Chemistry, health and environment:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Weinheim [u.a.]
Wiley-VCH
1999
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 345 S. Ill., graph. Darst. |
| ISBN: | 3527300872 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV012271666 | ||
| 003 | DE-604 | ||
| 005 | 20000425 | ||
| 007 | t | ||
| 008 | 981119s1999 ad|| |||| 00||| eng d | ||
| 016 | 7 | |a 956176721 |2 DE-101 | |
| 020 | |a 3527300872 |9 3-527-30087-2 | ||
| 035 | |a (OCoLC)246155578 | ||
| 035 | |a (DE-599)BVBBV012271666 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-20 |a DE-898 |a DE-355 |a DE-703 |a DE-384 |a DE-1028 |a DE-19 |a DE-858 |a DE-634 |a DE-11 |a DE-525 | ||
| 050 | 0 | |a RA1226 | |
| 082 | 0 | |a 615.902 |2 21 | |
| 084 | |a AR 25000 |0 (DE-625)8575: |2 rvk | ||
| 084 | |a VN 9200 |0 (DE-625)147637:253 |2 rvk | ||
| 084 | |a VN 9280 |0 (DE-625)147639:253 |2 rvk | ||
| 084 | |a WI 2500 |0 (DE-625)148774: |2 rvk | ||
| 084 | |a UMW 150f |2 stub | ||
| 100 | 1 | |a Sterner, Olov |d 1953- |e Verfasser |0 (DE-588)111824419 |4 aut | |
| 245 | 1 | 0 | |a Chemistry, health and environment |c Olov Sterner |
| 264 | 1 | |a Weinheim [u.a.] |b Wiley-VCH |c 1999 | |
| 300 | |a XV, 345 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 7 | |a Produits chimiques - Effets physiologiques |2 ram | |
| 650 | 7 | |a Toxicologie |2 ram | |
| 650 | 7 | |a Écotoxicologie |2 ram | |
| 650 | 4 | |a Carcinogens, Environmental | |
| 650 | 4 | |a Chemicals |x Physiological effect | |
| 650 | 4 | |a Environmental Pollutants | |
| 650 | 4 | |a Environmental toxicology | |
| 650 | 4 | |a Hazardous Substances |x metabolism | |
| 650 | 4 | |a Hazardous Substances |x toxicity | |
| 650 | 0 | 7 | |a Umwelttoxikologie |0 (DE-588)4121813-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Gesundheitsgefährdung |0 (DE-588)4071808-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Umweltchemikalie |0 (DE-588)4117281-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Ökologische Chemie |0 (DE-588)4135167-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Gesundheitsschädlicher Stoff |0 (DE-588)4020767-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Chemikalie |0 (DE-588)4009833-3 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Ökologische Chemie |0 (DE-588)4135167-8 |D s |
| 689 | 0 | 1 | |a Gesundheitsgefährdung |0 (DE-588)4071808-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Umweltchemikalie |0 (DE-588)4117281-4 |D s |
| 689 | 1 | 1 | |a Umwelttoxikologie |0 (DE-588)4121813-9 |D s |
| 689 | 1 | |5 DE-604 | |
| 689 | 2 | 0 | |a Chemikalie |0 (DE-588)4009833-3 |D s |
| 689 | 2 | 1 | |a Gesundheitsschädlicher Stoff |0 (DE-588)4020767-5 |D s |
| 689 | 2 | |5 DE-604 | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008317328&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-008317328 | |
Datensatz im Suchindex
| _version_ | 1807321520929767424 |
|---|---|
| adam_text |
Contents
1 Chemicals and society 1
1.1 Basic problems 1
1.2 Definition of the sciences involved 3
1.3 Trends and developments over the years 5
1.4 Legislation 7
1.5 Knowledge about chemical hazards 8
1.6 Acceptable chemical risks 10
2 Organic compounds 13
2.1 From atoms to molecules 13
2.1.1 Atoms 13
2.1.2 Covalent bonds 14
2.2 Classes of organic compounds 18
2.2.1 Hydrocarbons 18
2.2.1.1 Saturated hydrocarbons 18
2.2.1.2 Unsaturated hydrocarbons 19
2.2.1.3 Aromatic hydrocarbons 20
2.2.2 Chemical functionalities, first oxidation level 21
2.2.2.1 Functionalities containing oxygen 21
2.2.2.2 Functionalities containing nitrogen 23
2.2.2.3 Functionalities containing halogens 24
2.2.2.4 Functionalities containing sulphur 24
