Intracranial germ cell tumors:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Wien [u.a.]
Springer
1998
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 369 S. Ill., graph. Darst. |
| ISBN: | 3211831274 |
Internformat
MARC
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| 245 | 1 | 0 | |a Intracranial germ cell tumors |c Yutaka Sawamura ... (eds.) |
| 264 | 1 | |a Wien [u.a.] |b Springer |c 1998 | |
| 300 | |a XIV, 369 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Brain Neoplasms |x diagnosis | |
| 650 | 4 | |a Brain Neoplasms |x therapy | |
| 650 | 4 | |a Brain |x Tumors | |
| 650 | 4 | |a Germ cells |x Tumors | |
| 650 | 4 | |a Germinoma |x diagnosis | |
| 650 | 4 | |a Germinoma |x therapy | |
| 650 | 4 | |a Pineal gland |x Tumors | |
| 650 | 4 | |a Teratoma |x diagnosis | |
| 650 | 4 | |a Teratoma |x therapy | |
| 650 | 0 | 7 | |a Germinom |0 (DE-588)4157018-2 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Germinom |0 (DE-588)4157018-2 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Sawamura, Yutaka |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008246099&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-008246099 | ||
Datensatz im Suchindex
| _version_ | 1804126784743014400 |
|---|---|
| adam_text | Contents
List of Contributors xiii
I. Introduction (N. de Tribolet) 1
II. WHO histological classification of tumors of the central
nervous system (CNS): germ cell tumors (GCTs)
(Y. Sawamura) 3
III. Epidemiology of CNS GCTs (M. Tada) 5
1. Histological variation and incidence 5
2. Racial and geographical factors 6
3. Age factor X
4. Gender factor 9
5. Anatomical factor 10
6. Genetic factor 12
7. Other factors 13
IV. Pathology (K. Meagher Villemure) 17
1. General features of GCTs 18
2. Germinoma 19
3. Embryonal carcinoma 23
4. Yolk sac tumor (Endodermal sinus tumor) 26
5. Choriocarcinoma 26
6. Teratomas 29
6.1 Mature teratoma 29
6.2 Immature teratoma 29
6.3 Teratoma with malignant elements 32
V. Immunobiology of tumor infiltrating lymphocytes (TIL)
in germinomas (M. Tada and Y. Sawamura) 37
1. Cell types of germinoma TIL 38
2. The cause and role of immune cell infiltration in
germinomas 40
3. Cytotoxicity of TIL to tumor cells 40
4. Conclusive remarks 41
VI. Genesis and genetics of intracranial germ cell tumors
(E. G. Van Mcir, J. W. Oostcrhuis, and L. H. ./. Looijenga). . . 45
1. Clonal evolution model for tumorigenesis 46
2. Oncogenes and tumor suppressor genes 49
3. Problematic of ontogenesis of CNS and extracranial GCTs 50
X Contents
Brain structures 205
Arteries 205
Cisterns 206
Choice of approach 207
Surgical techniques 211
Occipital transtentorial approach 213
Infratentorial supracerebellar approach 217
Complications 219
3. Stereotactic biopsy (/. Regis, O. Chinot, P. Bouillot,
H. Dufour, and J. C. Peragut) 221
3.1 Indications 223
3.2 Technical choices 223
3.3 Results 227
3.4 Stereotactic biopsy and the role of radiosurgery 233
XI. Chemotherapy for CNS GCTs (C. Balmaceda, S. Modak,
and J. L. Finley) 243
1. Overall view of chemotherapy for CNS GCTs 243
1.1 Rationale 243
1.2 Use of empirical chemotherapy for presumed
CNS GCTs 244
1.3 Chemotherapy for CNS metastases from systemic
GCTs 245
1.4 Chemotherapy for extraneural metastases of central
nervous system GCTs 246
2. Chemotherapy for recurrent CNS GCTs 246
2.1 Treatment for GCTs recurrent after irradiation 246
2.2 Treatment for GCTs recurrent after chemotherapy . . . 249
3. Chemotherapy for newly diagnosed CNS GCTs:
neoadjuvant chemotherapy 251
3.1 General 251
3.2 Neoadjuvant chemotherapy for CNS germinomas . . . 257
3.3 Neoadjuvant chemotherapy for non germinomatous
GCTs 258
3.4 Prospective multicenter trials of neoadjuvant
chemotherapy for CNS GCTs 260
3.4.1 Germinomas 260
3.4.2 Non germinomatous GCTs 263
3.5 Sandwich therapy for non germinomatous GCTs:
delayed surgical resection 266
3.6 The significance of residual masses after
chemotherapy treatment 267
