Pathology of bone marrow:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Baltimore [u.a.]
Williams & Wilkins
1998
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 486 S. Ill. |
| ISBN: | 0683303368 |
Internformat
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| 245 | 1 | 0 | |a Pathology of bone marrow |c Faramarz Naeim |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Baltimore [u.a.] |b Williams & Wilkins |c 1998 | |
| 300 | |a XV, 486 S. |b Ill. | ||
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| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Bone Marrow Diseases | |
| 650 | 4 | |a Bone Marrow |x pathology | |
| 650 | 4 | |a Bone marrow |x Diseases | |
| 650 | 4 | |a Hematopoietic stem cell disorders | |
| 650 | 4 | |a Myeloproliferative disorders | |
| 650 | 0 | 7 | |a Pathologie |0 (DE-588)4044893-9 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1804126878526603264 |
|---|---|
| adam_text | 1. BONE MARROW STRUCTURE AND FUNCTION 1
Bone Marrow Structure 1
Hematopoiesis and Regulatory Mechanisms 4
Hematopoiesis 4
Hematopoietic Stem Cells 6
Cytokines 9
Morphologic Characteristics of Bone Marrow Cells 13
Neutrophilic Precursors 13
Basophils and Mast Cells 16
The Monocyte Macrophage Lineage 18
Erythroid Precursors 19
Platelet Precursors 20
Lymphocytes and Plasma Cells 23
Osteoblasts and Osteoclasts 27
Adipocytes 27
Fibroblast Like Cells and Endothelial Cells 28
2. BONE MARROW EXAMINATION: SPECIAL
PROCEDURES 37
Sample Preparation 37
Special Stains 40
Monoclonal Antibodies 46
DNA Content and Cell Cycle Analysis 64
DNA Hybridization Techniques 66
Cytogenetic Analysis 70
Electron Microscopy 71
Bone Marrow Culture 72
3. ABNORMAL MORPHOLOGY: GENERAL
CONSIDERATIONS 82
Abnormal Erythroid Morphology 82
Abnormal Leukocyte Morphology 83
Abnormal Bone Marrow Cellularity 89
Bone Marrow Fibrosis 90
Granulomas 92
Bone Marrow Changes in Acquired Immunodeficiency Syndrome 94
Gelatinous Transformation 94
Bone Marrow Necrosis 99
Leukemias and Lymphomas 100
Bone Marrow Metastasis 100
Previous Biopsy Site/Repair 107
Post Therapeutic Changes 108
Contents
4. CLONAL HEMATOPOIESIS AND EVOLUTION TO
HEMATOLOGIC MALIGNANCIES 116
Oncogenes 116
Tumor Suppressor Genes 120
5. BONE MARROW HYPOPLASIA 125
Constitutional Aplastic Anemia 125
Acquired Aplastic Anemia 126
Paroxysmal Nocturnal Hemoglobinuria 130
Differential Diagnosis 133
Therapeutic Approaches 135
6. MYELODYSPLASTIC SYNDROMES (MDS) 140
Etiology and Pathogenesis 140
Pathology 141
French American British (FAB) Classification 143
Refractory Anemia 146
Refractory Anemia with Ringed Sideroblasts 146
Refractory Anemia with Excess Blasts 147
Chronic Myelomonocytic Leukemia 148
Refractory Anemia with Excess Blasts in Transformation 152
Other Subtypes 152
Other Related Disorders 153
Therapy related MDS 153
Hypocellular MDS 153
MDS with Fibrosis 154
Pediatric MDS 154
Non Clonal MDS 155
7. CHRONIC MYELOPROLIFERATIVE DISORDERS 166
Polycythemia Vera 166
Essential Thrombocythemia 168
Myelofibrosis with Myeloid Metaplasia 172
Chronic Myelogenous Leukemia 176
Atypical CML 180
Other Subtypes 180
8. OTHER DIFFERENTIATED MYELOPROLIFERATIVE
DISORDERS 189
Chronic Neutrophilic Leukemia 189
Chronic Eosinophilic Leukemia 189
Chronic Monocytic Leukemia 191
Basophilic Leukemia 191
Mast Cell Leukemia 191
9. ACUTE LEUKEMIAS 194
Acute Myelogenous Leukemia 194
FAB Classification 197
Acute Myeloblasts Leukemia, Minimally Differentiated
(AML M0) 197
Acute Myeloblastic Leukemia without Maturation (AML M1) 198