2.2.3 Chemical functionalities, second oxidation level 25
2.2.3.1 Aldehydes and ketones 25
2.2.3.2 Hemiacetals and acetals 26
2.2.3.3 Enols and similar compounds 26
2.2.4 Chemical functionalities, third oxidation level 27
2.2.4.1 Carboxylic acids, anhydrides and halides 27
2.2.4.2 Carboxylic acid esters, thioesters and amides 28
2.2.4.3 Nitriles 29
2.2.5 Chemical functionalities, fourth oxidation level 29
3 Chemical properties 30
3.1 Electronegativity, dipoles and ionic bonds 30
3.2 Intermolecular forces 32
X Contents
3.2.1 Covalent bonds 32
3.2.2 Forces between ions and dipoles 33
3.2.3 Hydrogen bonds 34
3.2.4 Charge transfer forces 35
3.2.5 van der Waals forces 35
3.3 Chemical properties 37
3.3.1 Volatility 37
3.3.2 Solubility 40
3.3.3 Adsorption and absorption 42
3.3.4 Persistence 43
3.3.5 Reactivity 44
3.3.5.1 Explosives 44
3.3.5.2 Acids and bases 45
3.3.5.3 Reducing and oxidizing agents 46
3.3.5.4 Excited molecules 46
3.3.5.5 Electrophilic compounds 47
3.3.5.6 Radicals 47
3.3.5.7 Non covalent binding 48
3.4 Reactions between nucleophiles and electrophiles 48
3.4.1 Nucleophilic substitutions 48
3.4.2 Nucleophilic additions 51
• 3.4.3 The electrophile 51
3.4.3.1 Strained cyclic hydrocarbons and heterocycles 52
3.4.3.2 Weak single bonds between a sp3 carbon and a leaving group 53
3.4.3.3 Polarized double or triple bonds 56
3.4.4 The nucleophile 57
3.5 Radical reactions 58
3.6 Factors modulating reactivity 59
3.6.1 Electronic effects 59
3.6.2 Steric factors 62
3.6.3 Transformations and conversions that increase reactivity 63
4 The chemicals of nature 64
4.1 The cell 64
4.1.1 Human cell types 65
4.1.2 The basic components and functions of a cell 66
4.2 Chemicals 68
4.2.1 Endogenous vs exogenous chemicals 68
4.2.2 Natural vs synthetic compounds 69
4.3 Biochemicals 71
4.3.1 Water 71
4.3.2 Carbohydrates 71
4.3.3 Fatty acids 73
I
'; Contents
4.3.4 Terpenoids 74
4.3.5 Amino acids 76
4.3.6 Nucleosides 77
4.4 Biomacromolecules and cellular constituents 79
4.4.1 Cell membranes 79
4.4.2 Proteins 80
4.4.3 Nucleic acids 81
4.5 Basic environmental chemistry 83
4.5.1 The atmosphere 84
4.5.2 The hydrosphere 84
4.5.3 The lithosphere and the pedosphere 86
4.5.4 The turnover of chemicals in and between the spheres 87
5 Toxicological concepts 89
5.1 The toxicity of different chemicals 89
5.2 Toxicological concepts 91
5.2.1 Acute and chronic effects 91
5.2.2 Reversible and irreversible effects 92
5.2.3 Local and systemic effects, target organs 92
5.2.4 Independent, additive, synergistic and antagonistic effects 93
5.2.5 Tolerance 94
5.3 Factors modulating toxicity 94
5.3.1 The purity and physical state of the toxicant 94
5.3.2 The exposure 94
5.3.3 The victim 96
5.3.3.1 Species related differences 96
5.3.3.2 Sex related differences 97
5.3.3.3 Age related differences 97
5.3.3.4 Individual differences 97
5.4 Acute toxicity 98
5.4.1 Measures for acute toxicity 98
5.4.2 Specific and non specific toxicity 99
5.4.3 Selective and non selective toxicity 101
5.5 Interpretation of results from toxicological testing 102
6 Uptake, distribution and elimination of chemicals 105
6.1 Transport through biological membranes 105
6.1.1 Diffusion 105
6.1.2 Passive transport by proteins 106
6.1.3 Active transport by proteins 109
6.1.4 Exocytosis and endocytosis 110
6.2 Absorption of chemicals in man 111
6.2.1 Absorption via the skin 111
XII Contents
6.2.2 Uptake by the gastrointestinal tract 113
6.2.3 Uptake via the lungs 117
6.2.3.1 Air contaminants in the form of aerosols 118
6.2.3.2 Air contaminants in the form of gases and vapours 119
6.3 Bioaccumulation 120
6.4 Distribution of chemicals in organisms 121
6.4.1 Chemical properties 121
6.4.2 Biological barriers 122
