Growth factors and receptors: a practical approach
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Pr.
1998
|
| Schriftenreihe: | The practical approach series
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXII, 266 S. Ill., graph. Darst. |
| ISBN: | 0199636478 019963646X |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV012276528 | ||
| 003 | DE-604 | ||
| 005 | 19990630 | ||
| 007 | t | ||
| 008 | 981123s1998 ad|| |||| 00||| engod | ||
| 020 | |a 0199636478 |9 0-19-963647-8 | ||
| 020 | |a 019963646X |9 0-19-963646-X | ||
| 035 | |a (OCoLC)246376423 | ||
| 035 | |a (DE-599)BVBBV012276528 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-M49 |a DE-20 | ||
| 050 | 0 | |a QP552.G76 | |
| 082 | 0 | |a 571.84 | |
| 084 | |a WC 4150 |0 (DE-625)148092: |2 rvk | ||
| 084 | |a CHE 889f |2 stub | ||
| 084 | |a CHE 820f |2 stub | ||
| 245 | 1 | 0 | |a Growth factors and receptors |b a practical approach |c ed. by Ian A. McKay ... |
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Pr. |c 1998 | |
| 300 | |a XXII, 266 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a The practical approach series | |
| 650 | 0 | 7 | |a Methode |0 (DE-588)4038971-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Rezeptor |0 (DE-588)4049722-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Wachstumsfaktor |0 (DE-588)4188802-9 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Wachstumsfaktor |0 (DE-588)4188802-9 |D s |
| 689 | 0 | 1 | |a Rezeptor |0 (DE-588)4049722-7 |D s |
| 689 | 0 | 2 | |a Methode |0 (DE-588)4038971-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Wachstumsfaktor |0 (DE-588)4188802-9 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a MacKay, Ian A. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m GBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008321490&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-008321490 | ||
Datensatz im Suchindex
| _version_ | 1804126898062622720 |
|---|---|
| adam_text | WO GROWTH FACTORS AND RECEPTORS A PRACTICAL APPROACH EDITED BY IAN A.
MCKAY QUEEN MARY AND WESTFIELD COLLEGE, LONDON AND KENNETH D. BROWN THE
BABRAHAM INSTITUTE, CAMBRIDGE OXFORD NEW YORK TOKYO OXFORD UNIVERSITY
PRESS 1998 CONTENTS LIST OF CON TRIB U TORS ABBREVIATIONS 1. ENGINEERED
GROWTH FACTORS AND RECEPTORS, AND THEIR APPLICATIONS 1 IAN A. MCKAY,
STEPHEN A. BUSTIN, AND KENNETH D. BROWN 1. INTRODUCTION 1 KNOWN GROWTH
FACTORS AND RECEPTORS 1 MODES OF FACTOR-RECEPTOR INTERACTION 1 2.
APPLICATIONS OF ENGINEERED GROWTH FACTORS AND RECEPTORS 2 3. PRINCIPAL
METHODS FOR ENGINEERING GROWTH FACTORS AND THEIR RECEPTORS 2 MUTAGENESIS
2 FORMATION OF CHIMERIC PROTEINS 3 MANUFACTURE OF ALTERNATIVE LIGANDS
AND RECEPTORS 3 4. DESIGN OF ENGINEERED GROWTH FACTORS AND RECEPTORS 4
DNA SEQUENCE OF FACTOR OR RECEPTOR TO BE ENGINEERED 4 ANALYSIS OF
EXISTING DNA SEQUENCE FOR USEFUL RESTRICTION SITES 4 DESIGN OF WHOLLY
SYNTHETIC GROWTH FACTORS AND RECEPTORS 4 5. EXPRESSION OF DNAS ENCODING
GROWTH FACTORS OR RECEPTORS 7 DECIDING ON AN EXPRESSION SYSTEM 7
MICROBIAL EXPRESSION 9 IN VITRO EXPRESSION 10 EUKARYOTIC GENE EXPRESSION
11 ACKNOWLEDGEMENTS 17 REFERENCES 17 2. ENGINEERING OF NOVEL
NEUROTROPHINS 19 LEOPOLD L. HAG AND CARLOS F. IBDNEZ 1. INTRODUCTION 19
2. STRUCTURE-FUNCTION ANALYSES OF NEUROTROPHINS 20 CONTENTS 3.
SITE-DIRECTED MUTAGENESIS KUNKEL METHOD PCR-BASED MUTAGENESIS 4.
