Essentials of nuclear medicine imaging:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1998
|
| Ausgabe: | 4. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVI, 468 S. Ill., graph. Darst. |
| ISBN: | 0721651216 |
Internformat
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| 245 | 1 | 0 | |a Essentials of nuclear medicine imaging |c Fred A. Mettler ; Milton J. Guiberteau |
| 250 | |a 4. ed. | ||
| 264 | 1 | |a Philadelphia [u.a.] |b Saunders |c 1998 | |
| 300 | |a XVI, 468 S. |b Ill., graph. Darst. | ||
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| 650 | 7 | |a Beeldverwerkende diagnostiek |2 gtt | |
| 650 | 4 | |a Imagerie pour le diagnostic | |
| 650 | 7 | |a Nucleaire geneeskunde |2 gtt | |
| 650 | 4 | |a Scintigraphie | |
| 650 | 4 | |a Diagnostic imaging | |
| 650 | 4 | |a Nuclear Medicine | |
| 650 | 4 | |a Radioisotope scanning | |
| 650 | 4 | |a Radionuclide Imaging | |
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Datensatz im Suchindex
| _version_ | 1804126958681849856 |
|---|---|
| adam_text | Con
Chapter 1
RADIOACTIVITY, RADIONUCLIDES,
AND RADIOPHARMACEUTICALS .... 1
BASIC ISOTOPE NOTATION 1
NUCLEAR STABILITY AND DECAY .. 1
RADIONUCLIDE PRODUCTION ... 3
RADIOACTIVE DECAY 4
RADIONUCLIDE GENERATOR
SYSTEMS 5
RADIONUCLIDES 6
Technetium 99m 6
Iodine 7
Xenon 8
Gallium 9
Indium 10
Thallium 10
Positron Emitting
Radionuclides 10
RADIOPHARMACEUTICALS 11
Monoclonal Antibodies 11
Adverse Reactions 16
Investigational
Radiopharmaceuticals 16
RADIATION SPILLS 17
Chapter 2
BASIC INSTRUMENTATION AND
COMPUTERS 19
ANGER OR GAMMA
SCINTILLATION CAMERA 19
Collimator 19
Crystal 23
Photomultiplier Tubes 23
Pulse Height Analyzer 23
Console Controls 24
Resolution 25
Count Rate and Dead Time ... 27
Field Uniformity 27
SPECIALIZED GAMMA
CAMERAS 27
Geiger Mueller Counter 28
Ionization Chambers 28
SODIUM IODIDE WELL
COUNTER 28
SINGLE PROBE COUNTING
SYSTEM 29
DOSE CALIBRATOR 29
COMPUTERS 30
Hardware 31
tents Camera Computer Interface
and Terminal 32
Software 33
Image Acquisition: Memory and
Matrix Size 34
Image Display and Processing .... 34
Filters 35
Operator Interaction 36
Magnetic and Optical Disk
Drives 36
Communications 37
Chapter 3
BASIC QUALITY CONTROL 39
INSTRUMENTATION 39
Dose Calibrator 39
Gamma Cameras 40
RADIOPHARMACY QUALITY
CONTROL 42
Generator and Radionuclide
Purity 43
Radiochemical Labeling 44
Sterility 49
Chapter 4
EMISSION COMPUTED
TOMOGRAPHY 51
SINGLE PHOTON EMISSION
COMPUTED TOMOGRAPHY .... 51
Instrumentation 51
Data Acquisition 52
Tomographic Image
Production 55
Quality Control 57
POSITRON EMISSION
TOMOGRAPHY 59
Chapter 5
APPROACH TO IMAGE
INTERPRETATION 63
OPTIMAL CLINICAL
INTERPRETATION 63
INTERPRETATION ISSUES SPECIFIC
TO NUCLEAR MEDICINE 64
Focal Cold Lesions 64
Generalized Decrease in
Activity 68
Focal Hot Lesions 69
Generalized Increase in
Activity 72
xi
Xii • CONTENTS
FUNCTIONAL AND DYNAMIC
IMAGES 74
APPROACH TO UNKNOWN
CASES 74
Chapter 6
CEREBROVASCULAR SYSTEM 79
RADIONUCLIDE BRAIN
IMAGING 79
Introduction 79
