The physiology of excitable cells:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge Univ. Press
1998
|
| Ausgabe: | 4. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Hier auch später erschienene, unveränderte Nachdrucke |
| Beschreibung: | XII, 477 S. Ill., graph. Darst. |
| ISBN: | 0521574153 9780521574211 0521574218 |
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| 264 | 1 | |a Cambridge |b Cambridge Univ. Press |c 1998 | |
| 300 | |a XII, 477 S. |b Ill., graph. Darst. | ||
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| 650 | 7 | |a Cells |2 cabt | |
| 650 | 4 | |a Electrophysiology | |
| 650 | 4 | |a Excitable membranes | |
| 650 | 4 | |a Muscle cells | |
| 650 | 4 | |a Neural transmission | |
| 650 | 4 | |a Neurons | |
| 650 | 4 | |a Neurophysiology | |
| 650 | 4 | |a Sensory receptors | |
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Datensatz im Suchindex
| _version_ | 1804126973096624128 |
|---|---|
| adam_text | The physiology of
excitable cells
FOURTH EDITION
David J Aidley
School of Biological Sciences
University of East Anglia Norwich
CAMBRIDGE
UNIVERSITY PRESS
Contents
Preface xi
PARTAFOUNDATIONS1
1 Introduction 3
The biological material 3
Electricity 5
Scientific investigation 6
2 Electrophysiological methods 8
Recording electrodes 8
Electronic amplification 8
The cathode ray oscilloscope 9
Electrical stimulation 10
The voltage clamp technique 10
3 The resting cell membrane 13
Membrane structure 13
Membrane proteins 16
Concentration cells 19
Ionic concentrations in the cytoplasm 20
Active transport of ions 21
Coupled transporter systems 25
The resting potential 26
Chloride movements in muscle 29
The electrogenic nature of the sodium pump 31
PARTBNERVOUSCONDUCTION 33
4 Electrical properties of the nerve axon 35
Action potentials in single axons 35
Electrical stimulation parameters 37
Subthreshold potentials 40
Impedance changes during activity 42
Core-conductor theory 43
The local circuit theory 46
Saltatory conduction in myelinated nerves 49
Compound action potentials 52
5 The ionic basis of nervous conduction 54
The sodium theory
Ionic movements during activity
Contents viii
Voltage clamp experiments 57
Experiments on perfused giant axons 67
Fixed charges and the involvement of calcium
ions 68
Gating currents 70
Electrical excitability in some electric organs 71
6 Voltage-gated channels 76
Voltage-gated sodium channels 76
Molecular biology of the sodium channel 84
Voltage-gated potassium channels 91
Voltage-gated calcium channels 101
PARTCSYNAPTICTRANSMISSION 105
7 Fast synaptic transmission 107
The nature of synaptic transmission 107
Neuromuscular transmission 108
Synaptic transmission in electric organs 118
Fast synaptic excitation in mammalian spinal
motoneurons 120
Postsynaptic inhibition in mammalian spinal
motoneurons 125
8 Neurotransmitter-gated channels 129
Structure of the nicotinic acetylcholine
receptor 129
Permeability and selectivity of the nAChR
channel 137
Kinetics of nAChR channel state changes 140
Pharmacology of the nAChR 145
The 5-hydroxytryptamine-gated channel 145
The GABAa and glycine receptor channels 146
Glutamate receptor channels 149
The P,x ATP receptor channel 153
9 Slow synaptic transmission 154
Slow synaptic potentials 154
Second messengers and G proteins 156
G-protein-linked receptors 161
Muscarinic receptors 164
Catecholamines 165
Some other 7TM receptors for small
molecules 167
Neuropeptide transmitters 169
Gaseous transmitters 171
10 Synthesis, release and fate of neurotransmitters 173
Transmitter release from synaptic vesicles 173
Presynaptic events producing transmitter
release 183
Presynaptic receptors and presynaptic
inhibition 192
Synthesis and packaging of neurotransmitters 193
Non-quantal release of acetylcholine 198
Removal of neurotransmitter from the
synaptic cleft 198
11 Learning-related changes at synapses 201
Simple learning in Aplysia 201
Long-term potentiation in the hippocampus 206
Neurogenetics of fruit fly learning 212
The cellular basis of memory 214
12 Electrotonic transmission and coupling 215
Synapses operating by electrotonic
transmission 215
Gap junction channels 217
An inhibitory synapse operating by electrical
transmission 220
PARTDSENSORYCELLS 223
13 The organization of sensory receptors 225
The variety of sense organs 225
Coding of sensory information 227
Initiation of sensory nerve impulses 228
Further aspects of sensory coding 231
Transmitter-receiver systems 238
Central control of receptors 238
Perception 239
14 Mechanoreceptors 240