EXPRESSION OF RECOMBINANT PROTEIN COS CELL EXPRESSION BACULOVIRUS
EXPRESSION EXPRESSION OF RECOMBINANT PROTEINS IN PROKARYOTIC SYSTEMS (E.
COLI) 5. PROTEIN PURIFICATION 6. BIOCHEMICAL ASSAYS BINDING ASSAY
CROSS-LINKING ASSAY PHOSPHORYLATION ASSAY 7. BIOLOGICAL ASSAYS 8.
THERAPEUTIC POTENTIAL OF ENGINEERED NEUROTROPHINS 9. CONCLUSION
ACKNOWLEDGEMENTS REFERENCES 21 22 26 27 27 29 30 31 33 33 36 37 39 45 46
47 47 3. DESIGNING NEW AGONISTS/ANTAGONISTS OF GROWTH FACTOR
RECEPTORS*THE RATIONAL DESIGN OF A SUPERANTAGONIST OF THE IL-6 RECEPTOR
51 G. CILIBERTO, A. LAHM, G. PAONESSA, R. SAVINO, AND C. TONIATTI 1.
INTRODUCTION 51 2. MOLECULAR MODELLING OF A TRIMERIC IL-6/IL-6RA/GPL30
COMPLEX 53 MODEL CONSTRUCTION 53 IDENTIFICATION OF THE PUTATIVE IL-6
SITE 1 AND SITE 2 EPITOPES 53 3. IL-6 BIOLOGICAL ASSAY 54 4. IN VITRO
BINDING ASSAY OF IL-6 TO IL-6RA 58 5. IL-6 ANTAGONISTS MUTATED IN SITE
2: BIOCHEMICAL AND BIOLOGICAL EVALUATION 60 GENERATION OF IL-6
ANTAGONISTS 61 SPECIFICITY OF IL-6 ANTAGONISTS 63 6. TAG-MEDIATED
IMMUNOPRECIPITATION ASSAYS (TAMIA) 65 7. SELECTION OF AMINO ACID
SUBSTITUTIONS WHICH INCREASE AFFINITY OFIL-6FORIL-6RA GENERATION OF IL-6
PHAGE PARTICLES GENERATION OF IL-6 PHAGE LIBRARIES SELECTION OF IL-6
SUPERBINDERS FROM A PHAGE LIBRARY IL-6 VARIANTS WITH HIGHER AFFINITY FOR
IL-6RA CONTENTS 8. COMBINATION OF ANTAGONISTIC AND SUPERBINDER MUTATIONS
TO GENERATE IL-6 SUPERANTAGONISTS 77 9. POTENTIAL USE OF IL-6
SUPERANTAGONISTS IN THERAPY 78 ACKNOWLEDGEMENTS 79 REFERENCES 79 4. A
CHIMERIC APPROACH FOR STUDYING RECEPTOR BINDING DOMAINS IN EGF-LIKE
MOLECULES 83 E. J. J. VAN ZOELEN, A. E. G. LENFERINK, M. J. H, VAN VUGT,
AND M. L. M. VAN DE POLL 1. INTRODUCTION 83 2. CHIMERIC GROWTH FACTORS
84 3. EGF-RELATED FACTORS AND THEIR RECEPTORS 85 EGF-RELATED FACTORS 85
RECEPTORS FOR THE EGF-RELATED FACTORS 86 STRUCTURE-FUNCTION RELATIONSHIP
OF EGF AND TGFA 87 CHIMERIC PROTEINS OF THE EGF FAMILY 89 4. PREPARATION
AND ISOLATION OF RECOMBINANT EGF-LIKE GROWTH FACTORS 90 INTRODUCTION 90
CONSTRUCTION AND EXPRESSION OF EGF/TGFA CHIMERAS 93 5. CHARACTERIZATION
OF EGF/TGFA DOMAIN-EXCHANGE MUTANTS 98 INTRODUCTION 98 FUNCTIONAL
STUDIES ON EGF/TGFA CHIMERAS 105 ACKNOWLEDGEMENTS 105 REFERENCES 105 5.