Planar Brain Imaging 79
Radiopharmaceuticals 79
Technique 81
Radionuclide Angiogram 81
Static Images 81
Normal Planar Brain Scan 81
Clinical Applications 81
SPECT Brain Perfusion
Imaging 84
Radiopharmaceuticals 85
Technique 86
Normal SPECT Brain Scan 86
Image Interpretation 87
Clinical Applications 88
PET Imaging 95
Metabolic Brain Imaging 95
Neuroreceptor Imaging 96
CEREBROSPINAL FLUID
IMAGING 96
Radiopharmaceuticals 96
Technique 96
Normal Examination 96
Clinical Applications 97
Communicating Hydrocephalus ... 97
Noncommunicating
Hydrocephalus 98
Cerebrospinal Fluid Leaks 98
Shunt Patency 101
Chapter 7
THYROID, PARATHYROID, AND
SALIVARY GLANDS 105
THYROID IMAGING 105
Radiopharmaceuticals 105
Iodine 131 105
Iodine 123 105
Technetium 99m 105
Dosimetry 106
Iodine Uptake Test 108
Principle and Technique 108
Procedure 108
Factors Affecting Iodine Uptake ... 109
Clinical Considerations 110
Special Tests of Thyroid Function ... 110
Thyroid Gland Imaging 110
Technical Considerations Ill
Normal Images 112
Abnormal Images 112
Ectopic Thyroid Tissue 112
Congenital Organification
Defect 1 10
Thyroid Nodules 113
Multinodular Gland 116
Diffuse Toxic Goiter ...
(Graves Disease) 1 IO
Thyroiditis 117
Thyroid Carcinoma 118
Iodine 131 Therapy in Thyroid
Disease 121
Principle 121
Primary Hyperthyroidism 121
Thyroid Carcinoma 123
PARATHYROID IMAGING 125
SALIVARY GLAND IMAGING 127
Chapter 8
CARDIOVASCULAR SYSTEM 129
ANATOMY AND PHYSIOLOGY .... 129
MYOCARDIAL PERFUSION
IMAGING 131
Principle 131
Choice of
Radiopharmaceuticals 132
THALLIUM EXERCISE
REDISTRIBUTION IMAGING 132
Radiopharmaceutical 132
Physical Characteristics 132
Biokinetics 132
Exercise SPECT Thallium
Imaging Protocol 134
Technique 134
SPECT Image Display and
Manipulation 139
Tomographic Myocardial Slice . nr.
Display 139
Bulls Eye or Polar Map Display .... 1 39
Interpretation of SPECT
Images 139
Normal Appearance, Variants, _
and Artifacts 139
Abnormal Scan 142
Quantitative Image Analysis ... 149
Planar Myocardial Imaging ... 149
Planar Image Interpretation 149
TECHNETIUM MYOCARDIAL
PERFUSION
RADIOPHARMACEUTICALS 149
Isonitriles (Sestamlbi) 151
Diphosphines 153
Q Class Agents 153
Thallium 201 Technetium 99m
Sestamibi Imaging 153
Gated SPECT Imaging 153
ALTERNATIVES TO EXERCISE:
PHARMACOLOGIC STRESS 154
Dipyridamole Myocardial
Perfusion Imaging 154
Technique 155
Image Interpretation 155
Adenosine Stress Imaging 155
Dobutamine Stress Imaging ... 156
CLINICAL APPLICATIONS OF
MYOCARDIAL PERFUSION
IMAGING 156
Coronary Artery Disease 156
Diagnosis of Coronary Artery
Disease 156
Hemodynamic Significance of
Coronary Stenosis 15/
Collateral Coronary Vessels 157
Evaluation of Myocardial
Revascularization 15o
Risk Stratification in Coronary
Artery Disease 158
Risk Stratification After
Myocardial Infarction I OO
Myocardial Viability 160
Evaluation of Acute Chest Pain .... 161
Preoperative Risk Assessment 161
Noncoronary Disease States ... 162
Valvular Lesions I Oz
Left Bundle Branch Block 163
Hypertensive Myocardial
Hypertrophy 104
