Introduction to oncogenes and molecular cancer medicine:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer
1998
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 168 S. Ill., graph. Darst. |
| ISBN: | 0387983929 |
Internformat
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| 100 | 1 | |a Ross, Dennis W. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Introduction to oncogenes and molecular cancer medicine |c Dennis W. Ross |
| 264 | 1 | |a New York [u.a.] |b Springer |c 1998 | |
| 300 | |a XII, 168 S. |b Ill., graph. Darst. | ||
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| 650 | 7 | |a Moleculaire biologie |2 gtt | |
| 650 | 7 | |a Oncogenen |2 gtt | |
| 650 | 4 | |a Cancer |x Molecular aspects | |
| 650 | 4 | |a Cell Transformation, Neoplastic | |
| 650 | 4 | |a Neoplasms |x etiology | |
| 650 | 4 | |a Neoplasms |x genetics | |
| 650 | 4 | |a Oncogenes | |
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Datensatz im Suchindex
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Contents
Preface vii
Acknowledgments ix
Part I Basic Principles of Molecular Biology
1 Molecular Biology of Cells 3
Overview: What Is a Gene? • The Human Genome—Physical
Structure • The Human Genome—Information Content •
Anatomy of a Gene • Basic Genetics • Summary • References
2 Cell Growth and Senescence 17
Overview • Cell Culture Model • Cell Cycle • DNA Synthesis •
DNA Repair • Checkpoints • Apoptosis • Aging—An Aside •
Summary • References
3 Oncogenes: Control of Cell Growth and Senescence .... 29
Overview • Analogy: The Registrar s Mutation • Proto Oncogene
Functions • Oncogenes and Clonal Proliferation • Mutations that
Convert Proto Oncogenes to Oncogenes • Genetic Structure of
Oncogenes • Summary • References
4 Tumor Suppressor Genes 45
Overview • Genetics of Tumor Suppressor Genes and Loss of
Heterozygosity (LOH) • Function of Tumor Suppressor Genes •
Summary • References
xi
xii Contents
5 Multiple Steps in the Molecular Causes of Cancer 57
Overview • Carcinogenesis • Chemoprotection from Cancer •
Angiogenesis • Tissue Invasion and Metastasis • Tumor Immun¬
ology • The Complexity of the Immune System—An
Aside • Summary of Part I (Chapters 1 5) • References
PART II Clinical Examples of Molecular Oncology
6 Molecular Diagnostics 75
Overview • Scale of Damage to DNA • Cytometry •
Chromosome Analysis • Gene Probes • Summary • References
7 Leukemia and Lymphoma 95
Overview • Molecular Evolution of a Leukemia •
Similar Molecular Events in Three Types of Lymphoma •
Summary • References
8 Colon Cancer Ill
Overview • Hereditary Colon Cancer • Molecular Evolution
of Colon Cancer • Carcinogenesis and Colon Cancer • Screening
and Early Detection • Molecular Staging • Molecular Therapies •
Summary • References
9 Squamous Cell Carcinoma of the Uterine Cervix 123
Overview • Cytologic Progression of Cervical Cancer •
Molecular Biology of Human Papilloma Virus (HPV) and Cervical
Cancer • Summary • References
10 Breast Cancer 135
Overview • Molecular Pathology • Staging and Multiple Prognostic
Factors • Breast Cancer Field Effect —A Special Problem •
Breast Cancer Susceptibility Genes • Summary • References
11 Molecular Anticancer Therapies 145
Overview • Molecular Targets in Cancer • Antisense Oligo
nucleotides • Immune Mediated Therapy • Infectious Vaccines—
An Aside • Genetic Engineering • Summary • References •
Conclusions 157
Glossary igo,
Index 165
|
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| language | English |
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| physical | XII, 168 S. Ill., graph. Darst. |
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| spelling | Ross, Dennis W. Verfasser aut Introduction to oncogenes and molecular cancer medicine Dennis W. Ross New York [u.a.] Springer 1998 XII, 168 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Moleculaire biologie gtt Oncogenen gtt Cancer Molecular aspects Cell Transformation, Neoplastic Neoplasms etiology Neoplasms genetics Oncogenes Onkogen (DE-588)4131118-8 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Molekularpathologie (DE-588)4170396-0 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Molekularbiologie (DE-588)4039983-7 s DE-604 Onkogen (DE-588)4131118-8 s Molekulare Medizin (DE-588)4543844-4 s Molekularpathologie (DE-588)4170396-0 s HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008282934&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ross, Dennis W. Introduction to oncogenes and molecular cancer medicine Moleculaire biologie gtt Oncogenen gtt Cancer Molecular aspects Cell Transformation, Neoplastic Neoplasms etiology Neoplasms genetics Oncogenes Onkogen (DE-588)4131118-8 gnd Molekulare Medizin (DE-588)4543844-4 gnd Molekularpathologie (DE-588)4170396-0 gnd Molekularbiologie (DE-588)4039983-7 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| subject_GND | (DE-588)4131118-8 (DE-588)4543844-4 (DE-588)4170396-0 (DE-588)4039983-7 (DE-588)4073781-0 |
| title | Introduction to oncogenes and molecular cancer medicine |
| title_auth | Introduction to oncogenes and molecular cancer medicine |
| title_exact_search | Introduction to oncogenes and molecular cancer medicine |
| title_full | Introduction to oncogenes and molecular cancer medicine Dennis W. Ross |
| title_fullStr | Introduction to oncogenes and molecular cancer medicine Dennis W. Ross |
| title_full_unstemmed | Introduction to oncogenes and molecular cancer medicine Dennis W. Ross |
| title_short | Introduction to oncogenes and molecular cancer medicine |
| title_sort | introduction to oncogenes and molecular cancer medicine |
| topic | Moleculaire biologie gtt Oncogenen gtt Cancer Molecular aspects Cell Transformation, Neoplastic Neoplasms etiology Neoplasms genetics Oncogenes Onkogen (DE-588)4131118-8 gnd Molekulare Medizin (DE-588)4543844-4 gnd Molekularpathologie (DE-588)4170396-0 gnd Molekularbiologie (DE-588)4039983-7 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| topic_facet | Moleculaire biologie Oncogenen Cancer Molecular aspects Cell Transformation, Neoplastic Neoplasms etiology Neoplasms genetics Oncogenes Onkogen Molekulare Medizin Molekularpathologie Molekularbiologie Krebs Medizin |
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