STRUCTURE-ACTIVITY RELATIONSHIPS OF CHEMOKINES 109 IAN CLARK-LEWIS,
JENNIFER ANDERSON, PHILIP OWEN, LUAN VO, AND JIANG-HONG GONG 1.
INTRODUCTION 109 CHEMOKINES 110 PRIMARY STRUCTURE: PRACTICAL
CONSIDERATIONS 110 IMPORTANCE OF THE 3D STRUCTURE 111 2. DESIGN: TESTING
AN HYPOTHESIS 112 SINGLE SUBSTITUTIONS 112 MULTIPLE SUBSTITUTIONS 112
HYBRIDS/CHIMERAS 112 XI CONTENTS 3. PURIFICATION, FOLDING, AND ANALYSIS
113 SAMPLE PREPARATION AND RP-HPLC ANALYSIS 113 FOLDING 115 PURIFICATION
116 VERIFICATION OF COVALENT STRUCTURE 118 HANDLING AND STORAGE 118 4.
FUNCTIONAL ASSAYS 119 GENERAL CONSIDERATIONS 119 CELL MIGRATION 119 5.
RECEPTOR BINDING 120 IODINATION OF CHEMOKINES 120 RECEPTOR BINDING
ASSAYS 122 BINDABILITY AND KINETICS 123 REFERENCES 123 6. GENERATION AND
SELECTION OF RNA LIGANDS THAT INHIBIT THE INTERACTION OF VASCULAR
PERMEABILITY FACTOR/VASCULAR ENDOTHELIAL GROWTH FACTOR (VPF/VEGF) WITH
ITS RECEPTORS 125 LOUIS S. GREEN AND NEBOJSA JANJIC 1. INTRODUCTION TO
THE SELEX PROCESS 125 2. APPLICATION OF THE SELEX PROCESS TO IDENTIFYING
RNA LIGANDS TO VPF/VEGF RANDOM RNA LIBRARIES SELECTION CONDITIONS
CONSENSUS SEQUENCE AND SECONDARY STRUCTURE IDENTIFICATION MINIMAL
SEQUENCE DETERMINATION SELECTION OF VPF/VEGF ANATGONISTS: INHIBITION OF
RECEPTOR BINDING 3. METHODS FOR MAKING RNA LIGANDS NUCLEASE RESISTANT 4.
CLINICAL APPLICATIONS OF VPF/VEGF ANTAGONISTS REFERENCES 7.
IMMUNOLOCALIZATION AND RT-PCR FOR THE DETECTION AND QUANTIFICATION OF
GROWTH FACTOR AND RECEPTOR GENE EXPRESSION SIMON R. MYERS AND HARSHAD A.
NAVSARIA 1. INTRODUCTION ASSAYS OF PROTEIN EXPRESSION IN TISSUES ASSAYS
OF MRNA EXPRESSION IN TISSUES XII CONTENTS 2. IMMUNOLOCALIZATION OF
GROWTH FACTOR AND RECEPTOR PROTEIN 151 INTRODUCTION 151 TISSUE
PREPARATION 151 STORAGE AND DILUTION OF ANTIBODIES 152 DETECTION METHODS
152 CONTROLS 153 IMMUNOHISTOCHEMISTRY 155 3. SEMI-QUANTIFICATION OF
IMMUNOHISTOCHEMISTRY BY COMPUTER IMAGE ANALYSIS 157 INTRODUCTION 157
AVERAGE OD MEASUREMENT 158 4. INTERPRETATION OF IMMUNOHISTOCHEMISTRY
RESULTS 159 5. SEMI-QUANTIFICATION OF MRNA LEVELS USING NON-COMPETITIVE
RT-PCR 161 INTRODUCTION 161 EXTRACTION OF TOTAL RNA FROM SMALL TISSUE
SPECIMENS 162 REVERSE TRANSCRIPTION OF MRNA TO CDNA 163 PCR
AMPLIFICATION OF MRNA-DERIVED CDNA WITH SPECIFIC OLIGONUCLEOTIDE PRIMERS
164 DETECTION OF RT-PCR PRODUCT AND QUANTIFICATION 166 6. COMPETITIVE
RT-PCR QUANTIFICATION OF SPECIFIC MRNA LEVELS 168 INTRODUCTION 168
MUTANT TEMPLATES 168 USE OF MUTANT TEMPLATES IN TISSUE ANALYSIS 170 7.