6.4.3 Uptake as a function of distribution 123
6.5 Excretion of chemicals from man 125
6.5.1 Excretion via the lungs 125
6.5.2 Excretion via the liver 126
6.5.3 Excretion via the kidneys 127
7 Metabolism of exogenous compounds in mammals the principal conversions 130
7.1 Overview 131
7.2 Enzymatic systems involved in oxidations 132
7.2.1 Primary and secondary metabolism 133
7.2.2 Cytochrome P 450 133
7.2.3 Generation of reactive oxygen species 136
7.2.4 Other oxidative enzymes 139
7.3 Phase I conversions 141
7.3.1 Oxidations 142
7.3.1.1 Epoxidations of carbon carbon multiple bonds 142
7.3.1.2 Hydroxylations of saturated carbon 144
7.3.1.3 Hydroxylation of amino groups 147
7.3.1.4 Oxidation of single bond to double bond 148
7.3.1.5 Oxidation of heteroatoms 149
7.3.1.6 Oxidation of alcohols and aldehydes 150
7.3.2 Reductions 150
7.3.3 Hydrolyses 152
7.3.3.1 Hydrolysis of epoxides 152
7.3.3.2 Hydrolysis of esters and amides 155
7.4 Phase II conversions (conjugations) 156
7.4.1 Conjugations with sulphate 156
7.4.2 Conjugations with glucuronic acid 158
7.4.3 Conjugations with amino acids 159
7.4.4 Conjugations with glutathione 160
7.4.5 Other conjugations 163
7.5 Summary of the major phase I and phase II reactions 165
Contents
j 8 Metabolism of exogenous compounds in mammals 166
| 8.1 Metabolism of hydrocarbons 166
i 8.2 Metabolism of compounds containing nitrogen 173
i 8.3 Metabolism of compounds containing halogen 181
8.4 Metabolism of compounds containing sulphur 186
9 Conversions and transformations in the environment 188
9.1 Enzymatic conversions 188
9.1.1 Biodegradation of saturated hydrocarbons 190
9.1.2 Biodegradation of benzene 190
9.1.3 B iodegradation of alkyIbenzenes 193
9.1.4 Biodegradation of fused ring aromatic compounds 193
9.1.5 Biodegradation of halogenated aromatic compounds 194
9.2 Chemical transformations 196
9.2.1 Oxidations 197
9.2.2 Hydrolyses 197
9.2.3 Substitutions, eliminations and additions 200
9.3 Transformations induced by radiation 202
9.3.1 Photolysis 203
9.3.2 Isomerization/rearrangement 203
9.3.3 Additions/eliminations 204
9.3.4 Photoionization 204
9.3.5 Electron transfer 205
9.3.6 Sensitization 206
10 Toxic effects of chemicals 208
10.1 General toxic effects 208
10.1.1 Non specific effects of lipophilic and amphipathic compounds 208
10.1.2 Lipid peroxidation 209
10.1.3 Acidosis 213
10.1.4 Oxygen deficiency due to effects on the blood 217
10.1.4.1 Carbon monoxide 218
10.1.4.2 Methaemoglobinemia 220
10.1.5 ATP deficiency due to inhibition of the primary metabolism 221
10.1.5.1 Inhibition of the citric acid cycle 222
10.1.5.2 Inhibition of the respiratory chain 223
10.1.5.3 Uncoupling of the oxidative phosphorylation 225
10.2 Specific toxic effects to organs (or equivalents) 226
10.2.1 Effects on the blood 226
10.2.2 Effects on the nervous system 226
10.2.3 Effects on the liver 231
XIV Contents
|
10.2.4 Effects on the kidneys 233 j
10.2.5 Effects on the respiratory system 233 I
10.2.6 Effects on the skin 235 |
10.3 Chemical allergens 236 i
10.3.1 Immediate hypersensitivity 238
10.3.2 Delayed type hypersensitivity 239
10.4 Chemical teratogenicity 240
11 The molecular basis for genotoxicity and carcinogenicity 245
11.1 Chromosomes, genes and mutations 245
11.2 DNA as a molecular target 248
11.3 Chemical effects on DNA and DNA handling systems 249
11.3.1 Modification of the DNA bases 249
11.3.2 Intercalation 252
11.3.3 Loss of modified bases 252
11.3.4 Modification of other macromolecules 253
11.4 Different types of mutations 254
11.4.1 Point mutations 254
11.4.1.1 Base pair substitution mutations 254
11.4.1.2 Frame shift mutations 255
11.4.2 Chromosome aberrations 256
11.5 Chemical mutagenesis 257