Contents XI
4. Chemotherapy only trials 267
4.1 Germinomas 268
4.2 Non germinomatous GCTs 269
5. Predictors of outcome to treatment 270
6. Myeloablative chemotherapy followed by autologous
stem cell rescue for CNS GCTs 271
7. A view of the future 274
XII. Radiotherapy for CNS GCTs (//. Shirato) 283
1. Diagnostic radiotherapy or radiation test 283
2. Radiotherapy for CNS germinoma 283
2.1 History of the radiotherapy for CNS germinoma .... 284
2.2 Dose required to control primary tumor 285
2.2.1 Critical review of clinical studies 285
2.2.2 Dose reduction trials 289
3. Irradiation volume and technique 292
3.1 Craniospinal irradiation 295
3.1.1 Indication for CNS germinoma 295
3.1.2 Technical consideration for craniospinal
irradiation 296
3.2 Smaller field irradiation 298
3.3 Low dose small field irradiation following to
chemotherapy 299
3.4 HCG producing CNS germinoma 300
4. Radiotherapy for CNS non germinomatous GCTs 301
4.1 Mature teratoma 302
4.2 Immature teratoma 303
4.3 Teratoma with malignant transformation 304
4.4 Highly malignant non germinomatous GCTs 305
4.5 Mixed GCTs 307
5. Stereotactic irradiation (STI) 308
6. Future remarks 309
XIII. Adverse effect of therapy and late sequelae in survivors .... 317
1. Effect of external radiotherapy (H. Shirato and
Y. Sawamura) 317
1.1 Physical development 317
1.2 Neuropsychological sequelae 320
1.2.1 Histopathological findings 320
1.2.2 General observation after radiotherapy
for children 322
1.2.3 Findings after radiotherapy for CNS GCTs . . . 324
1.2.4 Prevention and follow up 328
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV012171368 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:22:58Z |
| institution | BVB |
| isbn | 3211831274 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008246099 |
| oclc_num | 39236376 |
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| physical | XIV, 369 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | Springer |
| record_format | marc |
| spelling | Intracranial germ cell tumors Yutaka Sawamura ... (eds.) Wien [u.a.] Springer 1998 XIV, 369 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Brain Neoplasms diagnosis Brain Neoplasms therapy Brain Tumors Germ cells Tumors Germinoma diagnosis Germinoma therapy Pineal gland Tumors Teratoma diagnosis Teratoma therapy Germinom (DE-588)4157018-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Germinom (DE-588)4157018-2 s DE-604 Sawamura, Yutaka Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008246099&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Intracranial germ cell tumors Brain Neoplasms diagnosis Brain Neoplasms therapy Brain Tumors Germ cells Tumors Germinoma diagnosis Germinoma therapy Pineal gland Tumors Teratoma diagnosis Teratoma therapy Germinom (DE-588)4157018-2 gnd |
| subject_GND | (DE-588)4157018-2 (DE-588)4143413-4 |
| title | Intracranial germ cell tumors |
| title_auth | Intracranial germ cell tumors |
| title_exact_search | Intracranial germ cell tumors |
| title_full | Intracranial germ cell tumors Yutaka Sawamura ... (eds.) |
| title_fullStr | Intracranial germ cell tumors Yutaka Sawamura ... (eds.) |
| title_full_unstemmed | Intracranial germ cell tumors Yutaka Sawamura ... (eds.) |
| title_short | Intracranial germ cell tumors |
| title_sort | intracranial germ cell tumors |
| topic | Brain Neoplasms diagnosis Brain Neoplasms therapy Brain Tumors Germ cells Tumors Germinoma diagnosis Germinoma therapy Pineal gland Tumors Teratoma diagnosis Teratoma therapy Germinom (DE-588)4157018-2 gnd |
| topic_facet | Brain Neoplasms diagnosis Brain Neoplasms therapy Brain Tumors Germ cells Tumors Germinoma diagnosis Germinoma therapy Pineal gland Tumors Teratoma diagnosis Teratoma therapy Germinom Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008246099&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT sawamurayutaka intracranialgermcelltumors |