INTERPRETATION OF RT-PCR AMPLIFICATION ANALYSES OF GENE EXPRESSION 171
REFERENCES 173 8. DEFINING GROWTH FACTOR FUNCTION THROUGH
TISSUE-SPECIFIC EXPRESSION OF DOMINANT- NEGATIVE RECEPTOR MUTANTS 175
SABINE WERNER 1. INTRODUCTION 175 THE CONCEPT OF DOMINANT-NEGATIVE
GROWTH FACTOR RECEPTORS 176 EXAMPLES OF EFFICIENT USE OF
DOMINANT-NEGATIVE GROWTH FACTOR RECEPTORS IN TRANSGENIC MICE 177 2.
DESIGN AND SYNTHESIS OF A GENE ENCODING A DOMINANT-NEGATIVE RECEPTOR
MUTANT 178 3. IDENTIFICATION OF TRANSGENIC MICE 179 4. ANALYSIS OF
TRANSGENE EXPRESSION 181 ADVANTAGES AND DISADVANTAGES OF VARIOUS RNA
DETECTION METHODS 181 XIII CONTENTS RNASE PROTECTION ASSAY 182 IN SITU
DETECTION OF TRANSGENE MRNA AND PROTEIN 188 5. CHARACTERIZATION OF THE
SKIN OF TRANSGENIC MICE 188 HISTOLOGICAL ANALYSIS 188 ANALYSIS OF
DIFFERENTIATION-SPECIFIC PROTEINS IN THE EPIDERMIS 190 LABELLING OF
PROLIFERATING CELLS WITH 5-BROMO-2 -DEOXYURIDINE (BRDU) 193
ACKNOWLEDGEMENTS 195 REFERENCES 196 9. GROWTH FACTOR*TOXIN CHIMERAS AND
THEIR APPLICATIONS 199 PAMELA A. DAVOL, A. RAYMOND FRACKELTON, JR., AND
PAUL CALABRESI 1. INTRODUCTION 199 2. DETECTING CHIMERIC FUNCTION 200
EVALUATING CYTOTOXICITY AS A FUNCTION OF TOXIN ACTIVITY 200 EVALUATING
CYTOTOXICITY AS A FUNCTION OF RECEPTOR SPECIFICITY 203 QUANTITATING
CYTOTOXIC ACTIVITY ON VARIOUS CELL LINES 208 ASSESSING ANTITUMOUR
EFFECTS IN ANIMALS 210 3. CLINICAL APPLICATIONS OF GROWTH FACTOR-TOXIN
CHIMERAS 214 CANCER THERAPY 214 OTHER APPLICATIONS 215 4. POTENTIAL
PROBLEMS IN USING BIOLOGICALLY ACTIVE CHIMERAS 216 PITFALLS ASSOCIATED
WITH THE TOXIN MOIETY 217 ADVERSE EFFECTS ASSOCIATED WITH GROWTH
FACTOR-TOXIN CHIMERAS 217 MECHANISMS OF RESISTANCE 219 5. CONCLUSIONS
223 REFERENCES 223 10. GENE THERAPY APPLICATIONS OF GROWTH FACTORS 227
TOR SVENSJO, FENG YAO, BOHDAN POMAHAC, AND ELOF ERIKSSON 1. INTRODUCTION
TO GENE THERAPY APPLICATIONS OF GROWTH FACTORS 227 GENE TRANSFER METHODS
228 GENE THERAPY WITH GROWTH FACTORS 232 2. GROWTH FACTOR APPLICATIONS
TO ENHANCE CUTANEOUS WOUND HEALING 234 3. GROWTH FACTOR EXPRESSION IN
SKIN 235 4. DETECTING GROWTH FACTOR EXPRESSION IN TARGET ORGANS 243 XIV
CONTENTS 5. DETERMINING THE EFFECTS OF GROWTH FACTORS ON WOUND HEALING
247 6. SUMMARY 248 REFERENCES 248 APPENDICES AL GROWTH FACTORS 253 A2
AMINO ACID ABBREVIATIONS 259 A3 NAMES AND ADDRESSES OF SUPPLIERS 261
INDEX 265 XV
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV012276528 |
| callnumber-first | Q - Science |
| callnumber-label | QP552 |
| callnumber-raw | QP552.G76 |
| callnumber-search | QP552.G76 |
| callnumber-sort | QP 3552 G76 |
| callnumber-subject | QP - Physiology |
| classification_rvk | WC 4150 |
| classification_tum | CHE 889f CHE 820f |
| ctrlnum | (OCoLC)246376423 (DE-599)BVBBV012276528 |
| dewey-full | 571.84 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.84 |
| dewey-search | 571.84 |
| dewey-sort | 3571.84 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Chemie |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01739nam a2200469 c 4500</leader><controlfield tag="001">BV012276528</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">19990630 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">981123s1998 ad|| |||| 00||| engod</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0199636478</subfield><subfield code="9">0-19-963647-8</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">019963646X</subfield><subfield code="9">0-19-963646-X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)246376423</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV012276528</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-M49</subfield><subfield code="a">DE-20</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QP552.G76</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">571.84</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4150</subfield><subfield code="0">(DE-625)148092:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">CHE 889f</subfield><subfield code="2">stub</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">CHE 820f</subfield><subfield code="2">stub</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Growth factors and receptors</subfield><subfield code="b">a practical approach</subfield><subfield code="c">ed. by Ian A. McKay ...