Thoracic manifestations of the systemic autoimmune diseases:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1998
|
| Schriftenreihe: | Clinics in chest medicine
19,4 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII S., S. 573 - 836 zahlr. Ill., graph. Darst. |
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| 245 | 1 | 0 | |a Thoracic manifestations of the systemic autoimmune diseases |c Richard A. Matthay guest ed. |
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| 650 | 2 | |a Maladies cardiovasculaires | |
| 650 | 4 | |a Autoimmune Diseases |x complications | |
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THORACIC MANIFESTATIONS OF THE SYSTEMIC AUTOIMMUNE DISEASES
CONTENTS
Preface xi
Richard A. Matthay
Radiologic Manifestations of the Systemic Autoimmune Diseases 573
Steven L. Primack and Nestor L. Miiller
Advances in thoracic imaging during the past two decades, such as CT
scans and MR imaging, have enhanced our understanding of the pleuro
pulmonary abnormalities that develop in the systemic autoimmune dis¬
eases. In this article, the thoracic radiologic manifestations of several
connective tissue diseases (systemic lupus erythematosus, rheumatoid ar¬
thritis, Sjogren's syndrome, polymyositis/dermatomyositis, progressive
systemic sclerosis, and anklyosing spondylitis), two granulomatous vascu
litides, (Wegener's Granulomatosis and Churg Strauss syndrome), and
antiglomerular basement membrane disease are reviewed.
Pulmonary Pathology in Patients with Systemic Autoimmune
Diseases 587
Thomas V. Colby
The well recognized pathology of the collagen vascular diseases is re¬
viewed along with pathologic findings in systemic vasculitides that com¬
monly involve the lung. The pathology of alveolar hemorrhage syndromes
is also reviewed.
Antinuclear Antibody Testing in Systemic Autoimmune Disease 613
Janine Evans
This article discusses the use and interpretation of antinuclear antibody
(ANA) testing in connective tissue diseases. Methods of ANA detection
are discussed and analyzed in detail as is the role of ANAs in systemic
lupus, scleroderma, and polymyositis, connective tissue diseases with
prominent pulmonary involvement.
CLINICS IN CHEST MEDICINE VOLUME 19 • NUMBER 4 • DECEMBER 1998 vii
Antineutrophil Cytoplasmic Antibodies as Markers for Systemic
Autoimmune Disease 627
Robert J. Homer
Antineutrophil cytoplasmic antibodies (ANCA) have been associated with
systemic vasculitis for almost 15 years. Significant advances in our under¬
standing of the ANCA phenomenon have occurred with recognition of
broadening the spectrum of diseases associated with ANCA, identification
of specific antigens recognized by ANCA, and development of antigen
specific assays for clinical use. Nevertheless problems continue for the
chest physician in interpretation of this test. Although antigen specific
testing improves overall performance of the test, accurate assessment
of pretest probability of disease is still important for effective use of
ANCA testing.
Pulmonary Manifestations of Systemic Lupus Erythematosus 641
Susan Murin, Herbert P. Wiedemann, and Richard A. Matthay
Systemic lupus erythematosus (SLE) is an autoimmune disease that pri¬
marily affects young women. The respiratory system is more commonly
involved in SLE than in any other collagen vascular disease. SLE may
affect virtually all components of the respiratory system, including the
upper airway, lung parenchyma, pulmonary vasculature, pleura, and res¬
piratory muscles. Respiratory system involvement ranges from sympto¬
matic to fulminant and life threatening. This article reviews the pulmonary
manifestations of SLE, including drug induced SLE.
Pulmonary Manifestations of Rheumatoid Arthritis 667
Lynn T. Tanoue
Rheumatoid arthritis (RA) is the most common of the classic connective
tissue diseases. Its manifestations in the chest are varied as the pleura, lung
parenchyma, airways, and pulmonary vasculature can all be involved. The
approach to a patient with RA and respiratory complaints, radiographic
findings, or physiologic abnormalities requires a broad understanding of
these manifestations. Moreover, the potential for therapy related toxicity
adds further complexity to the pulmonary evaluation of these patients.