11.6 Effects of mutations 259
11.6.1 Effects of mutations in germ cells 259
11.6.2 Effects of mutations in embryo cells 260
11.6.3 Effects of mutations in somatic cells 261
11.6.4 Which mutation is most serious? 261
11.7 Chemicals and cancer 262
11.8 Chemical carcinogenesis 264
11.8.1 Reactive or proreactive chemical carcinogens that act on DNA 265
11.8.1.1 Electrophiles 265
11.8.1.2 Radicals or reactive products formed after radical reactions 265
11.8.1.3 Metal ions 266
11.8.2 Chemical carcinogens affecting DNA by indirect mechanisms 266
11.8.2.1 Chemicals acting on the components of DNA metabolism 266
11.8.2.2 Alteration of gene expression 267
11.8.2.3 Mitogenic chemicals 267
11.8.2.4 Cocarcinogens and promotors 268
11.8.2.5 Immunosuppressive agents 269
11.8.2.6 Hormones 269
11.9 Oncogenes, proto oncogenes and anti oncogenes 270
Contents
I
! 12 Environmental effects of chemicals 274
| 12.1 Natural emission of chemicals 274
; 12.1.1 Inorganic chemicals 274
\ 12.1.2 Organic chemicals 275
; 12.1.2.1 Hydrocarbons 276
12.1.2.2 Sulphur compounds 276
12.1.2.3 Halogenated compounds 276
12.2 Smog and other air pollution 277
12.2.1 Degradation of trace gases in the troposphere 278
12.2.2 Photochemical oxidants 279
12.3 Acid pollution 280
12.4 Depletion of stratospheric ozone 281
12.5 Greenhouse effect 284
12.6 Pollution by halogenated hydrocarbons 288
12.6.1 Dioxins 288
12.6.2 PCB 290
12.6.3 DDT 291
12.7 Pollution by metals 292
12.7.1 Arsenic (As) 293
12.7.2 Cadmium (Cd) 294
12.7.3 Chromium (Cr) 295
12.7.4 Copper (Cu) 295
12.7.5 Lead(Pb) 296
12.7.6 Mercury (Hg) 297
12.7.7 Tin(Sn) 298
13 The assessment of organic structures 300
Glossary 306
Index 326 |
| any_adam_object | 1 |
| author | Sterner, Olov 1953- |
| author_GND | (DE-588)111824419 |
| author_facet | Sterner, Olov 1953- |
| author_role | aut |
| author_sort | Sterner, Olov 1953- |
| author_variant | o s os |
| building | Verbundindex |
| bvnumber | BV012271666 |
| callnumber-first | R - Medicine |
| callnumber-label | RA1226 |
| callnumber-raw | RA1226 |
| callnumber-search | RA1226 |
| callnumber-sort | RA 41226 |
| callnumber-subject | RA - Public Medicine |
| classification_rvk | AR 25000 VN 9200 VN 9280 WI 2500 |
| classification_tum | UMW 150f |
| ctrlnum | (OCoLC)246155578 (DE-599)BVBBV012271666 |
| dewey-full | 615.902 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.902 |
| dewey-search | 615.902 |
| dewey-sort | 3615.902 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Allgemeines Biologie Umwelt Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV012271666</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20000425</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">981119s1999 ad|| |||| 00||| eng d</controlfield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">956176721</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527300872</subfield><subfield code="9">3-527-30087-2</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)246155578</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV012271666</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-20</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-384</subfield><subfield code="a">DE-1028</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-858</subfield><subfield code="a">DE-634</subfield><subfield code="a">DE-11</subfield><subfield code="a">DE-525</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RA1226</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615.902</subfield><subfield code="2">21</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">AR 25000</subfield><subfield code="0">(DE-625)8575:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VN 