS 159 MICROORGANISMS ALSO PRODUCE
ANTITUMOUR AGENTS 170 ANTITUMOUR DRUGS FROM THE SEA 174 TURNING OFF
HORMONAL INFLUENCES 175 BREAST CANCER 179 PROSTATE CANCER 181 BIOLOGICAL
WARFARE: INVENTING REAL MAGIC BULLETS 184 PREVENTION IS BETTER THAN CURE
191 5 MAGIC BULLETS: STILL ELUSIVE AFTER ALL THESE YEARS 193 FURTHER
READING 198 INDEX 205
|
| any_adam_object | 1 |
| author | Mann, John |
| author_facet | Mann, John |
| author_role | aut |
| author_sort | Mann, John |
| author_variant | j m jm |
| building | Verbundindex |
| bvnumber | BV012551899 |
| callnumber-first | R - Medicine |
| callnumber-label | RM301 |
| callnumber-raw | RM301.25 |
| callnumber-search | RM301.25 |
| callnumber-sort | RM 3301.25 |
| callnumber-subject | RM - Therapeutics and Pharmacology |
| ctrlnum | (OCoLC)40395543 (DE-599)BVBBV012551899 |
| dewey-full | 610.904 615/.1/09 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health 615 - Pharmacology and therapeutics |
| dewey-raw | 610.904 615/.1/09 |
| dewey-search | 610.904 615/.1/09 |
| dewey-sort | 3610.904 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1. publ. |
| era | Geschichte gnd |
| era_facet | Geschichte |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02110nam a2200589 c 4500</leader><controlfield tag="001">BV012551899</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20050201 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">990507s1999 a||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0198500939</subfield><subfield code="9">0-19-850093-9</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0198500920</subfield><subfield code="9">0-19-850092-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)40395543</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV012551899</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RM301.25</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610.904</subfield><subfield code="2">21</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615/.1/09</subfield><subfield code="2">21</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Mann, John</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">The elusive magic bullet</subfield><subfield code="b">the search for the perfect drug</subfield><subfield code="c">John Mann</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1. publ.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford [u.a.]</subfield><subfield code="b">Oxford Univ. Press</subfield><subfield code="c">1999</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">X, 209 S.</subfield><subfield code="b">Ill.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="648" ind1=" " ind2="7"><subfield code="a">Geschichte</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Geneesmiddelen</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Médicaments - Recherche - Histoire</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacologie - Histoire</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Ziektebestrijding</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Geschichte</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs</subfield><subfield code="x">Research</subfield><subfield code="x">History</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmaceutical Preparations</subfield><subfield code="x">history</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology</subfield><subfield code="x">History</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology</subfield><subfield code="x">history</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Research</subfield><subfield code="x">history</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Antimikrobieller Wirkstoff</subfield><subfield code="0">(DE-588)4142688-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Cytostatikum</subfield><subfield code="0">(DE-588)4068347-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arzneimittelforschung</subfield><subfield code="0">(DE-588)4003120-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Antimikrobieller Wirkstoff</subfield><subfield code="0">(DE-588)4142688-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Arzneimittelforschung</subfield><subfield code="0">(DE-588)4003120-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Geschichte</subfield><subfield code="A">z</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Cytostatikum</subfield><subfield code="0">(DE-588)4068347-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Arzneimittelforschung</subfield><subfield code="0">(DE-588)4003120-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Geschichte</subfield><subfield code="A">z</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">GBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008522069&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-008522069</subfield></datafield></record></collection> |
| id | DE-604.BV012551899 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:29:31Z |
| institution | BVB |
| isbn | 0198500939 0198500920 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008522069 |
| oclc_num | 40395543 |
| open_access_boolean | |
| owner | DE-12 |
| owner_facet | DE-12 |
| physical | X, 209 S. Ill. |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Oxford Univ. Press |
| record_format | marc |
| spelling | Mann, John Verfasser aut The elusive magic bullet the search for the perfect drug John Mann 1. publ. Oxford [u.a.] Oxford Univ. Press 1999 X, 209 S. Ill. txt rdacontent n rdamedia nc rdacarrier Geschichte gnd rswk-swf Geneesmiddelen gtt Médicaments - Recherche - Histoire Pharmacologie - Histoire Ziektebestrijding gtt Geschichte Drugs Research History Pharmaceutical Preparations history Pharmacology History Pharmacology history Research history Antimikrobieller Wirkstoff (DE-588)4142688-5 gnd rswk-swf Cytostatikum (DE-588)4068347-3 gnd rswk-swf Arzneimittelforschung (DE-588)4003120-2 gnd rswk-swf Antimikrobieller Wirkstoff (DE-588)4142688-5 s Arzneimittelforschung (DE-588)4003120-2 s Geschichte z DE-604 Cytostatikum (DE-588)4068347-3 s GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008522069&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mann, John The elusive magic bullet the search for the perfect drug Geneesmiddelen gtt Médicaments - Recherche - Histoire Pharmacologie - Histoire Ziektebestrijding gtt Geschichte Drugs Research History Pharmaceutical Preparations history Pharmacology History Pharmacology history Research history Antimikrobieller Wirkstoff (DE-588)4142688-5 gnd Cytostatikum (DE-588)4068347-3 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| subject_GND | (DE-588)4142688-5 (DE-588)4068347-3 (DE-588)4003120-2 |
| title | The elusive magic bullet the search for the perfect drug |
| title_auth | The elusive magic bullet the search for the perfect drug |
| title_exact_search | The elusive magic bullet the search for the perfect drug |
| title_full | The elusive magic bullet the search for the perfect drug John Mann |
| title_fullStr | The elusive magic bullet the search for the perfect drug John Mann |
| title_full_unstemmed | The elusive magic bullet the search for the perfect drug John Mann |
| title_short | The elusive magic bullet |
| title_sort | the elusive magic bullet the search for the perfect drug |
| title_sub | the search for the perfect drug |
| topic | Geneesmiddelen gtt Médicaments - Recherche - Histoire Pharmacologie - Histoire Ziektebestrijding gtt Geschichte Drugs Research History Pharmaceutical Preparations history Pharmacology History Pharmacology history Research history Antimikrobieller Wirkstoff (DE-588)4142688-5 gnd Cytostatikum (DE-588)4068347-3 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| topic_facet | Geneesmiddelen Médicaments - Recherche - Histoire Pharmacologie - Histoire Ziektebestrijding Geschichte Drugs Research History Pharmaceutical Preparations history Pharmacology History Pharmacology history Research history Antimikrobieller Wirkstoff Cytostatikum Arzneimittelforschung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008522069&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mannjohn theelusivemagicbulletthesearchfortheperfectdrug |