Autoimmune rheumatic disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
1999
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 277 S. Ill., graph. Darst. |
| ISBN: | 0192628836 |
Internformat
MARC
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| 245 | 1 | 0 | |a Autoimmune rheumatic disease |c John Morrow ... |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 1999 | |
| 300 | |a IX, 277 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 4 | |a Autoimmune Diseases | |
| 650 | 4 | |a Autoimmune diseases | |
| 650 | 4 | |a Collagen Diseases | |
| 650 | 4 | |a Rheumatic Diseases | |
| 650 | 4 | |a Rheumatism | |
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| 650 | 0 | 7 | |a Autoaggressionskrankheit |0 (DE-588)4003935-3 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1804127108283236352 |
|---|---|
| adam_text | Contents
1. Introduction: the immune system — order and disorder
Introduction 1
The normal immune response 1
Organization of the lymphoid system 9
The cells of the immune system 9
HLA genes and molecules 14
Immune tolerance 19
The immune system in concert 21
References 23
2. Immunological methodology
Introduction 24
Fundamentals of practical immunology 24
Immunological tests used for evaluation of the autoimmune rheumatic diseases 32
Summary 42
References 42
3. Therapeutic manipulation of the immune system
Introduction 43
Established non selective immunotherapy 44
Non selective therapies under investigation 46
Selective immunotherapy 48
Summary 52
References 52
4. Systematic lupus erythematosus
Introduction 56
Milestones in the history of SLE 56
Definition and classification 57
Epidemiology and natural history 57
Clinical features 58
SLE in children 68
SLE and pregnancy 69
Lupus in other situations 69
Immunogenetics 70
Experimental models of SLE 73
Immunopathology of SLE 76
Cellular dysregulation 76
Management of SLE 91
Summary 96
References 96
vii
viii Contents
5. Rheumatoid arthritis
Introduction 104
Milestones in the history of RA 104
Classification 105
Epidemiology and outcome 105
The clinical picture 106
Clinical assessment of patients 111
Complications and associated disorders 111
Investigations in RA 113
Immunogenetics 116
Animal models 121
Immunopathogenesis of RA 125
Management of RA 131
Summary 139
References 140
6. Sjogren s syndrome
Introduction 147
Milestones in the history of Sjogren s syndrome 147
Classification of Sjogren s syndrome 148
The clinical picture 148
Immunogenetics 157
Experimental models 159
Aetiopathogenesis 161
Treatment 165
Summary 166
References 166
7. Polymyositis
Introduction 170
Milestones in the history of myositis 170
The clinical picture 170
Systemic features 173
Laboratory investigations 176
Aetiology and pathogenesis 183
Immunogenetics 184
Animal models 185
Pathogenic mechanisms 186
Treatment of myositis in adults 189
Summary 190
References 190
8. Scleroderma
Introduction 194
Milestones in the history of scleroderma 194
Clinical features 194
Outcome 205
Immunogenetics 205
Animal models 207
Contents ix
Pathogenesis of scleroderma 209
Treatment 210
Summary 212
References 213
9. Primary anti phospholipid antibody syndrome
Introduction 216
Milestones in the history of APS 216
Clinical features 218
Anti phospholipid antibody syndrome in children 220
Immunogenetics 220
Animal models of APS 222
Immunopathology, including laboratory tests 224
Management of APS 228
Summary 229
References 229
10. Overlap syndromes
Introduction 233
Milestones in the history of overlap syndromes 233
Mixed connective tissue disease 233
tRNA synthetase syndrome 238
Scleroderma/polymyositis overlap 238
SLE/Sjogren s syndrome overlap 239
Rhupus 239
Immunogenetics 239
Summary 239
References 239
11. Vasculitis
Introduction 242
Milestones in the history of systemic vasculitis 242
Systemic vasculitis in humans 243
Diagnostic criteria for individual diseases 243
Epidemiology 245
The clinical picture 245
Vasculitis in children 253
Investigation of vasculitis 255
Aetiopathogenesis 255
Animal models 258
Immunogenetics 259
Prognosis and mortality 262
Management and treatment 263
Summary 265
References 255
Index 271
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| indexdate | 2024-07-09T18:28:06Z |
| institution | BVB |
| isbn | 0192628836 |
| language | English |
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| physical | IX, 277 S. Ill., graph. Darst. |
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| spelling | Autoimmune rheumatic disease John Morrow ... 2. ed. Oxford [u.a.] Oxford Univ. Press 1999 IX, 277 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Autoimmune Diseases Autoimmune diseases Collagen Diseases Rheumatic Diseases Rheumatism Rheumatismus (DE-588)4049836-0 gnd rswk-swf Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Autoaggressionskrankheit (DE-588)4003935-3 s Rheumatismus (DE-588)4049836-0 s DE-604 Morrow, John Sonstige (DE-588)127611096 oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008461525&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Autoimmune rheumatic disease Autoimmune Diseases Autoimmune diseases Collagen Diseases Rheumatic Diseases Rheumatism Rheumatismus (DE-588)4049836-0 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd |
| subject_GND | (DE-588)4049836-0 (DE-588)4003935-3 |
| title | Autoimmune rheumatic disease |
| title_auth | Autoimmune rheumatic disease |
| title_exact_search | Autoimmune rheumatic disease |
| title_full | Autoimmune rheumatic disease John Morrow ... |
| title_fullStr | Autoimmune rheumatic disease John Morrow ... |
| title_full_unstemmed | Autoimmune rheumatic disease John Morrow ... |
| title_short | Autoimmune rheumatic disease |
| title_sort | autoimmune rheumatic disease |
| topic | Autoimmune Diseases Autoimmune diseases Collagen Diseases Rheumatic Diseases Rheumatism Rheumatismus (DE-588)4049836-0 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd |
| topic_facet | Autoimmune Diseases Autoimmune diseases Collagen Diseases Rheumatic Diseases Rheumatism Rheumatismus Autoaggressionskrankheit |
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