Contents xiii
Acute Myeloblastic Leukemia with Maturation (AML M2) 198
Acute Promyelocytic Leukemia (AML M3) 199
Acute Myelomonocytic Leukemia (AML M4) 202
Acute Monocytic Leukemia (AML M5) 204
Erythroleukemia (AML M6) 207
Acute Megakaryoblastic Leukemia (AML M7) 210
Other Types of Acute Myelogenous Leukemia 211
Acute Lymphoblastic Leukemia 220
Morphologic (FAB) Classification 221
Other Morphologic Variants 223
Immunologic Classification 225
Acute Mixed Lineage Leukemia 232
AML Expressing Lymphoid Associated Markers (LY + AML) 233
ALL Expressing Myeloid Associated Markers (MY + ALL) 234
Other Bi or Multi Phenotypic Leukemias 234
Synchronous Acute Bilinear or Biclonal Leukemias 235
Lineage Switch in Acute Leukemias 235
Post Therapeutic Bone Marrow Changes in Patients with Acute
Leukemia 235
Detection of Residual Disease in Acute Leukemia 237
Relapse 240
10. CHRONIC LYMPHOID LEUKEMIAS AND RELATED
DISORDERS 255
Chronic Lymphocytic Leukemia 255
Development of More Aggressive Lymphoid Malignancies in Patients
with CLL 262
Prolymphocytic Leukemia 264
Hairy Cell Leukemia 267
Large Granular Lymphocytic Leukemia 273
HTLV Associated Leukemia /Lymphoma 275
Other Types of T Cell Chronic Lymphoid Leukemia 278
Sezary Syndrome 278
SlOO Positive T CLL 281
Splenic Lymphoma with Villous Lymphocytes 281
Leukemic Phase of Other Lymphomas 281
11. MALIGNANT LYMPHOMAS 291
Hodgkin s Disease 291
Classification 291
Non Hodgkin s Lymphoma 297
Classification 297
Low Grade Lymphomas 298
Other Mature B Cell Lymphomas 303
Mantle Cell Lymphoma 303
Marginal Zone B Cell Lymphoma 305
Intermediate Grade Lymphomas 307
High Grade Lymphomas 308
Other Types of Aggressive Lymphomas 313
Angioimmunoblastic T Cell Type 313
Angiocentric (T/NK) Cell Lymphoma 313
CD 30+ Anaplastic Large Cell Lymphoma 314
Contents
12. PLASMA CELL DYSCRASIAS 328
Monoclonal Gammopathy of Undetermined Significance 329
Multiple Myeloma and Plasmacytoma 330
IgM Monoclonal Gammopathy 337
Heavy Chain Disease 337
Light Chain Associated Amyloidosis 340
13. MONOCYTIC AND HISTIOCYTIC DISORDERS 349
Histiocytosis 349
Langerhans Cell Histiocytosis 349
Hemophagocytic Syndromes 354
Malignant Histiocytosis 358
Malignant Tumors of Dendritic Cells 359
Gaucher s Disease 360
Niemann Pick Disease 362
14. GRANULOCYTIC DISORDERS 368
Chediak Higashi Syndrome 368
Chronic Granulomatous Disease 368
Myeloperoxidase Deficiency 370
Leukocyte Adhesion Deficiency 370
Congenital Neutropenia 371
Cyclic Neutropenia 371
Autoimmune Neutropenia 371
Neutrophilia 374
Hypereosinophilic Syndrome 375
Mastocytosis 377
Transient Myeloproliferative Disorder in Down s Syndrome 379
15. LYMPHOCYTIC DISORDERS 384
Congenital Immunodeficiency Syndromes 384
Severe Combined Immunodeficiency 384
Di George Syndrome 384
Wiscott Aldrich Syndrome 384
Aggamaglobulinema 385
Acquired Immunodeficiency Syndrome 385
Idiopathic CD4 + T lymphocytopenia 388
Infectious Mononucleosis 389
X linked Lymphoproliferative Syndrome 390
Idiopathic Lymphocytosis 390
Chronic B Cell Lymphocytosis 391
Polyclonal Immunoblastic Proliferations 391
Bone Marrow Benign Lymphoid Aggregates 391
16. DISORDERS OF RED BLOOD CELLS 396
Classification 396
Disturbance of Proliferation and Differentiation of Erythroid Progenitor
Cell 396
Pure Red Cell aplasia 396
Congenital Dyserythropoietic Anemia 398
Megaloblastic Anemia 401
Contents xv
Iron Deficiency Anemia 405
Thalassemias 407
Sickle Cell Diseases 411
Unstable Hemoglobins 413
Erythrocyte Membrane Skeleton Defects 415
Hereditary Spherocytosis 415
Hereditary Elliptocytosis 415