RADIONUCLIDE IMAGING OF
CARDIAC FUNCTION 164
Computer Methods 164
Qualitative Data Display 165
Functional Images 165
Quantitative Data Display 167
First Transit Studies of
Cardiac Function 170
Principle 170
Radiopharmaceutical 170
Technique 170
Image Interpretation 171
contents • xiii
Equilibrium or Blood Pool
Radionuclide
Ventriculography 172
Principle 172
Radiopharmaceutical 172
Technique 172
Image Interpretation 1 74
Qualitative Data 1 75
Quantitative Data 1 75
Clinical Applications 1 76
INFARCT AVID
(PYROPHOSPHATE)
IMAGING 179
Technique 180
Timing of the Examination 1 80
Scan Interpretation 180
Diffuse Uptake 180
Focal Uptake 181
Persistent Uptake 181
Sensitivity and Specificity 182
Clinical Applications 182
Diagnosis of Acute Myocardial
Infarction 182
OTHER INFARCT AVID
RADIOPHARMACEUTICALS 182
POSITRON EMISSION
TOMOGRAPHY 182
Chapter 9
RESPIRATORY SYSTEM 191
ANATOMY AND PHYSIOLOGY .... 191
RADIOPHARMACEUTICALS 192
Perfusion Imaging Agents 192
Ventilation Imaging Agents 193
Radioactive Inert Gases 193
Radiolabeled Aerosols 194
TECHNIQUE 195
Perfusion Imaging 195
Ventilation Imaging 195
Xenon 133 Imaging 195
Technetium 99m Aerosol
Imaging 197
NORMAL LUNG SCAN 197
Perfusion Scan 197
Ventilation Scan 198
CLINICAL APPLICATIONS 200
Pulmonary Emboli 200
Diagnostic Principle 201
Basic Concepts 201
Analysis of Images 204
Lung Scan Interpretation 211
Optimizing Interpretation 214
xiv • CONTENTS
Pulmonary Arteriography 220
Lung Scan Follow up of
Pulmonary Emboli 220
Nonembolic Diseases 220
Chronic Obstructive Pulmonary
Disease 220
Mucous Plugs 22 I
Asthma, Bronchiectasis, and
Bronchitis 224
Lung Neoplasms 226
Inflammatory Disease 227
Cardiovascular Abnormalities 228
DEEP VENOUS IMAGING AND
THROMBUS DETECTION 231
Chapter 10
GASTROINTESTINAL TRACT 237
COLLOIDAL LIVER SPLEEN
IMAGING 237
Radiopharmaceuticals 237
Technique 237
Planar Imaging 237
Single Photon Emission
Computed Tomography 239
Normal Scan 239
Abnormal Scan 240
Alcoholic Liver Disease 242
Diffuse and Infiltrative Disorders 243
Metastatic Disease 246
Primary Liver Neoplasms 247
Miscellaneous Focal Lesions 248
SPLENIC IMAGING 249
Normal Scan 249
Abnormal Scan 251
Focal Lesions 251
Splenomegaly 252
Trauma 252
Nonvisualization of the Spleen 252
GASTROINTESTINAL BLEEDING .... 256
Technique 257
Interpretation 258
MECKEL S DIVERTICULUM 259
HEPATOBILIARY IMAGING 260
Radiopharmaceuticals 260
Technique 262
Normal Scan 263
Clinical Settings 263
Acute Cholecystitis 263
Chronic Cholecystitis 267
Biliary Obstruction 267
Post traumatic and Postsurgical
Biliary Scans 272
Biliary Atresia and Neonatal _
Hepatitis 274
GASTROESOPHAGEAL
FUNCTION 274
ESOPHAGEAL TRANSIT 275
Radiopharmaceuticals 275
Technique 275
Normal and Abnormal
Studies 276
GASTROESOPHAGEAL REFLUX
STUDIES 276
Radiopharmaceuticals 277
Technique 277
Normal and Abnormal
Studies 277
GASTRIC EMPTYING 277
Radiopharmaceuticals 277
Technique 278
Normal and Abnormal
Studies 278
SCHILLING TEST 278
ABDOMINAL SHUNT
EVALUATION 281
Chapter 11
SKELETAL SYSTEM 285