Pulmonary Manifestations of Sjogren's Syndrome 687
Hilary C. Cain, Paul W. Noble, and Richard A. Matthay
Sjogren's syndrome is one of the most common systemic rheumatic dis¬
eases. Pulmonary disease is prevalent in Sjogren's syndrome; respiratory
manifestations include chronic cough, obstructive airways disease, pulmo¬
nary lymphoma, and interstitial lung disease that may progress to severe
pulmonary fibrosis.
The Lung in Polymyositis 701
Marvin I. Schwarz
Polymyositis is associated with a variety of pulmonary manifestations that
may complicate an established case, occur simultaneously with the muscle
manifestations, or precede the muscle disease. Included are respiratory
muscle involvement, aspiration syndromes, and a variety of interstitial
lung reactions.
Manifestations of Scleroderma Pulmonary Disease 713
Omar A. Minai, Raed A. Dweik, and Alejandro C. Arroliga
Scleroderma is a multisystem disease of unknown cause characterized by
synthesis and deposition of excessive extracellular matrix and vascular
Viii CONTENTS
obliteration. Pulmonary involvement is a significant cause of morbidity
and mortality. This article gives an overview of the pulmonary manifesta¬
tions of scleroderma and discusses diagnostic and therapeutic options.
Respiratory Complications in Mixed Connective Tissue Disease 733
Udaya B. S. Prakash
The term mixed connective tissue disease is used to identify the patients with
combined clinical features of systemic lupus erythematosus, scleroderma
or progressive systemic sclerosis, and polymyositis dermatomyositis. A
prerequisite for the diagnosis of mixed connective tissue disease is the
presence, in the serum, of high titers of antibodies against uridine rich
RNA small nuclear ribonucleoprotein (snRNP). Respiratory and nonrespi
ratory features of the disease follow those seen in systemic lupus erythe¬
matosus, scleroderma, or progressive systemic sclerosis, and polymyositis
dermatomyositis. Respiratory involvement is observed in 20% to 80% of
patients. Major respiratory manifestations and their incidences described
include interstitial pneumonitis and fibrosis (20% to 65%), pleural effusion
(50%), pleurisy (20%), and pulmonary hypertension (10% to 45%). Other
pulmonary features consist of pulmonary vasculitits, pulmonary thrombo
embolism, aspiration pneumonia, pulmonary hemorrhage, pulmonary
nodules, pulmonary cysts, obstructive airways disease, mediastinal lymph
adenopathy, pulmonary infections, hypoventilatory respiratory failure, and
diaphragmatic dysfunction. Pulmonary hypertension is a serious complica¬
tion; rapid deterioration and death have occurred in spite of corticosteroid
and cytotoxic chemotherapy.
Pulmonary Maifestations of Ankylosing Spondylitis and Relapsing
Polychondritis 747
Teofilo L. Lee Chiong, Jr
Ankylosing spondylitis is a chronic inflammatory disease that affects
chiefly the joints of the axial skeleton. It is a multisystem disease. Several
extra auricular manifestations of ankylosing spondylitis have been de¬
scribed including ocular, cardiovascular, renal, and neurologic complica¬
tions. Pulmonary involvement consists principally of upper lobe fibrocystic
changes and chest wall restriction. Relapsing polychondritis, on the other
hand, is a rare disorder characterized by progressive inflammation and
degeneration of the cartilaginous structures and other connective tissues
throughout the body. Involvement of the respiratory tract is identified in
more than one half of patients with relapsing polychondritis.
Pulmonary Vasculitis 759
Eugene J. Sullivan and Gary S. Hoffman
Pulmonary vascular inflammation may be seen in a variety of primary
lung diseases and in the setting of numerous systemic illnesses. This article
reviews those entities in which pulmonary vasculitis represents a central
feature of the pathologic process (Wegener's granulomatosis, Churg
Strauss syndrome, and pulmonary capillaritis). In addition, features of
pulmonary involvement in other systemic vasculitides (Giant Cell Arteri
tis, Takayasu's Arteritis, and Behget's disease) are described. Finally, gen¬
eral principles for the treatment of vasculitis are reviewed.