9200</subfield><subfield code="0">(DE-625)147637:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VN 9280</subfield><subfield code="0">(DE-625)147639:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WI 2500</subfield><subfield code="0">(DE-625)148774:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">UMW 150f</subfield><subfield code="2">stub</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Sterner, Olov</subfield><subfield code="d">1953-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)111824419</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Chemistry, health and environment</subfield><subfield code="c">Olov Sterner</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Weinheim [u.a.]</subfield><subfield code="b">Wiley-VCH</subfield><subfield code="c">1999</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XV, 345 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Produits chimiques - Effets physiologiques</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Toxicologie</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Écotoxicologie</subfield><subfield code="2">ram</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Carcinogens, Environmental</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chemicals</subfield><subfield code="x">Physiological effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Environmental Pollutants</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Environmental toxicology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hazardous Substances</subfield><subfield code="x">metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hazardous Substances</subfield><subfield code="x">toxicity</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Umwelttoxikologie</subfield><subfield code="0">(DE-588)4121813-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Gesundheitsgefährdung</subfield><subfield code="0">(DE-588)4071808-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Umweltchemikalie</subfield><subfield code="0">(DE-588)4117281-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Ökologische Chemie</subfield><subfield code="0">(DE-588)4135167-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Gesundheitsschädlicher Stoff</subfield><subfield code="0">(DE-588)4020767-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Chemikalie</subfield><subfield code="0">(DE-588)4009833-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Ökologische Chemie</subfield><subfield code="0">(DE-588)4135167-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Gesundheitsgefährdung</subfield><subfield code="0">(DE-588)4071808-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Umweltchemikalie</subfield><subfield code="0">(DE-588)4117281-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Umwelttoxikologie</subfield><subfield code="0">(DE-588)4121813-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="2" ind2="0"><subfield code="a">Chemikalie</subfield><subfield code="0">(DE-588)4009833-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="2" ind2="1"><subfield code="a">Gesundheitsschädlicher Stoff</subfield><subfield code="0">(DE-588)4020767-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="2" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008317328&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-008317328</subfield></datafield></record></collection> |
| id | DE-604.BV012271666 |
| illustrated | Illustrated |
| indexdate | 2024-08-14T00:41:55Z |
| institution | BVB |
| isbn | 3527300872 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008317328 |
| oclc_num | 246155578 |
| open_access_boolean | |