ANATOMY AND PHYSIOLOGY .... 285
RADIOPHARMACEUTICALS 285
TECHNIQUE 286
NORMAL SCAN 287
CLINICAL APPLICATIONS 291
Metastatic Disease 291
Malignant Bone Tumors 296
Benign Osseous Neoplasms ... 299
Soft Tissue Uptake 299
Trauma 311
Osteomyelitis, Cellulitis, and
Septic Arthritis 320
Benign Non neoplastic
Disease 326
BONE MARROW SCANNING 326
THERAPY OF PAINFUL OSSEOUS
METASTASES 326
BONE MINERAL
MEASUREMENTS 331
Chapter 12
GENITOURINARY SYSTEM 335
PHYSIOLOGY 335
RADIOPHARMACEUTICALS 335
Glomerular Filtration Agents ... 335
Tubular Secretion Agents 336
Renal Cortical Agents 337
RADIONUCLIDE RENAL
EVALUATION 337
Functional Renal Imaging 337
Renography 340
Quantitation of Renal
Function 342
CLINICAL APPLICATIONS 343
Diffuse Renal Disease 343
Vascular Abnormalities 343
Obstructive Uropathy 343
Pediatric Hydronephrosis 349
Angiotensin Converting
Enzyme Inhibitor
Renography 349
Acute Pyelonephritis 354
Renal Masses 355
Radionuclide Cystography 356
Renal Transplant Evaluation ... 356
SCROTAL IMAGING 361
Testicular Torsion 362
Testicular Appendage
Torsion 362
Acute Epididymitis 363
Miscellaneous Scrotal
Pathology 363
ADRENAL GLAND IMAGING 363
Adrenal Cortical (NP 59)
Imaging 363
Clinical Applications 365
Adrenal Medullary Imaging ... 365
Chapter 13
NEOPLASM IMAGING 369
GALLIUM 67 IMAGING 369
Physical Characteristics 369
Biologic Behavior 369
Mechanism of Localization in
Neoplasm 370
Technique 370
Normal Scan 371
Clinical Applications 372
THALLIUM 201 CHLORIDE
IMAGING 375
TECHNETIUM 99m SESTAMIBI
TUMOR IMAGING 377
LABELED MONOCLONAL
ANTIBODIES 378
NEUROPEPTIDE RECEPTOR
IMAGING 378
CONTENTS • XV
Somatostatin Receptor
Imaging 379
ADRENAL TUMOR IMAGING 382
POSITRON EMISSION
TOMOGRAPHY IMAGING
IN ONCOLOGY 382
FDG Tumor Imaging 382
LYMPHOSCINTIGRAPHY 384
Chapter 14
INFLAMMATION AND INFECTION
IMAGING 387
GALLIUM IMAGING 387
Mechanisms of Localization
of Inflammation 387
Technique 388
Clinical Applications 388
RADIOLABELED LEUKOCYTES 392
Mechanism of Localization 394
Indium 111 Oxine
Leukocytes 394
Labeling Principle 394
Technique 395
Normal Scan 395
Clinical Applications 395
Technetium 99m HMPAO
Leukocytes 400
Labeling 400
Technique 400
Clinical Applications 401
RADIOLABELED ANTIBODY
INFLAMMATION IMAGING 401
Nonspecific Polyclonal
Immunoglobulin G 401
Antigen Specific Labeled
Monoclonal Antibodies 402
MISCELLANEOUS
INFLAMMATION AGENTS 402
Chapter 15
LEGAL REQUIREMENTS AND
RADIATION SAFETY 405
REGULATORY AGENCIES 405
RADIATION SAFETY OFFICER 405
RADIATION SAFETY
COMMITTEE 406
QUALITY MANAGEMENT
PROGRAM 406
TYPES OF LICENSES 407
TRAINING 407
xvi • CONTENTS
Supervision and Visiting
Authorized User 408
TRANSPORTATION 409
RECEIPT OF RADIOACTIVE
SHIPMENTS 409
INSTRUMENTATION 410
Dose Calibrator 410
Survey Instruments 410
PREPARATION OF
RADIOPHARMACEUTICALS 411
MISADMINISTRATION OF
RADIOPHARMACEUTICALS 412
RELEASE OF PATIENTS CONTAINING
RADIOPHARMACEUTICALS 413
LABORATORY AREAS 414
SURVEYS 414
PERSONNEL MONITORING 415
WASTE DISPOSAL 416
Appendix A
CHARACTERISTICS OF RADIONUCLIDES
FOR IMAGING AND THERAPY 419