Pulmonary Manifestations of Goodpasture's Syndrome:
Antiglomerular Basement Membrane Disease and Related Disorders 777
Joseph A. Ball and K. Randall Young, Jr
Goodpasture's syndrome, or antiglomerular basement membrane disease,
is a disorder in which lungs and kidneys are affected by the binding of
CONTENTS ix
anti GBM antibodies, leading to pulmonary hemorrhage and glomerulone
phritis with rapidly progressive renal insufficiency. Recent advances in the
understanding of disease pathogenesis and diagnosis and treatment have —
significantly improved our ability to recognize the syndrome, distinguish
it from other similar disorders, and offer successful treatment. This article
focuses on the pathogenetic features, clinical manifestations, diagnostic
strategies, and therapeutic principles of anti GBM disease.
Cardiovascular Manifestations of Systemic Autoimmune Diseases 793
Michael J. Longo and Michael S. Remetz
The systemic autoimmune diseases are a protean group of illnesses that
primarily affect the joints, muscles, and connective tissue. All aspects of
the cardiovascular system can be involved with clinical consequences
ranging from asymptomatic abnormalities to serious life threatening con¬
ditions. This article discusses the cardiovascular manifestations of the
systemic autoimmune diseases with particular focus on clinical pathophys
iology and management.
Pulmonary Toxicity of Drugs Used to Treat Systemic Autoimmune
Diseases 809
Daniel Libby and Dorothy A. White
A number of drugs used to treat systemic autoimmune diseases can
cause respiratory complications. These include bronchospasm, noncardiac
pulmonary edema, interstitial pneumonitis and fibrosis, hypersensitivity,
and numerous other disorders. Additionally, some of these drugs increase
the risk of infections, particularly with opportunistic organisms. This arti¬
cle reviews the clinical presentation and mechanism of toxicity of drug
related pulmonary complications.
Cumulative Index 1998 823
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| spelling | Thoracic manifestations of the systemic autoimmune diseases Richard A. Matthay guest ed. Philadelphia [u.a.] Saunders 1998 XII S., S. 573 - 836 zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Clinics in chest medicine 19,4 Auto-immuunziekten gtt Longfunctie gtt Maladies auto-immunes Maladies cardiovasculaires Autoimmune Diseases complications Autoimmune diseases Complications Cardiovascular Diseases Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Brustorgan (DE-588)4194536-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Autoaggressionskrankheit (DE-588)4003935-3 s Brustorgan (DE-588)4194536-0 s Krankheit (DE-588)4032844-2 s DE-604 Matthay, Richard A. Sonstige oth Clinics in chest medicine 19,4 (DE-604)BV000001084 19,4 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008378064&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Thoracic manifestations of the systemic autoimmune diseases Clinics in chest medicine Auto-immuunziekten gtt Longfunctie gtt Maladies auto-immunes Maladies cardiovasculaires Autoimmune Diseases complications Autoimmune diseases Complications Cardiovascular Diseases Autoaggressionskrankheit (DE-588)4003935-3 gnd Krankheit (DE-588)4032844-2 gnd Brustorgan (DE-588)4194536-0 gnd |
| subject_GND | (DE-588)4003935-3 (DE-588)4032844-2 (DE-588)4194536-0 (DE-588)4143413-4 |
| title | Thoracic manifestations of the systemic autoimmune diseases |
| title_auth | Thoracic manifestations of the systemic autoimmune diseases |
| title_exact_search | Thoracic manifestations of the systemic autoimmune diseases |
| title_full | Thoracic manifestations of the systemic autoimmune diseases Richard A. Matthay guest ed. |
| title_fullStr | Thoracic manifestations of the systemic autoimmune diseases Richard A. Matthay guest ed. |
| title_full_unstemmed | Thoracic manifestations of the systemic autoimmune diseases Richard A. Matthay guest ed. |
| title_short | Thoracic manifestations of the systemic autoimmune diseases |
| title_sort | thoracic manifestations of the systemic autoimmune diseases |
| topic | Auto-immuunziekten gtt Longfunctie gtt Maladies auto-immunes Maladies cardiovasculaires Autoimmune Diseases complications Autoimmune diseases Complications Cardiovascular Diseases Autoaggressionskrankheit (DE-588)4003935-3 gnd Krankheit (DE-588)4032844-2 gnd Brustorgan (DE-588)4194536-0 gnd |
| topic_facet | Auto-immuunziekten Longfunctie Maladies auto-immunes Maladies cardiovasculaires Autoimmune Diseases complications Autoimmune diseases Complications Cardiovascular Diseases Autoaggressionskrankheit Krankheit Brustorgan Aufsatzsammlung |
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