The acoustico-lateralis system of vertebrates 240
The mammalian cochlea 248
Mammalian muscle spindles 254
Touch 259
15 Photoreceptors 264
The eye 264
Rhodopsin 268
The absolute threshold 276
Phototransduction 279
Colour vision 291
16 Chemoreceptors 297
Taste mechanism in mammals 297
Olfactory transduction in mammals 301
Chemoreception in insects 307
17 Some other sensory receptors 313
Thermoreceptors 313
Nociceptors and pain 314
Electroreceptors 316
Contents ix
PARTEMUSCLECELLS
18 Mechanics and energetics of muscle
Anatomy
Mechanical properties
Heat production
Chemical change in muscle
19 The contractile mechanism of muscle
The myofibril in 1953
The sliding filament theory
Structure of the contractile machinery
The nature of cross-bridge action
321 20 Activation of muscular contraction 372
Excitation-contraction coupling 372
323 The molecular basis of activation 380
3?3 ,,, 21 Var ie tiesof musc le des ign 383 3 4 ^ Vertebrate skeletal muscles 383
Vertebrate heart muscle 385
Vertebrate smooth muscle 393
336 Arthropod muscles 399
Molluscan and other invertebrate muscles 405 336
References 409
361 Index 469
|
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| author | Aidley, David J. |
| author_facet | Aidley, David J. |
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| author_sort | Aidley, David J. |
| author_variant | d j a dj dja |
| building | Verbundindex |
| bvnumber | BV012346595 |
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| dewey-full | 573.8 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 573 - Specific physiological systems in animals |
| dewey-raw | 573.8 |
| dewey-search | 573.8 |
| dewey-sort | 3573.8 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| edition | 4. ed. |
| format | Book |
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| indexdate | 2024-07-09T18:25:57Z |
| institution | BVB |
| isbn | 0521574153 9780521574211 0521574218 |
| language | English |
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| spelling | Aidley, David J. Verfasser aut The physiology of excitable cells David J. Aidley 4. ed. Cambridge Cambridge Univ. Press 1998 XII, 477 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Hier auch später erschienene, unveränderte Nachdrucke Neurophysiology cabt Cells cabt Electrophysiology Excitable membranes Muscle cells Neural transmission Neurons Neurophysiology Sensory receptors Muskelzelle (DE-588)4127323-0 gnd rswk-swf Sinneszelle (DE-588)4181546-4 gnd rswk-swf Nervenzelle (DE-588)4041649-5 gnd rswk-swf Physiologie (DE-588)4045981-0 gnd rswk-swf Erregungsleitung (DE-588)4135394-8 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf Sinneszelle (DE-588)4181546-4 s Physiologie (DE-588)4045981-0 s DE-604 Muskelzelle (DE-588)4127323-0 s Nervenzelle (DE-588)4041649-5 s Zelle (DE-588)4067537-3 s Erregungsleitung (DE-588)4135394-8 s 1\p DE-604 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008371451&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Aidley, David J. The physiology of excitable cells Neurophysiology cabt Cells cabt Electrophysiology Excitable membranes Muscle cells Neural transmission Neurons Neurophysiology Sensory receptors Muskelzelle (DE-588)4127323-0 gnd Sinneszelle (DE-588)4181546-4 gnd Nervenzelle (DE-588)4041649-5 gnd Physiologie (DE-588)4045981-0 gnd Erregungsleitung (DE-588)4135394-8 gnd Zelle (DE-588)4067537-3 gnd |
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| title | The physiology of excitable cells |
| title_auth | The physiology of excitable cells |
| title_exact_search | The physiology of excitable cells |
| title_full | The physiology of excitable cells David J. Aidley |
| title_fullStr | The physiology of excitable cells David J. Aidley |
| title_full_unstemmed | The physiology of excitable cells David J. Aidley |
| title_short | The physiology of excitable cells |
| title_sort | the physiology of excitable cells |
| topic | Neurophysiology cabt Cells cabt Electrophysiology Excitable membranes Muscle cells Neural transmission Neurons Neurophysiology Sensory receptors Muskelzelle (DE-588)4127323-0 gnd Sinneszelle (DE-588)4181546-4 gnd Nervenzelle (DE-588)4041649-5 gnd Physiologie (DE-588)4045981-0 gnd Erregungsleitung (DE-588)4135394-8 gnd Zelle (DE-588)4067537-3 gnd |
| topic_facet | Neurophysiology Cells Electrophysiology Excitable membranes Muscle cells Neural transmission Neurons Sensory receptors Muskelzelle Sinneszelle Nervenzelle Physiologie Erregungsleitung Zelle |
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