Appendix B l
RADIOACTIVITY CONVERSION TABLE
FOR INTERNATIONAL SYSTEM (SI) UNITS
(BECQUERELS TO CURIES) 421
Appendix B 2
RADIOACTIVITY CONVERSION TABLE
FOR INTERNATIONAL SYSTEM (SI) UNITS
(CURIES TO BECQUERELS) 422
Appendix C l
TECHNETIUM 99m DECAY AND
GENERATION TABLES 423
Appendix C 2
IODINE 131 AND STRONTIUM 89
DECAY CHARTS 424
Appendix D
INJECTION TECHNIQUES AND
PEDIATRIC DOSAGE INJECTION
TECHNIQUES 425
Appendix E
SAMPLE TECHNIQUES FOR NUCLEAR
IMAGING 427
Appendix F
RADIONUCLIDE IMAGING DURING
PREGNANCY 448
Appendix G l
GENERAL CONSIDERATIONS FOR
PATIENTS RECEIVING RADIONUCLIDE
THERAPY 451
Appendix G 2
SPECIAL CONSIDERATIONS AND
REQUIREMENTS FOR IODINE 131
THERAPY 455
Appendix H
EMERGENCY PROCEDURES FOR
RADIOACTIVE SPILLS 457
INDEX 459
|
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| spelling | Mettler, Fred A. Verfasser aut Essentials of nuclear medicine imaging Fred A. Mettler ; Milton J. Guiberteau 4. ed. Philadelphia [u.a.] Saunders 1998 XVI, 468 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Beeldverwerkende diagnostiek gtt Imagerie pour le diagnostic Nucleaire geneeskunde gtt Scintigraphie Diagnostic imaging Nuclear Medicine Radioisotope scanning Radionuclide Imaging Nuklearmedizin (DE-588)4042770-5 gnd rswk-swf Nuklearmedizin (DE-588)4042770-5 s DE-604 Guiberteau, Milton J. Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008361906&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mettler, Fred A. Guiberteau, Milton J. Essentials of nuclear medicine imaging Beeldverwerkende diagnostiek gtt Imagerie pour le diagnostic Nucleaire geneeskunde gtt Scintigraphie Diagnostic imaging Nuclear Medicine Radioisotope scanning Radionuclide Imaging Nuklearmedizin (DE-588)4042770-5 gnd |
| subject_GND | (DE-588)4042770-5 |
| title | Essentials of nuclear medicine imaging |
| title_auth | Essentials of nuclear medicine imaging |
| title_exact_search | Essentials of nuclear medicine imaging |
| title_full | Essentials of nuclear medicine imaging Fred A. Mettler ; Milton J. Guiberteau |
| title_fullStr | Essentials of nuclear medicine imaging Fred A. Mettler ; Milton J. Guiberteau |
| title_full_unstemmed | Essentials of nuclear medicine imaging Fred A. Mettler ; Milton J. Guiberteau |
| title_short | Essentials of nuclear medicine imaging |
| title_sort | essentials of nuclear medicine imaging |
| topic | Beeldverwerkende diagnostiek gtt Imagerie pour le diagnostic Nucleaire geneeskunde gtt Scintigraphie Diagnostic imaging Nuclear Medicine Radioisotope scanning Radionuclide Imaging Nuklearmedizin (DE-588)4042770-5 gnd |
| topic_facet | Beeldverwerkende diagnostiek Imagerie pour le diagnostic Nucleaire geneeskunde Scintigraphie Diagnostic imaging Nuclear Medicine Radioisotope scanning Radionuclide Imaging Nuklearmedizin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008361906&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mettlerfreda essentialsofnuclearmedicineimaging AT guiberteaumiltonj essentialsofnuclearmedicineimaging |