| owner | DE-20 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-703 DE-384 DE-1028 DE-19 DE-BY-UBM DE-858 DE-634 DE-11 DE-525 |
| owner_facet | DE-20 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-703 DE-384 DE-1028 DE-19 DE-BY-UBM DE-858 DE-634 DE-11 DE-525 |
| physical | XV, 345 S. Ill., graph. Darst. |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Wiley-VCH |
| record_format | marc |
| spelling | Sterner, Olov 1953- Verfasser (DE-588)111824419 aut Chemistry, health and environment Olov Sterner Weinheim [u.a.] Wiley-VCH 1999 XV, 345 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Produits chimiques - Effets physiologiques ram Toxicologie ram Écotoxicologie ram Carcinogens, Environmental Chemicals Physiological effect Environmental Pollutants Environmental toxicology Hazardous Substances metabolism Hazardous Substances toxicity Umwelttoxikologie (DE-588)4121813-9 gnd rswk-swf Gesundheitsgefährdung (DE-588)4071808-6 gnd rswk-swf Umweltchemikalie (DE-588)4117281-4 gnd rswk-swf Ökologische Chemie (DE-588)4135167-8 gnd rswk-swf Gesundheitsschädlicher Stoff (DE-588)4020767-5 gnd rswk-swf Chemikalie (DE-588)4009833-3 gnd rswk-swf Ökologische Chemie (DE-588)4135167-8 s Gesundheitsgefährdung (DE-588)4071808-6 s DE-604 Umweltchemikalie (DE-588)4117281-4 s Umwelttoxikologie (DE-588)4121813-9 s Chemikalie (DE-588)4009833-3 s Gesundheitsschädlicher Stoff (DE-588)4020767-5 s HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008317328&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Sterner, Olov 1953- Chemistry, health and environment Produits chimiques - Effets physiologiques ram Toxicologie ram Écotoxicologie ram Carcinogens, Environmental Chemicals Physiological effect Environmental Pollutants Environmental toxicology Hazardous Substances metabolism Hazardous Substances toxicity Umwelttoxikologie (DE-588)4121813-9 gnd Gesundheitsgefährdung (DE-588)4071808-6 gnd Umweltchemikalie (DE-588)4117281-4 gnd Ökologische Chemie (DE-588)4135167-8 gnd Gesundheitsschädlicher Stoff (DE-588)4020767-5 gnd Chemikalie (DE-588)4009833-3 gnd |
| subject_GND | (DE-588)4121813-9 (DE-588)4071808-6 (DE-588)4117281-4 (DE-588)4135167-8 (DE-588)4020767-5 (DE-588)4009833-3 |
| title | Chemistry, health and environment |
| title_auth | Chemistry, health and environment |
| title_exact_search | Chemistry, health and environment |
| title_full | Chemistry, health and environment Olov Sterner |
| title_fullStr | Chemistry, health and environment Olov Sterner |
| title_full_unstemmed | Chemistry, health and environment Olov Sterner |
| title_short | Chemistry, health and environment |
| title_sort | chemistry health and environment |
| topic | Produits chimiques - Effets physiologiques ram Toxicologie ram Écotoxicologie ram Carcinogens, Environmental Chemicals Physiological effect Environmental Pollutants Environmental toxicology Hazardous Substances metabolism Hazardous Substances toxicity Umwelttoxikologie (DE-588)4121813-9 gnd Gesundheitsgefährdung (DE-588)4071808-6 gnd Umweltchemikalie (DE-588)4117281-4 gnd Ökologische Chemie (DE-588)4135167-8 gnd Gesundheitsschädlicher Stoff (DE-588)4020767-5 gnd Chemikalie (DE-588)4009833-3 gnd |
| topic_facet | Produits chimiques - Effets physiologiques Toxicologie Écotoxicologie Carcinogens, Environmental Chemicals Physiological effect Environmental Pollutants Environmental toxicology Hazardous Substances metabolism Hazardous Substances toxicity Umwelttoxikologie Gesundheitsgefährdung Umweltchemikalie Ökologische Chemie Gesundheitsschädlicher Stoff Chemikalie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008317328&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT sternerolov chemistryhealthandenvironment |