</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford [u.a.]</subfield><subfield code="b">Oxford Univ. Pr.</subfield><subfield code="c">1998</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XXII, 266 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">The practical approach series</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Methode</subfield><subfield code="0">(DE-588)4038971-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Rezeptor</subfield><subfield code="0">(DE-588)4049722-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Wachstumsfaktor</subfield><subfield code="0">(DE-588)4188802-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Wachstumsfaktor</subfield><subfield code="0">(DE-588)4188802-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Rezeptor</subfield><subfield code="0">(DE-588)4049722-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Methode</subfield><subfield code="0">(DE-588)4038971-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Wachstumsfaktor</subfield><subfield code="0">(DE-588)4188802-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">MacKay, Ian A.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">GBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008321490&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-008321490</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV012276528 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:24:46Z |
| institution | BVB |
| isbn | 0199636478 019963646X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008321490 |
| oclc_num | 246376423 |
| open_access_boolean | |
| owner | DE-M49 DE-BY-TUM DE-20 |
| owner_facet | DE-M49 DE-BY-TUM DE-20 |
| physical | XXII, 266 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | Oxford Univ. Pr. |
| record_format | marc |
| series2 | The practical approach series |
| spelling | Growth factors and receptors a practical approach ed. by Ian A. McKay ... Oxford [u.a.] Oxford Univ. Pr. 1998 XXII, 266 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier The practical approach series Methode (DE-588)4038971-6 gnd rswk-swf Rezeptor (DE-588)4049722-7 gnd rswk-swf Wachstumsfaktor (DE-588)4188802-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Wachstumsfaktor (DE-588)4188802-9 s Rezeptor (DE-588)4049722-7 s Methode (DE-588)4038971-6 s DE-604 MacKay, Ian A. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008321490&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Growth factors and receptors a practical approach Methode (DE-588)4038971-6 gnd Rezeptor (DE-588)4049722-7 gnd Wachstumsfaktor (DE-588)4188802-9 gnd |
| subject_GND | (DE-588)4038971-6 (DE-588)4049722-7 (DE-588)4188802-9 (DE-588)4143413-4 |
| title | Growth factors and receptors a practical approach |
| title_auth | Growth factors and receptors a practical approach |
| title_exact_search | Growth factors and receptors a practical approach |
| title_full | Growth factors and receptors a practical approach ed. by Ian A. McKay ... |
| title_fullStr | Growth factors and receptors a practical approach ed. by Ian A. McKay ... |
| title_full_unstemmed | Growth factors and receptors a practical approach ed. by Ian A. McKay ... |
| title_short | Growth factors and receptors |
| title_sort | growth factors and receptors a practical approach |
| title_sub | a practical approach |
| topic | Methode (DE-588)4038971-6 gnd Rezeptor (DE-588)4049722-7 gnd Wachstumsfaktor (DE-588)4188802-9 gnd |
| topic_facet | Methode Rezeptor Wachstumsfaktor Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008321490&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mackayiana growthfactorsandreceptorsapracticalapproach |