Other Membrane Associated Abnormalities 417
Hemolytic Anemias Secondary to Erythrocyte Enzyme
Abnormalities 418
Glucose 6 Phosphate Dehydrogenase Deficiency 418
Pyrovate Kinase Deficiency 418
Immune Related Hemolytic Anemias 420
Nonimmune Acquired Hemolytic Anemias 423
Other Types of Anemia 425
17. DISORDERS OF MEGAKARYOCYTES AND
PLATELETS 434
Megakaryocytosis 434
Thrombocytopenia 435
Autoimmune Thrombocytopenic Purpura 436
Drug Induced Immune Thrombocytopenia 437
Neonatal Immune Thrombocytopenia 438
Post Transfusion Purpura 438
Thrombocytopenia in Allergic and Anaphylactic Reactions 439
Thrombotic Thrombocytopenic Purpura 439
Other Thrombocytopenias 440
Qualitative Platelet Disorders 440
Congenital 441
Acquired 444
Platelet Dysfunction Associated with Pathologic Conditions 444
18. BONE MARROW TRANSPLANTATION 453
Principles of Bone Marrow Transplantation 453
Aplastic Anemia 455
Acute Lymphoblastic Leukemia 455
Acute Myelogenous Leukemia 456
Chronic Myelogenous Leukemia 457
Hodgkin s and Non Hodgkin s Lymphoma 457
Multiple Myeloma 458
Thalassemia and Sickle Cell Anemia 458
Complications of Bone Marrow Transplantation 459
Morphologic Evaluation of Bone Marrow 459
Before and After Transplantations 459
|
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| discipline | Medizin |
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| id | DE-604.BV012260276 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:24:27Z |
| institution | BVB |
| isbn | 0683303368 |
| language | English |
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| physical | XV, 486 S. Ill. |
| publishDate | 1998 |
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| publisher | Williams & Wilkins |
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| spelling | Naeim, Faramarz Verfasser aut Pathology of bone marrow Faramarz Naeim 2. ed. Baltimore [u.a.] Williams & Wilkins 1998 XV, 486 S. Ill. txt rdacontent n rdamedia nc rdacarrier Bone Marrow Diseases Bone Marrow pathology Bone marrow Diseases Hematopoietic stem cell disorders Myeloproliferative disorders Pathologie (DE-588)4044893-9 gnd rswk-swf Knochenmarkkrankheit (DE-588)4228476-4 gnd rswk-swf Knochenmarkkrankheit (DE-588)4228476-4 s Pathologie (DE-588)4044893-9 s 1\p DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008308380&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Naeim, Faramarz Pathology of bone marrow Bone Marrow Diseases Bone Marrow pathology Bone marrow Diseases Hematopoietic stem cell disorders Myeloproliferative disorders Pathologie (DE-588)4044893-9 gnd Knochenmarkkrankheit (DE-588)4228476-4 gnd |
| subject_GND | (DE-588)4044893-9 (DE-588)4228476-4 |
| title | Pathology of bone marrow |
| title_auth | Pathology of bone marrow |
| title_exact_search | Pathology of bone marrow |
| title_full | Pathology of bone marrow Faramarz Naeim |
| title_fullStr | Pathology of bone marrow Faramarz Naeim |
| title_full_unstemmed | Pathology of bone marrow Faramarz Naeim |
| title_short | Pathology of bone marrow |
| title_sort | pathology of bone marrow |
| topic | Bone Marrow Diseases Bone Marrow pathology Bone marrow Diseases Hematopoietic stem cell disorders Myeloproliferative disorders Pathologie (DE-588)4044893-9 gnd Knochenmarkkrankheit (DE-588)4228476-4 gnd |
| topic_facet | Bone Marrow Diseases Bone Marrow pathology Bone marrow Diseases Hematopoietic stem cell disorders Myeloproliferative disorders Pathologie Knochenmarkkrankheit |
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